Redirecting macrophage function to sustain their “defender” antitumor activity
Publication date: Available online 1 April 2021Source: Cancer CellAuthor(s): Stephanie L. Tzetzo, Scott I. Abrams (Source: Cancer Cell)
Source: Cancer Cell - April 3, 2021 Category: Cancer & Oncology Source Type: research

Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver
Publication date: Available online 1 April 2021Source: Cancer CellAuthor(s): Alice Bertocchi, Sara Carloni, Paola Simona Ravenda, Giovanni Bertalot, Ilaria Spadoni, Antonino Lo Cascio, Sara Gandini, Michela Lizier, Daniele Braga, Francesco Asnicar, Nicola Segata, Chris Klaver, Paola Brescia, Elio Rossi, Achille Anselmo, Silvia Guglietta, Annalisa Maroli, Paola Spaggiari, Noelia Tarazona, Andres Cervantes (Source: Cancer Cell)
Source: Cancer Cell - April 3, 2021 Category: Cancer & Oncology Source Type: research

More reliable breast cancer risk assessment for every woman
Publication date: Available online 18 March 2021Source: Cancer CellAuthor(s): Han Liang (Source: Cancer Cell)
Source: Cancer Cell - March 31, 2021 Category: Cancer & Oncology Source Type: research

Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
Publication date: Available online 18 March 2021Source: Cancer CellAuthor(s): Hua Su, Fei Yang, Rao Fu, Xin Li, Randall French, Evangeline Mose, Xiaohong Pu, Brittney Trinh, Avi Kumar, Junlai Liu, Laura Antonucci, Jelena Todoric, Yuan Liu, Yinling Hu, Maria T. Diaz-Meco, Jorge Moscat, Christian M. Metallo, Andrew M. Lowy, Beicheng Sun, Michael Karin (Source: Cancer Cell)
Source: Cancer Cell - March 20, 2021 Category: Cancer & Oncology Source Type: research

Size matters: toward reliable breast cancer risk assessment for every woman
Publication date: Available online 18 March 2021Source: Cancer CellAuthor(s): Han Liang (Source: Cancer Cell)
Source: Cancer Cell - March 20, 2021 Category: Cancer & Oncology Source Type: research

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma
Publication date: Available online 11 March 2021Source: Cancer CellAuthor(s): Kevin Bi, Meng Xiao He, Ziad Bakouny, Abhay Kanodia, Sara Napolitano, Jingyi Wu, Grace Grimaldi, David A. Braun, Michael S. Cuoco, Angie Mayorga, Laura DelloStritto, Gabrielle Bouchard, John Steinharter, Alok K. Tewari, Natalie I. Vokes, Erin Shannon, Maxine Sun, Jihye Park, Steven L. Chang, Bradley A. McGregor (Source: Cancer Cell)
Source: Cancer Cell - March 13, 2021 Category: Cancer & Oncology Source Type: research

Progressive immune dysfunction with advancing disease stage in renal cell carcinoma
Publication date: Available online 11 March 2021Source: Cancer CellAuthor(s): David A. Braun, Kelly Street, Kelly P. Burke, David L. Cookmeyer, Thomas Denize, Christina B. Pedersen, Satyen H. Gohil, Nicholas Schindler, Lucas Pomerance, Laure Hirsch, Ziad Bakouny, Yue Hou, Juliet Forman, Teddy Huang, Shuqiang Li, Ang Cui, Derin B. Keskin, John Steinharter, Gabrielle Bouchard, Maxine Sun (Source: Cancer Cell)
Source: Cancer Cell - March 13, 2021 Category: Cancer & Oncology Source Type: research

Pancreatic cancer is suppressed by fibroblast-derived collagen I
Publication date: Available online 11 March 2021Source: Cancer CellAuthor(s): Chris D. Madsen (Source: Cancer Cell)
Source: Cancer Cell - March 13, 2021 Category: Cancer & Oncology Source Type: research

Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression
Publication date: 8 March 2021Source: Cancer Cell, Volume 39, Issue 3Author(s): Taoyong Chen, Mingjin Yang, Zhou Yu, Songqing Tang, Chen Wang, Xuhui Zhu, Jun Guo, Nan Li, Weiping Zhang, Jin Hou, Haibo Liu, Chaofeng Han, Qiuyan Liu, Yan Gu, Cheng Qian, Tao Wan, Long Cui, Minghua Zhu, Weiqiang Zheng, Xuetao Cao (Source: Cancer Cell)
Source: Cancer Cell - March 9, 2021 Category: Cancer & Oncology Source Type: research

A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation
Publication date: 8 March 2021Source: Cancer Cell, Volume 39, Issue 3Author(s): Gregory Lazarian, Shanye Yin, Elisa ten Hacken, Tomasz Sewastianik, Mohamed Uduman, Alba Font-Tello, Satyen H. Gohil, Shuqiang Li, Ekaterina Kim, Heather Joyal, Leah Billington, Elizabeth Witten, Mei Zheng, Teddy Huang, Mariano Severgnini, Valerie Lefebvre, Laura Z. Rassenti, Catherine Gutierrez, Katia Georgopoulos, Christopher J. Ott (Source: Cancer Cell)
Source: Cancer Cell - March 9, 2021 Category: Cancer & Oncology Source Type: research

A gene expression signature associated with ‘‘K-Ras addiction’’ reveals regulators of EMT and tumor cell survival
Publication date: 8 March 2021Source: Cancer Cell, Volume 39, Issue 3Author(s): Anurag Singh, Patricia Greninger, Daniel Rhodes, Louise Koopman, Sheila Violette, Nabeel Bardeesy, Jeff Settleman (Source: Cancer Cell)
Source: Cancer Cell - March 9, 2021 Category: Cancer & Oncology Source Type: research

Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
Publication date: Available online 4 March 2021Source: Cancer CellAuthor(s): Yang Chen, Jiha Kim, Sujuan Yang, Huamin Wang, Chang-Jiun Wu, Hikaru Sugimoto, Valerie S. LeBleu, Raghu Kalluri (Source: Cancer Cell)
Source: Cancer Cell - March 5, 2021 Category: Cancer & Oncology Source Type: research

MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
Publication date: Available online 4 March 2021Source: Cancer CellAuthor(s): Koki Ueda, Rajni Kumari, Emily Schwenger, Justin C. Wheat, Oliver Bohorquez, Swathi-Rao Narayanagari, Samuel J. Taylor, Luis A. Carvajal, Kith Pradhan, Boris Bartholdy, Tihomira I. Todorova, Hiroki Goto, Daqian Sun, Jiahao Chen, Jidong Shan, Yinghui Song, Cristina Montagna, Shunbin Xiong, Guillermina Lozano, Andrea Pellagatti (Source: Cancer Cell)
Source: Cancer Cell - March 5, 2021 Category: Cancer & Oncology Source Type: research

The human leukocyte antigen as a candidate tumor suppressor
Publication date: Available online 18 February 2021Source: Cancer CellAuthor(s): Elisabet Pujadas, Carlos Cordon-Cardo (Source: Cancer Cell)
Source: Cancer Cell - February 19, 2021 Category: Cancer & Oncology Source Type: research

Multi-cancer early detection: a new paradigm for reducing cancer-specific and all-cause mortality
Publication date: Available online 18 February 2021Source: Cancer CellAuthor(s): Christina A. Clarke, Earl Hubbell, Joshua J. Ofman (Source: Cancer Cell)
Source: Cancer Cell - February 19, 2021 Category: Cancer & Oncology Source Type: research