Cancer Epidemiology Biomarkers and Prevention 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Young Adult and Usual Adult Body Mass Index and Multiple Myeloma Risk: A Pooled Analysis in the International Multiple Myeloma Consortium (IMMC)
Conclusions: BMI-associated increases in multiple myeloma risk were highest for individuals who were overweight or obese throughout adulthood.
Impact: These findings provide the strongest evidence to date that earlier and later adult BMI may increase multiple myeloma risk and suggest that healthy BMI maintenance throughout life may confer an added benefit of multiple myeloma prevention. Cancer Epidemiol Biomarkers Prev; 26(6); 876–85. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Birmann, B. M., Andreotti, G., De Roos, A. J., Camp, N. J., Chiu, B. C. H., Spinelli, J. J., Becker, N., Benhaim-Luzon, V., Bhatti, P., Boffetta, P., Brennan, P., Brown, E. E., Cocco, P., Costas, L., Cozen, W., de Sanjose, S., Foretova, L., Giles, G. G., Tags: Research Articles Source Type: research
Insurance Status and Racial Disparities in Cancer-Specific Mortality in the United States: A Population-Based Analysis
Conclusions: The disparity between blacks and whites was largest, and the advantage of Hispanic race was absent within the non-Medicaid subgroup.
Impact: These findings suggest that whites derive greater benefit from private insurance than blacks and Hispanics. Further research is necessary to determine why this differential exists and how disparities can be improved. Cancer Epidemiol Biomarkers Prev; 26(6); 869–75. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Pan, H. Y., Walker, G. V., Grant, S. R., Allen, P. K., Jiang, J., Guadagnolo, B. A., Smith, B. D., Koshy, M., Rusthoven, C. G., Mahmood, U. Tags: Research Articles Source Type: research
Diabetes, Abnormal Glucose, Dyslipidemia, Hypertension, and Risk of Inflammatory and Other Breast Cancer
Conclusions: Associations with diabetes and dyslipidemia were similar for distant stage IBC and other advanced tumors.
Impact: If confirmed, such findings could suggest avenues for prevention. Cancer Epidemiol Biomarkers Prev; 26(6); 862–8. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Schairer, C., Gadalla, S. M., Pfeiffer, R. M., Moore, S. C., Engels, E. A. Tags: Research Articles Source Type: research
Type II Diabetes, Obesity, and Breast Cancer Risk: The Multiethnic Cohort
Conclusions: As reported previously, inclusion of BMI weakened the association of type II diabetes with breast cancer. Type II diabetes status, but not BMI, was primarily associated with higher breast cancer risk in Latinas.
Impact: The role of obesity and type II diabetes in breast cancer etiology may differ by ethnicity suggesting metabolic differences related to obesity. Cancer Epidemiol Biomarkers Prev; 26(6); 854–61. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Maskarinec, G., Jacobs, S., Park, S.-Y., Haiman, C. A., Setiawan, V. W., Wilkens, L. R., Le Marchand, L. Tags: Research Articles Source Type: research
Aspirin Use Reduces the Risk of Aggressive Prostate Cancer and Disease Recurrence in African-American Men
Conclusions: Regular aspirin use is associated with a decreased risk of advanced stage prostate cancer and increased disease-free survival in AA men.
Impact: Regular aspirin use before and after a prostate cancer diagnosis may prevent the development of aggressive disease in AA men who are at risk of a lethal malignancy. Cancer Epidemiol Biomarkers Prev; 26(6); 845–53. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Smith, C. J., Dorsey, T. H., Tang, W., Jordan, S. V., Loffredo, C. A., Ambs, S. Tags: Research Articles Source Type: research
Estimating TP53 Mutation Carrier Probability in Families with Li-Fraumeni Syndrome Using LFSPRO
Conclusions: LFSPRO shows good performance in predicting TP53 mutations in individuals and families in varied situations.
Impact: LFSPRO is more broadly applicable than the current clinical criteria and may improve clinical management for individuals and families with LFS. Cancer Epidemiol Biomarkers Prev; 26(6); 837–44. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Peng, G., Bojadzieva, J., Ballinger, M. L., Li, J., Blackford, A. L., Mai, P. L., Savage, S. A., Thomas, D. M., Strong, L. C., Wang, W. Tags: Research Articles Source Type: research
Nut Consumption and Lung Cancer Risk: Results from Two Large Observational Studies
Conclusions: Nut consumption was inversely associated with lung cancer in two large population-based studies, and associations were independent of cigarette smoking and other known risk factors.
Impact: To our knowledge, this is the first study that examined the association between nut consumption and lung cancer risk by histologic subtypes and smoking intensity. Cancer Epidemiol Biomarkers Prev; 26(6); 826–36. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Lee, J. T., Lai, G. Y., Liao, L. M., Subar, A. F., Bertazzi, P. A., Pesatori, A. C., Freedman, N. D., Landi, M. T., Lam, T. K. Tags: Research Articles Source Type: research
Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium
Conclusions: Functional and correlative studies are now needed to elucidate the potential links between germline genotype, epigenetic function, and cancer etiology.
Impact: This approach provides novel insight into possible pleiotropic effects of genes involved in epigenetic processes. Cancer Epidemiol Biomarkers Prev; 26(6); 816–25. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Toth, R., Scherer, D., Kelemen, L. E., Risch, A., Hazra, A., Balavarca, Y., Issa, J.-P. J., Moreno, V., Eeles, R. A., Ogino, S., Wu, X., Ye, Y., Hung, R. J., Goode, E. L., Ulrich, C. M., on behalf of the OCAC, CORECT, TRICL, ELLIPSE, DRIVE, and GAME-ON co Tags: Research Articles Source Type: research
Estimation of the Number of Women Living with Metastatic Breast Cancer in the United States
Conclusions: This study demonstrates an increasing number of women in the United States living with MBC, likely the result of improvements in treatment and aging of the U.S. population.
Impact: The increasing burden of MBC highlights the importance of documenting recurrence to foster more research into the specific needs of this understudied population. Cancer Epidemiol Biomarkers Prev; 26(6); 809–15. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Authors: Mariotto, A. B., Etzioni, R., Hurlbert, M., Penberthy, L., Mayer, M. Tags: Cancer Surveillance Research Source Type: research
Highlights of This Issue
(Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - May 31, 2017 Category: Cancer & Oncology Tags: Highlights Source Type: research
Abstract A30: Affordability of screening, race and marital status predict early detection of breast cancer: Analysis of cancer registry data
Conclusion: Affordability of cancer screening services plays an important role in early detection of breast cancer. Hence, the coverage of preventive services through the Affordable Care Act is likely to be a positive policy change leading to higher screening rates and thereby, higher rates of early detection of breast cancer. Further, there exist racial disparities in early diagnosis of breast cancer that may be due to differential access to screening services. Targeted policy efforts will be needed to address these disparities to improve outcomes of breast cancer for all race groups.Citation Format: Aastha Chandak, Preet...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Chandak, A., Nayar, P., Kan, G., Gupta, N. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Poster Presentations - Proffered Abstracts Source Type: research
Abstract B29: Terahertz spectral imaging and scanning for early detection of skin cancer
A terahertz diagnosis tool has been developed to identify early stage skin cancer at the cellular level. Here, three different techniques are used where each technique independently identifies a given disease condition compared to healthy skin specimen; thus, collectively forms a diagnostic procedure with minimal falls alarm. Namely, terahertz sub-surface spectral imaging, terahertz absorbance spectroscopy and skin thickness profiling have been used. Terahertz radiation is non-ionizing, therefore, save for in-vivo investigations. It is also more sensitive than other forms of probing energies. In the present work, biopsies ...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Rahman, A., Rahman, A. K., Rao, B. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Poster Presentations - Proffered Abstracts Source Type: research
Abstract A29: Mathematical models are not the be-all and end-all for breast cancer risk assessment
Conclusions: Our institutional high-risk database includes women who are at high risk based on well-established risk factors for developing breast cancer (FH, BRCA mutations, AH, LCIS). Current mathematical models including the Gail and Tyrer-Cuzick models did not capture the increased risk of breast cancer in 8% of our population. While the models are helpful, in clinical practice they are not necessarily the be-all and end-all. Using heuristic risk factors is more time efficient and comprehensive risk assessment allows the clinicians and patients to better understand risk. Identifying patients as high risk and enrolling ...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Schnabel, F., Chun, J., Schwartz, S., Guth, A., Axelrod, D., Shapiro, R., Hiotis, K., Smith, J. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Poster Presentations - Proffered Abstracts Source Type: research
Abstract B28: Clinicopathological features associated with late recurrence of gastric cancer
Conclusion: Late recurrence of gastric cancer is possibly not influenced by advanced stage of primary disease. More attempts to find high risk groups for late recurrence of gastric cancer are needed.Citation Format: Ji Soo Park, Chu Ree Won, Taeil Son, Hyoung-Il Kim, Woo Jin Hyung, Sung Hoon Noh, Tae Il Kim. Clinicopathological features associated with late recurrence of gastric cancer. [abstract]. In: Proceedings of the AACR Special Conference: Improving Cancer Risk Prediction for Prevention and Early Detection; Nov 16-19, 2016; Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2017;26(5 Suppl):Abstra...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Park, J. S., Won, C. R., Son, T., Kim, H.-I., Hyung, W. J., Noh, S. H., Kim, T. I. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Poster Presentations - Proffered Abstracts Source Type: research
Abstract A28: Risk model for clinical management of HPV-infected women
Conclusions: Based on our preliminary results, the fate of most HPV infections is determined within a few years of first detection, based mainly on characteristics of the virus. MRS summarizes the average risk discrimination of the prediction model compared to pre-test probability, permitting estimation of its expected benefit. We hypothesize and will test whether multivariate calculations of absolute risks and the use of mean risk stratification can lead to improved risk-based clinical management of HPV-infected women.Citation Format: Maria Demarco, Noorie Hyun, Hormuzd Katki, Brian Befano, Li Cheung, Tina R. Raine-Bennet...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Demarco, M., Hyun, N., Katki, H., Befano, B., Cheung, L., Raine-Bennett, T. R., Fetterman, B., Lorey, T., Poitras, N., Gage, J. C., Castle, P. E., Wentzensen, N., Schiffman, M. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Poster Presentations - Proffered Abstracts Source Type: research
