The role of abnormal ubiquitination in hepatocellular carcinoma pathology
In conclusion, targeting the dysregulation of ubiquitination in HCC holds promise as a prospective and complementary therapeutic approach to existing treatments.PMID:38036196 | DOI:10.1016/j.cellsig.2023.110994 (Source: Cellular Signalling)
Source: Cellular Signalling - November 30, 2023 Category: Cytology Authors: Ming Zhang Tingju Wei Danfeng Guo Source Type: research

Sevoflurane suppresses colorectal cancer malignancy by modulating β-catenin ubiquitination degradation via circSKA3
CONCLUSIONS: All the results showed that SEV could inhibit CRC progression via circSKA3 by increasing β-catenin ubiquitination degradation.PMID:38029946 | DOI:10.1016/j.cellsig.2023.110987 (Source: Cellular Signalling)
Source: Cellular Signalling - November 29, 2023 Category: Cytology Authors: Wen Song Liping Miao Kun Zhang Yafang Liu Jiatong Lin Junhua Li Zeqi Huang Dong Cao Yuchao Zhang Chuwen Hu Source Type: research

A prognostic model based on Scissor < sup > + < /sup > cancer associated fibroblasts identified from bulk and single cell RNA sequencing data in head and neck squamous cell carcinoma
In conclusion, we constructed an optimal model that was derived from single cell RNA-seq and bulk RNA-seq to predict the survival probability of HNSCC patients. Among this model, AKR1C3 higher expression in cancer associated fibroblasts (CAFs) of HNSCC has been confirmed by preliminary experiments.PMID:38029947 | DOI:10.1016/j.cellsig.2023.110984 (Source: Cellular Signalling)
Source: Cellular Signalling - November 29, 2023 Category: Cytology Authors: Guoli Tian Jiaqiang Zhang Yong Bao Qiuli Li Jinsong Hou Source Type: research

Sevoflurane suppresses colorectal cancer malignancy by modulating β-catenin ubiquitination degradation via circSKA3
CONCLUSIONS: All the results showed that SEV could inhibit CRC progression via circSKA3 by increasing β-catenin ubiquitination degradation.PMID:38029946 | DOI:10.1016/j.cellsig.2023.110987 (Source: Cellular Signalling)
Source: Cellular Signalling - November 29, 2023 Category: Cytology Authors: Wen Song Liping Miao Kun Zhang Yafang Liu Jiatong Lin Junhua Li Zeqi Huang Dong Cao Yuchao Zhang Chuwen Hu Source Type: research

A prognostic model based on Scissor < sup > + < /sup > cancer associated fibroblasts identified from bulk and single cell RNA sequencing data in head and neck squamous cell carcinoma
In conclusion, we constructed an optimal model that was derived from single cell RNA-seq and bulk RNA-seq to predict the survival probability of HNSCC patients. Among this model, AKR1C3 higher expression in cancer associated fibroblasts (CAFs) of HNSCC has been confirmed by preliminary experiments.PMID:38029947 | DOI:10.1016/j.cellsig.2023.110984 (Source: Cellular Signalling)
Source: Cellular Signalling - November 29, 2023 Category: Cytology Authors: Guoli Tian Jiaqiang Zhang Yong Bao Qiuli Li Jinsong Hou Source Type: research