Pulmonary Mucinous Adenocarcinoma Combined with Bronchial Squamous Cell
Papilloma and Infection with Tropheryma Whipplei: A Case Report
Simultaneous multiple primary tumors on the same side of the lung with Tropheryma whipplei (TW) infection are rare. We reviewed the clinical data, imaging manifestations, pathological results, diagnosis and treatment of a primary pulmonary mucinous adenocarcinoma (PPMA) patient with bronchial squamous cell papilloma (BSCP) and TW infection, and discussed our treatment experience. The patient mainly presented with chronic cough and sputum, and computed tomography (CT) showed inflammatory changes with multiple nodular shadows. Biopsy of the lower lobe of the right lung showed PPMA, and right lung sub-branchial nodules discov...
Source: Chinese Journal of Lung Cancer - July 20, 2023 Category: Cancer & Oncology Source Type: research
Secondary or Second Primary Endotracheal Cancer after Surgery for Primary Lung Cancer: Case Series and Review of the Literature
Conclusion More attention should be paid to the abnormality of the trachea after surgery of lung cancer. CCRT may be a good choice for endot racheal cancers after primary lung cancer.
DOI: 10.3779/j.issn.1009-3419.2023.101.20 (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - July 20, 2023 Category: Cancer & Oncology Source Type: research
Expression of MEF2D in Lung Adenocarcinoma and Its Correlation with Prognosis
Background and objective Myocyte enhancer factor 2D (MEF2D) can participate in the process of tumor lesions by regulating the transcription of oncogenes. In a previous study, MEF2D was demonstrated to enhance the proliferation and metastasis of lung adenocarcinoma cells A549 and H1299 by promoting the transcription of NUSAP1. The research aimed to explore the expression level and clinical significance of MEF2D in lung adenocarcinoma. Methods A total of 199 patients with lung adenocarcinoma were collected. Immunohistochemical staining was used to detect MEF2D expression levels in cancer and adjacent tissues. After the clini...
Source: Chinese Journal of Lung Cancer - July 20, 2023 Category: Cancer & Oncology Source Type: research
Exploration of the Perturbation of PKIG in Lung Squamous Cell Carcinoma and the Role in Tumor Microenvironment Based on Bioinformatics Method
Background and objective Lung cancer is the leading cause of cancer-related death worldwide, and patients have limited survival benefits from traditional treatments such as surgery, radiotherapy and chemotherapy. As a new treatment for lung cancer, immunotherapy has significantly prolonged the overall survival (OS) of patients. However, only some patients can benefit from it. We need to explore immunotherapy biomarkers more deeply to screen for advantages. Methods The original data were downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) database, and the immunological and prognostic genes of l...
Source: Chinese Journal of Lung Cancer - July 20, 2023 Category: Cancer & Oncology Source Type: research
Application Value of Artificial Intelligence-assisted Three-dimensional Reconstruction in Planning Thoracoscopic Segmentectomy
Conclusion It is accurate and safe to use artificial intelligence 3D reconstruction to assist planning thoracoscopic segmentectomy.
DOI: 10.3779/j.issn.1009-3419.2023.102.28 (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - July 20, 2023 Category: Cancer & Oncology Source Type: research
Risk Factors and Sampling Range Evaluation of Lymph node Metastasis for
Non-small Cell Lung Cancer with Diameter ≤2 cm
This study aims to analyze the risk factors and evaluate mediastinal lymph node metastasis sites in different lung lobes for NSCLC with diameter ≤2 cm, so as to provide reference for surgery. Methods We collected 1051 patients with pulmonary nodule diameter ≤2 cm who were treated by pulmonary lobectomy with lymph node sampling/dissection in Department of Thoracic Surgery of the First Affiliated Hospital with Nanjing Medical University fr om December 2009 to December 2019. SPSS 26.0 statistical software was used for statistical analysis, to explore the risk factors and evaluate mediastinal lymph node metastasis sites in...
Source: Chinese Journal of Lung Cancer - July 20, 2023 Category: Cancer & Oncology Source Type: research
A Prognostic Model of Elderly Patients with Non-small Cell Lung Cancer
Based on Geriatric Nutritional Risk Index
Background and objective The relationship between nutritional status and prognosis of cancer patients has emerged as a hotspot for research. The aim of this study is to explore the application value of the geriatric nutritional risk index (GNRI) in assessing the prognosis of elderly patients with non-small cell lung cancer (NSCLC), and establish a Nomogram to predict the prognosis of elderly patients with NSCLC. Methods The data of patients with NSCLC aged ≥65 years who were initially treated in the First Affiliated Hospital of Zhengzhou University from January 2016 to December 2019 were retrospectively analyzed. To dete...
Source: Chinese Journal of Lung Cancer - July 20, 2023 Category: Cancer & Oncology Source Type: research
Development and Validation of A Prognostic Nomogram to Guide Decision-making
in Lung Large Cell Neuroendocrine Carcinoma
Background and objective Lung large cell neuroendocrine carcinoma (LCNEC) is a rare and highly malignant lung tumor with a poor prognosis. Currently, most research on LCNEC is based on retrospective studies and lacks validation in the real world. The study aims to identify independent risk factors and establish and validate a predictive model for the prognosis of LCNEC. Methods Patient data were extracted from Surveillance, Epidemiology, and End Results (SEER) and our department ' s hospitalization records from 2010 to 2015 and 2016 to 2020, respectively. Kaplan-Meier analysis was used to evaluate overall survival (OS). OS...
Source: Chinese Journal of Lung Cancer - July 20, 2023 Category: Cancer & Oncology Source Type: research
Research Progress of Klotho in Lung Neoplasms
This article summarizes the research progress of the role of Klotho on pathogenesis, therapeutic effect and prognosis in lung cancer, in order to provide new biomarker and target for diagnosis, treatment and prognosis of lung cancer.
DOI: 10.3779/j.issn.1009-3419.2023.101.19 (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - June 20, 2023 Category: Cancer & Oncology Source Type: research
Research Progress on the Protective Effect of Intestinal Flora on
Radiation-induced Lung Injury in Thoracic Tumors
Radiation therapy is one of the main treatment methods for patients with thoracic malignant tumors, which can effectively improve the survival rate of the patients. However, radiation therapy can also cause damage to normal tissues while treating tumors, leading to radiation-induced lung injury such as radiation pneumonia and pulmonary fibrosis. Radiation-induced lung injury is a complex pathophysiological process involving many factors, and its prevention and treatment is one of the difficult problems in the field of radiation medicine. Therefore, the search for sensitive predictors of radiation-induced lung injury can gu...
Source: Chinese Journal of Lung Cancer - June 20, 2023 Category: Cancer & Oncology Source Type: research
Retraction of " Altered Treg and IL-1A Expression in the Immune Microenvironment of Lung Squamous-cell Cancer after EGFR Blockade. Zhongguo Feiai Zazhi, 2017, 20(3): 143-148. "
The article titled “Altered Treg and IL-1A Expression in the Immune Microenvironment of Lung Squamous-cell Cancer after EGFR Blockade” (doi: 10.3779/j.issn.1009-3419.2017.03.01) plagiarized the previously published article. Now Editorial Office of Chinese Journal of Lung Cancer has decided to retract it. The edito rial office will strengthen checking procedures for the academic publishing specification to avoid the recurrence of such events in future. DOI: 10.3779/j.issn.1009-3419.2023.102.21 (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - June 20, 2023 Category: Cancer & Oncology Source Type: research
Role of Adverse Events Supervision in Clinical Trials in Neoadjuvant Treatment of
Operable Stage III NSCLC
This study aims to explore the impact of adverse events (AEs) supervision on reducing treatment-related AEs in patients. Methods 66 NSCLC patients admitted to Shanghai Chest Hospital from July 2020 to October 2021 were prospectively collected. All the patients received 3 cycles of neoadjuvant treatment of Camrelizumab in combination with Docetaxel and Cisplatin. 4 weeks-6 weeks after neoadjuvant therapy, the patients accepted surgical treatment. One cycle of postoperative adjuvant treatment was given within 30 days after surgery, and 3 weeks after the completion of postoperative adjuvant treatment, Camrelizumab consolidati...
Source: Chinese Journal of Lung Cancer - June 20, 2023 Category: Cancer & Oncology Source Type: research
CTCs Detection and Whole-exome Sequencing Might Be Used to Differentiate Benign and Malignant Pulmonary Nodules
Conclusion CTCs play an ancillary role in the diagnosis of pulmonary nodules. TP53 mutations in CTCs might be used to identify benign and malignant pulmonary nodules. DOI: 10.3779/j.issn.1009-3419.2023.106.12 (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - June 20, 2023 Category: Cancer & Oncology Source Type: research
Incidence and Risk Factors of Venous Thromboembolism in Patients
with Lung Adenocarcinoma Receiving Anti-tumor Therapy
Background and objective Venous thromboembolism (VTE) as the most common cancer-associated complication has become the second death-causing reason among cancer patients. The management of VTE in patients with lung adenocarcinoma should focus on early and timely detection of risk factors. The aim of the study is to investigate the current situation of VTE in patients with lung adenocarcinoma treated with anti-tumor therapy and then explore the risk factors associated with the occurrence of VTE during anti-tumor therapy for early detection and screening of VTE. Methods The present study included patients diagnosed as lung ad...
Source: Chinese Journal of Lung Cancer - June 20, 2023 Category: Cancer & Oncology Source Type: research
Effect of Different Antitumor Regimens on Incidence and Severity of Corona Virus
Disease 2019 Pneumonia in Lung Cancer Patients:
A Single-center Retrospective Study
Conclusion Intrapulmonary focal radiation therapy within 6 months increased the incidence of COVID-19 pneumonia, but did not increase the severity. However, there was no safety concern for chemotherapy, targeted therapy, surgery and immunotherapy.
DOI: 10.3779/j.issn.1009-3419.2023.102.20 (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - June 20, 2023 Category: Cancer & Oncology Source Type: research
