The safety, feasibility and oncological outcomes of laparoscopic completion total gastrectomy for remnant gastric cancer: a prospective study with 3-year follow-up (FUGES-004 study)
CONCLUSIONS: This prospective study suggested that LCTG was non-inferior to OCTG in both short- and long-term outcomes. In experienced centers, LCTG may be considered as a viable treatment option for RGC.PMID:38597388 | DOI:10.1097/JS9.0000000000001388 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Qing Zhong Dong Wu Yiming Jiang Qing-Liang He Xue-Yi Dang Dong-Bo Xu Yuqin Sun Guo-Qiang Su Kai-Qing Guo Li-Sheng Cai Haoxiang Zhang Wen Ye Guangtan Lin Ping Li Jian-Wei Xie Qi-Yue Chen Chao-Hui Zheng Jun Lu Chang-Ming Huang Jian-Xian Lin Source Type: research
KIS counteracts PTBP2 and regulates alternative exon usage in neurons
Elife. 2024 Apr 10;13:e96048. doi: 10.7554/eLife.96048. Online ahead of print.ABSTRACTAlternative RNA splicing is an essential and dynamic process in neuronal differentiation and synapse maturation, and dysregulation of this process has been associated with neurodegenerative diseases. Recent studies have revealed the importance of RNA-binding proteins in the regulation of neuronal splicing programs. However, the molecular mechanisms involved in the control of these splicing regulators are still unclear. Here we show that KIS, a kinase upregulated in the developmental brain, imposes a genome-wide alteration in exon usage du...
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Marcos Moreno-Aguilera Alba M Neher M ónica B Mendoza Martin Dodel Faraz K Mardakheh Ra úl Ortiz Carme Gallego Source Type: research
Thermal ablation with and without adjuvant systemic therapy: a nationwide multicenter observational cohort study of solitary colorectal liver metastases
CONCLUSIONS: For patients with plasma CEA >5 ug/L, T (III-IV) category of primary cancer, or clinical risk score (1-2), thermal ablation plus systemic therapy appeared to be associated with improved overall survival. Thermal ablation was equally effective in disease-free survival for treating solitary colorectal liver metastasis, whether with or without adjuvant systemic therapy.PMID:38597399 | DOI:10.1097/JS9.0000000000001397 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Jianming Li Chuan Pang Guangjian Liu Xiaoyan Xie De-Zhi Zhang Kai Li Zhishuai Li Guangbin He Erjiao Xu Huage Zhong Hong Yang Man Lu Kexin Lou Xiang Xie Sirong Lan Qian Li Guanghai Dai Jie Yu Ping Liang Source Type: research
Lung-protective effect of esketamine combined with distal limb ischemic preconditioning in elderly patients undergoing thoracoscopic radical surgery for lung cancer: a randomized controlled trial in 160 cases
CONCLUSION: In elderly patients undergoing thoracoscopic radical surgery for lung cancer, treatment with esketamine combined with LIP can alleviate acute lung injury by enhancing anti-inflammatory response to shorten postoperative hospital stay, reduce lung complications and promote the patients' recovery.PMID:38597439 | DOI:10.12122/j.issn.1673-4254.2024.03.09 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Y Yang G Liu Y Ou W Lu Source Type: research
Association between obesity and cancer risk in HIV-infected Asians
CONCLUSIONS: Obesity, which is one of the important health concerns in HIV management, was associated with an increased risk of non-AIDS-defining cancer but not AIDS-defining cancer.PMID:38597513 | DOI:10.1097/QAD.0000000000003904 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Yoonyoung Jang Taehwa Kim Yunsu Choi Kyoung Hwan Ahn Jung Ho Kim Hye Seong Youn Jeong Kim Shin-Woo Kim Jun Yong Choi Hyo Youl Kim Joon Young Song Hee Jung Choi Sang Il Kim Jang Wook Sohn BumSik Chin Bo-Youl Choi Boyoung Park Source Type: research
Facile and Rapid Microcontact Printing of Additive-Free Polydimethylsiloxane for Biological Patterning Diversity
ACS Appl Mater Interfaces. 2024 Apr 10. doi: 10.1021/acsami.4c00460. Online ahead of print.ABSTRACTThe development and application of micropatterning technology play a promising role in the manipulation of biological substances and the exploration of life sciences at the microscale. However, the universally adaptable micropatterning method with user-friendly properties for acceptance in routine laboratories remains scarce. Herein, a green, facile, and rapid microcontact printing method is reported for upgrading popularization and diversification of biological patterning. The three-step printing can achieve high simplicity ...
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Meilin Sun Jinwei Zhang Tingting Xuanyuan Xufang Liu Wenming Liu Source Type: research
The epigenetic landscape in intestinal stem cells and its deregulation in colorectal cancer
Stem Cells. 2024 Apr 10:sxae027. doi: 10.1093/stmcls/sxae027. Online ahead of print.ABSTRACTEpigenetic mechanisms play a pivotal role in controlling gene expression and cellular plasticity in both normal physiology and pathophysiological conditions. These mechanisms are particularly important in the regulation of stem cell self-renewal and differentiation, both in embryonic development and within adult tissues. A prime example of this finely tuned epigenetic control is observed in the gastrointestinal lining, where the small intestine undergoes renewal approximately every 3-5 days. How various epigenetic mechanisms modulat...
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Axelle Larue Yaser Atlasi Source Type: research
"Decoding inflammation: glycoprotein a repetition predominant, microRNA-142-3-p, and metastasis associated lung adenocarcinoma transcript 1: as novel inflammatory biomarkers of inflammatory bowel disease"
CONCLUSIONS: Dysregulation of GARP, MALAT1, and miR-142-3p likely contributes to inflammation in IBD by reducing TGF-β. MALAT1 is linked to smoking and age-related changes. These genes have potential as diagnostic markers or therapeutic targets for personalized IBD treatment.PMID:38598005 | DOI:10.1007/s11033-024-09475-9 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Mohammad Reza Lahimchi Mousa Mohammadnia-Afrouzi Rasoul Baharlou Dariush Haghmorad Seyed Hassan Abedi Delaram Arjmandi Masoomeh Hosseini Bahman Yousefi Source Type: research
Effect of RARC-ERAS nursing program on clinical outcomes in patients undergoing RARC surgery: a retrospective, propensity matching study
J Robot Surg. 2024 Apr 10;18(1):170. doi: 10.1007/s11701-024-01931-9.ABSTRACTCurrently, there is no specific perioperative nursing standard for RARC based on the ERAS concept. This retrospective study investigates to analyze the effect of RARC-ERAS nursing program on VTE and other clinical outcomes in patients undergoing RARC surgery. This retrospective study included 216 patients undergoing RARC surgery From January 1, 2022 to December 30, 2023, and propensity score adjustment analysis was applied. The study compares a control group receiving traditional nursing and an observation group receiving RARC-ERAS nursing program...
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Mang-Mang He Zhen-Feng Zhou Xiao-Fen Yu Chun-Cong Zhou Source Type: research
Gastric Cancer Mesenchymal Stem Cells Trigger Endothelial Cell Functional Changes to Promote Cancer Progression
In conclusion, GCMSCs may exert regulatory control over Slit2 expression in ECs via the AKT signaling pathway, thereby inducing functional changes in ECs that promote tumor progression.PMID:38598065 | DOI:10.1007/s12015-024-10720-8 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Linjing Cui Ting Liu Chao Huang Fumeng Yang Liqi Luo Li Sun Yuanyuan Zhao Deqiang Wang Mei Wang Yong Ji Wei Zhu Source Type: research
Gamma knife radiosurgery for clival metastasis: case series and systematic review
CONCLUSION: Clival metastasis is rare and associated with poor prognosis. GKRS is a safe, effective treatment for clival metastasis.PMID:38598088 | DOI:10.1007/s11060-024-04648-9 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Sakibul Huq Regan M Shanahan Samuel Adida Othman Bin-Alamer Hussam Abou-Al-Shaar Ajay Niranjan Constantinos G Hadjipanayis L Dade Lunsford Source Type: research
Exposure assessment and risk characterisation of aflatoxins in randomly collected rice samples from local markets of Hyderabad, India
This study revealed an adverse health risk to population of Hyderabad due to consumption of AF contaminated rice.PMID:38598120 | DOI:10.1080/19440049.2024.2339369 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Vakdevi Validandi Srinivasu Kurella Sumitra Gorain Yamuna Sagubandi Sathish Kumar Mungamuri Sukesh Narayan Sinha Source Type: research
Combined supplementation with hesperidin, phytosterols and curcumin decreases adiposity and improves metabolic health in ovariectomized rats
Food Funct. 2024 Apr 10. doi: 10.1039/d3fo05122f. Online ahead of print.ABSTRACTIn recent years many women have looked for alternative therapies to address menopause. Hesperidin, phytosterols and curcumin are bioactive compounds that can ameliorate some cardiovascular risk factors associated with menopause, although there are no data concerning the effects of their combined supplementation. We used ovariectomized (OVX) rats, a postmenopausal model with oestrogen deficiency, to evaluate whether supplementation with a multi-ingredient (MI) including hesperidin, phytosterols and curcumin for 57 days would display beneficial e...
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Julio Baudin Julia Hernandez-Baixauli Sergio Quesada-V ázquez Francisca Mulero Francesc Puiggr òs Llu ís Arola Antoni Caimari Source Type: research
Penile cancer with perineural invasion is more prone to postoperative recurrence
CONCLUSION: Penile cancer with perineural invasion is more prone to and perineural invasion is an independent risk factor for postoperative recurrence of the malignancy.PMID:38598218 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Yue-Fu Han Xin-Hua Yao Ji-Wang Deng Bin Lai Yong-Mao Zeng Lian Peng Zi-Jian Tang Chen Wang Jun-Wei Li Source Type: research
Extracorporeal Shockwave for Intermittent Claudication and Quality of Life: A Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: To our knowledge, this is the first double-blind, placebo-controlled, randomized clinical trial to consider extracorporeal shockwave therapy for the management of intermittent claudication. It demonstrated efficacy for walking distances, may have a positive effect on quality of life, and may provide a safe, noninvasive alternative therapy for patients with intermittent claudication.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT02652078.PMID:38598227 | DOI:10.1001/jamasurg.2024.0625 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Paris Cai Sean Pymer Said Ibeggazene Ali Raza Louise Hitchman Ian Chetter George Smith Source Type: research
