104 - Glucose-Induced Endothelial Oxidative Stress and Accelerated Aging are Mediated by Mitochondrial SIRTs
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Jieting Liu, Biao Feng, Shali Chen, Yanhui Chu, Subrata Chakrabarti (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

105 - A Rare Case of Recurrent Diabetic Muscle Infarction: An Overlooked Complication of Diabetes Mellitus
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Khushpreet Kaur Saini, Saima Manzoor (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

106 - Vigorous Intensity Intervals and Moderate Intensity Exercise Have Similar Postexercise Impacts on Blood Glucose in Trained Young Adults With Type 1 Diabetes
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Andrea Macintosh, Jacqueline L. Hay, Dessi P. Zaharieva, Veronica Jamnik, Michael C. Riddell, Normand G. Boulé, Jonathan M. Mcgavock, Jane E. Yardley (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

107 - Physical Activity and Cardiometabolic Health in Youth With Type 2 Diabetes
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Jana Slaght, Brandy A. Wicklow, Allison B. Dart, Elizabeth Sellers, Jonathan M. Mcgavock, ICARE Investigator Team (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

108 - Tuning Muscle Energy Homeostasis: The Role of Nix Durig Contractile Activity
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Jared T. Field, Matthew D. Martens, Joseph W. Gordon (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

109 - Cost-Effectiveness of a Physician-Delivered Step Count Prescription Strategy
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Tarsan Sangarapillai, Mohammad Hajizadeh, Stella Styliani Daskalopoulou, Kaberi Dasgupta (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

110 - A Trajectory Analysis of Daily Step Counts During a Physician-Delivered Intervention
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Alexandra Cooke, Alvin Kuate-Defo, Debbie Chan, Elham Rahme, Stella Styliani Daskalopoulou, Kaberi Dasgupta (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

111 - Role of Insulin-Like Growth Factor Binding Protein 2 on Podocyte Function and Diabetic Nephropathy
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): David-Alexandre Dancosst, Farah Lizotte, Jonathan M. Mcgavock, Frédéric Picard, Pedro Geraldes (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

112 - eVisits in Endocrinology and Metabolism: Improving Access to Care in a Tertiary Ambulatory Care Clinic
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Janine Malcolm, Shannon Nelson, Annie Garon-Mailer, Amber Mitchell, Kristen RAE, Ellen B. GOLDBLOOM (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

113 - Impact of the Diabetes Canada Guideline Dissemination Strategy on Dispensed Vascular Protective Medications for Older Patients in Ontario, Canada: A Linked EMR and Administrative Study
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Michelle Greiver, Sumeet Kalia, Rahim Moineddin, Simon Chen, Raquel Duchenal, Anna Rigobon (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

114 - Innovations in Providing Diabetes Care for Individuals Experiencing Homelessness: An Environmental Scan
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): David Campbell, Rachel Campbell, Gillian L. Booth, Stephen Hwang, Kerry Mcbrien (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

115 - Conversations and Reactions Around Severe Hypoglycemia (CRASH Study): Canadian Results
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Donna Mojdami, Mark Peyrot, Erik Spaepen, Beatrice Osumili, Zaneta Balantac, Beth Mitchell, Frank Snoek (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

116 - Impaired Awareness of Hypoglycemia Increases Severe Hypoglycemia Rates in T2DM (InHypo-DM Study)
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Alexandria Ratzki-Leewing, Stewart B. Harris, Natalie H. Au, susan webster-bogaert, judith b. Brown, sonja M. Reichert, Bridget L. Ryan (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

117 - Diabetes Duration Did Not Moderate Severe Hypoglycemia Seen With Glargine U100 vs Degludec in DEVOTE
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Vincent Woo, Kajsa Kvist, John B. Buse, Elise Hachmann-Nielsen, Anastasia-Stefania Alexopoulos (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

118 - Potential Functional Foods and Nutraceuticals From Hypoglycemic Compounds Isolated From Eucalyptus Camaldulensis
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Denise Daley, Ruby Alexander-Lindo, Trevor Yee, Paul Reese (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

119 - Real-World Incidence and Risk Indicator of Nonsevere Hypoglycemia in T1DM (InHypo-DM Study)
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Natalie H. Au, Alexandria Ratzki-Leewing, Bridget L. Ryan, Susan Webster-Bogaert, Judith B. Brown, Sonja M. Reichert, Stewart B. Harris (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

120 - Closing the Indigenous Health Gap in Canada: Results From the TransFORmation of IndiGEnous PrimAry HEAlthcare Delivery (FORGE AHEAD) Program
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Romina Pace, Mariam Naqshbandi Hayward, Harsh Zaran, Roland Dyck, Michael E. Green, Onil Bhattacharyya, Merrick Zwarenstein, Joelle Emond, Marie Jebb, Cynthia Benoit, Stewart B. Harris (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

121 - Partnering With the Cree to Develop a Diabetes Prevention Strategy in Families With Prior Gestational Diabetes: In-Depth Interview Results
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Romina Pace, Orenda Loon, Deborah Chan, Dany Gauthier, Josee Nadeau, Helene Porada, Catherine Godin, Jonathan Linton, Paul Linton, Jill Torrie, Kaberi Dasgupta (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

122 - Egg White Hydrolysate Effects in Adipose Tissue of High Fat Diet-Induced Insulin Resistant Rats
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Stepheny C. De Campos Zani, Forough Jahandideh, Jianping Wu, Catherine B. Chan (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

123 - Investigating the Molecular and Metabolic Regulators of Insulin Secretion Over 24 Hours
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Nivedita Seshadri, Youstina Soliman, Anmol Mann, Christine Doucette (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

124 - Withdrawn
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

125 - Altered DNA Methylation and Serum Levels of Metabolites is Associated With Type 2 Diabetes in Adolescents
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Prasoon Agarwal, Brandy A. Wicklow, Allison B. Dart, Elizabeth Sellers, Jonathan M. Mcgavock, Charlotte P.J. Talbot, Meaghan Jones, Mario Fonseca, Wayne Xu, James R. Davie, Animesh Acharjjee, Vernon W. Dolinsky (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

126 - Prevalence of Detectable C-peptide in Longstanding Type 1 Diabetes (T1D)
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Leif Erik Lovblom, Nancy Cardinez, Andrej Orszag, Alanna Weisman, Vera Bril, David Cherney, Bruce A. Perkins (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

127 - Poor Sleep, Increased Stress, and Complications in Youth With Type 2 Diabetes (T2D)
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Melissa Gabbs, Teresa Pinto, Allison B. Dart, Elizabeth Sellers, Jonathan M. Mcgavock, Brandy A. Wicklow (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

128 - Trend and Determinants of Cholesterol-Lowering Medication Use Among Patients With Diabetes Mellitus in Canada: A Repeated Cross-Sectional Study
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Harpreet Kaur Khangura, Wasem Alsabbagh (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

129 - Age at Diagnosis, Glycemic Control and Responses to Oral Blood Glucose Lowering Drugs in Type 2 Diabetes: A Population-Based Study
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Calvin Ke, Therese A. Stukel, Baiju R. Shah, Eric Lau, Ronald C.W. Mawing-Yee So, Alice P. Kong, Elaine Chow, Juliana C.N. Chan, Andrea Luk (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

130 - Diabetes and Homelessness: A Community-Based Participatory Research Project
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): David Campbell, Rachel Campbell, Patricia O’campo, Gillian L. Booth, Kerry Mcbrien, Priya Vasa, Stephen Hwang (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

131 - Identifying Type 1 Diabetes in Electronic Medical Records and Administrative Data in Ontario
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Alanna Weisman, Karen Tu, Jacqueline Young, Matthew Kumar, Peter C. Austin, Liisa Jaakkimainen, Lorraine L. Lipscombe, Ronnie Aronson, Gillian L. Booth (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

132 - Health-Care Visits in Youth With Diabetes of Transitioning Age
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Sonia Butalia, Susan Crawford, DaniÈle Pacaud (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

133 - The Canadian Partnership for Tomorrow Project: Canada’s Longitudinal Population Laboratory
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Philip Awadalla (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

134 - Efficacy and Clinical Considerations of Flash Glucose Monitoring Among Canadian Adults With Diabetes
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Aria Jazdarehee, Jordanna Kapeluto, Monika Pawlowska, Jessica Mackenzie-Feder, Benjamin Schroeder, Adam White (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

135 - Diabetes Overtreatment and Averse Outcomes Among Older Adults With Diabetes: A Population-Based Study
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Iliana C. Lega, Michael Campitelli, Peter C. Austin, Yingbo Na, Susan E. Bronskill, Freda Leung, Afshan Zahedi, Catherine Yu, Paula A. Rochon, Lorraine L. Lipscombe (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

136 - Systematic Content Evaluation of Canadian Diabetes Mobile Apps
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Mary Elizabeth Nguyen, Nafis Hossain, Rohin Tangri, Jay Shah, Fiona Thompson-Hutchison, Payal Agarwal, Ilana J. Halperin (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

2019 Appendix: Duality of Interest Disclosures
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

55 - What is Driving Diabetes and its Complications in BC? Geographical and Socioeconomic Variation Between BC Regional Health Authorities
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Wendy Leong, Mike Pennock, Kim Reimer, Jenny Sutherland, Marshall Dahl (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 19, 2019 Category: Endocrinology Source Type: research

Dyslipidemia Management in Adults With Diabetes
Publication date: Available online 12 July 2019Source: Canadian Journal of DiabetesAuthor(s): Julieta Lazarte, Robert A. HegeleAbstractLipid abnormalities beyond elevated low-density lipoprotein (LDL) cholesterol contribute to increased risk of atherosclerotic cardiovascular disease (ASCVD) in type 2 diabetes. We searched for English language randomized controlled trials of lipid-lowering therapies primarily since 2012 that included patients with diabetes. Diet and lifestyle advice are always a starting point for ASCVD prevention in diabetes. After almost 30 years of widespread clinical use in diabetes, statin treatme...
Source: Canadian Journal of Diabetes - September 12, 2019 Category: Endocrinology Source Type: research

Extracorporeal Shock Wave Therapy for Treating Foot Ulcers in Adults With Type 1 and Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Publication date: Available online 23 May 2019Source: Canadian Journal of DiabetesAuthor(s): Qiangru Huang, Peijing Yan, Huaiyu Xiong, Tiankui Shuai, Jingjing Liu, Lei Zhu, Jiaju Lu, Xiue Shi, Kehu Yang, Jian LiuAbstractExtracorporeal shock wave therapy (ESWT) as a new adjuvant therapy has shown a potential capability to promote diabetic foot ulcer (DFU) healing. The purpose of this study was to assess the efficacy and safety of ESWT on the healing of DFUs. The Cochrane Library, PubMed, Embase, Web of Science, China Biology Medicine and reference lists were searched for studies published up to December 2018. Randomized con...
Source: Canadian Journal of Diabetes - September 11, 2019 Category: Endocrinology Source Type: research

Preventing and Treating Diabetes in Canadian Adults With Intellectual and Developmental Disabilities
Publication date: Available online 7 June 2019Source: Canadian Journal of DiabetesAuthor(s): Brianne Redquest, Suhal Ahmed, Robert Balogh, Yona LunskyAbstractDespite emerging evidence that individuals with intellectual and developmental disabilities (IDD) have a high prevalence of diabetes, Canada does not have a strategy to address diabetes in this population. The aim of this review was to review effective health policies and practices to improve diabetes prevention and management developed by other jurisdictions in response to the high prevalence of diabetes among individuals with IDD. To do so, a narrative literature re...
Source: Canadian Journal of Diabetes - September 6, 2019 Category: Endocrinology Source Type: research

Smoking and Diabetes Control in Adults With Type 1 and Type 2 Diabetes: A Nationwide Study From the 2018 National Program for Prevention and Control of Diabetes of Iran
In this study, we aimed to assess the association of smoking with micro- and macrovascular complications of diabetes and lipid and glycemic indices.MethodsWe used the National Program for Prevention and Control of Diabetes of Iran database of 99,651 adult patients with diabetes across Iran. Multiple logistic regression models were used to examine the association between smoking and diabetes complications including cardiovascular disease, neuropathy, nephropathy and retinopathy. This association was adjusted for age, sex, duration of diabetes, glycated hemoglobin (A1C), hypertension, hyperlipidemia, medication, obesity and ...
Source: Canadian Journal of Diabetes - September 5, 2019 Category: Endocrinology Source Type: research

Predictors of large for gestational age birth weight among pregnant women with type 1 and type 2 diabetes: A retrospective cohort study
Publication date: Available online 4 September 2019Source: Canadian Journal of DiabetesAuthor(s): Lisa D. Alexander, George Tomlinson, Denice S. FeigAbstract:ObjectiveTo compare the effects of risk factors for large for gestational age (LGA) birth weight between women with type 1 (TIDM) and type 2 diabetes (T2DM).MethodsA retrospective cohort study was conducted for women with T1DM (n=152) and T2DM (n=255) attending a Diabetes/Pregnancy Clinic 2009 to 2016. Multiple logistic regression analysis was used to identify variables associated with LGA.ResultsLGA was significantly higher in T1DM (39%) than T2DM (17%) (p
Source: Canadian Journal of Diabetes - September 5, 2019 Category: Endocrinology Source Type: research

Perinatal Outcomes Among Different Asian Groups With Gestational Diabetes Mellitus in Ontario: A Cohort Study
ConclusionSouth Asian women with GDM are at lower risk of having an LGA newborn, even after accounting for maternal risk factors or the use of an ethnicity-specific birthweight curve.RésuméObjectifLe but de la présente étude était de déterminer si les issues périnatales sont différentes entre les sous-groupes de femmes blanches et de femmes asiatiques ayant un diabète sucré gestationnel (DSG) à l'aide des courbes de poids à la naissance normaux ou spécifiques à l'origine ethnique.MéthodesLa présente étude ...
Source: Canadian Journal of Diabetes - September 5, 2019 Category: Endocrinology Source Type: research

An Idiographic Investigation of Diabetic Alert Dogs' Ability to Learn From a Small Sample of Breath Samples From People With Type 1 Diabetes
ConclusionsThe results suggest that some dogs can be trained to detect hypoglycemic breath of an individual with T1D, but detection may not transfer to novel samples from other individuals. Results should be interpreted with caution, as the dogs were trained with only a small number of breath samples before testing.RésuméObjectifLe marché des chiens d'alerte au diabète est en croissance, mais peu de publications ont porté sur la capacité des chiens à détecter de façon fiable l'hypoglycémie. Notre but était de déterminer si 2 chiens pourraie...
Source: Canadian Journal of Diabetes - August 31, 2019 Category: Endocrinology Source Type: research

Demographics of Women With Type 1, Type 2 and Gestational Diabetes Attending a Diabetes and Pregnancy Clinic in 2000–2002, 2010–2012 and 2014–2016
Publication date: Available online 19 July 2019Source: Canadian Journal of DiabetesAuthor(s): Parul Khanna, Lindsey Chow, Evan Brydges, Kingsley Anukum, Selina Liu, Jeffrey L. Mahon, Tisha Joy, Ruth McManusAbstractPregnancies complicated by diabetes are increasingly frequent. The Endocrine and Pregnancy Clinic [EPC] at St Joseph’s Health Care London is the stable, local provider of all outpatient pregnancy diabetes care, thereby providing an opportunity to document patient characteristics with time.MethodsEPC charts were reviewed for: 2000-2002; 2010-2012; 2014-2016 documenting DM type (T1DM, T2DM, GDM); age; weight;...
Source: Canadian Journal of Diabetes - August 27, 2019 Category: Endocrinology Source Type: research

A longitudinal study on the association between diabetic foot disease and health related quality of life in people with type 2 diabetes
ConclusionAlthough participants with diabetic foot disease reported lower HRQOL at baseline, they had similar changes compared to those without diabetic foot disease during the two-year follow-up. Efforts to maintain general health and early intervention to prevent diabetic foot disease may help to avoid initial deterioration of physical health and HRQOL. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 26, 2019 Category: Endocrinology Source Type: research

Diabetic Retinopathy and Vascular Endothelial Growth Factor (VEGF) Gene I/D polymorphism: at Glance
Publication date: Available online 25 August 2019Source: Canadian Journal of DiabetesAuthor(s): Sanam Zeib Khan, Nida Ajmal, Rozeena ShaikhAbstractDiabetic Retinopathy (DR) is microvascular complication of retina of eye and regarded as one of the major source of blindness around the globe. It is complex disorder that is characterized by both genetic & environmental factors. Vascular Endothelial Growth Factor (VEGF) gene is one of the main candidate gene for DR; also it is involved in several diseases such as microvascular complications of DM and cancer. The VEGF gene is extremely polymorphic. The 18bp fragment (I/D) po...
Source: Canadian Journal of Diabetes - August 26, 2019 Category: Endocrinology Source Type: research

Exploring the Experiences of Adults With Type 2 Diabetes on Sodium Glucose Cotransporter 2 Inhibitors
ConclusionsAn improved dietary-related quality of life was described by some participants. Although not all individuals were seen to move into the Realizing phase after initiating an SGLT-2 inhibitor, there appeared to be an opportunity to create a behaviour change after positive Reckoning experiences.RésuméObjectifAucune étude ne s'est déjà penchée sur la qualité de vie liée à l'alimentation des patients atteints de diabète de type 2 qui prennent des inhibiteurs du cotransporteur sodium-glucose de type 2 (SGLT2), la plus récente classe de m&eacut...
Source: Canadian Journal of Diabetes - August 24, 2019 Category: Endocrinology Source Type: research

Screening for Atherosclerotic Cardiovascular Disease in Patients with Diabetes: Controversies and Guidelines
Publication date: Available online 23 August 2019Source: Canadian Journal of DiabetesAuthor(s): Paolo RaggiAbstractIf a disease state is highly prevalent and its consequences are severe, it may be appropriate to seek methods to identify it early in order to forestall its development and complications. Diabetes mellitus is a proven risk factor for the development of atherosclerosis although its face and outcome are changing as shown in contemporary clinical trials. In fact, decompensated heart failure (HF) seems to drive the hospitalization rate in patients with diabetes and the mortality from HF is reduced with modern hypo...
Source: Canadian Journal of Diabetes - August 24, 2019 Category: Endocrinology Source Type: research

Exogenous insulin-induced localized acanthosis nigricans: A rare injection site complication
Publication date: Available online 23 August 2019Source: Canadian Journal of DiabetesAuthor(s): Rimesh Pal, Rajsmita Bhattacharjee, Debajyoti Chatterjee, Sanjay Kumar Bhadada, Anil Bhansali, Pinaki Dutta (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 24, 2019 Category: Endocrinology Source Type: research

Glucagon-Like Peptide-1 Receptor Agonists in Type 2 Diabetes: Review of Cardiovascular Outcome Trials
Publication date: Available online 23 August 2019Source: Canadian Journal of DiabetesAuthor(s): Elodie M. Varin, Brent A. McLean, Julie A. LovshinAbstractPeople with type 2 diabetes (T2D) are at heightened risk for developing cardiovascular (CV) events, and cardiovascular disease (CVD) is the leading cause of premature death amongst adults with T2D. Unfortunately, historically, some anti-diabetes agents were implicated in worsening cardiovascular function, despite improving glycemic and metabolic control. Accordingly, over a decade ago, health regulatory bodies modified approval requirements for novel anti-diabetes pharmac...
Source: Canadian Journal of Diabetes - August 24, 2019 Category: Endocrinology Source Type: research

The Role of Sodium-Glucose co-Transporter -2 Inhibition in the Treatment of Patients with Heart Failure
Publication date: Available online 23 August 2019Source: Canadian Journal of DiabetesAuthor(s): Abhinav Sharma, Justin A. Ezekowitz (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 24, 2019 Category: Endocrinology Source Type: research