The Function of Circular RNAs in Myocardial Ischemia –Reperfusion Injury: Underlying Mechanisms and Therapeutic Advancement
AbstractMyocardial ischemia reperfusion injury (MIRI) represents a prevalent and severe cardiovascular condition that arises primarily after myocardial infarction recanalization, cardiopulmonary bypass surgery, and both stable and unstable angina pectoris. MIRI can induce malignant arrhythmias and heart failure, thereby increasing the morbidity and mortality rates associated with cardiovascular diseases. Hence, it is important to assess the potential pathological mechanisms of MIRI and develop effective treatments. The role of circular RNAs (circRNAs) in MIRI has increasingly become a topic of interest in recent years. Mor...
Source: Cardiovascular Drugs and Therapy - January 30, 2024 Category: Cardiology Source Type: research
Hyperkalaemia in Cardiological Patients: New Solutions for an Old Problem
AbstractHyperkalaemia is one of the most common electrolyte disorders in patients with cardiovascular disease (CVD). The true burden of hyperkalaemia in the real-world setting can be difficult to assess, but in population-based cohort studies up to 4 in 10 patients developed hyperkalaemia. In addition to drugs interfering with potassium metabolism and food intake, several conditions can cause or worsen hyperkalaemia, such as advanced age, diabetes, and chronic kidney disease. Mortality, cardiovascular morbidity, and hospitalisation are higher in patients with hyperkalaemia. Hyperkalaemia represents a major contraindication...
Source: Cardiovascular Drugs and Therapy - January 30, 2024 Category: Cardiology Source Type: research
Changes in Heart Rate Variability Parameters Following Radiofrequency Ablation in Patients with Atrial Fibrillation: A Systematic Review and Meta-Analysis
ConclusionThis meta-analysis suggests the potential of decreased HRV as an indicator of autonomic denervation, necessitating further exploration to optimize therapeutic strategies and enhance patient outcomes. (Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 30, 2024 Category: Cardiology Source Type: research
The Function of Circular RNAs in Myocardial Ischemia –Reperfusion Injury: Underlying Mechanisms and Therapeutic Advancement
AbstractMyocardial ischemia reperfusion injury (MIRI) represents a prevalent and severe cardiovascular condition that arises primarily after myocardial infarction recanalization, cardiopulmonary bypass surgery, and both stable and unstable angina pectoris. MIRI can induce malignant arrhythmias and heart failure, thereby increasing the morbidity and mortality rates associated with cardiovascular diseases. Hence, it is important to assess the potential pathological mechanisms of MIRI and develop effective treatments. The role of circular RNAs (circRNAs) in MIRI has increasingly become a topic of interest in recent years. Mor...
Source: Cardiovascular Drugs and Therapy - January 30, 2024 Category: Cardiology Source Type: research
Hyperkalaemia in Cardiological Patients: New Solutions for an Old Problem
AbstractHyperkalaemia is one of the most common electrolyte disorders in patients with cardiovascular disease (CVD). The true burden of hyperkalaemia in the real-world setting can be difficult to assess, but in population-based cohort studies up to 4 in 10 patients developed hyperkalaemia. In addition to drugs interfering with potassium metabolism and food intake, several conditions can cause or worsen hyperkalaemia, such as advanced age, diabetes, and chronic kidney disease. Mortality, cardiovascular morbidity, and hospitalisation are higher in patients with hyperkalaemia. Hyperkalaemia represents a major contraindication...
Source: Cardiovascular Drugs and Therapy - January 30, 2024 Category: Cardiology Source Type: research
Changes in Heart Rate Variability Parameters Following Radiofrequency Ablation in Patients with Atrial Fibrillation: A Systematic Review and Meta-Analysis
ConclusionThis meta-analysis suggests the potential of decreased HRV as an indicator of autonomic denervation, necessitating further exploration to optimize therapeutic strategies and enhance patient outcomes. (Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 30, 2024 Category: Cardiology Source Type: research
Open Issues in the Management of Otcagerian Patients with Atrial Fibrillation and Chronic Kidney Disease: Are we Ready for Left Atrial Appendage Occlusion (LAAO) as First-Line Therapy for Thromboembolic Risk Prevention?
(Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 26, 2024 Category: Cardiology Source Type: research
Comparison Between Drug-Coated Balloon and Stents in Large De Novo Coronary Artery Disease: A Systematic Review and Meta-Analysis of RCT Data
ConclusionDCB may be an effective therapeutic option in patients with large vessel de novo coronary artery disease. (Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 25, 2024 Category: Cardiology Source Type: research
The Toll-like Receptor-2/4 Antagonist, Sparstolonin B, and Inflammatory Diseases: A Literature Mining and Network Analysis
ConclusionThese results emphasized the importance of TLR2/TLR4-MyD88-NF- κB-IL-1β/IL-6/TNF-α pathways as therapeutic targets of SsnB in inflammatory diseases. (Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 25, 2024 Category: Cardiology Source Type: research
Instent CTO —What Is the Best Treatment Strategy?
(Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 25, 2024 Category: Cardiology Source Type: research
Comparison Between Drug-Coated Balloon and Stents in Large De Novo Coronary Artery Disease: A Systematic Review and Meta-Analysis of RCT Data
ConclusionDCB may be an effective therapeutic option in patients with large vessel de novo coronary artery disease. (Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 25, 2024 Category: Cardiology Source Type: research
The Toll-like Receptor-2/4 Antagonist, Sparstolonin B, and Inflammatory Diseases: A Literature Mining and Network Analysis
ConclusionThese results emphasized the importance of TLR2/TLR4-MyD88-NF- κB-IL-1β/IL-6/TNF-α pathways as therapeutic targets of SsnB in inflammatory diseases. (Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 25, 2024 Category: Cardiology Source Type: research
Instent CTO —What Is the Best Treatment Strategy?
(Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 25, 2024 Category: Cardiology Source Type: research
Numbers Needed to Treat for Preventing Adverse Cardiovascular Outcomes for Sodium-Glucose Cotransporter 2 Inhibitors vs. Dipeptidyl Peptidase 4 Inhibitors: The Hong Kong Diabetes Study
(Source: Cardiovascular Drugs and Therapy)
Source: Cardiovascular Drugs and Therapy - January 20, 2024 Category: Cardiology Source Type: research
