Effects of syndecan-4 silencing on the extracellular matrix remodeling in anoikis-resistant endothelial cells
In conclusion, these data demonstrate that SDC4 plays an important role in ECM remodeling. In addition, our findings represent an important step toward understanding the mechanism by which SDC4 can reverse the transformed phenotype of anoikis-resistant endothelial cells.PMID:38591778 | DOI:10.1002/cbin.12158 (Source: Cell Biology International)
Source: Cell Biology International - April 9, 2024 Category: Cytology Authors: Jessica Oyie Sousa Onyeisi Helena Bonciani Nader Carla Cristina Lopes Source Type: research
L-kynurenine and quinolinic acid inhibited markers of cell survival in B16 F10 melanoma cells in vitro
Cell Biol Int. 2024 Apr 3. doi: 10.1002/cbin.12163. Online ahead of print.ABSTRACTMelanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity and morphological changes in B16 F10 melanoma cells in vitro. This paper highlights the effects of L-kynurenine and quinolinic acid at previously determined half-maximal inhibitory concentrations on cell cycle progression, cell death and extracellular signal-regulated protein kinase inhibition. Melanoma, B16 F10 and murine...
Source: Cell Biology International - April 4, 2024 Category: Cytology Authors: Charlise Basson June Cheptoo Serem Priyesh Bipath Yvette Nkondo Hlophe Source Type: research
L-kynurenine and quinolinic acid inhibited markers of cell survival in B16 F10 melanoma cells in vitro
Cell Biol Int. 2024 Apr 3. doi: 10.1002/cbin.12163. Online ahead of print.ABSTRACTMelanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity and morphological changes in B16 F10 melanoma cells in vitro. This paper highlights the effects of L-kynurenine and quinolinic acid at previously determined half-maximal inhibitory concentrations on cell cycle progression, cell death and extracellular signal-regulated protein kinase inhibition. Melanoma, B16 F10 and murine...
Source: Cell Biology International - April 4, 2024 Category: Cytology Authors: Charlise Basson June Cheptoo Serem Priyesh Bipath Yvette Nkondo Hlophe Source Type: research
L-kynurenine and quinolinic acid inhibited markers of cell survival in B16 F10 melanoma cells in vitro
Cell Biol Int. 2024 Apr 3. doi: 10.1002/cbin.12163. Online ahead of print.ABSTRACTMelanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity and morphological changes in B16 F10 melanoma cells in vitro. This paper highlights the effects of L-kynurenine and quinolinic acid at previously determined half-maximal inhibitory concentrations on cell cycle progression, cell death and extracellular signal-regulated protein kinase inhibition. Melanoma, B16 F10 and murine...
Source: Cell Biology International - April 4, 2024 Category: Cytology Authors: Charlise Basson June Cheptoo Serem Priyesh Bipath Yvette Nkondo Hlophe Source Type: research
L-kynurenine and quinolinic acid inhibited markers of cell survival in B16 F10 melanoma cells in vitro
Cell Biol Int. 2024 Apr 3. doi: 10.1002/cbin.12163. Online ahead of print.ABSTRACTMelanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity and morphological changes in B16 F10 melanoma cells in vitro. This paper highlights the effects of L-kynurenine and quinolinic acid at previously determined half-maximal inhibitory concentrations on cell cycle progression, cell death and extracellular signal-regulated protein kinase inhibition. Melanoma, B16 F10 and murine...
Source: Cell Biology International - April 4, 2024 Category: Cytology Authors: Charlise Basson June Cheptoo Serem Priyesh Bipath Yvette Nkondo Hlophe Source Type: research
L-kynurenine and quinolinic acid inhibited markers of cell survival in B16 F10 melanoma cells in vitro
Cell Biol Int. 2024 Apr 3. doi: 10.1002/cbin.12163. Online ahead of print.ABSTRACTMelanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity and morphological changes in B16 F10 melanoma cells in vitro. This paper highlights the effects of L-kynurenine and quinolinic acid at previously determined half-maximal inhibitory concentrations on cell cycle progression, cell death and extracellular signal-regulated protein kinase inhibition. Melanoma, B16 F10 and murine...
Source: Cell Biology International - April 4, 2024 Category: Cytology Authors: Charlise Basson June Cheptoo Serem Priyesh Bipath Yvette Nkondo Hlophe Source Type: research
RAD23B mediated proteasomal degradation occurs through p38 MAPK/ATF-2/RAD23B axis under nutrient-deprived conditions in breast cancer
Cell Biol Int. 2024 Apr 1. doi: 10.1002/cbin.12160. Online ahead of print.ABSTRACTMetabolic reprogramming in cancer occurs due to interaction of cells with the surrounding tumor microenvironment. In the microenvironment of solid tumors, nutrient deprivation is induced by high consumption of nutrients and insufficient vasculature. Tumor cells alter their metabolic strategies to adapt to the microenvironment. To understand the role of these metabolic changes, in the current study, we have mimicked nutrient deprivation condition in vitro to evaluate the associated signaling pathways in breast cancer cells. In our study, we ha...
Source: Cell Biology International - April 2, 2024 Category: Cytology Authors: Sukumaran Sriaishwarya Baddireddi Subhadra Lakshmi Source Type: research
Daurisoline inhibits proliferation, induces apoptosis, and enhances TRAIL sensitivity of breast cancer cells by upregulating DR5
This study provides valuable insights into the mechanisms of DS inhibiting cell proliferation, triggering apoptosis, and enhancing TRAIL sensitivity of breast cancer cells.PMID:38563483 | DOI:10.1002/cbin.12162 (Source: Cell Biology International)
Source: Cell Biology International - April 2, 2024 Category: Cytology Authors: Xin Liu Lin-Lin Wang Cun-Yu Duan Yan-Ru Rong Ya-Qi Liang Qing-Xiang Zhu Gang-Ping Hao Feng-Ze Wang Source Type: research
RAD23B mediated proteasomal degradation occurs through p38 MAPK/ATF-2/RAD23B axis under nutrient-deprived conditions in breast cancer
Cell Biol Int. 2024 Apr 1. doi: 10.1002/cbin.12160. Online ahead of print.ABSTRACTMetabolic reprogramming in cancer occurs due to interaction of cells with the surrounding tumor microenvironment. In the microenvironment of solid tumors, nutrient deprivation is induced by high consumption of nutrients and insufficient vasculature. Tumor cells alter their metabolic strategies to adapt to the microenvironment. To understand the role of these metabolic changes, in the current study, we have mimicked nutrient deprivation condition in vitro to evaluate the associated signaling pathways in breast cancer cells. In our study, we ha...
Source: Cell Biology International - April 2, 2024 Category: Cytology Authors: Sukumaran Sriaishwarya Baddireddi Subhadra Lakshmi Source Type: research
Daurisoline inhibits proliferation, induces apoptosis, and enhances TRAIL sensitivity of breast cancer cells by upregulating DR5
This study provides valuable insights into the mechanisms of DS inhibiting cell proliferation, triggering apoptosis, and enhancing TRAIL sensitivity of breast cancer cells.PMID:38563483 | DOI:10.1002/cbin.12162 (Source: Cell Biology International)
Source: Cell Biology International - April 2, 2024 Category: Cytology Authors: Xin Liu Lin-Lin Wang Cun-Yu Duan Yan-Ru Rong Ya-Qi Liang Qing-Xiang Zhu Gang-Ping Hao Feng-Ze Wang Source Type: research
An optimized protocol for routine development of cell culture from adult oyster, Crassostrea madrasensis
Cell Biol Int. 2024 Mar 27. doi: 10.1002/cbin.12159. Online ahead of print.ABSTRACTMarine molluscan cell lines, required for virus screening and cultivation, form essential tools for developing health management strategies for these animals in the blue economy. Moreover, they are also crucial to develop cultivated seafood. As there is no valid marine molluscan cell line, primary cell cultures are relied upon for all investigations. A sound protocol for generating primary cell cultures from molluscs is entailed, but existing protocols often involve heavy antibiotic usage and depuration that invariably affect gene expression...
Source: Cell Biology International - March 27, 2024 Category: Cytology Authors: Soumya Balakrishnan Ambadi Kannan Maliyekkal Sajeevan Sreevidya Chandrasekharan Parvathi I S Bright Singh Jayesh Puthumana Source Type: research
An optimized protocol for routine development of cell culture from adult oyster, Crassostrea madrasensis
Cell Biol Int. 2024 Mar 27. doi: 10.1002/cbin.12159. Online ahead of print.ABSTRACTMarine molluscan cell lines, required for virus screening and cultivation, form essential tools for developing health management strategies for these animals in the blue economy. Moreover, they are also crucial to develop cultivated seafood. As there is no valid marine molluscan cell line, primary cell cultures are relied upon for all investigations. A sound protocol for generating primary cell cultures from molluscs is entailed, but existing protocols often involve heavy antibiotic usage and depuration that invariably affect gene expression...
Source: Cell Biology International - March 27, 2024 Category: Cytology Authors: Soumya Balakrishnan Ambadi Kannan Maliyekkal Sajeevan Sreevidya Chandrasekharan Parvathi I S Bright Singh Jayesh Puthumana Source Type: research
An optimized protocol for routine development of cell culture from adult oyster, Crassostrea madrasensis
Cell Biol Int. 2024 Mar 27. doi: 10.1002/cbin.12159. Online ahead of print.ABSTRACTMarine molluscan cell lines, required for virus screening and cultivation, form essential tools for developing health management strategies for these animals in the blue economy. Moreover, they are also crucial to develop cultivated seafood. As there is no valid marine molluscan cell line, primary cell cultures are relied upon for all investigations. A sound protocol for generating primary cell cultures from molluscs is entailed, but existing protocols often involve heavy antibiotic usage and depuration that invariably affect gene expression...
Source: Cell Biology International - March 27, 2024 Category: Cytology Authors: Soumya Balakrishnan Ambadi Kannan Maliyekkal Sajeevan Sreevidya Chandrasekharan Parvathi I S Bright Singh Jayesh Puthumana Source Type: research
An optimized protocol for routine development of cell culture from adult oyster, Crassostrea madrasensis
Cell Biol Int. 2024 Mar 27. doi: 10.1002/cbin.12159. Online ahead of print.ABSTRACTMarine molluscan cell lines, required for virus screening and cultivation, form essential tools for developing health management strategies for these animals in the blue economy. Moreover, they are also crucial to develop cultivated seafood. As there is no valid marine molluscan cell line, primary cell cultures are relied upon for all investigations. A sound protocol for generating primary cell cultures from molluscs is entailed, but existing protocols often involve heavy antibiotic usage and depuration that invariably affect gene expression...
Source: Cell Biology International - March 27, 2024 Category: Cytology Authors: Soumya Balakrishnan Ambadi Kannan Maliyekkal Sajeevan Sreevidya Chandrasekharan Parvathi I S Bright Singh Jayesh Puthumana Source Type: research
An optimized protocol for routine development of cell culture from adult oyster, Crassostrea madrasensis
Cell Biol Int. 2024 Mar 27. doi: 10.1002/cbin.12159. Online ahead of print.ABSTRACTMarine molluscan cell lines, required for virus screening and cultivation, form essential tools for developing health management strategies for these animals in the blue economy. Moreover, they are also crucial to develop cultivated seafood. As there is no valid marine molluscan cell line, primary cell cultures are relied upon for all investigations. A sound protocol for generating primary cell cultures from molluscs is entailed, but existing protocols often involve heavy antibiotic usage and depuration that invariably affect gene expression...
Source: Cell Biology International - March 27, 2024 Category: Cytology Authors: Soumya Balakrishnan Ambadi Kannan Maliyekkal Sajeevan Sreevidya Chandrasekharan Parvathi I S Bright Singh Jayesh Puthumana Source Type: research
