In vivo investigation of antimicrobial effects of cinnamaldehyde using immunosuppressed ICR mice with invasive pulmonary aspergillosis
ConclusionCinnamaldehyde has a significant influence on the integrity of 1,3-β-D-glucans in the pulmonary A. fumigatus cell wall, but the cell membrane is unaffected, suggesting that cinnamaldehyde has unique antifungal properties depending on its action against the 1,3-β-D-glucans on the pulmonary A. fumigatus cell wall. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - September 25, 2019 Category: Complementary Medicine Source Type: research
A phytochemical study on Dichocarpum auriculatum, an endangered medicinal plant peculiar to China
ConclusionCompound 13 is a new diester terephthalate derivative. All the compounds are obtained from the genus Dichocarpum for the first time, and compounds 9 and 10 have potential chemotaxonomic significance to the genus Dichocarpum. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - September 23, 2019 Category: Complementary Medicine Source Type: research
Synergistic effect of α-mangostin on antibacterial activity of tetracycline, erythromycin, and clindamycin against acne involved bacteria
ConclusionThese findings suggested that α-mangostin may be used to enhance the antibacterial activity of some antibiotics against bacteria involved in acne production. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - September 22, 2019 Category: Complementary Medicine Source Type: research
Monosaccharide analysis and fingerprinting identification of polysaccharides from Poria cocos and Polyporus umbellatus by HPLC combined with chemometrics methods
Conclusion: The fingerprint analysis method of monosaccharide composition of water-soluble polysaccharides can distinguish Poria cocos and Polyporus umbellatus, and can be applied for the authentication or quality control for Poria cocos and Polyporus umbellatus. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - September 18, 2019 Category: Complementary Medicine Source Type: research
In vitro anti-Helicobacter pylori activity of aqueous extract from Persian Oak testa
ConclusionTesta extract is suggested as a natural therapeutic source against the gastric H. pylori infection. However, evaluating the in vivo activity of this extract is necessary too. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - September 17, 2019 Category: Complementary Medicine Source Type: research
Dendrobium orchid polysaccharide extract: Preparation, characterization and in vivo skin hydrating efficacy
ConclusionWhite Dendrobium is ready to be supplied as a specialty ingredient with a safe and efficient profile for skin dryness therapy. This innovative application of the identified traditional Chinese medicinal herb flows in the main stream of the consumers’ preferences and demand upon natural derived products. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - September 12, 2019 Category: Complementary Medicine Source Type: research
Chemical constituents from heartwoods of Caesalpinia sappan with antiplatelet aggregation activities
ConclusionAntiplatelet compounds from C. sappan targeting at PAR4 are reported for the first time. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - September 11, 2019 Category: Complementary Medicine Source Type: research
Boost anti-oxidant activity of yogurt with extract and hydrolysate of cinnamon residues
ConclusionThis study suggested that the anti-oxidant activity of the cinnamon yogurt was influenced by complex protein-phenolic interactions. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - September 9, 2019 Category: Complementary Medicine Source Type: research
Prediction of quality markers of traditional Chinese medicines based on network pharmacology
Publication date: Available online 2 September 2019Source: Chinese Herbal MedicinesAuthor(s): Yu-li Wang, Tao Cui, Ya-zhuo Li, Mao-liang Liao, Hong-bing Zhang, Wen-bin Hou, Tie-jun Zhang, Liang Liu, He Huang, Chang-xiao LiuAbstractNetwork pharmacology is a powerful tool to reflect the pharmacologically active effects, mechanism of action and toxic activity of traditional Chinese medicines (TCMs). The ingredients of TCMs, associated with quality control of TCM products, are those fundamental chemicals that exhibit biological activities. A great amount of effort has been made by scientists in that field in order to improve t...
Source: Chinese Herbal Medicines - September 3, 2019 Category: Complementary Medicine Source Type: research
Network toxicology and LC-MS-based metabolomics: New approaches for mechanism of action of toxic components in traditional Chinese medicines
In this study, we reviewed the application of network toxicology based on LC-MS metabolomics, mainly in the study of toxic components and the toxicity mechanism of TCMs, which provides new ideas and methods for the further study of the toxicity mechanism of TCMs. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - August 30, 2019 Category: Complementary Medicine Source Type: research
Hypoglycemic and antioxidant activities of Clerodendrum inerme leaf extract on streptozotocin-induced diabetic models in mice
ConclusionThese findings suggested that C. inerme leaves have potent antidiabetic and anti-oxidant activities. The results provide reliable scientific base, which is the premise for further research and development of CILE as supplements. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - August 19, 2019 Category: Complementary Medicine Source Type: research
Selection of quality markers of Jasminum amplexicaule based on its anti-diarrheal and anti-inflammatory activities: Effect-target affiliation-traceability-pharmacokinetics strategy
ConclusionsThe present study accurately and effectively identified QMs of J. amplexicaule that act as indicators of efficacy and quality. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - August 19, 2019 Category: Complementary Medicine Source Type: research
An important mechanism of herb-induced hepatotoxicity: To produce RMs based on active functional groups-containing ingredients from phytomedicine by binding CYP450s
Publication date: Available online 9 July 2019Source: Chinese Herbal MedicinesAuthor(s): Xin He, Zi-jun Wu, Li-li Wang, Xue Gao, Yue Hai, Wen-li Liu, Le-mei Du, Lei Zhang, Ai-hong Yang, Nan-nan HuangAbstractReactive metabolites (RMs) generated by hepatic metabolism are thought to play an important role in the pathogenesis of drug-induced liver injury (DILI). Like many synthetic drugs undergoing metabolic activation to form RMs which are often associated with drug toxicity, it is recognized that some herbal components may be also converted to toxic, or even mutagenetic and carcinogenic metabolites by cytochrome P450s (CYP45...
Source: Chinese Herbal Medicines - July 10, 2019 Category: Complementary Medicine Source Type: research
Building a bridge between ecology and Chinese herbal medicines
Publication date: Available online 9 July 2019Source: Chinese Herbal MedicinesAuthor(s): Rui Fang, George He (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - July 9, 2019 Category: Complementary Medicine Source Type: research
Comparative pharmacokinetics of naringin and neohesperidin after oral administration of flavonoid glycosides from Aurantii Fructus Immaturus in normal and gastrointestinal motility disorders mice
ConclusionThe results showed that there were significant differences in pharmacokinetic parameters of naringenin and hesperitin between normal and GMD groups. It was suggested that the absorption of naringenin and hesperitin was increased, and the elimination processes of naringenin and hesperitin were slower in the GMD group than the normal group. The data are of value for further pharmacological studies of ZSTFG and would be useful to provide a reference for improving the therapeutic regimen of ZSTFG in clinical trials. (Source: Chinese Herbal Medicines)
Source: Chinese Herbal Medicines - June 21, 2019 Category: Complementary Medicine Source Type: research
