The critical role of EBUS ‐TBNA cytology in the staging of mediastinal lymph nodes in lung cancer patients: A correlation study with positron emission tomography findings
CONCLUSIONSThe data demonstrate that EBUS‐TBNA cytology improves the diagnostic accuracy of mediastinal LNs and clinical staging. Furthermore, EBUS‐TBNA may identify additional malignant LNs (7.4%), and this highlights the risk for false‐negative findings with PET scanning in isolation. Cancer (Cancer Cytopathol) 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 1, 2017 Category: Pathology Authors: Mohammed T. Lilo, Derek B. Allison, Bouchra K. Younes, Min Cui, Fred B. Askin, Edward Gabrielson, Qing Kay Li Tags: Original Article Source Type: research
A case for German engineering?
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 15, 2017 Category: Pathology Authors: Bryn Nelson Tags: CytoSource Source Type: research
Issue Information
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 15, 2017 Category: Pathology Tags: Issue Information Source Type: research
Consistency and reproducibility of next ‐generation sequencing and other multigene mutational assays: A worldwide ring trial study on quantitative cytological molecular reference specimens
CONCLUSIONSQuantitative molecular reference slides are a useful tool for monitoring the performance of different multigene mutational assays, and this could lead to better standardization of molecular cytopathology procedures. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 5, 2017 Category: Pathology Authors: Umberto Malapelle, Clara Mayo ‐de‐Las‐Casas, Miguel A. Molina‐Vila, Rafael Rosell, Spasenija Savic, Michel Bihl, Lukas Bubendorf, Manuel Salto‐Tellez, Dario de Biase, Giovanni Tallini, David H. Hwang, Lynette M. Sholl, Rajyalakshmi Luthra, Birgi Tags: Original Article Source Type: research
Programmed cell death ligand 1 as a biomarker in head and neck cancer
The evaluation of programmed cell death ligand 1 has a potential role in the application of immune checkpoint inhibitors for select cancers of the head and neck. See related commentary on pages 000‐000. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 4, 2017 Category: Pathology Authors: Sara I. Pai, William C. Faquin Tags: Commentary Source Type: research
Teaching laboratory management and quality assurance/quality improvement skills in a cytopathology fellowship program
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 1, 2017 Category: Pathology Authors: Fang Fan Tags: Bridging the Gap Source Type: research
The role of thyroid FNA cytology in pediatric malignant lesions: An overview of the literature
When one is dealing with pediatric thyroid lesions, fine‐needle aspiration is the first diagnostic tool for the correct characterization of these nodules. Despite the apparent infrequency of thyroid cancers in children, recent data from the National Cancer Institute prove that the incidence has been increasing, especially in adolescents. With the same data, a higher prevalence of well‐differentiated cancers can be estimated, with 90% diagnosed as papillary thyroid cancer. Nonetheless, some publications have demonstrated that some specific malignant variants are more frequent in children and have a more aggressive behav...
Source: Cancer Cytopathology - May 1, 2017 Category: Pathology Authors: Esther Diana Rossi, Maurizio Martini, Tonia Cenci, Sara Capodimonti, Luigi Maria Larocca Tags: Review Article Source Type: research
Performance of Aptima and Cobas HPV testing platforms in detecting high ‐grade cervical dysplasia and cancer
CONCLUSIONSAlthough both the Cobas and Aptima platforms offer highly sensitive tests for high‐grade cervical lesions, Aptima HPV testing demonstrated significantly higher specificity and positive predictive value than Cobas testing for biopsy‐confirmed ≥HSIL. The considerable difference may be related to the significant increase in E6/E7 expression after HPV DNA integration. The significantly higher specificity and overall accuracy of Aptima testing for ≥HSIL, resulting in the identification of high‐risk populations that require immediate treatment and close follow‐up, may prove useful in clinical risk stratifi...
Source: Cancer Cytopathology - May 1, 2017 Category: Pathology Authors: Yimin Ge, Paul Christensen, Eric Luna, Donna Armylagos, Mary R. Schwartz, Dina R. Mody Tags: Original Article Source Type: research
Comparison of glass slides and various digital ‐slide modalities for cytopathology screening and interpretation
CONCLUSIONSThe Aperio whole‐slide scanner with 1 z‐plane scanning and the Panoptiq imaging system with z‐stacking are both suitable for cytopathology screening and interpretation. However, ROI z‐stacks do offer a superior mechanism for overcoming focusing problems commonly encountered with digital cytology slides. Unlike whole‐slide imaging, the acquisition of representative z‐stack images with the Panoptiq system requires a trained cytologist to create digital files. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 1, 2017 Category: Pathology Authors: Matthew G. Hanna, Sara E. Monaco, Jacqueline Cuda, Juan Xing, Ishtiaque Ahmed, Liron Pantanowitz Tags: Original Article Source Type: research
The impact of noninvasive follicular thyroid neoplasm with papillary ‐like nuclear features on the performance of the Afirma gene expression classifier
CONCLUSIONSReclassification of NIFTP significantly decreases the positive predictive value of GEC in indeterminate thyroid nodules. Nevertheless, the majority of patients with indeterminate thyroid nodules with a suspicious GEC result in the study institution have undergone total thyroidectomy. This finding raises concerns over reliance on a suspicious GEC result by clinicians to justify total thyroidectomy. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 1, 2017 Category: Pathology Authors: Jen ‐Fan Hang, William H. Westra, David S. Cooper, Syed Z. Ali Tags: Original Article Source Type: research
“…That which we call a Rose…”: A critical analysis of rapid on‐site evaluation
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 24, 2017 Category: Pathology Authors: Britt ‐Marie Ljung, Joshua R. Menke Tags: Correspondence Source Type: research
Our 2016 Cancer Cytopathology Young Investigator
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 13, 2017 Category: Pathology Authors: Celeste N. Powers Tags: A Note from the Editor Source Type: research
Regulatory roulette
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 13, 2017 Category: Pathology Authors: Bryn Nelson Tags: CytoSource Source Type: research
Issue Information
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 13, 2017 Category: Pathology Tags: Issue Information Source Type: research
p16/Ki ‐67 dual labeling and urinary cytology results according to the New Paris System for Reporting Urinary Cytology: Impact of extended follow‐up
CONCLUSIONSA long‐term evaluation of p16/Ki‐67 dual labeling may identify HGUC and progression in cases with negative/low‐grade urinary cytology results, and there are potential implications for the clinical management of patients after the conservative treatment of non–muscle‐invasive urothelial carcinoma. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 3, 2017 Category: Pathology Authors: Eric Piaton, Anne ‐Sophie Advenier, Christian Carré, Myriam Decaussin‐Petrucci, Florence Mège‐Lechevallier, Karine Hutin, Cindy Nennig, Marc Colombel, Alain Ruffion Tags: Original Article Source Type: research
