Circulation: Cardiovascular Genetics This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Informational Quest [Editorials]
(Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - August 4, 2017 Category: Cardiology Authors: Haga, S. B. Tags: Genetics Editorials Source Type: research

Towards Point-of-Care Measurements Using Noncoding RNAs: A Novel Tool to Monitor Aggravation of Advanced Atherosclerotic Lesions [Editorials]
(Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - August 4, 2017 Category: Cardiology Authors: Paloschi, V., Maegdefessel, L. Tags: Biomarkers, Functional Genomics, Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke Editorials Source Type: research

Carotid Plaque Rupture Is Accompanied by an Increase in the Ratio of Serum circR-284 to miR-221 Levels [Original Articles]
Conclusions— Serum circR-284:miR-221 has potential as a diagnostic biomarker of carotid plaque rupture and stroke. Moreover, we demonstrate the use of functionally related pairs of circulating noncoding RNAs as biomarkers in cardiovascular disease. (Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - August 4, 2017 Category: Cardiology Authors: Bazan, H. A., Hatfield, S. A., Brug, A., Brooks, A. J., Lightell, D. J., Woods, T. C. Tags: Biomarkers, Functional Genomics, Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Articles Source Type: research

Effect of Disclosing Genetic Risk for Coronary Heart Disease on Information Seeking and Sharing: The MI-GENES Study (Myocardial Infarction Genes) [Original Articles]
Conclusions— Disclosure of a genetic risk score for CHD increased information seeking and sharing. Clinical Trial Registration— URL: https://clinicaltrials.gov/. Unique identifier: NCT01936675. (Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - August 4, 2017 Category: Cardiology Authors: Brown, S.-A. N., Jouni, H., Marroush, T. S., Kullo, I. J. Tags: Clinical Studies, Translational Studies, Cardiovascular Disease, Primary Prevention, Genetics Original Articles Source Type: research

Loss of Chromosome Y in Leukocytes and Major Cardiovascular Events [Editorial]
(Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - August 2, 2017 Category: Cardiology Authors: Dumanski, J. P., Sundstrom, J., Forsberg, L. A. Tags: Inflammation, Cardiovascular Disease, Genetics, Mortality/Survival, Atherosclerosis Editorial Source Type: research

Previously Unreported in Women Galactosidase Alpha Pro409Ser Variant Is Associated With Fabry Disease [Clinical Genomic Cases]
(Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - August 2, 2017 Category: Cardiology Authors: Luis, S. A., Maleszewski, J. J., Young, P. M., Schaff, H. V., Pereira, N. L. Tags: Mechanisms, Pathophysiology, Genetics, Functional Genomics, Cardiomyopathy Clinical Genomic Cases Source Type: research

PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites [Original Articles]
Conclusions— PCSK9 LOF variants were associated with lower LDL-C and coronary heart disease incidence. PCSK9 LOF variants were not associated with stroke risk. (Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - August 2, 2017 Category: Cardiology Authors: Kent, S. T., Rosenson, R. S., Avery, C. L., Chen, Y.-D. I., Correa, A., Cummings, S. R., Cupples, L. A., Cushman, M., Evans, D. S., Gudnason, V., Harris, T. B., Howard, G., Irvin, M. R., Judd, S. E., Jukema, J. W., Lange, L., Levitan, E. B., Li, X., Liu, Tags: Lipids and Cholesterol, Genetic, Association Studies, Myocardial Infarction, Meta Analysis, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Cardiovascular Disease and Long Noncoding RNAs: Tools for Unraveling the Mystery Lnc-ing RNA and Phenotype [Advances in Genetics]
(Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - August 2, 2017 Category: Cardiology Authors: Hennessy, E. J. Tags: Basic Science Research, Cell Biology/Structural Biology, Cell Signaling/Signal Transduction Advances in Genetics Source Type: research

Loss of Y Chromosome in Blood Is Associated With Major Cardiovascular Events During Follow-Up in Men After Carotid Endarterectomy [Original Articles]
Conclusions— In this hypothesis-generating study, LOY in blood is independently associated with secondary major cardiovascular events in a severely atherosclerotic population. Our data could indicate that LOY affects secondary outcome via other mechanisms than inflammation in the atherosclerotic plaque. (Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - August 2, 2017 Category: Cardiology Authors: Haitjema, S., Kofink, D., van Setten, J., van der Laan, S. W., Schoneveld, A. H., Eales, J., Tomaszewski, M., de Jager, S. C. A., Pasterkamp, G., Asselbergs, F. W., den Ruijter, H. M. Tags: Inflammation, Genetics, Mortality/Survival, Atherosclerosis Original Articles Source Type: research

The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association [AHA Scientific Statement]
There have been major advances in our knowledge of the contribution of DNA sequence variations to cardiovascular disease and stroke. However, the inner workings of the body reflect the complex interplay of factors beyond the DNA sequence, including epigenetic modifications, RNA transcripts, proteins, and metabolites, which together can be considered the "expressed genome." The emergence of high-throughput technologies, including epigenomics, transcriptomics, proteomics, and metabolomics, is now making it possible to address the contributions of the expressed genome to cardiovascular disorders. This statement describes how ...
Source: Circulation: Cardiovascular Genetics - July 31, 2017 Category: Cardiology Authors: Musunuru, K., Ingelsson, E., Fornage, M., Liu, P., Murphy, A. M., Newby, L. K., Newton-Cheh, C., Perez, M. V., Voora, D., Woo, D., on behalf of the American Heart Association Committee on Molecular Determinants of Cardiovascular Health of the Council on F Tags: Statements and Guidelines AHA Scientific Statement Source Type: research

Translating Polygenic Analysis for Prevention: From Who to How [Editorial]
(Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - June 15, 2017 Category: Cardiology Authors: Belsky, D. W. Tags: Biomarkers, Epidemiology, Obesity, Genetics Editorial Source Type: research

Genes, Environment, and the Heart: Putting the Pieces Together [Editorial]
(Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - June 15, 2017 Category: Cardiology Authors: Kirk, E. P. Tags: Cardiovascular Disease, Genetic, Association Studies, Genetics Editorial Source Type: research

Translating Polygenic Analysis for Prevention: From Who to How [Editorials]
(Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - June 15, 2017 Category: Cardiology Authors: Belsky, D. W. Tags: Biomarkers, Epidemiology, Obesity, Genetics Editorials Source Type: research

Genes, Environment, and the Heart: Putting the Pieces Together [Editorials]
(Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - June 15, 2017 Category: Cardiology Authors: Kirk, E. P. Tags: Cardiovascular Disease, Genetic, Association Studies, Genetics Editorials Source Type: research

Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals From 124 Cohorts: Design and Rationale [Original Articles]
Conclusions— The Gene-Lifestyle Interactions Working Group provides an excellent framework for understanding the lifestyle context of genetic effects and to identify novel trait loci through analysis of interactions. An important and novel feature of our study is that the gene–lifestyle interaction (GxE) results may improve our knowledge about the underlying mechanisms for novel and already known trait loci. (Source: Circulation: Cardiovascular Genetics)
Source: Circulation: Cardiovascular Genetics - June 15, 2017 Category: Cardiology Authors: Rao, D. C., Sung, Y. J., Winkler, T. W., Schwander, K., Borecki, I., Cupples, L. A., Gauderman, W. J., Rice, K., Munroe, P. B., Psaty, B. M., on behalf of the CHARGE Gene-Lifestyle Interactions Working Group* Tags: Cardiovascular Disease, Lifestyle, Risk Factors, Genetic, Association Studies, Meta Analysis Original Articles Source Type: research