FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer
Publication date: Available online 3 September 2020Source: Cancer CellAuthor(s): Amaia Arruabarrena-Aristorena, Jesper L.V. Maag, Srushti Kittane, Yanyan Cai, Wouter R. Karthaus, Erik Ladewig, Jane Park, Srinivasaraghavan Kannan, Lorenzo Ferrando, Emiliano Cocco, Sik Y. Ho, Daisylyn S. Tan, Mirna Sallaku, Fan Wu, Barbara Acevedo, Pier Selenica, Dara S. Ross, Matthew Witkin, Charles L. Sawyers, Jorge S. Reis-Filho (Source: Cancer Cell)
Source: Cancer Cell - September 5, 2020 Category: Cancer & Oncology Source Type: research

Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies
Publication date: Available online 28 August 2020Source: Cancer CellAuthor(s): Jingwen Si, Xiangjun Shi, Shuhao Sun, Bin Zou, Yaopeng Li, Dongjie An, Xingyu Lin, Yan Gao, Fei Long, Bo Pang, Xing Liu, Tian Liu, Wenna Chi, Ligong Chen, Dimiter S. Dimitrov, Yan Sun, Xinru Du, Wen Yin, Guangxun Gao, Junxia Min (Source: Cancer Cell)
Source: Cancer Cell - August 30, 2020 Category: Cancer & Oncology Source Type: research

Breaking Barriers in HER2+ Cancers
Publication date: Available online 27 August 2020Source: Cancer CellAuthor(s): Salvatore Siena, Silvia Marsoni, Andrea Sartore-Bianchi (Source: Cancer Cell)
Source: Cancer Cell - August 29, 2020 Category: Cancer & Oncology Source Type: research

Mastering the Complex Targeted Therapy for Non-small Cell Lung Cancer
Publication date: Available online 27 August 2020Source: Cancer CellAuthor(s): Siddhartha Devarakonda, Ramaswamy Govindan, Daniel Morgensztern (Source: Cancer Cell)
Source: Cancer Cell - August 29, 2020 Category: Cancer & Oncology Source Type: research

Identifying and Targeting Human Tumor Antigens for T Cell-Based Immunotherapy of Solid Tumors
Publication date: Available online 20 August 2020Source: Cancer CellAuthor(s): Vid Leko, Steven A. Rosenberg (Source: Cancer Cell)
Source: Cancer Cell - August 21, 2020 Category: Cancer & Oncology Source Type: research

Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
Publication date: Available online 13 August 2020Source: Cancer CellAuthor(s): Chan Chung, Stefan R. Sweha, Drew Pratt, Benita Tamrazi, Pooja Panwalkar, Adam Banda, Jill Bayliss, Debra Hawes, Fusheng Yang, Ho-Joon Lee, Mengrou Shan, Marcin Cieslik, Tingting Qin, Christian K. Werner, Daniel R. Wahl, Costas A. Lyssiotis, Zhiguo Bian, J. Brad Shotwell, Viveka Nand Yadav, Carl Koschmann (Source: Cancer Cell)
Source: Cancer Cell - August 14, 2020 Category: Cancer & Oncology Source Type: research

Clinical Challenges of Immune Checkpoint Inhibitors
Publication date: Available online 3 August 2020Source: Cancer CellAuthor(s): Maria de Miguel, Emiliano Calvo (Source: Cancer Cell)
Source: Cancer Cell - August 4, 2020 Category: Cancer & Oncology Source Type: research

Engineering CAR-T Cells for Next-Generation Cancer Therapy
Publication date: Available online 30 July 2020Source: Cancer CellAuthor(s): Mihe Hong, Justin D. Clubb, Yvonne Y. Chen (Source: Cancer Cell)
Source: Cancer Cell - July 31, 2020 Category: Cancer & Oncology Source Type: research

Utility of COVID-19 Screening in Cancer Patients
Publication date: Available online 24 July 2020Source: Cancer CellAuthor(s): Lennard Y.W. Lee, Thomas Hill, Oliver Topping, Michael Tilby, Mark Baker, Julian Greig, Lawrence Isherwood, Robert Miller, Yuriy Petrenko, Ruchi Desai, Alice Field, Bethany Kennedy, Shahbano Khan, Alexandra Kountourou, Sandisile Ndlovu, Thomas Starkey, Francesca Storey, Lucy Turner, William Vaughan-Williams, Surrinder Moyler (Source: Cancer Cell)
Source: Cancer Cell - July 26, 2020 Category: Cancer & Oncology Source Type: research

Cancer Patients and Risk of Mortality for COVID-19
Publication date: Available online 25 July 2020Source: Cancer CellAuthor(s): Giuseppe Curigliano (Source: Cancer Cell)
Source: Cancer Cell - July 26, 2020 Category: Cancer & Oncology Source Type: research

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
Publication date: Available online 23 July 2020Source: Cancer CellAuthor(s): Nemanja Despot Marjanovic, Matan Hofree, Jason E. Chan, David Canner, Katherine Wu, Marianna Trakala, Griffin G. Hartmann, Olivia Smith, Jonathan Kim, Kelly Victoria Evans, Anna Hudson, Orr Ashenberg, Caroline B.M. Porter, Alborz Bejnood, Ayshwarya Subramanian, Kenneth Pitter, Yan Yan, Toni Delroy, Devan R. Phillips, Nisargbhai Shah (Source: Cancer Cell)
Source: Cancer Cell - July 24, 2020 Category: Cancer & Oncology Source Type: research

Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma
Publication date: Available online 23 July 2020Source: Cancer CellAuthor(s): Lindsay M. LaFave, Vinay K. Kartha, Sai Ma, Kevin Meli, Isabella Del Priore, Caleb Lareau, Santiago Naranjo, Peter M.K. Westcott, Fabiana M. Duarte, Venkat Sankar, Zachary Chiang, Alison Brack, Travis Law, Haley Hauck, Annalisa Okimoto, Aviv Regev, Jason D. Buenrostro, Tyler Jacks (Source: Cancer Cell)
Source: Cancer Cell - July 24, 2020 Category: Cancer & Oncology Source Type: research

Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer
Publication date: Available online 16 July 2020Source: Cancer CellAuthor(s): Zeda Zhang, Wouter R. Karthaus, Young Sun Lee, Vianne R. Gao, Chao Wu, Joshua W. Russo, Menghan Liu, Jose Mauricio Mota, Wassim Abida, Eliot Linton, Eugine Lee, Spencer D. Barnes, Hsuan-An Chen, Ninghui Mao, John Wongvipat, Danielle Choi, Xiaoping Chen, Huiyong Zhao, Katia Manova-Todorova, Elisa de Stanchina (Source: Cancer Cell)
Source: Cancer Cell - July 17, 2020 Category: Cancer & Oncology Source Type: research

IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
Publication date: Available online 16 July 2020Source: Cancer CellAuthor(s): Rasmus Siersbæk, Valentina Scabia, Sankari Nagarajan, Igor Chernukhin, Evangelia K. Papachristou, Rebecca Broome, Simon J. Johnston, Stacey E.P. Joosten, Andrew R. Green, Sanjeev Kumar, Julia Jones, Soleilmane Omarjee, Ruben Alvarez-Fernandez, Silvia Glont, Sarah J. Aitken, Kamal Kishore, Danya Cheeseman, Emad A. Rakha, Clive D'Santos, Wilbert Zwart (Source: Cancer Cell)
Source: Cancer Cell - July 17, 2020 Category: Cancer & Oncology Source Type: research

Zena Werb (1945–2020)
Publication date: 13 July 2020Source: Cancer Cell, Volume 38, Issue 1Author(s): Danny R. Welch (Source: Cancer Cell)
Source: Cancer Cell - July 14, 2020 Category: Cancer & Oncology Source Type: research