Quantitative Sensory Testing Defines the Trajectory of Sensory Neuropathy after Severe COVID-19
CONCLUSIONS: Severe COVID-19 is associated with abnormal vibration and thermal thresholds which are sustained for up to 1 year in patients with diabetes. Abnormal sensory thresholds have no association with long-COVID development.PMID:38007044 | DOI:10.1016/j.diabres.2023.111029 (Source: Clin Med Res)
Source: Clin Med Res - November 25, 2023 Category: Research Authors: Georgios Ponirakis Ariel Odriozola Luc ía Ortega Lidia Martinez Samantha Odriozola Ainhoa Torrens David Coroleu Silvia Mart ínez Xavier Sanz Meritxell Ponce Yolanda Meije Mercedes Clemente Alejandra Duarte M Bel én Odriozola Rayaz A Malik Source Type: research

Quantitative Sensory Testing Defines the Trajectory of Sensory Neuropathy after Severe COVID-19
CONCLUSIONS: Severe COVID-19 is associated with abnormal vibration and thermal thresholds which are sustained for up to 1 year in patients with diabetes. Abnormal sensory thresholds have no association with long-COVID development.PMID:38007044 | DOI:10.1016/j.diabres.2023.111029 (Source: Clin Med Res)
Source: Clin Med Res - November 25, 2023 Category: Research Authors: Georgios Ponirakis Ariel Odriozola Luc ía Ortega Lidia Martinez Samantha Odriozola Ainhoa Torrens David Coroleu Silvia Mart ínez Xavier Sanz Meritxell Ponce Yolanda Meije Mercedes Clemente Alejandra Duarte M Bel én Odriozola Rayaz A Malik Source Type: research

Quantitative Sensory Testing Defines the Trajectory of Sensory Neuropathy after Severe COVID-19
CONCLUSIONS: Severe COVID-19 is associated with abnormal vibration and thermal thresholds which are sustained for up to 1 year in patients with diabetes. Abnormal sensory thresholds have no association with long-COVID development.PMID:38007044 | DOI:10.1016/j.diabres.2023.111029 (Source: Clin Med Res)
Source: Clin Med Res - November 25, 2023 Category: Research Authors: Georgios Ponirakis Ariel Odriozola Luc ía Ortega Lidia Martinez Samantha Odriozola Ainhoa Torrens David Coroleu Silvia Mart ínez Xavier Sanz Meritxell Ponce Yolanda Meije Mercedes Clemente Alejandra Duarte M Bel én Odriozola Rayaz A Malik Source Type: research

Quantitative Sensory Testing Defines the Trajectory of Sensory Neuropathy after Severe COVID-19
CONCLUSIONS: Severe COVID-19 is associated with abnormal vibration and thermal thresholds which are sustained for up to 1 year in patients with diabetes. Abnormal sensory thresholds have no association with long-COVID development.PMID:38007044 | DOI:10.1016/j.diabres.2023.111029 (Source: Clin Med Res)
Source: Clin Med Res - November 25, 2023 Category: Research Authors: Georgios Ponirakis Ariel Odriozola Luc ía Ortega Lidia Martinez Samantha Odriozola Ainhoa Torrens David Coroleu Silvia Mart ínez Xavier Sanz Meritxell Ponce Yolanda Meije Mercedes Clemente Alejandra Duarte M Bel én Odriozola Rayaz A Malik Source Type: research

Angiography-based coronary microvascular assessment with and without intracoronary pressure measurements: a systematic review
CONCLUSION: Our findings suggest that combined angiography- and pressure-based methods provide a more reliable assessment of microvascular resistance compared to methods relying solely on angiography. Central illustration. Comparative assessment of image-based methods quantifying microvascular resistance with and without intracoronary pressure measurements. Angiography-based methods rely on angiography alone to calculate the microvascular resistance by utilizing angiographic frame counting to extrapolate coronary flow (Q) and subsequently deriving distal coronary pressure using fluid dynamic equations. Combined angiography...
Source: Clin Med Res - November 21, 2023 Category: Research Authors: Michael Kest Andr ás Ágoston G ábor Tamás Szabó Attila Kiss Áron Üveges D ániel Czuriga Andr ás Komócsi Istv án Hizoh Zsolt K őszegi Source Type: research

Angiography-based coronary microvascular assessment with and without intracoronary pressure measurements: a systematic review
CONCLUSION: Our findings suggest that combined angiography- and pressure-based methods provide a more reliable assessment of microvascular resistance compared to methods relying solely on angiography. Central illustration. Comparative assessment of image-based methods quantifying microvascular resistance with and without intracoronary pressure measurements. Angiography-based methods rely on angiography alone to calculate the microvascular resistance by utilizing angiographic frame counting to extrapolate coronary flow (Q) and subsequently deriving distal coronary pressure using fluid dynamic equations. Combined angiography...
Source: Clin Med Res - November 21, 2023 Category: Research Authors: Michael Kest Andr ás Ágoston G ábor Tamás Szabó Attila Kiss Áron Üveges D ániel Czuriga Andr ás Komócsi Istv án Hizoh Zsolt K őszegi Source Type: research

Angiography-based coronary microvascular assessment with and without intracoronary pressure measurements: a systematic review
CONCLUSION: Our findings suggest that combined angiography- and pressure-based methods provide a more reliable assessment of microvascular resistance compared to methods relying solely on angiography. Central illustration. Comparative assessment of image-based methods quantifying microvascular resistance with and without intracoronary pressure measurements. Angiography-based methods rely on angiography alone to calculate the microvascular resistance by utilizing angiographic frame counting to extrapolate coronary flow (Q) and subsequently deriving distal coronary pressure using fluid dynamic equations. Combined angiography...
Source: Clin Med Res - November 21, 2023 Category: Research Authors: Michael Kest Andr ás Ágoston G ábor Tamás Szabó Attila Kiss Áron Üveges D ániel Czuriga Andr ás Komócsi Istv án Hizoh Zsolt K őszegi Source Type: research

Angiography-based coronary microvascular assessment with and without intracoronary pressure measurements: a systematic review
CONCLUSION: Our findings suggest that combined angiography- and pressure-based methods provide a more reliable assessment of microvascular resistance compared to methods relying solely on angiography. Central illustration. Comparative assessment of image-based methods quantifying microvascular resistance with and without intracoronary pressure measurements. Angiography-based methods rely on angiography alone to calculate the microvascular resistance by utilizing angiographic frame counting to extrapolate coronary flow (Q) and subsequently deriving distal coronary pressure using fluid dynamic equations. Combined angiography...
Source: Clin Med Res - November 21, 2023 Category: Research Authors: Michael Kest Andr ás Ágoston G ábor Tamás Szabó Attila Kiss Áron Üveges D ániel Czuriga Andr ás Komócsi Istv án Hizoh Zsolt K őszegi Source Type: research

Outcomes of Transjugular Intrahepatic Portosystemic Shunt and Gastric Coronary Vein Embolization for Variceal Bleeding in Cirrhotic Portal Hypertension
Conclusion: The results suggest that TIPS combined with GCVE is effective and safer in the treatment of cirrhotic portal hypertensive variceal bleeding. The use of TIP plus GCVE as first-line treatment, may be preferable for high-risk re-bleeding, and more than 25 mm Hg portal venous pressure with repeated variceal bleeding. However, the sample size was small. Therefore, large, randomized, controlled, multidisciplinary center studies are needed for further evaluation.PMID:37985166 | DOI:10.3121/cmr.2023.1796 (Source: Clin Med Res)
Source: Clin Med Res - November 20, 2023 Category: Research Authors: Gauri Mukhiya Xinwei Han Dechao Jiao Yonghua Bi Gaurab Pokhrel Zaoqu Liu Zhaonan Li Yongfu He Source Type: research

Diagnosis of Irritable Bowel Syndrome: Primary Care Physicians Compared with Gastroenterologists
Conclusion: The sensitivity of gastroenterologist diagnosis of IBS closely matches the sensitivity of Rome IV criteria in validation studies. The high specificity and PPV of gastroenterologists suggest more cautious diagnosis by gastroenterologists, with PCPs more likely to assign a diagnosis of IBS incorrectly or without sufficient documentation of symptoms fulfilling Rome IV criteria. Reported resolution rates suggest primary care management of IBS is appropriate, but PCPs may benefit from gastroenterologist consultation and diagnostic guidelines for greater specificity in diagnosing IBS.PMID:37985167 | DOI:10.3121/cmr.2...
Source: Clin Med Res - November 20, 2023 Category: Research Authors: Genevieve Pareki Amy Wozniak Ayokunle Temidayo Abegunde Source Type: research

Primary Epiploic Appendagitis: A Mimicker of Abdominal Pain
We present a case of a 65-year-old male with a history of diverticulitis, presenting with left lower quadrant abdominal pain who was diagnosed with PEA based on CT and successfully managed with conservative treatment.PMID:37985168 | DOI:10.3121/cmr.2023.1837 (Source: Clin Med Res)
Source: Clin Med Res - November 20, 2023 Category: Research Authors: Matthew Patel Imran Haider Andrew Cheung Source Type: research

A Comparative Analysis of Perioperative Complications in Octogenarians and Patients under 60 Years of Age after Primary Cemented Total Knee Arthroplasty
Conclusion: The study shows that primary cemented knee arthroplasty is a safe procedure without an increased incidence of surgical complications, even in elderly patients. The increased incidence of internal complications in octogenarians, in turn, should receive more attention in the perioperative course. The interdisciplinary preoperative optimization of pre-existing conditions and drug therapy, as well as close interdisciplinary assessments of elderly patients, should be ensured.PMID:37985169 | DOI:10.3121/cmr.2023.1810 (Source: Clin Med Res)
Source: Clin Med Res - November 20, 2023 Category: Research Authors: Julian Koettnitz Jan Isbeih Christian D Peterlein Filippo Migliorini Christian G ötze Source Type: research

Outcomes of Localized Renal Cell Carcinoma Across Different Races
This study aims to compare preoperative characteristics, surgical outcomes, and oncological outcomes of RCC patients at a urology unit in Singapore.Methods: A retrospective cohort analysis of 137 RCC patients in the National University Hospital of Singapore who had undergone partial nephrectomy between 2009 and 2020 was conducted. χ2 tests (Chi-Square Test, Fisher's Exact Test) and one-way analysis of variance (ANOVA) were used for comparing categorical and continuous variables respectively. Kaplan-Meier estimates were used for survival analysis.Results: In total, 137 patients were identified (Chinese [n=82], Malay [n=19]...
Source: Clin Med Res - November 20, 2023 Category: Research Authors: Wei Zheng So Khi Yung Fong Ziting Wang Ho Yee Tiong Source Type: research

HLH and TET2 Mutation Presenting after First Cycle of CLL Treatment
Clin Med Res. 2023 Sep;21(3):155-158. doi: 10.3121/cmr.2023.1804.ABSTRACTHere we report development of hemophagocytic lymphohistiocytosis (HLH), along with unmasking of a TET2-mutated myeloid neoplasm, after initial doses of bendamustine and rituximab for longstanding chronic lymphocytic leukemia (CLL). After many years of CLL showing minimally progressive lymphocytosis, the patient's white blood cell count began to decline in parallel with neutrophil count, hemoglobin, and platelet count. Bone marrow biopsy showed partial CLL involvement; bendamustine+rituximab therapy was augmented with granulocyte colony-stimulating fac...
Source: Clin Med Res - November 20, 2023 Category: Research Authors: Allison J Geiger Demet Gokalp Yasar Kajal V Sitwala Source Type: research

The Link Between COVID-19 and Alzheimer Disease Through Neuroinflammation
Clin Med Res. 2023 Sep;21(3):119-121. doi: 10.3121/cmr.2023.1841.NO ABSTRACTPMID:37985172 | DOI:10.3121/cmr.2023.1841 (Source: Clin Med Res)
Source: Clin Med Res - November 20, 2023 Category: Research Authors: Ali Nouraeinejad Source Type: research