Response to the Letter to the Editor From Dr. Spence, “Egg Consumption and Cardiovascular Risk”
Publication date: June 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 3Author(s): Caroline Richard, Catherine J. Field, Rene L. Jacobs, Maria Ricupero (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Benefits May Have Been Exaggerated: Comments on “Natural Health Products and Diabetes: A Practical Review”
Publication date: June 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 3Author(s): Peter Senior (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Response to the Letter to the Editor From Dr. Senior, “Benefits May Have Been Exaggerated: Comments on ‘Natural Health Products and Diabetes: A Practical Review’”
Publication date: June 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 3Author(s): Candace Necyk (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Should the Clinical Criteria for Suspecting Glucokinase Mutation-Related Hyperglycemia (MODY-2) Be Revisited During Pregnancy?
Publication date: June 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 3Author(s): Carl-Hugo Lachance, Michel Baillargeon (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Emergency Department Management of Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State in Adults: National Survey of Attitudes and Practice
ConclusionsAlthough Canadian emergency physicians were generally supportive of the guidelines, many were unaware that these guidelines existed, and barriers to their implementation were reported. These results suggest the need to improve knowledge translation strategies across Canadian emergency departments to standardize management of diabetic ketoacidosis and hyperosmolar hyperglycemic states and support the highest quality of patient care, as well as to ensure that future guidelines include management strategies applicable to the emergency department setting.RésuméObjectifsEn 2013, l'Association canadienne...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

GTF-231, a Mixture of Gymnemic Acid, Trigonelline and Ferulic Acid Significantly Ameliorates Oxidative Stress in Experimental Type 2 Diabetes in Rats
ConclusionsThe observed antioxidant potential of GTF-231 may account for its significant antidiabetic properties.RésuméObjectifsD'après un rapport de la US National Health and Nutrition Examination Survey, près de 60 % des patients diabétiques présentent plus de 1 complication associée au diabète à long terme. Le diabète de type 2 est une perturbation multifactorielle du métabolisme qui représente plus de 95 % des personnes diabétiques et qui exige généralement des interventions thérapeutiques à cibles mul...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Glycated Hemoglobin, Albuminuria and Surrogate Markers of Macrovascular Disease in Adults Without Diabetes: The Guangzhou Biobank Cohort Study, Cardiovascular Disease Subcohort
ConclusionsAlthough there was evidence suggesting differential associations, the performance of the glycemic indices was similar, and their association with macrovascular disease and albuminuria was modest.RésuméObjectifsComparer l'utilité clinique des concentrations de l'hémoglobine glyquée (A1c) comme marqueur précoce de l'albuminurie, de la maladie macrovasculaire et de la maladie cardiovasculaire infraclinique aux concentrations de la glycémie à jeun et de la glycémie postprandiale au sein d'une population chinoise bien définie sans antéc&eacu...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Association of Vitamin D Receptor Gene Polymorphism in Adults With Type 2 Diabetes in the Kashmir Valley
ConclusionsVDR gene polymorphisms appear to be an important genetic determinant in the progression of diabetes. Considering the important predisposition risk factor, we observed that Taq-1 and Bsm-1 were strongly associated with diabetes in northern Indians. But requires further study as a probable genetic risk marker for diabetes.RésuméObjectifsEnviron 1 milliard de personnes de divers groupes ethniques et groupes d'âge ont une carence en vitamine D. La forte prévalence de cette carence constitue un problème de santé publique d'une importance cruciale puisque l'hypovitaminose D est...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Developing and Implementing a Food Insecurity Screening Initiative for Adult Patients Living With Type 2 Diabetes
ConclusionsUsing a standardized, respectful method of assessing food insecurity can better equip health-care providers to support food-insecure patients with diabetes self-management. Further evaluation of this initiative is needed to determine how food insecurity screening can affect patients' self-management and related health outcomes.RésuméObjectifsLe dépistage systématique de l'insécurité alimentaire est recommandé lors des soins aux diabétiques afin d'élaborer des interventions plus personnalisées qui soutiendront davantage la prise en charge auton...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Potential Predictive Role of Lipid Peroxidation Markers for Type 2 Diabetes in the Adult Tunisian Population
Publication date: June 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 3Author(s): Houda Bouhajja, Faten Hadj Kacem, Rania Abdelhedi, Marwa Ncir, Jordan D. Dimitrov, Rim Marrakchi, Kamel Jamoussi, Ahmed Rebai, Abdelfattah El Feki, Mohamed Abid, Hammadi Ayadi, Srini V. Kaveri, Mouna Mnif-Feki, Noura Bougacha-ElleuchAbstractObjectivesWe evaluated the potential clinical relevance of malondialdehyde (MDA) and autoantibodies to copper oxidized low-density lipoprotein (CuOx-LDL) in type 2 diabetes occurrence.MethodsThis cross-sectional study enrolled 69 normoglycemic subjects, 18 prediabetic patients and 108 type 2 di...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

A Genotype-First Approach for Clinical and Genetic Evaluation of Wolcott-Rallison Syndrome in a Large Cohort of Iranian Children With Neonatal Diabetes
ConclusionWRS is a common cause of PNDM in children of consanguineous parents. Furthermore, clinical diagnosis of WRS would have been delayed or possibly missed without genetic testing because this study shows that the associated features of WRS might be obscured by a diagnosis of PNDM. Therefore EIF2AK3 should be considered for any infant and young child with PNDM, particularly if the parents are related.RésuméObjectifLe syndrome de Wolcott-Rallison (SWR), une maladie autosomique récessive extrêmement rare, est caractérisé par un diabète sucré néonatal permanen...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Children With Type 1 Diabetes Have Delayed Flow-Mediated Dilation
ConclusionsDelayed FMD patterns occur in children with type 1 diabetes and detect children who have more severe vascular abnormalities. The standard FMD60s remains the better marker to identify children at increased risk for cardiovascular disease.RésuméObjectifsLes enfants atteints du diabète de type 1 montrent une accélération de l'athérosclérose associée à un dysfonctionnement endothélial précoce déterminé par la diminution de la dilatation induite par le flux (DIF) 60 secondes après un stress ischémique (DIF pr&eacu...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Exploring Canadian Physicians' Experiences With Type 2 Diabetes Care for Adult Indigenous Patients
ConclusionsAdaptations in diabetes care by physicians grounded in the historical, social and cultural contexts of their Indigenous patients offer opportunities for improving care quality, but policy and health system supports and structural competency are needed.RésuméObjectifsLe point de vue des médecins qui soignent les patients autochtones diabétiques offre de nombreuses pistes sur la prestation des services de santé. L'objectif de la présente étude était de présenter le point de vue des médecins du Canada sur les soins aux patients autochtones diab&e...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Cognitive Impairment Mediates Workplace Impairment in Adults With Type 2 Diabetes Mellitus: Results From the Motivaction Study
ConclusionsAmong employed Canadians, impaired glucose tolerance is highly associated with impaired workplace performance. We report a novel finding insofar as the association between depressive symptoms and workplace impairment in individuals with impaired glucose regulation is mediated principally by self-rated cognitive dysfunction.RésuméObjectifsLe diabète sucré de type 2 (DS) est associé à une diminution importante des capacités reliées au travail. Toutefois, les rôles médiateurs de la performance au travail lors de DS ne sont pas bien définis....
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Hyperglycemia in Young Adults With Types 1 and 2 Diabetes Seen in the Emergency Department: A Health Records Review
This study's objective was to describe emergency department (ED) utilization because of hyperglycemia in emerging adults with diabetes and to characterize 30-day outcomes, including return visits and admission for hyperglycemia.This was a health-records review of emerging adults presenting over a 1-year period to 4 tertiary care EDs; the patients had known histories of diabetes and final diagnoses of hyperglycemia, diabetic ketoacidosis or hyperosmolar hyperglycemia. Research personnel collected data concerning patients' characteristics, treatments and dispositions and determined whether the patients returned to the ED bec...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Semaglutide: Review and Place in Therapy for Adults with Type 2 Diabetes
This article overviews data from across the semaglutide clinical trial program, including efficacy and safety results, and findings from post hoc analyses. The potential place of semaglutide in clinical practice is discussed. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

In-Vivo Anti-Diabetic and Wound Healing Effect of Antioxidant Gold Nanoparticles Synthesized Using Insulin Plant (Chamaecostus Cuspidatus)
ConclusionInterestingly the functionalization of gold nanoparticles as antidiabetic nanomaterials is achieved and the gold nanoparticles based drugs will be more active to interact with the targets if subjected to further studies. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

End of Life – What does that mean for management of adult patients with type 1 diabetes?
Publication date: Available online 20 June 2018Source: Canadian Journal of DiabetesAuthor(s): Jill Trinacty, Erin Keely (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

High Proportion of Type 2 Diabetes Adults with Poor Glycated Hemoglobin Perceived that Their Diabetes Control was “Excellent”
ConclusionThis study demonstrates discordance between perception of diabetes control and HbA1C which may hinder effective diabetes care. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Frailty, Health Related Quality of Life, Cognition, Depression, Vitamin D and Health Care Utilization in an Ambulatory Adult Population with Type 1 and Type 2 Diabetes Mellitus and Chronic Kidney Disease: a cross sectional analysis.
Publication date: Available online 20 June 2018Source: Canadian Journal of DiabetesAuthor(s): Adame Perez SI, Senior PA, Field CJ, Jindal K, Mager DRAbstractBackgroundFrailty can cause an increased vulnerability to adverse health outcomes such as falls, fractures, depression and reduced health related quality of life (HRQoL). This cross sectional study compared differences in body composition, HRQoL, mental health, cognitive and vitamin D (VitD) status and health care utilization between frail and non-frail adults with Diabetes Mellitus (DM Type 1 and Type 2) with chronic kidney disease (CKD stages 1-5).Methods and Partici...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

The health and healthcare of adults with type 1 and 2 diabetes across the estimated glomerular filtration rate spectrum
Publication date: Available online 21 June 2018Source: Canadian Journal of DiabetesAuthor(s): Kristin K Clemens, Alexandra Ouédraogo, Danielle M Nash, Amit X Garg, Salimah Z ShariffAbstractBackgroundLittle is known about the health and healthcare patterns of patients with diabetes by their estimated glomerular filtration rate, especially within a publicly-funded healthcare system.MethodsUsing linked healthcare databases in Ontario, Canada, we performed a population-based study of adults aged 50 and older (mean age 68 years) with prevalent diabetes on January 1, 2014. We categorized patients according to their level ...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Storytelling to Support disease self-management among Adults with type 2 diabetes
ConclusionInformal group storytelling enables patients to discuss, understand, and give personal meaning to the information that was exchanged; and facilitates clinical educators to better understand patients’ concerns, gaps in knowledge, and how-to’ strategies that can inform their practice. The group-storytelling intervention is acceptable to patients and facilitators and can be delivered with high fidelity. Further research into effective recruitment methods and evaluation of the intervention's impact on diabetes self-management is required. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Muscarinic agonist ameliorates insulin secretion in Wfs1 deficient mouse
ConclusionsActivation of muscarinic pathway to potentiate insulin secretion may present a target to manage diabetes resulting from Wfs1 deficiency. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Sleep Duration and Obesity in Children and Adolescents: Review
Publication date: Available online 4 July 2018Source: Canadian Journal of DiabetesAuthor(s): Shannon WagnerAbstractIncreased rates of obesity internationally have drawn significant attention. In particular, researchers and practitioners are seeking new information about risk factors for obesity that could potentially be areas for preventative interventions. Given that obesity rates in children and adolescents are increasing worldwide, particular attention to child and adolescent obesity is needed. A large, and growing, body of research indicates that inadequate sleep duration is linked to obesity. The current article revie...
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Frailty status and gait parameters of older women with type 2 diabetes
Publication date: Available online 4 July 2018Source: Canadian Journal of DiabetesAuthor(s): Renata Noce Kirkwood, Izabela Lara Borém, Rosana Ferreira Sampaio, Vivianne Kellen Gonçalves Ferreira, Jennifer Cristina de Almeida, Sâmara Bragança Bastos Guimarães, Bruno de Souza Moreira (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 10, 2018 Category: Endocrinology Source Type: research

Knowledge Translation to Optimize Adult Inpatient Glycemic Management with Basal Bolus Insulin Therapy and Improve Patient Outcomes
This study was conducted in 2 phases and focused on the hospitalist provider group across 4 acute care facilities in Calgary. Phase 1 involved a qualitative evaluation of provider and site specific barriers and facilitators, which were mapped to validated interventions using behaviour change theory. This informed the co-development and optimization of the BBIT Knowledge Translation toolkit, with each tool targeting a specific barrier to improved diabetes care practice, including BBIT ordering. In Phase 2, the BBIT Knowledge Translation toolkit was implemented and evaluated, focusing on BBIT ordering frequency, as well as s...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

The Effect of Omega-3 on Circulating Adiponectin in Adults with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
The objective of this study was to evaluate the effect of omega-3 (food or supplement) on circulating adiponectin in patients with type 2 diabetes through a systematic review of meta-analyses of randomized controlled trials.PubMed, Scopus and Web of Science were searched for relevant studies through May 2016. Two researchers screened and abstracted the literature independently. Pooled estimates were obtained using the random-effects models.Overall, omega-3 increased adiponectin by 0.57 µg/mL (95% confidence interval [CI] 0.15 to 1.31; p=0.01, I-square=74.2% p for heterogeneity
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

The Association Between Taste Impairment and Serum Zinc Concentration in Adult Patients with Type 2 Diabetes
In this study, we aimed to elucidate the association between taste acuity and serum zinc concentration in patients with type 2 diabetes.MethodsWe enrolled 29 patients who were hospitalized and asked them to attend a 2-week diabetes education program. Fasting blood samples were obtained on the morning of the first day and 2 weeks after hospitalization. The acuity of sweet, salty, sour or bitter taste was evaluated by a filter-paper disc method. Correlations among taste acuity, glycemic control and serum zinc concentration were analyzed using the Spearman rank correlation coefficient.ResultsThe following parameters (mean &pl...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Accumulation of Advanced Glycation Endproducts and Subclinical Inflammation in Deep Tissues of Adult Patients With and Without Diabetes
ConclusionsAGE contents were strongly correlated with each other and were accompanied by inflammatory cells. Skin AF measurement could provide information about the systemic accumulation of AGEs.RésuméObjectifsLes produits terminaux de la glycation avancée (PTGA) jouent un rôle essentiel dans le développement des complications du pied chez les personnes diabétiques. L'autofluorescence (AF) cutanée déterminerait de manière non effractive l'accumulation tissulaire des PTGA. La présente étude a permis d'évaluer l'association entre l'AF cutan&ea...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Activated Mast Cells Mediate Low-Grade Inflammation in Type 2 Diabetes: Interleukin-37 Could be Beneficial
Publication date: Available online 31 January 2018Source: Canadian Journal of DiabetesAuthor(s): Pio Conti, Gianpaolo Ronconi, Spyridon K. Kritas, Alessandro Caraffa, Theoharis C. TheoharidesAbstractMast cells (MCs) promote guest immune responses to parasites and play a critical role in allergic and inflammatory reactions. Once they have been activated, MCs release highly inflammatory compounds that can provoke serious pathologic signs that can lead to death. MCs generate a number of preformed, de novo synthesized compounds and inflammatory cytokine/chemokine synthesis in response to the high-affinity (Kd=10–10 M) im...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Diabetes Risk in Childhood Cancer Survivors: A Population-Based Study
ConclusionsOur study supports evidence of an increased risk for diabetes in survivors of childhood cancer. Future research is warranted for better identification of treatment-related risk factors for diabetes in this population.RésuméObjectifsGrâce à l'amélioration constante de la survie après un cancer chez l'enfant, les conséquences à long terme des traitements contre le cancer sur la santé retiennent de plus en plus l'attention. Le diabète apparaît comme une conséquence tardive potentielle de la thérapie contre le cancer. Toutefois,...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Direct Health-Care Costs and Productivity Costs Associated With Hypoglycemia in Adults With Type 1 and Type 2 Diabetes Mellitus That Participated in the Canadian Hypoglycemia Assessment Tool Program
ConclusionsThe impact of hypoglycemia events on health-care resource utilization and work productivity leads to substantial direct and indirect costs in Canadian patients with diabetes.RésuméObjectifsIl existe peu de données sur le coût des épisodes d'hypoglycémie chez les Canadiens atteints du diabète de type 1 ou de type 2. L'objectif de la présente étude était d'estimer les coûts directs et indirects des soins de santé associés à l'hypoglycémie en s'appuyant sur une cohorte de 498 patients canadiens de l'étude m...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

What Can We Learn From Diabetes-Related YouTube Videos?
Publication date: Available online 31 January 2018Source: Canadian Journal of DiabetesAuthor(s): Benjamin K.P. Woo (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Evaluation of a Diabetes Coach Program Aimed to Improve the Care of Children and Youth With Type 1 Diabetes and With Compromised Control
ConclusionsParticipation in the DCP decreased A1C values in pediatric patients; however, the levels were not sustained after visits stopped. Pediatric health coaches may play an important role in the management of type 1 diabetes, but further research is needed to explore their benefits and how positive effects can be sustained.RésuméObjectifsÉvaluer les répercussions du Diabetes Coach Program (DCP) sur les concentrations de l'hémoglobine glyquée (A1c) chez les jeunes atteints du diabète de type 1. Les jeunes ont été orientés vers le DCP et y ont partici...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Qualitative Evaluation of the Barriers and Facilitators Influencing the Use of an Electronic Basal Bolus Insulin Therapy Protocol to Improve the Care of Adult Inpatients With Diabetes
ConclusionsThe outcomes highlight the complex interplay between educational, organizational and technical themes and the significance of employing a systemic approach to support the implementation of electronic inpatient glycemic-management protocols within complex social organizations.RésuméObjectifsUne évaluation qualitative des répercussions perçues d'un nouveau modèle d'ordonnances électroniques relatif aux schémas insuliniques de type basal-bolus qui est fondé sur des données probantes sur le flux de travail et la pratique cliniques, et une explorat...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Dipeptidyl Peptidase-4 Inhibitor, Vildagliptin, Improves Trabecular Bone Mineral Density and Microstructure in Obese, Insulin-Resistant, Pre-diabetic Rats
ConclusionsVildagliptin had a beneficial effect on the bone of obese insulin-resistant rats with prediabetes, particularly at the trabecular site. Such benefit probably results from enhanced bone formation rather than from suppressed bone resorption.RésuméObjectifL'insulinorésistance associée à l'obésité et le diabète de type 2 détériorent énormément les propriétés mécaniques et la qualité de l'os. Toutefois, puisque plusieurs médicaments contre le diabète, particulièrement les thiazolidinedi...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Understanding the Experiences of East African Immigrant Women with Gestational Diabetes Mellitus
ConclusionsStudy findings point to the need for more context-specific and culturally appropriate support and care. Diagnoses of GDM extended beyond the individuals affected and impacted their families culturally, psychologically and financially. Addressing the emergent themes during pregnancy is imperative to improving care providers' engagement with EA immigrant women in postpartum diabetes screening activities and beyond. The findings of this study contain elements transferable to other immigrant groups in similar socioecologic contexts.RésuméObjectifsLes femmes de l'Afrique orientale (AO) représente...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Serum Brain-Derived Neurotrophic Factor is Related to Platelet Reactivity and Metformin Treatment in Adult Patients With Type 2 Diabetes Mellitus
ConclusionsOur results suggest that BDNF may be associated with lipid metabolism and that increased production of BDNF may be related to metformin treatment. Moreover, we showed an association between BDNF levels and platelet reactivity; we found that serum BDNF levels in patients with type 2 diabetes who had high platelet reactivity were higher than in subjects with normal platelet reactivity despite antiplatelet therapy.RésuméObjectifsL'objectif de la présente étude était d'examiner l'association des concentrations sériques du facteur neurotrophique dérivé du cervea...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Changing the Conversation: Diabetes Management in Adults with Severe Mental Illnesses and Type 2 Diabetes
ConclusionsThis work offers an alternative conceptualization of diabetes management that moves beyond idealized concepts of self-care to introduce the social realities of patients as they attempt to enact and negotiate medical directives. This understanding encourages a shift toward social and contextual understandings of the lived realities of patients. Attention to how social context informs patients' realities may assist in the development of new patient-oriented grounds for public health strategies and clinical practices and may challenge traditional understandings of compliance and noncompliance.RésuméOb...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Targeted Glycemic Control for Adult Patients with Type 2 Diabetes Mellitus in the Acute Care Setting
Publication date: Available online 8 February 2018Source: Canadian Journal of DiabetesAuthor(s): Ali Pourmand, Maryann Mazer-Amirshahi, Amy Caggiula, Aria Nawab, Christopher Payette, Samuel JohnsonAbstractDiabetes mellitus and complications arising from the disease are a leading cause of morbidity and mortality worldwide. With increasing prevalence over the past 50 years and an estimated 20% of health-care spending dedicated to the disease, diabetes is considered by many to be a true public health emergency. Several protocols and management options exist to maximize glycemic control in the ambulatory setting, but the optim...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Liver Enzymes, Fatty Liver and Type 2 Diabetes Mellitus in a Jinchang Cohort: A Prospective Study in Adults
ConclusionsOur results suggest that the incidence of T2DM in the group with fatty liver is significantly higher than that in the normal population, and the rise of serum AST, GGT and ALT levels are risk factors independent of fatty liver for the development of T2DM after adjusting for confounding factors.RésuméObjectifsOn ignore encore si les enzymes hépatiques ou l’interaction des diverses enzymes hépatiques constituent un prédicteur du diabète sucré de type 2 (DST2), qui est indépendant de la stéatose hépatique.MéthodesUn total de 48&thi...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

We Can Work (It) Out Together: Type 1 Diabetes Boot Camp for Adult Patients and Providers Improves Exercise Self-Efficacy
ConclusionsThese findings suggest that a 4-week education- and exercise-focused program improves DCPs' self-efficacy in providing exercise advice to patients. People with type 1 diabetes did not experience an improvement in exercise self-efficacy; however, the study supports the use of continuous glucose monitoring and the grouping of DCPs and individuals with type 1 diabetes to facilitate experiential learning.RésuméObjectifsCe projet avait pour objectif le recours aux séances d'enseignement et d'exercice pour rehausser le sentiment d'efficacité personnelle dans la pratique de l'exercice chez l...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Patients' with Type 1 and 2 Diabetes Perceptions Towards Current and Advanced Technologies of Blood Glucose Monitoring: a Prospective Study
This study showed that 24.2% (n=50/207) of the participants were asked to monitor their blood glucose between 3-4 times per day when diagnosed, however only 14.0% (n=29/207) were compliant when the study commenced. A further decline in adherence, from diagnosis to study initiation, was seen in participants who had been asked to monitor their blood glucose levels at least five times per day. When questioned about their reasons for poor adherence, 59.2% (n= 123/207) of the cohort indicated that this is due to the painful, uncomfortable and inconvenience nature of testing. In addition, 75.8% (n=157/207) of the participants ex...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

The Association of Potato Intake with Risk for Incident Type 2 Diabetes in Adults
ConclusionsOur findings indicate that, in Tehranian adults, a moderate intake of dietary total and boiled, but not fried, potatoes may be associated with a lower risk for incident diabetes.RésuméObjectifsDes études antérieures indiquent que le risque de diabète associé à une consommation élevée de pomme de terre diffère selon les populations. Nous avons cherché à étudier les associations entre l'ingestion de pommes de terre sous forme bouillie, frite ou totale et le risque d'incidence de diabète chez les adultes téh&eac...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Endorsement of Diabetes Canada's Alternative Approach for Gestational Diabetes Diagnosis
Publication date: Available online 27 February 2018Source: Canadian Journal of DiabetesAuthor(s): Jason M. Kong (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Serum Vitamin D and Its Upregulated Protein, Thioredoxin Interacting Protein, are Associated with Beta-Cell Dysfunction in Adult Patients with Type 1 and Type 2 Diabetes
ConclusionsOur data showed that vitD and TXNIP were associated with different beta-cell dysfunction markers, indicating their potential abilities to predict the beta-cell status in people with diabetes.RésuméObjectifsLe diabète sucré est caractérisé soit par un défaut total de sécrétion d'insuline, comme dans le diabète de type 1, soit par une dégradation des cellules bêta pancréatiques dans le diabète de type 2. La vitamine D (vitD) et la protéine d'interaction avec la thiorédoxine (TXNIP) ont été m...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Results From a Feasibility Study of Square-Stepping Exercise in Older Adults with Type 2 Diabetes and Self-Reported Cognitive Complaints to Improve Global Cognitive Functioning
ConclusionsSSE should be evaluated further to improve its feasibility in older adults with type 2 diabetes. This study provides preliminary evidence that SSE improves executive function in adults with type 2 diabetes and self-reported cognitive complaints.RésuméObjectifsLes adultes atteints de diabète sucré de type 2 sont à risque accru de démence. Par conséquent, nous avons proposé une initiative appelée programme d'exercice par étapes (SSE) dans le but d'atténuer ce risque. Notre objectif principal était d'évaluer la faisabilit&eac...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Fear of Falling and Balance Confidence in Older Adults With Type 2 Diabetes Mellitus: A Scoping Review
Publication date: Available online 6 March 2018Source: Canadian Journal of DiabetesAuthor(s): Patricia Hewston, Nandini DeshpandeAbstractType 2 diabetes mellitus is highly prevalent in older adults (≥65 years of age) and increases fall risk. Fear of falling and low balance confidence are reported in both fallers and nonfallers and can potentially be more debilitating than a fall itself. Therefore, the objective of this scoping review was to examine and map the current research evidence of balance confidence and fear of falling in older adults with type 2 diabetes. A search of CINAHL, EMBASE and PubMed was conducted. The...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Optimal HbA1c Cut-Off Point for Diagnosis of Type 2 Diabetes in Iranian Adults
Publication date: Available online 12 March 2018Source: Canadian Journal of DiabetesAuthor(s): Farideh Razi, Patricia Khashayar, Robabeh Ghodssi-Ghassemabadi, Mohsen Mehrabzadeh, Maryam Peymani, Fatemeh Bandarian, Ensieh Nasli EsfahaniAbstractObjectiveThe aim of this study was to evaluate the capability of HbA1c as a tool for identifying diabetic and prediabetic Iranian adults.MethodIn a cross-sectional population-based study, 1813 adults comprised of men and women aged 35-75 years without history of diabetes and hemoglobinopathies were included. Fasting blood glucose and HbA1c levels were obtained. According to ADA criter...
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research

Copeptin and Estimated Insulin Sensitivity in Adults with and Without Type 1 Diabetes: CACTI Study
ConclusionCopeptin does not correlate with markers of IR in T1DM, but strongly correlates in non-T1DM. Thus, elevated vasopressin activity and IR appear to be independent risk factors for vascular complications in T1DM. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 5, 2018 Category: Endocrinology Source Type: research