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Abstract 128: A Precision Medicine Test Accurately Rules Out Obstructive Coronary Artery Disease Among Non-Diabetic Patients Presenting to Emergency Department With Acute Chest Pain [Session Title: Poster Session AM]
Conclusions: This is the first study validating the use of this blood-based precision medicine test to rule out obstructive CAD among low-intermediate risk non-diabetic patients presenting with ACP in ED setting. 30-day follow-up is underway to evaluate the prognostic implications of these findings. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Nasir, K., Ali, S. S., Saxena, A., Grandhi, G., Siddiqui, U., Kuo, J. Z., Wingrove, J. A., Johnson, A., Monane, M., Arias, L., Veledar, E. Tags: Session Title: Poster Session AM Source Type: research

Abstract 127: Risk Factors for Cardiovascular Disease in Heterozygous Familial Hypercholesterolemia: A Systematic Review and Meta-analysis [Session Title: Poster Session AM]
Conclusions: Several clinical risk factors are significantly and independently associated with CVD risk in patients with FH and should be targeted for risk factor modification. These data can also inform the selection of variables for prediction models to aid in risk stratifying patients. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Akioyamen, L., Genest, J., Chu, A., Inibhunu, H., Tu, J. V. Tags: Session Title: Poster Session AM Source Type: research

Abstract 126: Effect of Immunosuppressive Therapy, Clinical, and Demographic Parameters on Kidney Function After Cadaveric Renal Transplant [Session Title: Poster Session AM]
Conclusions: Higher Hgb levels and triple immune-suppressive therapy are associated with improved kidney function post-renal transplant. Additional studies are needed to identify causes of decreased hemoglobin in this patient population and to develop treatment strategies aimed at preserving GFR. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Muste, J., Pashkovetsky, E., Wang, S., Misak, M., Chandolias, N., Lopez-Soler, R., Conti, D., Torosoff, M. Tags: Session Title: Poster Session AM Source Type: research

Abstract 125: Fewer Hospitalizations And Emergency Room Visits With Sacubitril/Valsartan Versus Angiotensin-Converting Enzyme Inhibitor Or Angiotensin-Receptor Blocker In A Retrospective Claims-Based Study Of Patients With Heart Failure [Session Title: Poster Session AM]
Conclusions: Based on a real-world sample of patients with HFrEF, those initiated with SAC/VAL ≤12 months following US market approval experienced fewer monthly hospitalizations and ER visits compared to ACEI/ARB, and no difference in ambulatory visits. Lower risk of hospitalization after initiating SAC/VAL, rather than using ACEI/ARB, is important since HF hospitalization was previously associated with higher 30-60 day mortality and readmission rate. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Albert, N. M., Swindle, J. P., Buysman, E. K., Chang, C. Tags: Session Title: Poster Session AM Source Type: research

Abstract 124: Glycemic Control and Medication Adherence in Diabetic Patients After Myocardial Infarction [Session Title: Poster Session AM]
Conclusion: While medication adherence overall declined with worsening glycemic control, the greatest differences are seen in those with a HbA1c ≥9%. Thus, targeting optimal medical therapy adherence, in addition to glycemic control, could benefit those with poorly-controlled diabetes after MI. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Ramadurai, D., Adamek, K., Gunzburger, E., Ho, P. M., Raghavan, S. Tags: Session Title: Poster Session AM Source Type: research

Abstract 123: Revascularization Rate and Associated Costs Among Patients With Stable Ischemic Heart Disease Initiating Ranolazine versus Traditional Antianginals [Session Title: Poster Session AM]
Conclusions: Frequency of revascularization procedures and associated healthcare costs were lower among patients with SIHD initiating ranolazine compared to patients initiating BB or LAN as antianginal therapy, and comparable to patients initiating CCBs. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Meyer, N., Tran, O., Hartsfield, C., Nguyen, L., Kazi, D., Koch, B. Tags: Session Title: Poster Session AM Source Type: research

Abstract 122: Comparative Effectiveness of Primary Prevention Implantable Cardioverter-Defibrillators in Older Adults With Diabetes Mellitus: Insights From the Get With the Guidelines - Heart Failure Registry [Session Title: Poster Session AM]
Conclusion: Among patients with HFrEF, primary prevention ICD was associated with reduced mortality in patients with and without diabetes. These findings support current guideline recommendation for primary prevention ICDs among eligible patients with DM. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Sharma, A., Wu, J., Hernandez, A. F., Felker, G. M., Al-Khatib, S., Green, J., Matsouaka, R., Fonarow, G., Singh, J., Ezekowitz, J., Heidenreich, P., DeVore, A. D. Tags: Session Title: Poster Session AM Source Type: research

Abstract 121: Anxiety and Depression in Patients With Fibromuscular Dysplasia: A Report From the US Registry for Fibromuscular Dysplasia [Session Title: Poster Session AM]
Conclusions: More than 1/3 of patients in the FMD registry had A, D, or both, and these patients showed multiple differences compared to patients without A/D. More study is required to understand this relationship. Given the high prevalence of A/D in this population, FMD patients should be screened for the presence of A/D and offered appropriate treatment. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Pawlik, C., Kline-Rogers, E., Olin, J. W., Gornik, H. L., Mace, P., Gu, X., Swan, K., Krallman, R., Kim, E. S., Wells, B. J., Weinberg, I., Sharma, A. M., Gray, B., Froehlich, J. B. Tags: Session Title: Poster Session AM Source Type: research

Abstract 120: Persistence in Antihypertensive Therapy - The Chicago Heart Association Detection Project Industry Study [Session Title: Poster Session AM]
Conclusion: Adherence to antihypertensive therapy decreased significantly over time and with greater medication burden. Interventions are needed to improve persistence in antihypertensive therapy, particularly among those taking multiple medications. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Schiman, C., Liu, L., Shih, Y.-C. T., Zhao, L., Daviglus, M., Liu, K., Fries, J., Garside, D., Vu, T.-H., Stamler, J., Lloyd-Jones, D., Allen, N. Tags: Session Title: Poster Session AM Source Type: research

Abstract 119: Quality of Life Outcomes in Patients With Known Coronary Artery Disease Presenting With Suspected Ischemia Randomized to Pharmacologic Stress Myocardial Perfusion Imaging With Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) [Session Title: Poster Session AM]
Conclusions: In symptomatic patients with CAD undergoing stress MPI, health status improved significantly over a year of follow-up. Although PET MPI more accurately details the ischemia, use of this imaging modality did not translate into improved health status over time. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Patel, K. K., Al Badarin, F., Arnold, S. V., McGhie, A. I., Kureshi, F., Kennedy, K. F., Courter, S., Spertus, J. A., Bateman, T. M. Tags: Session Title: Poster Session AM Source Type: research

Abstract 118: Factors Associated With Hospital Length of Stay for Heart Failure [Session Title: Poster Session AM]
Conclusion: For Florida inpatients, the mean hospital HF LOS was positively associated with hospital-wide metrics of total staff size, MRSA rate, and time spent in the ED. Since the data were observational and many factors were not controlled, potential causality can not be determined. Further study is needed to discover the mechanisms behind these associations, as well as any potential confounding factors.Disclaimers: Results here were derived from limited data sets of the Florida AHCA. However, Florida AHCA does not claim responsibility for any of the resulting analysis, interpretations or conclusions. The authors and th...
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Zeger, L. M., Williams, J., Haight, D. O. Tags: Session Title: Poster Session AM Source Type: research

Abstract 117: Presence of Mental Health Disorders, Low Socioeconomic Status, More Closely Associated With Adverse Cardiovascular Outcomes After a Recent Hospitalization [Session Title: Poster Session AM]
Conclusions: The presence of MHDs appears to be more strongly associated with negative outcomes than low SES. Efforts to develop and improve interventional care strategies that target patients with MHDs should be made to reduce these health disparities. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Feldeisen, D., Krallman, R., Morgan, S., Montgomery, D., Kline-Rogers, E., Eagle, K. A., Bumpus, S. M. Tags: Session Title: Poster Session AM Source Type: research

Abstract 116: Independent Prognostic Value of Guideline-Directed Medical Therapy, Radial Access, and Door-to-Balloon Time in Predicting STEMI In-Hospital Mortality [Session Title: Poster Session AM]
Conclusions: Prompt GDMT administration, radial access for PCI, and D2BT performance add incremental prognostic value. Expanding STEMI systems of care from a singular focus on D2BT to a comprehensive focus on multi-faceted STEMI care offers an opportunity to further improve STEMI outcomes. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Huded, C., Johnson, M., Ballout, J., Kravitz, K., Menon, V., Abdallah, M., Gullett, T., Hantz, S., Ellis, S., Podoslky, S., Meldon, S., Kralovic, D., Brosovich, D., Smith, E., Kapadia, S., Khot, U. Tags: Session Title: Poster Session AM Source Type: research

Abstract 115: Results of a Twelve Month Randomized Trial of an Internet Based Lifestyle Intervention in High Cardio Metabolic Risk Individuals: The Baptist Employee Healthy Heart Study (BEHHS) [Session Title: Poster Session AM]
Conclusion: The addition of web-based, personalized lifestyle program to an already existing lifestyle educational platform did not significantly impact healthy lifestyle promotion and cardiometabolic risk in employees with MetS or DM2. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Aneni, E., Arias, L., Post, J., Ali, S. S., Osondu, C. U., Saxena, A., Agatston, A. S., Katzen, B., Feldman, T., Nasir, K. Tags: Session Title: Poster Session AM Source Type: research

Abstract 114: Does Size Matter? Comparing Cardiac Arrest Survival to Discharge Rates Based on Number of Hospital Beds [Session Title: Poster Session AM]
Conclusions: Survival to discharge from in-hospital cardiac arrest is not dependent on hospital bed size. It is important that hospitals collect and analyze data regarding in-hospital cardiac arrests to improve survival rates beyond the 24.9% identified in the HEROIC study. A further examination looking at discharge destinations with CPC scores should be considered for a future study. (Source: Circulation: Cardiovascular Quality and Outcomes)
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Thomas, K., Gueret, R., Miller, A., Myers, G. Tags: Session Title: Poster Session AM Source Type: research