Chinese Journal of Analytical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Cu2+-mediated Fluorescence Switching of Graphene Quantum Dots for Highly Selective Detection of Glutathione
Publication date: March 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 3Author(s): Xin-Yu LI, Qiang ZHANG, Ni WANG, Jia-Jun LIU, Jian WANG (Source: Chinese Journal of Analytical Chemistry)
Source: Chinese Journal of Analytical Chemistry - March 10, 2020 Category: Chemistry Source Type: research

Molecularly Imprinted Photoelectrochemical Sensor Based on AgBiS2/Bi2S3 for Determination of Propoxur
Publication date: March 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 3Author(s): Xiao-Xue SHI, Xiu-Qi LI, Xiao-Ping WEI, Jian-Ping LI (Source: Chinese Journal of Analytical Chemistry)
Source: Chinese Journal of Analytical Chemistry - March 10, 2020 Category: Chemistry Source Type: research

A Novel Electrochemical Sensor Based on Au-Dy2(WO4)3 Nanocomposites for Simultaneous Determination of Uric Acid and Nitrite
Publication date: March 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 3Author(s): Yu-Mei ZHANG, Hai-Ping HUANG, Liang XU (Source: Chinese Journal of Analytical Chemistry)
Source: Chinese Journal of Analytical Chemistry - March 10, 2020 Category: Chemistry Source Type: research

Cu(II) Metal-Organic Framework Encapsulated in Carbon Paste Electrode for High-Performance Non-Enzymatic Glucose Sensing
Publication date: March 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 3Author(s): Lan WU, Zhi-Wei LU, Ying MA, Jun-Jun ZHANG, Guang-Quan MO, Hai-Jun DU, Jian-Shan YE (Source: Chinese Journal of Analytical Chemistry)
Source: Chinese Journal of Analytical Chemistry - March 10, 2020 Category: Chemistry Source Type: research

Progress on Applications of G-quadruplex in Biochemical Analysis
This article introduces the classification and function of G-quadruplex, and its application in small molecule, protein, enzyme, metal ion, target DNA/RNA detection, cell imaging and cancer therapy. (Source: Chinese Journal of Analytical Chemistry)
Source: Chinese Journal of Analytical Chemistry - February 6, 2020 Category: Chemistry Source Type: research

Advances in Fabrication of Polydiacetylene Vesicles and Their Applications in Medical Detection
Publication date: February 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 2Author(s): Yu-Jia HAO, Guang-Ming ZHUAbstractPolydiacetylenes (PDAs) have received increasing attention as smart materials owing to their unique optical and electronic properties. PDAs are most commonly synthesized as self-assembled bilayer vesicles via 1,4 addition polymerization. Vesicles are often perceived as closely mimicking the cell membrane, thus functioning as convenient biomimetic platforms. PDAs undergo colorimetric and fluorescent transition in response to external stimuli. Therefore, PDA vesicles can be used in th...
Source: Chinese Journal of Analytical Chemistry - February 6, 2020 Category: Chemistry Source Type: research

Study on Drug Resistance to Tumor Cell in Oxygen Gradient and Co-culture Microfluidic Chip
Publication date: February 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 2Author(s): Wei SUN, Yu-Qing CHEN, Ming-Fang WANG, Yue-Rong WANG, Min ZHANG, Hong-Yang ZHANG, Ping HUAbstractThe tumor microenvironment is a complex system that plays a vital role in proliferation, invasion and metastasis. In this work, an oxygen concentration gradient microfluidic chip was designed to construct an in vitro model of tumor hypoxic microenvironment. The microfluidic chip was composed of two parts, one was a serpentine-shape channel for hypoxia reagent mix to generate oxygen gradient, the other part contained thre...
Source: Chinese Journal of Analytical Chemistry - February 6, 2020 Category: Chemistry Source Type: research

Label-free Quantitative Proteomics for Investigation of Signaling Pathways of GATA6 Regulating Trastuzumab Resistance in Gastric Cancer Cells
In this study, Crispr/Cas9 was employed to establish a GATA6 knock-out cell line (NCI N87R/GATA6). The signaling pathways regulated by GATA6 and related to trastuzumab resistance were investigated based on label-free quantitative proteomics combined with bioinformatics. The extracted proteins were alkylated, and digested using filter aided sample preparation (FASP), and the peptides were separated via high performance liquid chromatography (HPLC) and thereafter quantified by liquid chromatography coupled with tandem mass spectroscopy (LC-MS/MS). Differentially expressed proteins were screened by fold change and student's t...
Source: Chinese Journal of Analytical Chemistry - February 6, 2020 Category: Chemistry Source Type: research

Construction of Protein-mediated Copper Sulfide Bonded Mesoporous Silica Nanoparticles Vector for Chemo-photothermal Synergistic Therapy of Cancer
Publication date: February 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 2Author(s): Ruo-Xi HE, Qi WANG, Bei LI, Jing JIA, Wen-Jing LU, Shao-Min SHUANGAbstractBovine serum albumin-mediated copper sulfide nanocomplex (BSA/CuS) was modified on the mesoporous silica (MSN) loaded with chemotherapeutic drug doxorubicin (DOX) by amide bond to prepare a new drug carrier MSN-DOX@BSA/CuS. The disulfide bond of blocking agent BSA broke down after the redox reaction with glutathione, resulting in the MSN pore exposure and release of DOX. As a photothermal reagent, CuS could convert light energy into heat for p...
Source: Chinese Journal of Analytical Chemistry - February 6, 2020 Category: Chemistry Source Type: research

Effect of Wood Vinegar on Adsorption and Desorption of Four Kinds of Heavy (loid) Metals Adsorbents
This study not only provided an effective guidance for rational management of environmental safety, but paved a new path to modify the structure of adsorbents for better adsorption capacities for HMLs Pb(II), Cd(II) and As(III) addition of WV. (Source: Chinese Journal of Analytical Chemistry)
Source: Chinese Journal of Analytical Chemistry - February 6, 2020 Category: Chemistry Source Type: research

Recent Advances in Electrochemiluminescence of Halide Perovskites
Publication date: February 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 2Author(s): Yi KONG, Bao-Hua ZHANG, Zi-Hui ZENG, Yu-Wei ZHANG, Li NIUAbstractNoticeably, halide perovskites have attracted persistent research interest in various fields due to their peculiar merits, e.g. low cost, high mobility, high photoluminescence (PL) quantum yields close to 100%, and excellent color purity and adjustability etc. Very recently, some pioneers evaluated the possibility of perovskite electrochemiluminescence (ECL), with remarkably high ECL intensity and some unique characteristics. Especially, on the basis o...
Source: Chinese Journal of Analytical Chemistry - February 6, 2020 Category: Chemistry Source Type: research

Enrichment Reporter System of Genome Editing Positive Cells
This article summarized the design principles and applications of these reporter systems and would provide a reference to construct a more perfecte evaluating system for genome editing.Graphical abstractCo-transfection of genome editing tool plasmid and reporter vector into cells can represent the positive ratio of genome editing cells by expressing functional proteins with the shift of open reading frame induced by the mechanism of genome repair. The following methods with FACS or resistance selection can effectively enrich the positive cells. Eventually, mutation analysis can be done by T7E1 assay or sequencing. (Source:...
Source: Chinese Journal of Analytical Chemistry - January 11, 2020 Category: Chemistry Source Type: research

Progress in Monolithic Column-based Separation and Enrichment of Glycoproteins
Publication date: January 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 1Author(s): Xue WEN, Hai-Jiao ZHENG, Yang ZHANG, Qiong JIAAbstractAs a post-translational modification, protein glycosylation not only reflects on body health, but also serves as the target of drug treatment. Therefore, it is of great significance to study protein glycosylation for the diagnosis and treatment of diseases. However, many glycoproteins of biological importance exhibit relatively low abundance, high complexity, and wide dynamic range in biological samples. It is indispensable to explore highly efficient sample pretr...
Source: Chinese Journal of Analytical Chemistry - January 11, 2020 Category: Chemistry Source Type: research

A Vacuum Ultraviolet Photoionization Time-of-Flight Mass Spectrometer for Investigation of Free Radical Reaction
Publication date: January 2020Source: Chinese Journal of Analytical Chemistry, Volume 48, Issue 1Author(s): Tao WANG, Xiao-Feng TANG, Zuo-Ying WEN, Cui-Hong ZHANG, Wei-Jun ZHANGAbstractA home-made vacuum ultraviolet (VUV) photoionization linear time-of-flight mass spectrometer (VUVPI-LTOFMS) was utilized to study atmospheric radical reactions. A commercial krypton discharge lamp with photon energy at 10.6 eV was installed as VUV light source and combined with a cage-shape photoionization source to efficiently extract and focus ions. A limit of detection (LOD) of 0.03 μg/L (S/N = 3) for benzene was achieved. A microwave di...
Source: Chinese Journal of Analytical Chemistry - January 11, 2020 Category: Chemistry Source Type: research

Separation and Purification of Sialylglycopeptide from Egg Yolk Based on Cotton Hydrophilic Chromatography
In this study, a simple and low-cost method for the separation and purification of sialylglycopeptide from egg yolk was developed based on hydrophilic interaction chromatography with medical absorbent cotton as stationary phase. Fifty egg yolks were treated with phenol to obtain the crude sialylglycopeptide. The latter was then formulated into a 150 mg/mL solution and loaded on a cotton hydrophilic chromatographic column, followed by treatment with 100%, 95%, 85% and 75% acetonitrile (ACN) aqueous solution to remove impurities. Finally, deionized water was applied for the final elution step. By this way, 300 mg of sialylgl...
Source: Chinese Journal of Analytical Chemistry - January 11, 2020 Category: Chemistry Source Type: research