Targeted, Deep Sequencing Reveals Full Methylation Profiles of Multiple HPV Types and Potential Biomarkers for Cervical Cancer Progression
Conclusions: Global HPV methylation is significantly higher in ICC than CIN3, with L1 gene methylation levels performing best for distinguishing CIN3 from ICC. Methylation levels at CpGs in the E1 gene of HPV 16 (972, 978, 1870, and 1958) can distinguish between CIN3 and ICC. Impact: Higher methylation at specific E1 CpGs may associate with increased likelihood of progression to ICC in HPV 16–positive CIN3 lesions. Cancer Epidemiol Biomarkers Prev; 26(4); 642–50. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Liu, P., Iden, M., Fye, S., Huang, Y.-W., Hopp, E., Chu, C., Lu, Y., Rader, J. S. Tags: Research Articles Source Type: research

Cancer Incidence and Survival Trends by Subtype Using Data from the Surveillance Epidemiology and End Results Program, 1992-2013
Conclusions: Histologic or molecular subtype revealed different incidence and/or survival trends that are masked when cancer is considered as a single disease on the basis of anatomic site. Impact: Presenting incidence and survival trends by subtype, whenever possible, is critical to provide more detailed and meaningful data to patients, providers, and the public. Cancer Epidemiol Biomarkers Prev; 26(4); 632–41. ©2016 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Noone, A.-M., Cronin, K. A., Altekruse, S. F., Howlader, N., Lewis, D. R., Petkov, V. I., Penberthy, L. Tags: Research Articles Source Type: research

Cytotoxic T Cells and Granzyme B Associated with Improved Colorectal Cancer Survival in a Prospective Cohort of Older Women
Conclusions: Higher tumor infiltration with CTL and GZMB cells is associated with improved all-cause and cancer-specific survival of colorectal cancer patients. Impact: Both the number of CTLs and GZMB appear to be useful prognostic factors in colorectal cancer, irrespective of stage. Cancer Epidemiol Biomarkers Prev; 26(4); 622–31. ©2016 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Prizment, A. E., Vierkant, R. A., Smyrk, T. C., Tillmans, L. S., Nelson, H. H., Lynch, C. F., Pengo, T., Thibodeau, S. N., Church, T. R., Cerhan, J. R., Anderson, K. E., Limburg, P. J. Tags: Research Articles Source Type: research

Long-term Follow-up of Patients Having False-Positive Multitarget Stool DNA Tests after Negative Screening Colonoscopy: The LONG-HAUL Cohort Study
Conclusions: Although FP status was associated with long-term aerodigestive cancers, new cases were not temporally related and did not exceed incidence estimates from general population. Impact: These observations do not justify aggressive follow-up evaluation for patients with FP MT-sDNA at this time. Larger studies are needed to confirm these early findings. Cancer Epidemiol Biomarkers Prev; 26(4); 614–21. ©2016 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Cotter, T. G., Burger, K. N., Devens, M. E., Simonson, J. A., Lowrie, K. L., Heigh, R. I., Mahoney, D. W., Johnson, D. H., Ahlquist, D. A., Kisiel, J. B. Tags: Research Articles Source Type: research

Sun Exposure and Protection Behaviors among Long-term Melanoma Survivors and Population Controls
Conclusions: Although long-term melanoma survivors reported healthier UVR exposure and protection behaviors compared with controls, a sizeable proportion still reported elevated sun exposure, sunburns, and suboptimal UVR protection behaviors. Impact: Opportunities remain for improving sun protection to reduce future melanoma risk among melanoma survivors. Cancer Epidemiol Biomarkers Prev; 26(4); 607–13. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Vogel, R. I., Strayer, L. G., Engelman, L., Nelson, H. H., Blaes, A. H., Anderson, K. E., Lazovich, D. Tags: Research Articles Source Type: research

Body Size Indicators and Risk of Gallbladder Cancer: Pooled Analysis of Individual-Level Data from 19 Prospective Cohort Studies
Conclusions: These findings indicate that measures of overall and central excess body weight are associated with higher gallbladder cancer risks. Impact: Excess body weight is an important, and potentially preventable, gallbladder cancer risk factor. Cancer Epidemiol Biomarkers Prev; 26(4); 597–606. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Campbell, P. T., Newton, C. C., Kitahara, C. M., Patel, A. V., Hartge, P., Koshiol, J., McGlynn, K. A., Adami, H.-O., Berrington de Gonzalez, A., Beane Freeman, L. E., Bernstein, L., Buring, J. E., Freedman, N. D., Gao, Y.-T., Giles, G. G., Gunter, M. J., Tags: Research Articles Source Type: research

Stomach Cancer Disparity among Korean Americans by Tumor Characteristics: Comparison with Non-Hispanic Whites, Japanese Americans, South Koreans, and Japanese
Conclusions: Stomach cancer incidence declined in the highest risk ethnic groups. However, the persistent disparity between Korean Americans and other racial-ethnic groups warrants additional strategies for prevention and earlier diagnosis. Impact: Analysis of California Cancer Registry data identified a racial-ethnic subgroup with stomach cancer disparity that may benefit from targeted prevention and screening efforts. Cancer Epidemiol Biomarkers Prev; 26(4); 587–96. ©2016 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Lee, E., Liu, L., Zhang, J., Stern, M. C., Barzi, A., Hwang, A., Kim, A. E., Hamilton, A. S., Wu, A. H., Deapen, D. Tags: Cancer Surveillance Research Source Type: research

Exploring the Linkage between Activity-Friendly Zoning, Inactivity, and Cancer Incidence in the United States
Conclusions: Zoning can help to create activity-friendly environments that support decreased inactivity, and possibly reduced cancer incidence. Impact: Given low physical activity levels nationwide, cross-sectoral collaborations with urban planning can inform cancer prevention and public health efforts to decrease inactivity and cancer. Cancer Epidemiol Biomarkers Prev; 26(4); 578–86. ©2017 AACR. See all the articles in this CEBP Focus section, "Geospatial Approaches to Cancer Control and Population Sciences." (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Nicholson, L. M., Leider, J., Chriqui, J. F. Tags: CEBP Focus: Geospatial Approaches to Cancer Control and Population Sciences Source Type: research

Spatial Analysis of Regional Factors and Lung Cancer Mortality in China, 1973-2013
Conclusions: The geographic pattern of high LCM in China is different from that of Western countries. LCM is positively associated with higher socioeconomic status, with more urbanized areas at a higher level of industrial development. Impact: There is a need to further explore additional risk in the high-risk clusters. The study is about China, but this situation may happen in other countries experiencing rapid industrialization and other developing countries. Cancer Epidemiol Biomarkers Prev; 26(4); 569–77. ©2017 AACR. See all the articles in this CEBP Focus section, "Geospatial Approaches to Cancer Control an...
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Shen, X., Wang, L., Zhu, L. Tags: CEBP Focus: Geospatial Approaches to Cancer Control and Population Sciences Source Type: research

Housing Discrimination, Residential Racial Segregation, and Colorectal Cancer Survival in Southeastern Wisconsin
Conclusions: Our findings indicate that black women in particular experience poorer colorectal cancer survival in neighborhoods characterized by racial bias in mortgage lending, a measure of institutional racism. These findings are in line with previous studies of breast cancer survival. Impact: Housing discrimination and institutional racism may be important targets for policy change to reduce health disparities, including cancer disparities. Cancer Epidemiol Biomarkers Prev; 26(4); 561–8. ©2017 AACR. See all the articles in this CEBP Focus section, "Geospatial Approaches to Cancer Control and Population Scienc...
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Zhou, Y., Bemanian, A., Beyer, K. M. M. Tags: CEBP Focus: Geospatial Approaches to Cancer Control and Population Sciences Source Type: research

Telomere Length and Neighborhood Circumstances: Evaluating Biological Response to Unfavorable Exposures
Conclusions: Findings support the use of nonlinear statistical methods in TL research and suggest that neighborhood exposures can result in biological effects. Impact: TL may serve as an underlying example of a biologic mechanism that can link neighborhood with biology, thus supporting multilevel investigations in future studies. Cancer Epidemiol Biomarkers Prev; 26(4); 553–60. ©2017 AACR. See all the articles in this CEBP Focus section, "Geospatial Approaches to Cancer Control and Population Sciences." (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Lynch, S. M., Mitra, N., Ravichandran, K., Mitchell, J., Spangler, E., Zhou, W., Paskett, E. D., Gehlert, S., DeGraffinreid, C., Stowe, R., Dubowitz, T., Riethman, H., Branas, C. C., Peek, M. K., Rebbeck, T. R. Tags: CEBP Focus: Geospatial Approaches to Cancer Control and Population Sciences Source Type: research

Racial/Ethnic Differences in the Impact of Neighborhood Social and Built Environment on Breast Cancer Risk: The Neighborhoods and Breast Cancer Study
Conclusions: Our study provides empirical evidence for a role of neighborhood environments in breast cancer risk, specifically social and built environment attributes. Impact: Considering the role of neighborhood characteristics among diverse populations may offer insights to understand racial/ethnic disparities in breast cancer risk. Cancer Epidemiol Biomarkers Prev; 26(4); 541–52. ©2017 AACR. (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Conroy, S. M., Shariff-Marco, S., Koo, J., Yang, J., Keegan, T. H. M., Sangaramoorthy, M., Hertz, A., Nelson, D. O., Cockburn, M., Satariano, W. A., Yen, I. H., Ponce, N. A., John, E. M., Gomez, S. L. Tags: CEBP Focus: Geospatial Approaches to Cancer Control and Population Sciences Source Type: research

A Population-Based Study of Sociodemographic and Geographic Variation in HPV Vaccination
Conclusions: HPV vaccination rates varied geographically and by individual and geographically indexed sociodemographic characteristics. Impact: Identifying geographic regions with low HPV vaccination rates can help target clinical and community efforts to improve vaccination rates. Cancer Epidemiol Biomarkers Prev; 26(4); 533–40. ©2017 AACR. See all the articles in this CEBP Focus section, "Geospatial Approaches to Cancer Control and Population Sciences." (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Finney Rutten, L. J., Wilson, P. M., Jacobson, D. J., Agunwamba, A. A., Radecki Breitkopf, C., Jacobson, R. M., St. Sauver, J. L. Tags: CEBP Focus: Geospatial Approaches to Cancer Control and Population Sciences Source Type: research

GPS-Based Exposure to Greenness and Walkability and Accelerometry-Based Physical Activity
Conclusions: Our results indicate that higher levels of physical activity occurred in areas with higher greenness and higher walkability. Impact: Findings suggest that planning and design policies should focus on these environments to optimize opportunities for physical activity. Cancer Epidemiol Biomarkers Prev; 26(4); 525–32. ©2017 AACR. See all the articles in this CEBP Focus section, "Geospatial Approaches to Cancer Control and Population Sciences." (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: James, P., Hart, J. E., Hipp, J. A., Mitchell, J. A., Kerr, J., Hurvitz, P. M., Glanz, K., Laden, F. Tags: CEBP Focus: Geospatial Approaches to Cancer Control and Population Sciences Source Type: research

Measures Matter: The Local Exposure/Isolation (LEx/Is) Metrics and Relationships between Local-Level Segregation and Breast Cancer Survival
Conclusions: Local segregation is associated with breast cancer survival, but associations varied based on patient race and metric employed. Impact: We highlight how selection of a segregation measure can alter study findings. These relationships need to be validated in other geographic areas. Cancer Epidemiol Biomarkers Prev; 26(4); 516–24. ©2017 AACR. See all the articles in this CEBP Focus section, "Geospatial Approaches to Cancer Control and Population Sciences." (Source: Cancer Epidemiology Biomarkers and Prevention)
Source: Cancer Epidemiology Biomarkers and Prevention - April 2, 2017 Category: Cancer & Oncology Authors: Bemanian, A., Beyer, K. M. M. Tags: CEBP Focus: Geospatial Approaches to Cancer Control and Population Sciences Source Type: research