Smartphone-Based Sensing of Cortisol by Functionalized Rhodamine Probes
Chemistry. 2024 Apr 10:e202401201. doi: 10.1002/chem.202401201. Online ahead of print.ABSTRACTDuring a stress condition, the human body synthesizes catecholamine neurotransmitters and specific hormones (called "stress hormones"), the most important of which is cortisol. The monitoring of cortisol levels should be extremely important to control the stress levels, and for this reason, it shows important medical applications. The common analytical methods (HPLC, GC-MS) cannot be used in real life, due to the bulky size of the instruments and the necessity of specialized personnel. Molecular probes solve these problems due to ...
Source: Chemistry - April 11, 2024 Category: Chemistry Authors: Rossella Santonocito Alessia Cavallaro Roberta Puglisi Andrea Pappalardo Nunzio Tuccitto Manuel Petroselli Giuseppe Trusso Sfrazzetto Source Type: research
Theoretical Study of the Ternary Compound Monolayer CuP2Se for Photocatalytic Water Splitting with Efficient Optical Absorption
Chemistry. 2024 Apr 11:e202400348. doi: 10.1002/chem.202400348. Online ahead of print.ABSTRACTUtilizing photocatalytic method to produce hydrogen by splitting water is an efficient strategy to solve the hotspot issues of energy crisis and environmental pollution. Herein, we systematically investigate the corresponding properties of the reported Cu-bearing ternary compound monolayer CuP2Se by using the first-principle calculations. The monolayer CuP2Se has quite small cleavage energy of 0.51 J/m2, indicating it can be easily produced by the mechanical exfoliation method experimentally. In addition, it is an indirect bandgap...
Source: Chemistry - April 11, 2024 Category: Chemistry Authors: Xiaole Qiu Xiaoxuan Wang Xiaolu Liu Saifei Yuan Kai Han Hongchao Yang Source Type: research
Elucidating the Binding Mode of Sulfur- and Selenium-Based Cationic Chalcogen-Bond Donors
Chemistry. 2024 Apr 11:e202400608. doi: 10.1002/chem.202400608. Online ahead of print.ABSTRACTFor a comparison of the interaction modes of various chalcogen-bond donors, 2-chalcogeno-imidazolium salts have been designed, synthesized, and studied by single crystal X-ray diffraction, solution NMR and DFT as well as for their ability to act as activators in an SN1-type substitution reaction. Their interaction modes in solution were elucidated based on NMR diffusion and chemical shift perturbation experiments, which were supported by DFT-calculations. Our finding is that going from lighter to the heavier chalcogens, hydrogen b...
Source: Chemistry - April 11, 2024 Category: Chemistry Authors: Sercan Akbaba Tim Steinke Lukas Vogel Elric Engelage Mate Erdelyi Stefan Matthias Huber Source Type: research
Smartphone-Based Sensing of Cortisol by Functionalized Rhodamine Probes
Chemistry. 2024 Apr 10:e202401201. doi: 10.1002/chem.202401201. Online ahead of print.ABSTRACTDuring a stress condition, the human body synthesizes catecholamine neurotransmitters and specific hormones (called "stress hormones"), the most important of which is cortisol. The monitoring of cortisol levels should be extremely important to control the stress levels, and for this reason, it shows important medical applications. The common analytical methods (HPLC, GC-MS) cannot be used in real life, due to the bulky size of the instruments and the necessity of specialized personnel. Molecular probes solve these problems due to ...
Source: Chemistry - April 11, 2024 Category: Chemistry Authors: Rossella Santonocito Alessia Cavallaro Roberta Puglisi Andrea Pappalardo Nunzio Tuccitto Manuel Petroselli Giuseppe Trusso Sfrazzetto Source Type: research
Theoretical Study of the Ternary Compound Monolayer CuP2Se for Photocatalytic Water Splitting with Efficient Optical Absorption
Chemistry. 2024 Apr 11:e202400348. doi: 10.1002/chem.202400348. Online ahead of print.ABSTRACTUtilizing photocatalytic method to produce hydrogen by splitting water is an efficient strategy to solve the hotspot issues of energy crisis and environmental pollution. Herein, we systematically investigate the corresponding properties of the reported Cu-bearing ternary compound monolayer CuP2Se by using the first-principle calculations. The monolayer CuP2Se has quite small cleavage energy of 0.51 J/m2, indicating it can be easily produced by the mechanical exfoliation method experimentally. In addition, it is an indirect bandgap...
Source: Chemistry - April 11, 2024 Category: Chemistry Authors: Xiaole Qiu Xiaoxuan Wang Xiaolu Liu Saifei Yuan Kai Han Hongchao Yang Source Type: research
Combined Covalent and Supramolecular Polymerization To Reinforce Perylenebisimide Photosynthetic "Quantasomes"
Chemistry. 2024 Apr 10:e202401061. doi: 10.1002/chem.202401061. Online ahead of print.ABSTRACTInvited for the cover of this issue are the groups of Marcella Bonchio at the University of Padova and Jérôme Canivet at the CNRS-University of Lyon. The image depicts the hierarchical self-organization of bio-inspired quantasomes, crosslinked within a polystyrene network to enchain their lateral and orthogonal proximity for long-lasting oxygen evolution using green photons. Read the full text of the article at 10.1002/chem.202303784.PMID:38595065 | DOI:10.1002/chem.202401061 (Source: Chemistry)
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Alisa Ranscht Francesco Rigodanza Thomas Gobbato Ilaria Crea Elsje Alessandra Quadrelli Jerome Canivet Marcella Bonchio Source Type: research
Chemoselective Post-Synthesis Modification of Pyridyl-Substituted, Aromatic Phosphorus Heterocycles: Cationic Ligands for Coordination Chemistry
Chemistry. 2024 Apr 10:e202400592. doi: 10.1002/chem.202400592. Online ahead of print.ABSTRACTTriazaphospholes are potential polydentate ligands due to the presence of both phosphorus and nitrogen donor atoms within the aromatic 5-membered heterocycle. The incorporation of an additional pyridyl-substituent opens up the possibility of a post-synthesis modification via chemoselective and also stepwise alkylation exclusively of the nitrogen atoms. This can be controlled by the choice and by the stoichiometry of the electrophile and allows the targeted synthesis of a variety of novel mono- and dicationic ligands. Reaction with...
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Lea Dettling Martin Papke Moritz Ernst Manuela Weber Christian M üller Source Type: research
Improving the Stability and Kinetic Inertness of Mn(II) Complexes by Increasing the Bridge Length in Bicyclic CDTA-like Ligands
Chemistry. 2024 Apr 10:e202400570. doi: 10.1002/chem.202400570. Online ahead of print.ABSTRACTKinetic inertness of Mn(II)-based MRI contrast agents can be improved by increasing the rigidity of the polydentate ligand that tightly coordinate the metal ion. Taking inspiration from the remarkable increase in kinetic inertness of [Mn(CDTA)]2- compared to [Mn(EDTA)]2- due to the cyclohexyl backbone rigidity, we devised that bicyclic ligands would further improve the kinetic inertness of the Mn(II) complexes. The length of the alkyl bridge on the cyclohexane ring was varied from methylene (BCH-DTA), ethylene (BCO-DTA) to propyle...
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Jonathan Martinelli Elisabetta Romano Attila Laczovics David Horv áth Elena Grattoni Zsolt Baranyai Lorenzo Tei Source Type: research
Host-Guest Stimuli-Responsive Click Chemistry
Chemistry. 2024 Apr 10:e202400743. doi: 10.1002/chem.202400743. Online ahead of print.ABSTRACTClick chemistry has reached its maturity as the weapon of choice for the irreversible ligation of molecular fragments, with over 20 years of research resulting in the development or improvement of highly efficient kinetically controlled conjugation reactions. Nevertheless, traditional click reactions can be disadvantageous not only in terms of efficiency (side products, slow kinetics, air/water tolerance, etc.), but also because they completely avoid the possibility to reversibly produce and control bound/unbound states. Recently,...
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Arturo Blanco-G ómez Mauro D íaz-Abellás Iv án Montes de Oca Carlos Peinador Elena Pazos Marcos D Garc ía Source Type: research
On the Synthesis and Structure of 'Naked' Ga(I) and In(I) Salts and the Surprising Stability of Simple Ga(I) and In(I) Salts in the Coordinating Solvents Ether and Acetonitrile
Chemistry. 2024 Apr 10:e202400897. doi: 10.1002/chem.202400897. Online ahead of print.ABSTRACTIn this work, we present the solid-state structures of solvent-free Ga[pf] and In[pf] salts ([pf]- = [Al(ORF)4]-; RF = C(CF3)3), which are very rare examples of salts with truly 'naked' metal cations. Both salts may serve as starting materials for subvalent gallium and indium chemistry with very weakly coordinating ligands providing the freedom of choice for solvents and ligands for the future. On the other hand, we report and rationalize the formation and isolation of [M(OEt2)2][pf] and [M(MeCN)2][pf] (M = Ga, In), underlining th...
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Antoine Barth élemy Harald Scherer Hanna Weller Ingo Krossing Source Type: research
Linear, Planar, Orbicular, and Macrocyclic Multinuclear Zinc (Meth)acrylate Complexes
Chemistry. 2024 Apr 10:e202400586. doi: 10.1002/chem.202400586. Online ahead of print.ABSTRACTZinc carboxylate complexes are widely utilized as artificial models of metalloenzymes and as secondary building units of PCPs/MOFs. However, the relationship between the structure of the monodentate carboxylato ligand and the molecular arrangement of multinuclear zinc carboxylate complexes is not fully understood because of the coordination flexibility of the Zn ion and carboxylato ligands. Herein, we report the structural analysis of a series of complexes derived from zinc (meth)acrylate which has a linear infinite chain structur...
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Takanori Iwasaki Gaito Suehisa Hiroshi Tadaoka Kazuyoshi Shiga Kyoko Nozaki Source Type: research
Hydroxylamine-Mediated C(sp2)-H Trifluoromethylation of Terminal Alkenes
Chemistry. 2024 Apr 10:e202400995. doi: 10.1002/chem.202400995. Online ahead of print.ABSTRACTIntroduction of the trifluoromethyl (CF3) group into organic compounds has garnered substantial interest because of its significant role in pharmaceuticals and agrochemicals. Here, we report a hydroxylamine-mediated radical process for C(sp2)-H trifluoromethylation of terminal alkenes. The reaction shows good reactivity, impressive E/Z selectivity (up to > 20:1), and broad functional group compatibility. Expansion of this approach to perfluoroalkylation and late-stage trifluoromethylation of bioactive molecules demonstrates its...
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Xiao Zhao Bing Zhong Likun Dong Yu-Shan Zhang Hai-Tian Luo Jin-Dong Yang Jin-Pei Cheng Source Type: research
Photoreduction of Trifluoromethyl Group: Lithium Ion Assisted Fluoride-Coupled Electron Transfer from EDA Complex
Chemistry. 2024 Apr 10:e202400658. doi: 10.1002/chem.202400658. Online ahead of print.ABSTRACTPhotoinduced single-electron reduction is an efficient method for the mono-selective activation of the C-F bond on a trifluoromethyl group to construct a difluoroalkyl group. We have developed an electron-donor-acceptor (EDA) complex mediated single-electron transfer (EDA-SET) of α,α,α-trifluoromethyl arenes in the presence of lithium salt to give α,α-difluoroalkylarenes. The C-F bond reduction was realized by lithium iodide and triethylamine, two common feedstock reagents. Mechanistic studies revealed the generation of a α,...
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Tatsuhiro Uchikura Fua Akutsu Haruna Tani Takahiko Akiyama Source Type: research
Combined Covalent and Supramolecular Polymerization To Reinforce Perylenebisimide Photosynthetic "Quantasomes"
Chemistry. 2024 Apr 10:e202401061. doi: 10.1002/chem.202401061. Online ahead of print.ABSTRACTInvited for the cover of this issue are the groups of Marcella Bonchio at the University of Padova and Jérôme Canivet at the CNRS-University of Lyon. The image depicts the hierarchical self-organization of bio-inspired quantasomes, crosslinked within a polystyrene network to enchain their lateral and orthogonal proximity for long-lasting oxygen evolution using green photons. Read the full text of the article at 10.1002/chem.202303784.PMID:38595065 | DOI:10.1002/chem.202401061 (Source: Chemistry)
Source: Chemistry - April 10, 2024 Category: Chemistry Authors: Alisa Ranscht Francesco Rigodanza Thomas Gobbato Ilaria Crea Elsje Alessandra Quadrelli Jerome Canivet Marcella Bonchio Source Type: research
2-Aryl-3H-1,3-benzazaphosphole Oxides: Synthesis, Optical Properties, and Excited State Intramolecular Proton Transfer
We report on a series of 2-aryl-3H-1,3-benzazaphosphole oxides that were efficiently prepared via sequential C-P cross-coupling, dehydrative [3 + 2] cycloaddition, and ring-oxidation reactions. The inclusion of one nitrogen atom into the benzophosphole framework caused red shifting of the absorption and emission maxima, reflecting the greater stabilization of the LUMO level. 2-(2-Hydroxyphenyl)benzazaphosphole oxide underwent excited state intramolecular proton transfer and emitted a weak fluorescence from the excited state of the N-H tautomer.PMID:38590165 | DOI:10.1002/chem.202400807 (Source: Chemistry)
Source: Chemistry - April 9, 2024 Category: Chemistry Authors: Hiroaki Nakagomi Nina Murayama Rika Takegami Kaori Fujii Rio Kitakado Yoshifumi Kimura Mao Minoura Haruyuki Nakano Yoshihiro Matano Source Type: research
