Pediatric Autoimmune Neuropsychiatric Disorder Linked to Streptococcal Infections
Case Rep Psychiatry. 2023 Dec 11;2023:6667272. doi: 10.1155/2023/6667272. eCollection 2023.ABSTRACTPediatric acute-onset neuropsychiatric syndrome (PANS) is a clinical condition with abrupt onset of obsessive-compulsive symptoms and/or severe eating restrictions and at least two concomitant cognitive, behavioral, or neurological symptoms. Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS) is a subtype of PANS with a controversial diagnosis. A case of a 12-year-old girl with severe eating restriction, obsessive-compulsive symptoms, anxiety, and neurological symptoms who initiall...
Source: Case Reports in Psychiatry - December 20, 2023 Category: Psychiatry Authors: Abdullah Nasser Alqifari Benjamin Maxwell Source Type: research

Clozapine Serum Concentrations Are Disrupted by SARS-CoV-2 Vaccinations
Case Rep Psychiatry. 2023 Nov 27;2023:9914879. doi: 10.1155/2023/9914879. eCollection 2023.ABSTRACTThis paper reports the case of a 27-year-old man with paranoid schizophrenia who was finally stabilized on clozapine medication. After vaccination against severe acute respiratory syndrome coronavirus 2, serum levels of clozapine increased. It is well established that immune responses can trigger cytokine cascades affecting drug metabolism, which, in the case of clozapine treatment, can lead to severe intoxication.PMID:38058314 | PMC:PMC10696469 | DOI:10.1155/2023/9914879 (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - December 7, 2023 Category: Psychiatry Authors: Xenia A K Kersting Nicoletta Momtahen Klaus Lieb Source Type: research