Chemical Composition of Artemisia Scoparia and Their Bioactivities
Chem Biodivers. 2024 Mar 18:e202400414. doi: 10.1002/cbdv.202400414. Online ahead of print.ABSTRACTThree undescribed sesquiterpenes (1-3), two enantiomeric pairs of monoterpenes (4a/4b-5a/5b), one alkyne (6), two known alkynes (7-8) and eight known coumarins (9-16) were isolated from the aerial parts extracts of Artemisia scoparia. The structures of these compounds were fully elucidated by their 1D and 2D NMR, HRESIMS spectral data analyses, and comparison with literature. The absolute configurations of compounds were determined by single-crystal X-ray crystallography (1), a comparison of experimental and calculated electr...
Source: Chemistry and Biodiversity - March 19, 2024 Category: Biochemistry Authors: Guziliayi Kuerban Ablajan Turak Nurmirza Boymirzayevich Begmatov Jiangyu Zhao Haji Akber Aisa Source Type: research
A Comprehensive Examination of Heterocyclic Scaffold Chemistry for Antitubercular Activity
Chem Biodivers. 2024 Mar 18:e202400067. doi: 10.1002/cbdv.202400067. Online ahead of print.ABSTRACTTuberculosis is a communicable disease which affects humans particularly the lungs and is transmitted mainly through air. Despite two decades of intensive research aimed at understanding and combating tuberculosis, persistent biological uncertainties continue to hinder progress. Nowadays, heterocyclic compounds have proven themselves in effective treatment of tuberculosis because of their wide range of biological and pharmacological activities. Antituberculosis or antimycobacterial agents encompass a broad array of compounds ...
Source: Chemistry and Biodiversity - March 19, 2024 Category: Biochemistry Authors: Anjaneyulu Bendi Priyanka Yadav Komal Saini Anirudh Singh Bhathiwal Neera Raghav Source Type: research
Undescribed Lignanamide and Flavone C-glucoside Isolated from the Aerial Parts of Piper samentosum with NO Production Inhibitory Activity in LPS Activated RAW 264.7 Cells
In this study, two undescribed compounds (1 and 2), together with eight known compounds (3-10) were isolated from the aerial parts of Piper samentosum by various chromatography methods. Their chemical structures were determined to be 7'''-oxolyciumamide N (1), vitexin 2''-O-β-D-(6'''-feruloyl)-glucopyranoside (2), 1,2-dihydro-6,8-dimethoxy-7-hydroxy-1-(3,4-dihydroxyphenyl)-N1,N2-bis-[2-(-hydroxyphenyl)ethyl]-2,3-napthalene dicarboamide (3), vitexin 6''-O-β-D-glucopyranoside (4), vitexin 2''-O-α-L-rhamnopyranoside (5), methyl 2-hydroxybenzoate-2-O-β-D-apiofuranosyl-(1→2)-O-β-D-glucopyranoside (6), ficuside G (7), met...
Source: Chemistry and Biodiversity - March 19, 2024 Category: Biochemistry Authors: Le Thi Huyen Luu Nhu Thao Nhu Thi Hang Nga Quach Thi Khanh Ly Nguyen Thi Son Bui Huu Huu Tai Sy Thinh Ngo Phan Van Kiem Source Type: research
The First Comprehensive Chemical Profiling of Vachellia gummifera (Willd.) Kyal. & amp; Boatwr., a Plant with Medicinal Value
This report provides valuable insights into the chemotaxonomic significance of the Vachellia genus.PMID:38501581 | DOI:10.1002/cbdv.202400396 (Source: Chemistry and Biodiversity)
Source: Chemistry and Biodiversity - March 19, 2024 Category: Biochemistry Authors: Musa Kisiriko Clarice Noleto-Dias Gabin Bitchagno Imane Naboulsi Maria Anastasiadi Leon Terry Mansour Sobeh Michael Beale Jane Ward Source Type: research
Gc-ms and chemometric analysis of the essential oils obtained from mexican commercial chamomilla recutita teas
Chem Biodivers. 2024 Mar 19:e202400333. doi: 10.1002/cbdv.202400333. Online ahead of print.ABSTRACTThe essential oils prepared by hydrodistillation of twenty-one brands of German chamomile (S1-S21) commercialized in Mexico were analyzed by GS-MS. Altogether, twenty-four different compounds were identified in the analyzed samples, varying from 77 to 100 % of the total composition. Multivariate analyses were applied to explore similarity/dissimilarity and correlation between all samples; the results revealed a strong correlation among samples S4, S5, and S7-S21 due to the presence of (Z)-en-yn-dicycloether (Z- Tonghaosu), a-...
Source: Chemistry and Biodiversity - March 19, 2024 Category: Biochemistry Authors: Rachel Mata Araceli P érez-Vásquez Araceli Pe ña-Álvarez Source Type: research
New penta-coordinated cadmium(II) complexes: Synthesis, Characterization, Thermal, Antimicrobial, Antioxidant and Cytotoxicity Properties
Chem Biodivers. 2024 Mar 19:e202301667. doi: 10.1002/cbdv.202301667. Online ahead of print.ABSTRACTIn this paper, a new tridentate Schiff base ligand (L) with nitrogen donor atoms and its cadmium(II) complexes with the general formula of CdLX2 (X= Cl-,Br-,I-,SCN-,N3-,NO3-) have been synthesized and characterized by physical and spectral methods. Also nano-structured cadmium chloride and bromide complexes were synthesized by sonochemical method and then used to prepare nanostructured cadmium oxide confirmed by XRD and SEM techniques. Thermal behavior of the compounds was studied in the temperature range of 25 to 900 °C und...
Source: Chemistry and Biodiversity - March 19, 2024 Category: Biochemistry Authors: Morteza Montazerozohori M Nejadmirfathi R Naghiha E Panahi Kokhdan Source Type: research
Determination of Physicochemical Characteristics, Phytochemical Profile and Antioxidant Activity of Various Clover Honeys
Chem Biodivers. 2024 Mar 17:e202301880. doi: 10.1002/cbdv.202301880. Online ahead of print.NO ABSTRACTPMID:38494456 | DOI:10.1002/cbdv.202301880 (Source: Chemistry and Biodiversity)
Source: Chemistry and Biodiversity - March 18, 2024 Category: Biochemistry Authors: Sharmin Sultana Kevin Foster Tiffane Bates Md Lokman Hossain Lee Yong Lim Katherine Hammer Cornelia Locher Source Type: research
In vitro Evaluation of Skin Related Enzyme Inhibitory Effect and Emulgel Formulation Development Studies of Onobrychis argyrea subsp. argyrea with Phytochemical Analysis
In this study, it was aimed to investigate the skin-related biological activities and phytochemical characterization of OA. Moreover, an emulgel formulation was developed from the main methanolic extract of the plant (OAM). Initially, to identifiy of the active fractions, aerial parts of the plant material was extracted with methanol and fractionated by n-hexane, chloroform, ethyl acetate and n-butanol, respectively. Antioxidant activity was determined by CUPRAC, TOAC, FRAP and DPPH assays. Thereafter, the inhibition potential of OAM, novel formulation and all fractions was measured against elastase, collagenase, tyrosinas...
Source: Chemistry and Biodiversity - March 18, 2024 Category: Biochemistry Authors: Tu ğba Buse Şentürk Timur Hakan Barak Emre Şefik Çağlar Ebru Özdemir Nath Zafer Ömer Özdemir Source Type: research
Novel aminocoumarin derivatives against phytopathogenic fungi: design, synthesis and structure-activity relationships
Chem Biodivers. 2024 Mar 18:e202400311. doi: 10.1002/cbdv.202400311. Online ahead of print.ABSTRACTPhytopathogenic fungi is the most devastating reason for the decrease of the agricultural production and food safety. To develop new fungicidal agents for resistance concerning, a novel series of aminocoumarin derivatives were synthesized and their fungicidal activity were investigated both in vitro and in vivo. Transmission electron microscope (TEM), scanning electron microscope (SEM), RNA-Seq, 3D-QSAR and molecular docking were applied to reveal the underlying anti-fungal mechanisms. Most of the compounds exhibited signific...
Source: Chemistry and Biodiversity - March 18, 2024 Category: Biochemistry Authors: Pengzhi Sun Jiangping Pu Dongyu Lei Jiashan Li Xingyu Ren Lu Jin le Pan Source Type: research
Potential anti-gouty arthritis of Citronella essential oil and Nutmeg essential oil through reducing oxidative stress and inhibiting PI3K/Akt/mTOR activation-induced NLRP3 activity
This study aimed to investigate whether Citronella essential oil and Nutmeg essential oil (NEO) can ameliorate monosodium urate (MSU)-induced gouty arthritis in rats and the potential mechanisms. The results showed that CEO and NEO reduced swelling and redness at joint sites, inhibited neutrophil infiltration, and limited proinflammatory mediator secretion in mice with MSU-induced gouty arthritis. Based on the results of network pharmacology, molecular docking, and western blotting, CEO and NEO may exert anti-gouty arthritis effects by reducing the expression of reactive oxygen species and oxidative stress and downregulati...
Source: Chemistry and Biodiversity - March 18, 2024 Category: Biochemistry Authors: JinJin Yang Hongpeng Yu Kegang Wu Dong He Huadan Zhang ZhengXiang Cui Xianghua Chai Xuejuan Duan Source Type: research
Two New Benzoquinone Derivatives from Vietnamese Knema globularia Stems
Chem Biodivers. 2024 Mar 18:e202400380. doi: 10.1002/cbdv.202400380. Online ahead of print.ABSTRACTThe chemical investigation of the stems of Knema globularia led to the isolation of two new benzoquinones derivatives, embenones A and B (1 and 2), along with three known compounds (3-5). The structures of the isolated compounds were determined using spectroscopic techniques, including HRESIMS, 1D and 2D NMR, in conjunction with comparison to existing literature data. Compounds 1 and 2 represent new carbon skeletons in nature. Furthermore, all isolated compounds were evaluated for their α-glucosidase inhibitory activity, wit...
Source: Chemistry and Biodiversity - March 18, 2024 Category: Biochemistry Authors: Huy Truong Nguyen Thuc-Huy Duong Minh-Khai Dang Mai-Dang-Truong Pham Nguyen-Kim-Tuyen Pham Dinh Tri Mai Van Son Dang Ngoc-Hong Nguyen Jirapast Sichaem Source Type: research
Revolutionizing Infection Control: Harnessing MXene-Based Nanostructures for Versatile Antimicrobial Strategies and Healthcare Advancements
Chem Biodivers. 2024 Mar 18:e202400366. doi: 10.1002/cbdv.202400366. Online ahead of print.ABSTRACTThe escalating global health challenge posed by infections prompts the exploration of innovative solutions utilizing MXene-based nanostructures. Societally, the need for effective antimicrobial strategies is crucial for public health, while scientifically, MXenes present promising properties for therapeutic applications, necessitating scalable production and comprehensive characterization techniques. Here we review the versatile physicochemical properties of MXene materials for combatting microbial threats and their various s...
Source: Chemistry and Biodiversity - March 18, 2024 Category: Biochemistry Authors: Israa Habeeb Naser Youssef Ali Naeem Eyhab Ali Amina Yarab Hamed Nafaa Farhan Muften Fadhil Turky Maan Israa Hussein Mohammed Noor Alhuda Mohammad Ali Khalil Irfan Ahmad Mohammed Abed Jawad Ahmed Elwadi Source Type: research
Determination of Physicochemical Characteristics, Phytochemical Profile and Antioxidant Activity of Various Clover Honeys
Chem Biodivers. 2024 Mar 17:e202301880. doi: 10.1002/cbdv.202301880. Online ahead of print.NO ABSTRACTPMID:38494456 | DOI:10.1002/cbdv.202301880 (Source: Chemistry and Biodiversity)
Source: Chemistry and Biodiversity - March 18, 2024 Category: Biochemistry Authors: Sharmin Sultana Kevin Foster Tiffane Bates Md Lokman Hossain Lee Yong Lim Katherine Hammer Cornelia Locher Source Type: research
In vitro Evaluation of Skin Related Enzyme Inhibitory Effect and Emulgel Formulation Development Studies of Onobrychis argyrea subsp. argyrea with Phytochemical Analysis
In this study, it was aimed to investigate the skin-related biological activities and phytochemical characterization of OA. Moreover, an emulgel formulation was developed from the main methanolic extract of the plant (OAM). Initially, to identifiy of the active fractions, aerial parts of the plant material was extracted with methanol and fractionated by n-hexane, chloroform, ethyl acetate and n-butanol, respectively. Antioxidant activity was determined by CUPRAC, TOAC, FRAP and DPPH assays. Thereafter, the inhibition potential of OAM, novel formulation and all fractions was measured against elastase, collagenase, tyrosinas...
Source: Chemistry and Biodiversity - March 18, 2024 Category: Biochemistry Authors: Tu ğba Buse Şentürk Timur Hakan Barak Emre Şefik Çağlar Ebru Özdemir Nath Zafer Ömer Özdemir Source Type: research
Novel aminocoumarin derivatives against phytopathogenic fungi: design, synthesis and structure-activity relationships
Chem Biodivers. 2024 Mar 18:e202400311. doi: 10.1002/cbdv.202400311. Online ahead of print.ABSTRACTPhytopathogenic fungi is the most devastating reason for the decrease of the agricultural production and food safety. To develop new fungicidal agents for resistance concerning, a novel series of aminocoumarin derivatives were synthesized and their fungicidal activity were investigated both in vitro and in vivo. Transmission electron microscope (TEM), scanning electron microscope (SEM), RNA-Seq, 3D-QSAR and molecular docking were applied to reveal the underlying anti-fungal mechanisms. Most of the compounds exhibited signific...
Source: Chemistry and Biodiversity - March 18, 2024 Category: Biochemistry Authors: Pengzhi Sun Jiangping Pu Dongyu Lei Jiashan Li Xingyu Ren Lu Jin le Pan Source Type: research
