Untargeted serum metabolomic profiles and breast density in young women
ConclusionOur results suggest an inverse association of branched chain amino acids with %DBV. Larger studies in diverse populations are needed. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 22, 2023 Category: Cancer & Oncology Source Type: research

Prevalence and predictors of colorectal cancer screening in the United States: evidence from the HINTS database 2018 to 2020
ConclusionCRC screening rates among adults 45 –49 years are low but are increasing steadily. Odds of CRC screening among Blacks is high which is encouraging while the odds among current smokers is low and concerning given their increased risk of developing CRC. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 22, 2023 Category: Cancer & Oncology Source Type: research

Compliance with public health recommendations of cancer-free female research volunteers: the French Seintinelles study
ConclusionsThis study allowed to identify the need to increase the level of knowledge on modifiable risk factors for cancer among the general population and to better clarify the content of prevention messages. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 21, 2023 Category: Cancer & Oncology Source Type: research

Household cooking fuel and gallbladder cancer risk: a multi-centre case –control study in India
ConclusionBiomass burning was associated with a high-risk for GBC and should be considered as a modifiable risk factor for GBC. Clean cooking fuel can potentially mitigate, and a healthy diet can partially reduce the risk among women. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 21, 2023 Category: Cancer & Oncology Source Type: research

Optimizing process flow diagrams to guide implementation of a colorectal cancer screening intervention in new settings
ConclusionProcess maps can potentially support decision-making about the adoption, implementation, and adaptation of existing EBIs in new contexts. Given the complexities involved in deciding whether and how to implement EBIs, these diagrams serve as visual, easily understood tools to inform potential future adopters of the EBI about the activities, resources, and staffing needed for implementation. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 21, 2023 Category: Cancer & Oncology Source Type: research

Equitable implementation of lung cancer screening: avoiding its potential to mirror existing inequities among people who use tobacco
ConclusionThe present commentary utilizes information about historical trends in tobacco use to highlight opportunities for targeted outreach efforts to engage communities at high risk with information about the lung cancer screening opportunity. Future efforts toward equitable implementation of lung cancer screening should focus on multi-level implementation strategies that engage and work in concert with community partners to co-create approaches that leverage strengths and reduce barriers within specific communities to achieve the potential of lung cancer screening. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 15, 2023 Category: Cancer & Oncology Source Type: research

Vitamin D and monoclonal gammopathy of undetermined significance (MGUS) among U.S. Black women
ConclusionMGUS was more prevalent among Black women with vitamin D deficiency compared to those with 25(OH)D  ≥ 30 ng/mL; however, the association was not statistically significant. Future prospective studies are warranted to clarify the possible association between vitamin D and MGUS. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 14, 2023 Category: Cancer & Oncology Source Type: research

Latent pathway-based Bayesian models to identify intervenable factors of racial disparities in breast cancer stage at diagnosis
ConclusionsMammography utilization had a significant effect on racial differences in breast cancer stage-at-diagnosis, while tumor biology factors had less impact. Biopsy delay also aided in predicting local and regional stages-at-diagnosis for Black NH women but not for white NH women. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 13, 2023 Category: Cancer & Oncology Source Type: research

Effects of treatment methods on cutaneous melanoma related mortality and all-cause mortality in Texas: TCR-Medicare 2007 –2017 database
ConclusionOur results propose differences in all-cause and CM-only related mortality with separate treatment modalities, particularly with chemotherapy, radiation therapy and immunotherapy. In addition, this retrospective cohort study showed that health disparities exist in the Hispanic Medicare population of Texas with CM. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 13, 2023 Category: Cancer & Oncology Source Type: research

Socioeconomic and geographic disparities of breast cancer incidence according to stage at diagnosis in France
ConclusionAlthough advanced BC was more frequent in women living in deprived and rural areas, SB did not influence advanced BC incidence. Therefore, differences observed in overall BC incidence according to SB were only due to higher incidence of early BC in affluent and urban areas. Future research should confirm these results in other French areas. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 11, 2023 Category: Cancer & Oncology Source Type: research

Racial disparities in colorectal cancer clinicopathological and molecular tumor characteristics: a systematic review
ConclusionHigher rates ofKRAS-mutant tumors in in African Americans may contribute to disparities in CRC mortality. Additional work is required to understand whether emerging markers, including immune cells, underlie the elevated CRC mortality observed for African Americans. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 9, 2023 Category: Cancer & Oncology Source Type: research

Factors associated with adherence to medications for lowering breast cancer risk between female Medicare beneficiaries in Alabama and nationwide
ConclusionOur findings highlight the importance of access to preventive services such as mammography to better adherence to BC preventive treatments among female Medicare beneficiaries. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 8, 2023 Category: Cancer & Oncology Source Type: research

Pectoral muscle removal in mammogram images: A novel approach for improved accuracy and efficiency
ConclusionWe present a novel approach for pectoral muscle removal in mammogram images that demonstrates significant improvement in accuracy and efficiency compared to existing method. Our findings have important implications for the development of computer-aided systems and other automated tools in this field. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 7, 2023 Category: Cancer & Oncology Source Type: research

Nativity differences in socioeconomic barriers and healthcare delays among cancer survivors in the All of Us cohort
ConclusionWe found that SES barriers to healthcare delays have a greater impact among foreign-born than US-born cancer survivors. Higher health literacy may mitigate healthcare delays among US cancer survivors. Healthcare providers, systems and policymakers should assess and address social determinants of health and promote health literacy as a way to minimize healthcare delays among both foreign- and US-born cancer survivors. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - September 7, 2023 Category: Cancer & Oncology Source Type: research

Understanding the burden of colorectal cancer in a three-county rural region of Michigan: an ecological analysis of incidence, mortality, and risk factors
ConclusionFindings suggest that living in Michigan ’s Thumb region is associated with higher CRC incidence and mortality compared to Michigan’s other rural and urban regions, even after controlling for known risk factors. More studies on individual-level demographic, environmental, tumor, and treatment characteristics (e.g., treatment difference s, water quality, pesticide use) are needed to further characterize these findings. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - August 22, 2023 Category: Cancer & Oncology Source Type: research