Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
Publication date: 14 June 2021Source: Cancer Cell, Volume 39, Issue 6Author(s): Silvia Affo, Ajay Nair, Francesco Brundu, Aashreya Ravichandra, Sonakshi Bhattacharjee, Michitaka Matsuda, LiKang Chin, Aveline Filliol, Wen Wen, Xinhua Song, Aubrianna Decker, Jeremy Worley, Jorge Matias Caviglia, Lexing Yu, Deqi Yin, Yoshinobu Saito, Thomas Savage, Rebecca G. Wells, Matthias Mack, Lars Zender (Source: Cancer Cell)
Source: Cancer Cell - June 15, 2021 Category: Cancer & Oncology Source Type: research

Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity
Publication date: Available online 10 June 2021Source: Cancer CellAuthor(s): Andrew Chow, Sara Schad, Michael D. Green, Matthew D. Hellmann, Viola Allaj, Nicholas Ceglia, Giulia Zago, Nisargbhai S. Shah, Sai Kiran Sharma, Marissa Mattar, Joseph Chan, Hira Rizvi, Hong Zhong, Cailian Liu, Yonina Bykov, Dmitriy Zamarin, Hongyu Shi, Sadna Budhu, Corrin Wohlhieter, Fathema Uddin (Source: Cancer Cell)
Source: Cancer Cell - June 11, 2021 Category: Cancer & Oncology Source Type: research

Developing and validating model systems for immuno-oncology
Publication date: Available online 10 June 2021Source: Cancer CellAuthor(s): Claire E. McCarthy, Nastaran Zahir, Mariam Eljanne, Elad Sharon, Emile E. Voest, Karolina Palucka (Source: Cancer Cell)
Source: Cancer Cell - June 11, 2021 Category: Cancer & Oncology Source Type: research

Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states
Publication date: Available online 10 June 2021Source: Cancer CellAuthor(s): Kamen P. Simeonov, China N. Byrns, Megan L. Clark, Robert J. Norgard, Beth Martin, Ben Z. Stanger, Jay Shendure, Aaron McKenna, Christopher J. Lengner (Source: Cancer Cell)
Source: Cancer Cell - June 11, 2021 Category: Cancer & Oncology Source Type: research

Seroconversion rates following COVID-19 vaccination amongst patients with cancer
Publication date: Available online 5 June 2021Source: Cancer CellAuthor(s): Astha Thakkar, Jesus D. Gonzalez-Lugo, Niyati Goradia, Radhika Gali, Lauren C. Shapiro, Kith Pradhan, Shafia Rahman, So Yeon Kim, Brian Ko, R. Alejandro Sica, Noah Kornblum, Lizamarie Bachier-Rodriguez, Margaret McCort, Sanjay Goel, Roman Perez-Soler, Stuart Packer, Joseph Sparano, Benjamin Gartrell, Della Makower, Yitz D. Goldstein (Source: Cancer Cell)
Source: Cancer Cell - June 6, 2021 Category: Cancer & Oncology Source Type: research

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
Publication date: Available online 3 June 2021Source: Cancer CellAuthor(s): Toshiro Hara, Rony Chanoch-Myers, Nathan D. Mathewson, Chad Myskiw, Lyla Atta, Lillian Bussema, Stephen W. Eichhorn, Alissa C. Greenwald, Gabriela S. Kinker, Christopher Rodman, L. Nicolas Gonzalez Castro, Hiroaki Wakimoto, Orit Rozenblatt-Rosen, Xiaowei Zhuang, Jean Fan, Tony Hunter, Inder M. Verma, Kai W. Wucherpfennig, Aviv Regev, Mario L. Suvà (Source: Cancer Cell)
Source: Cancer Cell - June 5, 2021 Category: Cancer & Oncology Source Type: research

Macrophage-tumor cell intertwine drives the transition into a mesenchymal-like cellular state of glioblastoma
Publication date: Available online 3 June 2021Source: Cancer CellAuthor(s): Zhihong Chen, Dolores Hambardzumyan (Source: Cancer Cell)
Source: Cancer Cell - June 5, 2021 Category: Cancer & Oncology Source Type: research

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation
Publication date: Available online 27 May 2021Source: Cancer CellAuthor(s): Yuanming Cheng, Wei Xie, Brian F. Pickering, Karen L. Chu, Angela M. Savino, Xuejing Yang, Hanzhi Luo, Diu TT. Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas M. Rohwetter, Dinshaw J. Patel, Samie R. Jaffrey, Michael G. Kharas (Source: Cancer Cell)
Source: Cancer Cell - May 28, 2021 Category: Cancer & Oncology Source Type: research

Conserved pan-cancer microenvironment subtypes predict response to immunotherapy
Publication date: Available online 20 May 2021Source: Cancer CellAuthor(s): Alexander Bagaev, Nikita Kotlov, Krystle Nomie, Viktor Svekolkin, Azamat Gafurov, Olga Isaeva, Nikita Osokin, Ivan Kozlov, Felix Frenkel, Olga Gancharova, Nava Almog, Maria Tsiper, Ravshan Ataullakhanov, Nathan Fowler (Source: Cancer Cell)
Source: Cancer Cell - May 21, 2021 Category: Cancer & Oncology Source Type: research

Precision oncology: Directing genomics and pharmacogenomics toward reducing cancer inequities
Publication date: Available online 20 May 2021Source: Cancer CellAuthor(s): Loren Saulsberry, Olufunmilayo I. Olopade (Source: Cancer Cell)
Source: Cancer Cell - May 21, 2021 Category: Cancer & Oncology Source Type: research

The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth
Publication date: Available online 20 May 2021Source: Cancer CellAuthor(s): Lihui Dong, Chuanyuan Chen, Yawei Zhang, Peijin Guo, Zhenghang Wang, Jian Li, Yi Liu, Jun Liu, Renbao Chang, Yilin Li, Guanghao Liang, Weiyi Lai, Mengxue Sun, Urszula Dougherty, Marc B. Bissonnette, Hailin Wang, Lin Shen, Meng Michelle Xu, Dali Han (Source: Cancer Cell)
Source: Cancer Cell - May 21, 2021 Category: Cancer & Oncology Source Type: research

A tumor “personality” test to guide therapeutic decision making
Publication date: Available online 20 May 2021Source: Cancer CellAuthor(s): Kathleen E. Houlahan, Christina Curtis (Source: Cancer Cell)
Source: Cancer Cell - May 21, 2021 Category: Cancer & Oncology Source Type: research

Interleukin-1 in tumor progression, therapy, and prevention
Publication date: Available online 13 May 2021Source: Cancer CellAuthor(s): Cecilia Garlanda, Alberto Mantovani (Source: Cancer Cell)
Source: Cancer Cell - May 14, 2021 Category: Cancer & Oncology Source Type: research

Translating inspiration from COVID-19 vaccine trials to innovations in clinical cancer research
Publication date: Available online 7 May 2021Source: Cancer CellAuthor(s): Noura J. Choudhury, Gregory J. Riely, Paul J. Sabbatini, Matthew D. Hellmann (Source: Cancer Cell)
Source: Cancer Cell - May 8, 2021 Category: Cancer & Oncology Source Type: research

Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer
Publication date: Available online 6 May 2021Source: Cancer CellAuthor(s): Milena Hornburg, Mélanie Desbois, Shan Lu, Yinghui Guan, Amy A. Lo, Susan Kaufman, Ashley Elrod, Alina Lotstein, Teresa M. DesRochers, Jose L. Munoz-Rodriguez, Xingwei Wang, Jennifer Giltnane, Oleg Mayba, Shannon J. Turley, Richard Bourgon, Anneleen Daemen, Yulei Wang (Source: Cancer Cell)
Source: Cancer Cell - May 7, 2021 Category: Cancer & Oncology Source Type: research