Early Career Research Support From the American Heart Association: to the Second Century and Beyond
Circ Res. 2024 Mar;134(5):478-481. doi: 10.1161/CIRCRESAHA.123.323060. Epub 2024 Feb 29.NO ABSTRACTPMID:38422179 | DOI:10.1161/CIRCRESAHA.123.323060 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Jessica Pfleger Ronald J Vagnozzi Source Type: research

Unveiling the Spatiotemporal Diversity of the Endothelium in Development: A Multi-Omics Approach
Circ Res. 2024 Mar;134(5):547-549. doi: 10.1161/CIRCRESAHA.124.324328. Epub 2024 Feb 29.NO ABSTRACTPMID:38422180 | PMC:PMC10906738 | DOI:10.1161/CIRCRESAHA.124.324328 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Roy Jung Chinmay M Trivedi Source Type: research

Correction to: Unleashing the Power of Genetics: PLN Ablation, Phospholambanopathies and Evolving Challenges
Circ Res. 2024 Mar;134(5):e16. doi: 10.1161/RES.0000000000000660. Epub 2024 Feb 29.NO ABSTRACTPMID:38422181 | DOI:10.1161/RES.0000000000000660 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Source Type: research

B-Cell Immune Checkpoints Come of Age in Cardio-oncology
Circ Res. 2024 Mar;134(5):569-571. doi: 10.1161/CIRCRESAHA.124.324243. Epub 2024 Feb 29.NO ABSTRACTPMID:38422182 | DOI:10.1161/CIRCRESAHA.124.324243 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Alan Gutierrez Javid J Moslehi Source Type: research

Ponatinib-Induced Cardiomyocyte Toxicity: Dark Side of the Integrated Stress Response
Circ Res. 2024 Mar;134(5):502-504. doi: 10.1161/CIRCRESAHA.124.324164. Epub 2024 Feb 29.NO ABSTRACTPMID:38422183 | PMC:PMC10906736 | DOI:10.1161/CIRCRESAHA.124.324164 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Felix G Liang Javid Moslehi Richard N Kitsis Source Type: research

Monocytes Release Pro-Cathepsin D to Drive Blood-to-Brain Transcytosis in Diabetes
CONCLUSIONS: These findings uncover the novel role of circulatory pro-CTSD from monocytes in the pathogenesis of cerebral microvascular lesions in diabetes. The circulatory pro-CTSD is a potential target for the intervention of microvascular complications in diabetes.PMID:38420756 | DOI:10.1161/CIRCRESAHA.123.323622 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Dan Zhao Zeng-Kang Huang Yu Liang Zhi-Jun Li Xue-Wei Zhang Kun-Hang Li Hao Wu Xu-Dong Zhang Chen-Sheng Li Dong An Xue Sun Ming-Xin An Jun-Xiu Shi Yi-Jun Bao Li Tian Di-Fei Wang An-Hua Wu Yu-Hua Chen Wei-Dong Zhao Source Type: research

PIEZO Ion Channels in Cardiovascular Functions and Diseases
Circ Res. 2024 Mar;134(5):572-591. doi: 10.1161/CIRCRESAHA.123.322798. Epub 2024 Feb 29.ABSTRACTThe cardiovascular system provides blood supply throughout the body and as such is perpetually applying mechanical forces to cells and tissues. Thus, this system is primed with mechanosensory structures that respond and adapt to changes in mechanical stimuli. Since their discovery in 2010, PIEZO ion channels have dominated the field of mechanobiology. These have been proposed as the long-sought-after mechanosensitive excitatory channels involved in touch and proprioception in mammals. However, more and more pieces of evidence po...
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Bertrand Coste Patrick Delmas Source Type: research

Meet the First Authors
Circ Res. 2024 Mar;134(5):476-477. doi: 10.1161/RES.0000000000000665. Epub 2024 Feb 29.NO ABSTRACTPMID:38422174 | DOI:10.1161/RES.0000000000000665 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Source Type: research

Cardiovascular Consequences of Uremic Metabolites: an Overview of the Involved Signaling Pathways
Circ Res. 2024 Mar;134(5):592-613. doi: 10.1161/CIRCRESAHA.123.324001. Epub 2024 Feb 29.ABSTRACTThe crosstalk of the heart with distant organs such as the lung, liver, gut, and kidney has been intensively approached lately. The kidney is involved in (1) the production of systemic relevant products, such as renin, as part of the most essential vasoregulatory system of the human body, and (2) in the clearance of metabolites with systemic and organ effects. Metabolic residue accumulation during kidney dysfunction is known to determine cardiovascular pathologies such as endothelial activation/dysfunction, atherosclerosis, card...
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Adelina Curaj Raymond Vanholder Joseph Loscalzo Kaiseng Quach Zhuojun Wu Vera Jankowski Joachim Jankowski Source Type: research

Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis
CONCLUSION: NMN preserves heart function during lipid overload by preventing v-ATPase disassembly.PMID:38422177 | DOI:10.1161/CIRCRESAHA.123.322910 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Shujin Wang Yinying Han Ruimin Liu Mengqian Hou Dietbert Neumann Jun Zhang Fang Wang Yumeng Li Xueya Zhao Francesco Schianchi Chao Dai Lizhong Liu Miranda Nabben Jan F C Glatz Xin Wu Xifeng Lu Xi Li Joost J F P Luiken Source Type: research

Preventing the Fatty Acid-Transporter CD36 From Taking its Toll on the Heart
Circ Res. 2024 Mar;134(5):526-528. doi: 10.1161/CIRCRESAHA.123.323945. Epub 2024 Feb 29.NO ABSTRACTPMID:38422178 | DOI:10.1161/CIRCRESAHA.123.323945 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Mathias Mericskay Source Type: research

Early Career Research Support From the American Heart Association: to the Second Century and Beyond
Circ Res. 2024 Mar;134(5):478-481. doi: 10.1161/CIRCRESAHA.123.323060. Epub 2024 Feb 29.NO ABSTRACTPMID:38422179 | DOI:10.1161/CIRCRESAHA.123.323060 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Jessica Pfleger Ronald J Vagnozzi Source Type: research

Unveiling the Spatiotemporal Diversity of the Endothelium in Development: A Multi-Omics Approach
Circ Res. 2024 Mar;134(5):547-549. doi: 10.1161/CIRCRESAHA.124.324328. Epub 2024 Feb 29.NO ABSTRACTPMID:38422180 | DOI:10.1161/CIRCRESAHA.124.324328 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Roy Jung Chinmay M Trivedi Source Type: research

Correction to: Unleashing the Power of Genetics: PLN Ablation, Phospholambanopathies and Evolving Challenges
Circ Res. 2024 Mar;134(5):e16. doi: 10.1161/RES.0000000000000660. Epub 2024 Feb 29.NO ABSTRACTPMID:38422181 | DOI:10.1161/RES.0000000000000660 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Source Type: research

B-Cell Immune Checkpoints Come of Age in Cardio-oncology
Circ Res. 2024 Mar;134(5):569-571. doi: 10.1161/CIRCRESAHA.124.324243. Epub 2024 Feb 29.NO ABSTRACTPMID:38422182 | DOI:10.1161/CIRCRESAHA.124.324243 (Source: Circulation Research)
Source: Circulation Research - February 29, 2024 Category: Cardiology Authors: Alan Gutierrez Javid J Moslehi Source Type: research