Correction [Correction]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 26, 2017 Category: Cardiology Tags: Correction Source Type: research
Long-Term Pathological Follow-Up of Myocardium in a Carrier of Duchenne Muscular Dystrophy With Dilated Cardiomyopathy [Images and Case Reports in Heart Failure]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 23, 2017 Category: Cardiology Authors: Kondo, T., Okumura, T., Takefuji, M., Hiraiwa, H., Sugiura, Y., Watanabe, N., Aoki, S., Ichii, T., Kitagawa, K., Kano, N., Fukaya, K., Furusawa, K., Sawamura, A., Morimoto, R., Bando, Y. K., Takemura, G., Murohara, T. Tags: Cardiomyopathy Images and Case Reports in Heart Failure Source Type: research
Worsening Renal Function and Mortality in Heart Failure: Causality or Confounding? [Editorial]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 15, 2017 Category: Cardiology Authors: Testani, J. M., Brisco-Bacik, M. A. Tags: Cardiorenal Syndrome, Mortality/Survival Editorial Source Type: research
Ideal Cardiovascular Health, Cardiovascular Remodeling, and Heart Failure in Blacks: The Jackson Heart Study [Original Article]
Conclusions—
Cardiovascular risk factors in midlife (specifically elevated blood pressure, physical inactivity, smoking, and poor glucose control) are associated with incident HF in blacks and represent targets for intensified HF prevention. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 15, 2017 Category: Cardiology Authors: Spahillari, A., Talegawkar, S., Correa, A., Carr, J. J., Terry, J. G., Lima, J., Freedman, J. E., Das, S., Kociol, R., de Ferranti, S., Mohebali, D., Mwasongwe, S., Tucker, K. L., Murthy, V. L., Shah, R. V. Tags: Epidemiology, Obesity, Computerized Tomography (CT), Magnetic Resonance Imaging (MRI) Original Article Source Type: research
Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis [Original Article]
Conclusions—
CgA-to-CST conversion in HF is impaired because of hyperglycosylation, which is associated with clinical outcomes in acute HF. The mechanism for increased mortality may be dysregulated cardiomyocyte Ca2+ handling because of reduced CaMKII inhibition. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 15, 2017 Category: Cardiology Authors: Ottesen, A. H., Carlson, C. R., Louch, W. E., Dahl, M. B., Sandbu, R. A., Johansen, R. F., Jarstadmarken, H., Bjoras, M., Hoiseth, A. D., Brynildsen, J., Sjaastad, I., Stridsberg, M., Omland, T., Christensen, G., Rosjo, H. Tags: Biomarkers, Calcium Cycling/Excitation-Contraction Coupling, Mechanisms, Translational Studies, Heart Failure Original Article Source Type: research
Renin-Angiotensin System Inhibition, Worsening Renal Function, and Outcome in Heart Failure Patients With Reduced and Preserved Ejection Fraction: A Meta-Analysis of Published Study Data [Original Article]
Conclusions—
RAAS inhibitors induce renal dysfunction in both HFREF and HFPEF. However, in contrast to patients with HFREF where mortality increase with WRF is small, HFPEF patients with RAAS inhibitor–induced WRF have an increased mortality risk, without experiencing improved outcome with RAAS inhibition. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 15, 2017 Category: Cardiology Authors: Beldhuis, I. E., Streng, K. W., Ter Maaten, J. M., Voors, A. A., van der Meer, P., Rossignol, P., McMurray, J. J. V., Damman, K. Tags: Pharmacology, Meta Analysis, Mortality/Survival Original Article Source Type: research
H-Ras Isoform Mediates Protection Against Pressure Overload-Induced Cardiac Dysfunction in Part Through Activation of AKT [Original Articles]
Conclusions—
Taken together, these findings indicate that H- and K-Ras have divergent effects on cardiac hypertrophy and heart failure in response to pressure overload stress. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 12, 2017 Category: Cardiology Authors: Matsuda, T., Jeong, J. I., Ikeda, S., Yamamoto, T., Gao, S., Babu, G. J., Zhai, P., Del Re, D. P. Tags: Cell Signaling/Signal Transduction, Heart Failure, Hypertrophy, Hypertension Original Articles Source Type: research
Ventricular Thrombosis Post-Venoarterial Extracorporeal Membrane Oxygenation [Images and Case Reports in Heart Failure]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 9, 2017 Category: Cardiology Authors: Alhussein, M., Moayedi, Y., Posada, J. D., Ross, H., Hickey, E., Rao, V., Billia, F. Tags: Cardiomyopathy, Heart Failure Images and Case Reports in Heart Failure Source Type: research
Novel Dominant-Negative Mutation in Cardiac Troponin I Causes Severe Restrictive Cardiomyopathy [Images and Case Reports in Heart Failure]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 6, 2017 Category: Cardiology Authors: Shah, S., Yogasundaram, H., Basu, R., Wang, F., Paterson, D. I., Alastalo, T.-P., Oudit, G. Y. Tags: Cell Biology/Structural Biology, Myocardial Biology, Cardiomyopathy, Heart Failure Images and Case Reports in Heart Failure Source Type: research
Aortic Waveform Analysis to Individualize Treatment in Heart Failure [Original Article]
Conclusions—
Increased aortic pressure wave pulsatility and greater decrease in pulsatility on treatment are associated with functional improvement in patients with HF and reduced ejection fraction receiving aggressive vasodilator titration. These differences are not identifiable using brachial cuff pressures. Central aortic waveform analysis may enable better individualization of vasoactive therapies in chronic HF and reduced ejection fraction.
Clinical Trial Registration—
URL: http://www.clinicaltrials.gov. Unique identifier: NCT00588692. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 2, 2017 Category: Cardiology Authors: Wohlfahrt, P., Melenovsky, V., Redfield, M. M., Olson, T. P., Lin, G., Abdelmoneim, S. S., Hametner, B., Wassertheurer, S., Borlaug, B. A. Tags: Heart Failure, Hypertension Original Article Source Type: research
Serum Chloride and Sodium Interplay in Patients With Acute Myocardial Infarction and Heart Failure With Reduced Ejection Fraction: An Analysis From the High-Risk Myocardial Infarction Database Initiative [Original Article]
Conclusions—
In post–myocardial infarction with systolic dysfunction and HF, low serum chloride was associated with mortality (but not hospitalization for HF) in the setting of lower sodium. Overall, chloride and its interaction with sodium did not add clinically relevant prognostic information on top of other well-established prognostic variables. Taken together, these data support an integrated and critical consideration of chloride and sodium interplay. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 2, 2017 Category: Cardiology Authors: Ferreira, J. P., Girerd, N., Duarte, K., Coiro, S., McMurray, J. J. V., Dargie, H. J., Pitt, B., Dickstein, K., Testani, J. M., Zannad, F., Rossignol, P., for the High-Risk Myocardial Infarction Database Initiative Investigators Tags: Heart Failure, Myocardial Infarction, Mortality/Survival Original Article Source Type: research
Impact of Ultrafiltration on Serum Sodium Homeostasis and its Clinical Implication in Patients With Acute Heart Failure, Congestion, and Worsening Renal Function [Original Article]
Conclusions—
Fluid removal by ultrafiltration was associated with a decrease in serum sodium levels compared with diuretic treatment but returned to baseline levels at day 30. Discharge hyponatremia but not treatment-induced hyponatremia was associated with worse clinical outcomes.
Clinical Trial Registration—
URL: http://www.clinicaltrials.gov. Unique identifier: NCT00608491. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 26, 2017 Category: Cardiology Authors: Kitai, T., Grodin, J. L., Kim, Y.-H., Tang, W. H. W. Tags: Cardiorenal Syndrome, Heart Failure Original Article Source Type: research
Editorial Board [Editorial Board]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 16, 2017 Category: Cardiology Tags: Editorial Board Source Type: research
Rethinking Revascularization in Left Ventricular Systolic Dysfunction [Editorial]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 12, 2017 Category: Cardiology Authors: DeVore, A. D., Velazquez, E. J. Tags: Chronic Ischemic Heart Disease, Heart Failure Editorial Source Type: research
Thirty Years of Evidence on the Efficacy of Drug Treatments for Chronic Heart Failure With Reduced Ejection Fraction: A Network Meta-Analysis [Original Articles]
Conclusions—
The network meta-analysis showed that treatment with ACEI, ARB, BB, MRA, and ARNI and their combinations were better than the treatment with placebo in reducing all-cause mortality, with the exception of ARB monotherapy and ARB plus ACEI. The combination of ARNI+BB+MRA resulted in the greatest mortality reduction. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 12, 2017 Category: Cardiology Authors: Burnett, H., Earley, A., Voors, A. A., Senni, M., McMurray, J. J. V., Deschaseaux, C., Cope, S. Tags: Heart Failure, Treatment, Meta Analysis, Mortality/Survival Original Articles Source Type: research
