The special sauce of the Cancer Prevention and Control Research Network: 20  years of lessons learned in developing the evidence base, building community capacity, and translating research into practice
ConclusionCPCRN ’s history highlights organizational, strategic, and practical lessons learned over two decades to optimize Network collaboration for enhanced collective impact in cancer prevention and control. These insights may be useful to others seeking to leverage collaborative networks to address public hea lth problems. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 24, 2023 Category: Cancer & Oncology Source Type: research

Disparities in screening mammography utilization among Hispanic women in rural Texas from 2002 to 2018
ConclusionsOur study demonstrated significant and persistent racial and urban –rural disparities in screening mammography utilization among Hispanic women compared with non-Hispanic white women from 2002 to 2018. Healthcare access is a major contributor to these disparities. It highlights the need for wide-scale interventions from public health and policymakers targeting un der screened racial minorities and rural regions population to promote screening mammography services among disadvantaged population. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 24, 2023 Category: Cancer & Oncology Source Type: research

Risk of colorectal adenocarcinoma in men receiving androgen deprivation therapy for prostate cancer; a nationwide cohort study
ConclusionsThis population-based study found an increased risk of CRC among PC patients exposed to ADT, specifically adenocarcinoma of the distal colon, which indicates an increased association between ADT (PC  + ADT) and CRC but not a positive dose-response trend questioning a true causal effect. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 21, 2023 Category: Cancer & Oncology Source Type: research

Repeated measures of mammographic density and texture to evaluate prediction and risk of breast cancer: a systematic review of the methods used in the literature
ConclusionThis review provided an updated overview and revealed research gaps in assessment of the use of texture features, risk prediction, and AUC. We provide recommendations for future studies using repeated measure methods for mammogram images to improve risk classification and risk prediction for women to tailor screening and prevention strategies to level of risk. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 20, 2023 Category: Cancer & Oncology Source Type: research

Birth characteristics and risk of Ewing sarcoma
ConclusionsThis population-based study with minimal selection bias provides support for a role of accelerated fetal growth in the etiology of Ewing sarcoma in addition to more precise estimates of racial and ethnic variations in disease risk. This comparatively large analysis of birth characteristics and Ewing sarcoma in a multiethnic population should stimulate further investigations into genetic and environmental causes. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 19, 2023 Category: Cancer & Oncology Source Type: research

Diet and lifestyle in relation to small intestinal cancer risk: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)
ConclusionThese exploratory analyses found limited evidence for a role of modifiable risk factors in SIC aetiology. However, sample size was limited, particularly for histologic subtypes; therefore, larger studies are needed to delineate these associations and robustly identify risk factors for SIC. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 18, 2023 Category: Cancer & Oncology Source Type: research

The effect of general practice contact on cancer stage at diagnosis in Aboriginal and non-Aboriginal residents of New South Wales
ConclusionOlder Aboriginal Australians diagnosed with cancer experience more comorbid conditions and more socioeconomic disadvantage than other Australians, which are negatively related to diagnosis at a local-cancer stage. More frequent GP contact may act to partly offset this among the Aboriginal population of NSW. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 17, 2023 Category: Cancer & Oncology Source Type: research

Variation in hysterectomy prevalence and trends among U.S. States and Territories —Behavioral Risk Factor Surveillance System, 2012–2020
ConclusionsApproximately one in five U.S. women overall and half of U.S. women aged  ≥ 70 years reported undergoing a hysterectomy. Our findings reveal large variations in hysterectomy prevalence within and between each of the four census regions and by race and other sociodemographic characteristics, underscoring the importance of adjusting epidemiologic measures of uterine and cervical cancers for hysterectomy status. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 17, 2023 Category: Cancer & Oncology Source Type: research

Supporting implementation science and health equity in cancer prevention and control through research networks
AbstractThe Cancer Prevention and Control Research Network (CPCRN) is a national network of academic, public health, and community organizational partners across multiple geographic sites who collaborate to reduce the cancer burden in diverse communities. Given key recommendations that suggest the need for cross-disciplinary collaboration in cancer prevention and control, we sought to explore the historical and contemporary evolution of health equity and disparities research as an area of focus within the CPCRN over time. We conducted 22 in-depth interviews with former and current leaders, co-investigators, and other membe...
Source: Cancer Causes and Control - June 16, 2023 Category: Cancer & Oncology Source Type: research

Supplement use and gastric cancer risk in the Southern Community Cohort Study
ConclusionRegular supplement use, including multivitamins, was associated with a decreased risk of NCGC in the SCCS, particularly among participants with a lower quality diet. Inverse associations of supplement use and NCGC incidence provide support for clinical trials among high-risk populations in the US. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 13, 2023 Category: Cancer & Oncology Source Type: research

Changes in uptake of stool-based colorectal cancer screening during the Covid-19 pandemic
ConclusionsUse and recommendations for SBS increased substantially during the pandemic. Increased awareness among patients could potentially improve future CRC screening rates if uptake of SBS occurs among those unable or unwilling to be screened by endoscopy. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 13, 2023 Category: Cancer & Oncology Source Type: research

Uptake of colorectal cancer screening after mailed fecal immunochemical test (FIT) outreach in a newly eligible 45 –49-year-old community health center population
ConclusionCRC screening appeared to increase following a mailed FIT intervention among diverse FQHC patients aged 45 –49. Larger studies are needed to assess acceptability and completion of CRC screening in this younger population. Visually appealing mailers may improve uptake when implementing mailed interventions.Trial registration The trial was registered on May 28, 2020 at ClinicalTrials.gov (identifier NCT04406714). (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 10, 2023 Category: Cancer & Oncology Source Type: research

Associations of gut microbiome with endogenous estrogen levels in healthy postmenopausal women
ConclusionMicrobial diversity was associated with several estrogen metabolism ratios implicated in breast cancer risk. Further studies are warranted to confirm these findings in a larger and more representative sample of postmenopausal women, particularly with enrichment of minority participants. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 7, 2023 Category: Cancer & Oncology Source Type: research

Multi-level predictors of being up-to-date with colorectal cancer screening
ConclusionThis study identified 12 individual- and county-level demographic characteristics related to being up-to-date with screening to inform how interventions may optimally be targeted. (Source: Cancer Causes and Control)
Source: Cancer Causes and Control - June 7, 2023 Category: Cancer & Oncology Source Type: research

Lessons to inform interventions to reduce racial and ethnic health disparities within hematologic malignancies
AbstractAlthough racial and ethnic disparities in diagnosis, treatment, and survival have been well documented within the field of hematologic malignancies, very little work has focused on testing interventions that may reduce these disparities. The aim of this commentary is to review prior work in hematologic malignancies and explore new opportunities to develop disparity-reducing interventions by drawing from evidence-based strategies that have been successfully implemented in fields related to hematologic malignancies, including oncology and solid organ transplants. Relevant literature demonstrates that patient navigati...
Source: Cancer Causes and Control - June 7, 2023 Category: Cancer & Oncology Source Type: research