Macromolecular Complex Including MLL3, Carabin and Calcineurin Regulates Cardiac Remodeling
CONCLUSIONS: Our study reveals an unsuspected epigenetic mechanism of CaN that directly regulates MLL3 histone methyl transferase activity to promote cardiac remodeling.PMID:38084599 | DOI:10.1161/CIRCRESAHA.123.323458 (Source: Circulation Research)
Source: Circulation Research - December 12, 2023 Category: Cardiology Authors: Roberto Pane Loubna Laib Karina Formoso Maximin D étrait Yannis Sainte-Marie Florence Bourgailh Nolan Ruffenach Hanam ée Faugeras Ilias Simon Emeline Lhuillier Frank Lezoualc'h Caroline Conte Source Type: research
LncRNA < em > PSMB8-AS1 < /em > Instigates Vascular Inflammation to Aggravate Atherosclerosis
CONCLUSIONS: PSMB8-AS1 promotes vascular inflammation and atherosclerosis via the NONO/PSMB9/ZEB1 axis. Our findings support the development of new long noncoding RNA-based strategies to counteract atherosclerotic cardiovascular disease.PMID:38084631 | DOI:10.1161/CIRCRESAHA.122.322360 (Source: Circulation Research)
Source: Circulation Research - December 12, 2023 Category: Cardiology Authors: Shu Li Run-Chao He Shao-Guo Wu Yu Song Ke-Lan Zhang Mao-Lin Tang Yan-Rou Bei Ting Zhang Jin-Bo Lu Xin Ma Min Jiang Liang-Jun Qin Yudan Xu Xian-Hui Dong Jia Wu Xiaoyan Dai Yan-Wei Hu Source Type: research
Meet the First Authors
Circ Res. 2023 Dec 8;133(12):964-965. doi: 10.1161/RES.0000000000000648. Epub 2023 Dec 7.NO ABSTRACTPMID:38060680 | DOI:10.1161/RES.0000000000000648 (Source: Circulation Research)
Source: Circulation Research - December 7, 2023 Category: Cardiology Source Type: research
Late-Breaking Basic Science Abstracts From the American Heart Association's Scientific Sessions 2023
Circ Res. 2023 Dec 8;133(12):e54-e68. doi: 10.1161/RES.0000000000000644. Epub 2023 Dec 7.NO ABSTRACTPMID:38060682 | DOI:10.1161/RES.0000000000000644 (Source: Circulation Research)
Source: Circulation Research - December 7, 2023 Category: Cardiology Source Type: research
RNA Modification That Breaks the Heart: RNA Acetylase Nat10 Promotes Fibrosis
Circ Res. 2023 Dec 8;133(12):1003-1005. doi: 10.1161/CIRCRESAHA.123.323866. Epub 2023 Dec 7.NO ABSTRACTPMID:38060683 | DOI:10.1161/CIRCRESAHA.123.323866 (Source: Circulation Research)
Source: Circulation Research - December 7, 2023 Category: Cardiology Authors: Leo Kurian Ralf P Brandes Source Type: research
