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Complete Revascularization in Patients Before Undergoing Transcatheter Aortic Valve Replacement: Desirable or Superfluous? [Editorials]
(Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Shamekhi, J., Sinning, J.-M. Tags: Catheter-Based Coronary and Valvular Interventions Editorials Source Type: research

Is Treatment of ST-Segment-Elevation Myocardial Infarction Patients With Ticagrelor or Other P2Y12 Inhibitors Before Primary Percutaneous Coronary Intervention a Strategy Without Benefit? [Editorials]
(Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Huber, K. Tags: Catheter-Based Coronary and Valvular Interventions, Treatment Editorials Source Type: research

Nitric Oxide Attenuates Arterial Pulse Wave Reflection in a Vasodilator Responding Pulmonary Arterial Hypertension Patient [Case Reports in Interventional Cardiology]
(Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Su, J., Hughes, A. D., Simonsen, U., Howard, L. S. Tags: Hemodynamics, Pathophysiology, Pulmonary Hypertension, Pharmacology Case Reports in Interventional Cardiology Source Type: research

Catheter-Based Measurements of Absolute Coronary Blood Flow and Microvascular Resistance: Feasibility, Safety, and Reproducibility in Humans [Cardiac Catheterization]
Conclusions— Absolute coronary blood flow (in L/min) and R (in mm Hg/L/min or Wood units) can be safely and reproducibly measured with continuous thermodilution. This approach constitutes a new opportunity for the study of the coronary microcirculation. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Xaplanteris, P., Fournier, S., Keulards, D. C. J., Adjedj, J., Ciccarelli, G., Milkas, A., Pellicano, M., vant Veer, M., Barbato, E., Pijls, N. H. J., De Bruyne, B. Tags: Coronary Circulation, Hemodynamics, Physiology Cardiac Catheterization Source Type: research

Incidence, Patterns, and Impact of Dual Antiplatelet Therapy Cessation Among Patients With and Without Chronic Kidney Disease Undergoing Percutaneous Coronary Intervention: Results From the PARIS Registry (Patterns of Non-Adherence to Anti-Platelet Regimens in Stented Patients) [Coronary Interventions]
Conclusions— Patients with CKD display high and comparable risks for both ischemic and bleeding events after PCI. Physicians are more likely to discontinue DAPT within the first year after PCI among patients with CKD, likely reflecting clinical preferences to avoid bleeding. Risks after DAPT cessation, irrespective of underlying mode, are not modified by the presence or absence of CKD. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Baber, U., Li, S. X., Pinnelas, R., Pocock, S. J., Krucoff, M. W., Ariti, C., Gibson, C. M., Steg, P. G., Weisz, G., Witzenbichler, B., Henry, T. D., Kini, A. S., Stuckey, T., Cohen, D. J., Iakovou, I., Dangas, G., Aquino, M. B., Sartori, S., Chieffo, A., Tags: Compliance/Adherence, Percutaneous Coronary Intervention, Pharmacology Coronary Interventions Source Type: research

Impact of Coronary Artery Revascularization Completeness on Outcomes of Patients With Coronary Artery Disease Undergoing Transcatheter Aortic Valve Replacement: A Meta-Analysis of Studies Using the Residual SYNTAX Score (Synergy Between PCI With Taxus and Cardiac Surgery) [Structural Heart Disease]
Conclusions— Our results suggest that for patients with CAD undergoing transcatheter aortic valve replacement, a residual SYNTAX score–guided revascularization strategy may carry significant benefits in terms of mortality. Adequate revascularization may offer a unique and valuable opportunity to improve the prognosis of these patients. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Witberg, G., Zusman, O., Codner, P., Assali, A., Kornowski, R. Tags: Catheter-Based Coronary and Valvular Interventions, Percutaneous Coronary Intervention, Revascularization Structural Heart Disease Source Type: research

Clinical Outcomes and Prognosis Markers of Patients With Liver Disease Undergoing Transcatheter Aortic Valve Replacement: A Propensity Score-Matched Analysis [Structural Heart Disease]
Conclusions— These findings suggested that TAVR is a feasible treatment for severe aortic stenosis in patients with early-stage liver disease or as bridge therapy before a curative treatment of the hepatic condition. Patients with Child-Pugh class B-C, especially in combination with renal impairment, had a very low survival rate, and TAVR should be carefully considered to avoid a futile treatment. These results may contribute to improve the clinical decision-making process and management in patients with liver disease. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Tirado-Conte, G., Rodes-Cabau, J., Rodriguez-Olivares, R., Barbanti, M., Lhermusier, T., Amat-Santos, I., Toggweiler, S., Cheema, A. N., Munoz-Garcia, A. J., Serra, V., Giordana, F., Veiga, G., Jimenez-Quevedo, P., Campelo-Parada, F., Loretz, L., Todaro, Tags: Valvular Heart Disease, Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Mortality/Survival, Quality and Outcomes Structural Heart Disease Source Type: research

Bleeding Severity After Percutaneous Coronary Intervention [Coronary Artery Disease]
Conclusions— Among patients who undergo successful percutaneous coronary intervention, bleeding events that result in Hgb ≥4.0 g/dL are associated with a considerably increased risk of dying. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT00638794. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Redfors, B., Genereux, P., Witzenbichler, B., Kirtane, A. J., McAndrew, T., Weisz, G., Stuckey, T. D., Henry, T. D., Maehara, A., Mehran, R., Stone, G. W. Tags: Percutaneous Coronary Intervention, Stent Coronary Artery Disease Source Type: research

No Benefit of Ticagrelor Pretreatment Compared With Treatment During Percutaneous Coronary Intervention in Patients With ST-Segment-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention [Myocardial Infarction]
Conclusions— Ticagrelor pretreatment versus ticagrelor given in the catheterization laboratory in patients with ST-segment–elevation myocardial infarction undergoing primary PCI did not improve the composite end point of all-cause mortality or MI or stent thrombosis or its individual components at 30 days. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Koul, S., Smith, J. G., Gotberg, M., Omerovic, E., Alfredsson, J., Venetsanos, D., Persson, J., Jensen, J., Lagerqvist, B., Redfors, B., James, S., Erlinge, D. Tags: Anticoagulants, Percutaneous Coronary Intervention, Treatment Myocardial Infarction Source Type: research

The Case for Selective Patent Foramen Ovale Closure After Cryptogenic Stroke [Advances in Interventional Cardiology]
Controversy has persisted for over a decade whether transcatheter patent foramen ovale (PFO) closure reduces the rate of recurrent ischemic stroke for patients who have had a cryptogenic ischemic stroke and have a PFO. In September 2017, 3 positive randomized trials: RESPECT long-term (Recurrent Stroke Comparing PFO Closure to Established Current Standard of Care Treatment trial), REDUCE (GORE® HELEX® Septal Occluder / GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke or Imaging-Confirmed TIA in Patients With Patent Foramen Ovale [PFO]), and CLOSE (Patent For...
Source: Circulation: Cardiovascular Interventions - March 16, 2018 Category: Cardiology Authors: Wiktor, D. M., Carroll, J. D. Tags: Secondary Prevention, Treatment, Ischemic Stroke Advances in Interventional Cardiology Source Type: research

Sex Differences in Long-Term Cause-Specific Mortality After Percutaneous Coronary Intervention: Temporal Trends and Mechanisms [Coronary Interventions]
Conclusions— The higher mortality after percutaneous coronary intervention in women is because of death from noncardiac causes. This is accounted for by baseline age and comorbidities rather than an additional sex-specific factor. These findings have implications for sex-specific clinical care and trial design. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 14, 2018 Category: Cardiology Authors: Raphael, C. E., Singh, M., Bell, M., Crusan, D., Lennon, R. J., Lerman, A., Prasad, A., Rihal, C. S., Gersh, B. J., Gulati, R. Tags: Percutaneous Coronary Intervention Coronary Interventions Source Type: research

Percutaneous Left Atrial Appendage Closure Is a Reasonable Option for Patients With Atrial Fibrillation at High Risk for Cerebrovascular Events [New Techniques]
Conclusions— This nationwide prospective registry shows that, in the French population, LAA closure is mainly used in patients with high comorbidity rates and a poor prognosis. LAA closure in such patients seems reasonable to decrease the stroke rate. The overall health status of these patients should be taken into account during the preprocedural evaluation process. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT02252861. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - March 14, 2018 Category: Cardiology Authors: Teiger, E., Thambo, J.-B., Defaye, P., Hermida, J.-S., Abbey, S., Klug, D., Juliard, J.-M., Pasquie, J.-L., Rioufol, G., Lepillier, A., Elbaz, M., Horvilleur, J., Brenot, P., Pierre, B., Le Corvoisier, P., on behalf of the French National Left Atrial Appe Tags: Arrhythmias, Treatment, Ischemic Stroke New Techniques Source Type: research

What Lies Beneath Left Atrial Appendage Occlusion: Know Your Enemy [Editorials]
(Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - February 20, 2018 Category: Cardiology Authors: Meier, B. Tags: Computerized Tomography (CT), Echocardiography, Catheter-Based Coronary and Valvular Interventions, Ischemic Stroke Editorials Source Type: research

Device Thrombosis After Percutaneous Left Atrial Appendage Occlusion Is Related to Patient and Procedural Characteristics but Not to Duration of Postimplantation Dual Antiplatelet Therapy [Structural Heart Disease]
Conclusions— In this real-world series, DRT was observed early, late, and very late after left atrial appendage occlusion. It was related to patient and procedural characteristics but not to postimplantation dual antiplatelet therapy duration. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - February 20, 2018 Category: Cardiology Authors: Pracon, R., Bangalore, S., Dzielinska, Z., Konka, M., Kepka, C., Kruk, M., Kaczmarska-Dyrda, E., Petryka-Mazurkiewicz, J., Bujak, S., Solecki, M., Pskit, A., Dabrowska, A., Sieradzki, B., Plonski, A., Ruzyllo, W., Witkowski, A., Demkow, M. Tags: Catheter-Based Coronary and Valvular Interventions Structural Heart Disease Source Type: research

Quantitative Flow Ratio Identifies Nonculprit Coronary Lesions Requiring Revascularization in Patients With ST-Segment-Elevation Myocardial Infarction and Multivessel Disease [Cardiac Catheterization]
Conclusions— In a limited and selected study population, our study showed that QFR computation may be a safe and reliable tool to guide coronary revascularization of NCLs in ST-segment–elevation myocardial infarction patients. (Source: Circulation: Cardiovascular Interventions)
Source: Circulation: Cardiovascular Interventions - February 15, 2018 Category: Cardiology Authors: Spitaleri, G., Tebaldi, M., Biscaglia, S., Westra, J., Brugaletta, S., Erriquez, A., Passarini, G., Brieda, A., Leone, A. M., Picchi, A., Ielasi, A., Girolamo, D. D., Trani, C., Ferrari, R., Reiber, J. H. C., Valgimigli, M., Sabate, M., Campo, G. Tags: Catheter-Based Coronary and Valvular Interventions, Stent, Acute Coronary Syndromes, Coronary Artery Disease Cardiac Catheterization Source Type: research