Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov;43(8):4071-4101. doi: 10.1007/s10571-023-01432-7. Epub 2023 Nov 13.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associ...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov 13. doi: 10.1007/s10571-023-01432-7. Online ahead of print.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associated wit...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov 13. doi: 10.1007/s10571-023-01432-7. Online ahead of print.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associated wit...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov 13. doi: 10.1007/s10571-023-01432-7. Online ahead of print.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associated wit...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research

Methyl-CpG-Binding Protein 2 Emerges as a Central Player in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Cell Mol Neurobiol. 2023 Nov 13. doi: 10.1007/s10571-023-01432-7. Online ahead of print.ABSTRACTMECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are inflammatory, autoimmune, and demyelinating disorders of the central nervous system (CNS). However, the mechanisms and pathways regulated by MeCP2 in immune activation in favor of MS and NMOSD are not fully understood. We summarize findings that use the binding properties of MeCP2 to identify its targets, particularly the genes recognized by MeCP2 and associated wit...
Source: Cellular and Molecular Neurobiology - November 13, 2023 Category: Cytology Authors: Arshad Mehmood Suleman Shah Ruo-Yi Guo Arsalan Haider Mengya Shi Hamid Ali Ijaz Ali Riaz Ullah Bin Li Source Type: research