Clinical and Developmental Immunology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Galectin-1 correlates with inflammatory markers and T regulatory cells in children with type 1 diabetes and/or celiac disease
In conclusion, the association observed between GAL-1, soluble immune markers and Treg cells may indicate a role for GAL-1 in the pathophysiology of T1D and, to some extent, also in CeD.PMID:38088456 | DOI:10.1093/cei/uxad131 (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - December 13, 2023 Category: Allergy & Immunology Authors: Emanuel Fryk Åsa Wilsson Andrea Tompa Per-Anders Jansson Maria Faresj ö Source Type: research

X-linked chronic granulomatous disease secondary to skewed X chromosome inactivation in female patients
Clin Exp Immunol. 2023 Dec 8:uxad129. doi: 10.1093/cei/uxad129. Online ahead of print.NO ABSTRACTPMID:38066563 | DOI:10.1093/cei/uxad129 (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - December 9, 2023 Category: Allergy & Immunology Authors: Yue Zhang Zhou Shu Yan Li Yurong Piao Fei Sun Tongxin Han Tianyou Wang Huawei Mao Source Type: research

Sicilian semi- and supercentenarians: age-related T γδ cell immunophenotype contributes to longevity trait definition
Clin Exp Immunol. 2023 Dec 8:uxad132. doi: 10.1093/cei/uxad132. Online ahead of print.ABSTRACTThe immune system of semi- (from ≥105 to <110 years old) and supercentenarians (≥110 years old), i.e., oldest centenarians, is thought to have characteristics that allow them to reach extreme longevity in relatively healthy status. Thus, we investigated variations of the two principal subsets of Tγδ, Vδ1 and Vδ2, and their functional subsets using the markers defining Tαβ cells, i.e., CD27, CD45RA, in a cohort of 28 women and 26 men (age range 19-110 years), including 11 Long living individuals (from >90 years old ...
Source: Clinical and Developmental Immunology - December 9, 2023 Category: Allergy & Immunology Authors: Mattia Emanuela Ligotti Giulia Accardi Anna Aiello Anna Calabr ò Calogero Caruso Anna Maria Corsale Francesco Dieli Marta Di Simone Serena Meraviglia Giuseppina Candore Source Type: research

Investigating dysregulation of TGF- β1/SMAD3 signaling in Atopic Dermatitis: A Molecular and Immunohistochemical Analysis"
Clin Exp Immunol. 2023 Dec 8:uxad130. doi: 10.1093/cei/uxad130. Online ahead of print.ABSTRACTAtopic Dermatitis (AD) is a persistent and recurring inflammatory condition affecting the skin. An expanding corpus of evidence indicates the potential participation of TGF-β1 in the modulation of inflammation and tissue remodeling in AD. The primary objective of this study was to examine the aberrant modulation of TGF-β1/SMAD3 signaling through a comprehensive analysis of their molecular and protein expression profiles. The study encompassed an aggregate of 37 participants, which included 25 AD patients and 12 controls. The ass...
Source: Clinical and Developmental Immunology - December 9, 2023 Category: Allergy & Immunology Authors: Tabasum Shafi Roohi Rasool Showkat Hussain Imtiyaz A Bhat Rumana Makhdoomi Sheikh Adil Bashir Iffat Hassan Zafar A Shah Source Type: research