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Tachycardia-Induced J-Wave Changes in Patients With and Without Idiopathic Ventricular Fibrillation [Original Articles]
Conclusions— The response to atrial pacing was different between the IVF and non-IVF patients, which suggests the presence of different mechanisms for the genesis of J waves. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - July 7, 2017 Category: Cardiology Authors: Aizawa, Y., Takatsuki, S., Nishiyama, T., Kimura, T., Kohsaka, S., Kaneko, Y., Inden, Y., Takahashi, N., Nagase, S., Aizawa, Y., Fukuda, K. Tags: Arrhythmias, Electrophysiology, Ventricular Fibrillation Original Articles Source Type: research

Stand-Alone Pulmonary Vein Isolation Versus Pulmonary Vein Isolation With Additional Substrate Modification as Index Ablation Procedures in Patients With Persistent and Long-Standing Persistent Atrial Fibrillation: The Randomized Alster-Lost-AF Trial (Ablation at St. Georg Hospital for Long-Standing Persistent Atrial Fibrillation) [Original Articles]
Conclusions— In patients with persistent and long-standing persistent atrial fibrillation, no significant difference was observed in 12-month freedom from atrial tachyarrhythmias between an index ablative approach of stand-alone PVI and a stepwise approach of PVI plus complex fractionated atrial electrogram and linear ablation. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00820625. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - July 7, 2017 Category: Cardiology Authors: Fink, T., Schluter, M., Heeger, C.-H., Lemes, C., Maurer, T., Reissmann, B., Riedl, J., Rottner, L., Santoro, F., Schmidt, B., Wohlmuth, P., Mathew, S., Sohns, C., Ouyang, F., Metzner, A., Kuck, K.-H. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator Original Articles Source Type: research

Atrioventricular Nodal Reentrant Tachycardia in Patients With Congenital Heart Disease: Outcome After Catheter Ablation [Original Articles]
Conclusions— Atrioventricular nodal reentrant tachycardia can complicate the course of patients with CHD. This study demonstrates that the outcome of catheter ablation is favorable in patients with simple CHD. Patients with complex CHD have increased risk of procedural failure and atrioventricular block. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - July 7, 2017 Category: Cardiology Authors: Papagiannis, J., Beissel, D. J., Krause, U., Cabrera, M., Telishevska, M., Seslar, S., Johnsrude, C., Anderson, C., Tisma-Dupanovic, S., Connelly, D., Avramidis, D., Carter, C., Kornyei, L., Law, I., Von Bergen, N., Janusek, J., Silva, J., Rosenthal, E., Tags: Arrhythmias, Atrial Fibrillation, Congenital Heart Disease Original Articles Source Type: research

Diagnostic Perturbations [Teaching Rounds in Cardiac Electrophysiology]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 19, 2017 Category: Cardiology Authors: Asirvatham, S. J., Stevenson, W. G. Tags: Arrhythmias, Electrophysiology Teaching Rounds in Cardiac Electrophysiology Source Type: research

Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 19, 2017 Category: Cardiology Authors: Li, Y., Sallam, K., Schwartz, P. J., Wu, J. C. Tags: Arrhythmias, Electrophysiology Editorial Source Type: research

Experimental, Pathologic, and Clinical Findings of Radiofrequency Catheter Ablation of Para-Hisian Region From the Right Ventricle in Dogs and Humans [Original Articles]
Conclusions— Differentiating the NF His from far-field His activations led to a high ablation success without atrioventricular block in para-Hisian AP patients. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 19, 2017 Category: Cardiology Authors: Xue, Y., Zhan, X., Wu, S., Wang, H., Liu, Y., Liao, Z., Deng, H., Duan, X., Zeng, S., Liang, D., Elvan, A., Fang, X., Liao, H., Ramdat Misier, A. R., Smit, J. J. J., Metzner, A., Heeger, C.-H., Liu, F., Wang, F., Zhang, Z., Kuck, K.-H., Yen Ho, S., Ouyang Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology Original Articles Source Type: research

Primary Prevention of Sudden Cardiac Death Early Post-Myocardial Infarction: Root Cause Analysis for Implantable Cardioverter-Defibrillator Failure and Currently Available Options [Advances in Arrhythmia and Electrophysiology]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 19, 2017 Category: Cardiology Authors: Elayi, C. S., Charnigo, R. J., Heron, P. M., Lee, B. K., Olgin, J. E. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Sudden Cardiac Death, Ventricular Fibrillation, Meta Analysis Advances in Arrhythmia and Electrophysiology Source Type: research

Role of His Refractory Premature Ventricular Complexes in the Differential Diagnosis of a Left Bundle Branch Block Morphology Tachycardia [Teaching Rounds in Cardiac Electrophysiology]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 19, 2017 Category: Cardiology Authors: Bagga, S., Patel, P. J., Prystowsky, E. N., Padanilam, B. J. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology Teaching Rounds in Cardiac Electrophysiology Source Type: research

Distinctive Left Ventricular Activations Associated With ECG Pattern in Heart Failure Patients [Original Articles]
Conclusions— In contrast to LBBB patients, narrow QRS and NICD patients are characterized by distinct mechanisms of LV activation, which may predict poor response to cardiac resynchronization therapy. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 19, 2017 Category: Cardiology Authors: Derval, N., Duchateau, J., Mahida, S., Eschalier, R., Sacher, F., Lumens, J., Cochet, H., Denis, A., Pillois, X., Yamashita, S., Komatsu, Y., Ploux, S., Amraoui, S., Zemmoura, A., Ritter, P., Hocini, M., Haissaguerre, M., Jais, P., Bordachar, P. Tags: Physiology, Heart Failure Original Articles Source Type: research

Characterization of Aortic Valve Closure Artifact During Outflow Tract Mapping: Correlation With Hemodynamics and Mechanical Valves [Original Articles]
Conclusions— In patients referred for left ventricle outflow tract premature ventricular contraction ablation, an aortic valve closure artifact is observed in up to one third of cases during mapping within the aortic cusps. The timing of this artifact correlates with invasive hemodynamics and mechanical aortic valve artifacts. Recognition of this physiological phenomenon is useful when assigning near-field activation. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 19, 2017 Category: Cardiology Authors: Romero, J., Ajijola, O., Shivkumar, K., Tung, R. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology Original Articles Source Type: research

Patient-Specific Drug Screening Using a Human Induced Pluripotent Stem Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Type 2 [Original Articles]
Conclusions— These results demonstrate the ability of hiPSCs cardiomyocytes to recapitulate CPVT2 disease phenotype and drug response in the culture dish, to provide novel insights into disease and drug therapy mechanisms, and potentially to tailor patient-specific drug therapy. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 19, 2017 Category: Cardiology Authors: Maizels, L., Huber, I., Arbel, G., Tijsen, A. J., Gepstein, A., Khoury, A., Gepstein, L. Tags: Arrhythmias, Sudden Cardiac Death, Calcium Cycling/Excitation-Contraction Coupling, Cellular Reprogramming, Stem Cells Original Articles Source Type: research

Incidence and Factors Associated With the Occurrence of Pulmonary Vein Narrowing After Cryoballoon Ablation [Original Articles]
Conclusions— A reduction of the PVD was often observed after cryoballoon ablation for atrial fibrillation. A larger PV ostium and lower minimum freezing temperature during cryoballoon ablation were associated with an increased risk of PVD reduction. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 19, 2017 Category: Cardiology Authors: Narui, R., Tokuda, M., Matsushima, M., Isogai, R., Tokutake, K., Yokoyama, K., Hioki, M., Ito, K., Tanigawa, S.-i., Yamashita, S., Inada, K., Shibayama, K., Matsuo, S., Miyanaga, S., Sugimoto, K., Yoshimura, M., Yamane, T. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator Original Articles Source Type: research

Modifying Arrhythmia Behavior Preablation With Drug Therapy May Improve Single Procedure Efficacy of a Limited Ablation Strategy in Patients With Persistent Atrial Fibrillation [Editorials]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 13, 2017 Category: Cardiology Authors: Dixit, S., Liang, J. J., Pathak, R. K. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator Editorials Source Type: research

Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the IKs Amplitude in Check Until When Larger IKs Is Needed [Original Articles]
Conclusions— In adult ventricular myocytes, KCNE1 maintains a stable presence on the cell surface, whereas KCNQ1 is dynamic in its localization. KCNQ1 is largely in an intracellular reservoir under basal conditions but can traffic to the cell surface and boost the IKs amplitude in response to stress. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 13, 2017 Category: Cardiology Authors: Jiang, M., Wang, Y., Tseng, G.-N. Tags: Arrhythmias, Electrophysiology, Basic Science Research, Cardiomyopathy, Remodeling Original Articles Source Type: research

Pulmonary Vein Isolation Alone Versus Additional Linear Ablation in Patients With Persistent Atrial Fibrillation Converted to Paroxysmal Type With Antiarrhythmic Drug Therapy: A Multicenter, Prospective, Randomized Study [Original Articles]
Conclusions— CPVI alone is an effective rhythm control strategy with a shorter procedure time in persistent AF patients converted to paroxysmal AF compared with CPVI with linear ablation. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT02176616. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - June 13, 2017 Category: Cardiology Authors: Yu, H. T., Shim, J., Park, J., Kim, I.-S., Kim, T.-H., Uhm, J.-S., Joung, B., Lee, M.-H., Kim, Y.-H., Pak, H.-N. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator Original Articles Source Type: research