Diabetes Care Program of Nova Scotia: Celebrating 25 Years of Improving Diabetes Care in Nova Scotia
This article describes the model and highlights its key achievements. With balanced representation from frontline providers through to senior decision makers in health care, the DCPNS works across the age continuum, supporting the implementation of national clinical practice guidelines and, when necessary, developing provincial guidelines to meet local needs. The development and implementation of standardized documentation and data collection tools in all diabetes centres created a robust opportunity for the development and expansion of the DCPNS registry. This registry provides useful clinical and statistical information ...
Source: Canadian Journal of Diabetes - August 17, 2017 Category: Endocrinology Source Type: research

Managing the Course of Diabetic Kidney Disease: From the Old to the New
Publication date: Available online 16 August 2017 Source:Canadian Journal of Diabetes Author(s): Ronald M. Goldenberg, Murray Berall, Christopher T.M. Chan, David Z.I. Cherney, Julie A. Lovshin, Philip A. McFarlane, Peter A. Senior, Subodh Verma, Jordan J. Weinstein Diabetic kidney disease (DKD) is a group of chronic kidney diseases that is associated with significant cardiovascular as well as all-cause morbidity and mortality. Although DKD is often progressive in nature, its evolution can be modified by intensive management of glycemia and blood pressure and inhibition of the renin-angiotensin-aldosterone system. This re...
Source: Canadian Journal of Diabetes - August 17, 2017 Category: Endocrinology Source Type: research

Regarding Insulin Initiation in Type 2 Diabetes Mellitus and the Risk for Hypoglycemia
Publication date: Available online 10 August 2017 Source:Canadian Journal of Diabetes Author(s): Jan Brož, Brian M. Frier (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 10, 2017 Category: Endocrinology Source Type: research

TITRATION: A Randomized Study to Assess 2 Treatment Algorithms with New Insulin Glargine 300 units/mL
Conclusions A patient-driven titration algorithm of 1 unit/day with GLA-300 is effective and comparable to the previously tested EDITION algorithm and is preferred by health-care professionals. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 10, 2017 Category: Endocrinology Source Type: research

Egg Consumption and Cardiovascular Risk
Publication date: Available online 10 August 2017 Source:Canadian Journal of Diabetes Author(s): J. David Spence (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 10, 2017 Category: Endocrinology Source Type: research

Developing and Implementing a Food Insecurity Screening Initiative for Patients Living with Diabetes
Conclusions Using a standardized, respectful method of assessing food insecurity can better equip health-care providers to support food-insecure patients with diabetes self-management. Further evaluation of this initiative is needed to determine how food insecurity screening can affect patients' self-management and related health outcomes. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 8, 2017 Category: Endocrinology Source Type: research

Insights Into the Recognition and Management of SGLT2-Inhibitor-Associated Ketoacidosis: It's Not Just Euglycemic Diabetic Ketoacidosis
Publication date: Available online 7 August 2017 Source:Canadian Journal of Diabetes Author(s): Stephanie Dizon, Erin J. Keely, Janine Malcolm, Amel Arnaout (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 8, 2017 Category: Endocrinology Source Type: research

Is Type 2 Diabetes Associated with Impaired Capacity for Weight Loss?
Publication date: Available online 8 August 2017 Source:Canadian Journal of Diabetes Author(s): Ghadi Antoun, Majid Nikpay, Ruth McPherson, Mary-Ellen Harper, Robert Dent (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 8, 2017 Category: Endocrinology Source Type: research

Framing Obesity as a Health Issue: Differences in Public and Professional Perceptions between Canada and the United States
Publication date: Available online 28 July 2017 Source:Canadian Journal of Diabetes Author(s): Bonnie L. Kuehl, Sara F.L. Kirk, Nathalie Dumas, Theodore K. Kyle (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 28, 2017 Category: Endocrinology Source Type: research

Children with Type 1 Diabetes Have Delayed Flow-Mediated Dilation
Conclusions Delayed FMD patterns occur in children with type 1 diabetes and detect children who have more severe vascular abnormalities. The standard FMD60s remains the better marker to identify children at increased risk for cardiovascular disease. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 25, 2017 Category: Endocrinology Source Type: research

Association of Vitamin D Receptor Gene Polymorphism in Patients with Type 2 Diabetes in the Kashmir Valley
Conclusions VDR gene polymorphisms appear to be an important genetic determinant in the progression of diabetes. Considering the important predisposition risk factor, we observed that Taq-1 and Bsm-1 were strongly associated with diabetes in northern Indians. But requires further study as a probable genetic risk marker for diabetes. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 22, 2017 Category: Endocrinology Source Type: research

Effects of Bariatric Surgery on Energy Homeostasis
Publication date: August 2017 Source:Canadian Journal of Diabetes, Volume 41, Issue 4 Author(s): Wei Li, Denis Richard Bariatric surgery represents the most efficient therapy for severe obesity. It reduces the size of fat stores or the amount of body fat gain. The bariatric surgery procedures currently used include Roux-en-Y gastric bypass and sleeve gastrectomy, which are the most commonly performed procedures. Other procedures are laparoscopic adjustable gastric banding and biliopancreatic diversion. The latter represents the most effective surgery for treatment of severe obesity as well as type 2 diabetes. Bariatric su...
Source: Canadian Journal of Diabetes - July 21, 2017 Category: Endocrinology Source Type: research

Surgery for Diabetes: Clinical and Mechanistic Aspects
Publication date: August 2017 Source:Canadian Journal of Diabetes, Volume 41, Issue 4 Author(s): Jordanna Kapeluto, André Tchernof, Laurent Biertho According to the most recent publication by the Canadian Public Health Agency, obesity affects 25% of adults. In addition, there is a clear association between the recent rise in obesity and the increased prevalence of type 2 diabetes. Medical therapy for obesity has shown limited long-term effectiveness, and surgical treatment is now recognized by medical authorities as part of the armamentarium for the management of type 2 diabetes in severely obese patients. The curr...
Source: Canadian Journal of Diabetes - July 21, 2017 Category: Endocrinology Source Type: research

A Canadian and Historical Perspective on Bariatric Surgery
Publication date: August 2017 Source:Canadian Journal of Diabetes, Volume 41, Issue 4 Author(s): Laurent Biertho, Simon Marceau, Simon Biron (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 21, 2017 Category: Endocrinology Source Type: research

The Rapidly Evolving Landscape of Bariatric Surgery
Publication date: August 2017 Source:Canadian Journal of Diabetes, Volume 41, Issue 4 Author(s): Andre Tchernof, S. John Weisnagel (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 21, 2017 Category: Endocrinology Source Type: research

Emergency Department Management of Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State: National Survey of Attitudes and Practice
Conclusions Although Canadian emergency physicians were generally supportive of the guidelines, many were unaware that these guidelines existed, and barriers to their implementation were reported. These results suggest the need to improve knowledge translation strategies across Canadian emergency departments to standardize management of diabetic ketoacidosis and hyperosmolar hyperglycemic states and support the highest quality of patient care, as well as to ensure that future guidelines include management strategies applicable to the emergency department setting. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 20, 2017 Category: Endocrinology Source Type: research

Potential Predictive Role of Lipid Peroxidation Markers for Type 2 Diabetes in the Tunisian Population
Conclusions Plasma MDA and IgA to CuOx-LDL were significantly associated with blood markers of glucose metabolism. High levels of MDA and IgA to CuOx-LDL could independently predict type 2 diabetes development in normoglycemia and prediabetic subjects. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 20, 2017 Category: Endocrinology Source Type: research

GTF-231, a Mixture of Gymnemic Acid, Trigonelline and Ferulic Acid Significantly Ameliorates Oxidative Stress in Experimental Type 2 Diabetes in Rats
Conclusions The observed antioxidant potential of GTF-231 may account for its significant antidiabetic properties. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 18, 2017 Category: Endocrinology Source Type: research

Response to the Letter to the Editor From Dr. Kawada, “Depressive Symptoms, Diabetes Distress and Serum Hemoglobin A1c in South Asians with Type 2 Diabetes Mellitus Living in Canada”
Publication date: Available online 6 July 2017 Source:Canadian Journal of Diabetes Author(s): Rawel Sidhu, Tricia S. Tang (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 7, 2017 Category: Endocrinology Source Type: research

Glycated Hemoglobin, Albuminuria and Surrogate Markers of Macrovascular Disease: The Guangzhou Biobank Cohort Study, Cardiovascular Disease Subcohort
Conclusions Although there was evidence suggesting differential associations, the performance of the glycemic indices was similar, and their association with macrovascular disease and albuminuria was modest. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 6, 2017 Category: Endocrinology Source Type: research

Predictors of Serum Adiponectin in Patients with Prediabetes and Type 2 Diabetes
Publication date: Available online 3 July 2017 Source:Canadian Journal of Diabetes Author(s): Tomoyuki Kawada (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 4, 2017 Category: Endocrinology Source Type: research

Anti-Inflammatory, Anti-Apoptotic and Pro-Proliferative Effects of Vitis Vinifera Seed Ethanolic Extract in the Liver of Streptozotocin-Nicotinamide-Induced Diabetes in Male Rats
Conclusions The anti-inflammatory, anti-apoptotic and pro-proliferative effects of VVSEE could account for its hepatoprotective actions in diabetes. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 1, 2017 Category: Endocrinology Source Type: research

Low Hepcidin in Diabetes Mellitus: Examining the Molecular Links and Their Clinical Implications
Publication date: Available online 26 June 2017 Source:Canadian Journal of Diabetes Author(s): Driton Vela, Ramadan B. Sopi, Mitko Mladenov The relationship between iron and glucose metabolism has been evidenced strongly, but the molecular mediation of this connection is just being revealed. The discovery of hepcidin as the prime controller of iron metabolism has paved the way for understanding the main actors behind this mediation. Recent data suggest that insulin therapy and probably other diabetes drugs can influence hepcidin production, thus influencing the iron load in cells. Correcting iron load through hepcidin exp...
Source: Canadian Journal of Diabetes - June 27, 2017 Category: Endocrinology Source Type: research

Adherence to Guidelines for Inpatient Pharmacologic Management of Type 2 Diabetes and Glycemic Outcomes
Conclusions Adherence to guidelines for inpatient type 2 diabetes management is good and may be greater with more training. Hyperglycemia was more common in patients who did not receive guideline-based care. Hypoglycemia was uncommon and did not appear to be more common in the guideline-adherent group, although numbers were small. These results may alleviate physicians' fear that providing adequate insulin to hospitalized patients may cause hypoglycemia. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - June 27, 2017 Category: Endocrinology Source Type: research

Adherence to Diabetes Dietary Guidelines Assessed Using a Validated Questionnaire Predicts Glucose Control in Individuals with Type 2 Diabetes
Conclusions This study population had overall good adherence to several CDA nutrition therapy guidelines; however, sodium and saturated fat intakes exceeded these guidelines and should receive particular attention in interventions with patients who have type 2 diabetes. Adherence to diabetes dietary guidelines as assessed by PDAQ is associated with lower A1C levels. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - June 23, 2017 Category: Endocrinology Source Type: research

Associations between Sleep Habits and Dysglycemia in US Adults: A Cross-sectional Analysis
Conclusions Between 7 and 8 hours of sleep and fair/poor sleep quality were associated with optimal A1C levels, while sleeping for fewer or more hours appeared to increase dysglycemia, without adjustment for covariates. These relationships were attenuated following multivariable adjustment. Future research is necessary to refine our understanding of the sleep/glycemic-control relationship to provide a context for the clinical significance of these findings for longer-term A1C control in adults with diabetes. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - June 22, 2017 Category: Endocrinology Source Type: research

Can Stem Cells Ameliorate the Pancreatic Damage Induced by Streptozotocin in Rats?
Conclusions Bone marrow–derived MSCs have the capacity to differentiate into IPCs capable of controlling the blood glucose level in rats with STZ-induced diabetes. Furthermore, treatment with MSCs and IPCs can improve aberrant biochemical parameters in an STZ-induced diabetes model. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - June 20, 2017 Category: Endocrinology Source Type: research

Multimorbidity: A Review of the Complexity of Mental Health Issues in Bariatric Surgery Candidates Informed by Canadian Data
Conclusion The healthcare system in Canada is unique, but issues related to prevalence of mental health in patients seeking bariatric surgery are similar to those in studies conducted in other countries. Although data on suicide are lacking, Canadian data have shown similar rates of self-harm behaviours and linkages between psychopathology and weight regain after surgery. Geographic issues that make it difficult for individuals to attend regular follow-up appointments have encouraged the use of e-health tools to engage patients and ensure access to follow-up care, which may provide unique opportunities going forward. Addit...
Source: Canadian Journal of Diabetes - June 14, 2017 Category: Endocrinology Source Type: research

Effects on Diabetes Medications, Weight and A1C Among Patients with Obesity and Diabetes: 6-month Observations From a Full Meal Replacement, Low-Calorie Diet Weight Management Program
Conclusions In patients with obesity and type 2 diabetes taking medications, a full MR-LCD program appears to be safe and includes improvement in A1C levels. At 6 months, the percentage of weight loss can be significantly better in patients who no longer require diabetes medications, and A1C levels are best controlled in patients who are on WN medications. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - June 8, 2017 Category: Endocrinology Source Type: research

So Many Antihyperglycemics: How to Choose? A Practical Approach
Publication date: Available online 7 June 2017 Source:Canadian Journal of Diabetes Author(s): Alice Y.Y. Cheng Guidelines from around the world have stressed the importance of glycemic control in the management of patients with type 2 diabetes (T2DM) to reduce the risk of developing complications. To achieve this goal, both lifestyle and pharmacologic therapies are available. There are 9 classes of antihyperglycemic therapies available in Canada and each class provides a different mechanism of action to address the pathophysiology of T2DM. Metformin remains the first choice for pharmacologic therapy. Thereafter, individua...
Source: Canadian Journal of Diabetes - June 8, 2017 Category: Endocrinology Source Type: research

Prenatal, Obstetric and Perinatal Factors Associated with the Development of Childhood-Onset Type 2 Diabetes
Conclusions Health and social policies and programs are needed to provide financial, educational and clinical resources that target women whose pregnancies are affected by poverty, type 2 diabetes or gestational diabetes. Breastfeeding should be encouraged to aid in the prevention of childhood-onset type 2 diabetes. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - June 3, 2017 Category: Endocrinology Source Type: research

Insights Into the Current Management of Older Adults with Type 2 Diabetes in the Ontario Primary Care Setting
Conclusions Older persons with type 2 diabetes often have multiple comorbidities. Unlike eye and foot examinations, there was less emphasis on evaluating for frailty, cognitive dysfunction and depression. The GOLDEN patients had generally well-controlled glycemic, blood pressure and cholesterol profiles, but whether these would be reflected in a “sicker” population is not known. Personalized strategies are necessary to avoid undertreatment of “healthy” older patients and overtreatment of the frail elderly. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - June 3, 2017 Category: Endocrinology Source Type: research

Expression of Glucose Transporter Proteins in Human Diabetic Placenta
Publication date: Available online 2 June 2017 Source:Canadian Journal of Diabetes Author(s): Paweł Jan Stanirowski, Dariusz Szukiewicz, Monika Pazura-Turowska, Włodzimierz Sawicki, Krzysztof Cendrowski Gestational diabetes mellitus and pregestational diabetes mellitus constitute carbohydrate metabolism disorders, which, if not diagnosed and adequately treated, lead to serious and often life-threatening pregnancy complications. According to a recently formulated hypothesis, some diabetes-related complications, such as fetal macrosomia, may be the result of disturbances in the transplacental transport of nutrients—...
Source: Canadian Journal of Diabetes - June 3, 2017 Category: Endocrinology Source Type: research

Considerations for Initiating a Sodium-Glucose Co-Transporter 2 Inhibitor in Individuals with Type 2 Diabetes Using Insulin
This article reviews the available literature on SGLT2 inhibitor-insulin combination therapy and underscores the issues that should be considered prior to introducing SGLT2 inhibitors to individuals with type 2 diabetes who are already on insulin (with or without other antihyperglycemic agents) to ensure individualization of therapy. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - June 1, 2017 Category: Endocrinology Source Type: research

Comorbid Conditions in Canadians Hospitalized Because of Diabetes
Conclusions Hospitalizations resulting from diabetes are associated with vascular comorbidities, and hypertension is the most common. Prevention of shared predisposing factors should reduce the burden of hospitalizations associated with diabetes. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - June 1, 2017 Category: Endocrinology Source Type: research

The Gut Microbiota as a Mediator of Metabolic Benefits after Bariatric Surgery
Publication date: Available online 25 May 2017 Source:Canadian Journal of Diabetes Author(s): Fernando F. Anhê, Thibault V. Varin, Jonathan D. Schertzer, André Marette Bariatric surgery is based on major anatomic rearrangements in the gastrointestinal tract that coincide with functional and taxonomic changes in gut microbial communities. These alterations in gut anatomy and in the microbiota are associated with early resolution of obesity-related impairment of glycemic control and are marked weight loss in the long term. Moreover, altered bile acid metabolism has been implicated in the control of energy homeo...
Source: Canadian Journal of Diabetes - May 26, 2017 Category: Endocrinology Source Type: research

Blood Pressure Management in Patients with Diabetes: Insights From the Diabetes Mellitus Status in Canada Survey
Conclusions Only about one-third of patients with diabetes achieved the target BP of below 130/80 mmHg. Patients with BP 130/80 mmHg or higher were also less likely to achieve optimal guideline-recommended glycated hemoglobin and low-density lipoprotein-cholesterol targets. Improved comprehensive management of all risk factors in patients with diabetes is warranted. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 26, 2017 Category: Endocrinology Source Type: research

Association of Sympathovagal Imbalance with Cognitive Impairment in Type 2 Diabetes
Conclusion Treatment-naïve patients with type 2 diabetes have SVI and considerable cognitive impairment. Insulin resistance and oxidative stress contribute to cognitive impairment, and SVI could be the physiologic link to cognitive impairment in treatment-naïve patients with type 2 diabetes. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 25, 2017 Category: Endocrinology Source Type: research

Patient Perspectives on Diabetes Care Across the Institute of Medicine's Six Domains of Quality
Conclusion Patients' views of high-quality diabetes care include all 6 domains of quality with a stronger emphasis on safe, effective and patient-centred care. Future evaluation of diabetes programs should incorporate a comprehensive and patient-informed approach to consideration of what constitutes high-quality care. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 24, 2017 Category: Endocrinology Source Type: research

The iSCREEN Electronic Diabetes Dashboard: A Tool to Improve Knowledge and Implementation of Clinical Practice Guidelines
Conclusions Implementation of a de novo CDSS was associated with improved rates of appropriate screening for diabetes-related complications. A trend toward improvement in health professionals' knowledge of the guidelines was also observed. Evaluation of this point-of-care computerized decision support tool suggests that it may facilitate diabetes care by optimizing complication screening and CPG knowledge, with the potential for broader implementation. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 24, 2017 Category: Endocrinology Source Type: research

Epidemiology of Cerebrovascular Disease among Chinese Canadians with Diabetes
Conclusion Chinese Canadians with diabetes who had ischemic strokes were especially susceptible to intracranial small vessel disease compared with non-Chinese Canadians. These results signify that risk factor prevalence and stroke types differ considerably between Chinese Canadians and non-Chinese Canadians residing in Toronto, warranting further study. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 24, 2017 Category: Endocrinology Source Type: research

The Canadian Hypoglycemia Assessment Tool Program: Insights Into Rates and Implications of Hypoglycemia From an Observational Study
Conclusions Prevalence and incidence of hypoglycemia were high among insulin-treated patients with diabetes in Canada, and some patients took harmful or costly actions when they experienced hypoglycemia. Identifying the insulin-treated patients who are at greatest risk may help to reduce the incidence of hypoglycemia. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 18, 2017 Category: Endocrinology Source Type: research

The Effects of Natural Clinoptilolite and Nano-Sized Clinoptilolite Supplementation on Glucose Levels and Oxidative Stress in Rats with Streptozotocin-Induced Diabetes
Conclusion Nano-sized clinoptilolite exerted a hypoglycemic effect in streptozotocin-induced diabetic rats but had no significant influence on oxidative stress markers. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 13, 2017 Category: Endocrinology Source Type: research

The Relationship between Type 2 Diabetes and Breast Cancer Incidence in Differing Ethnic Groups
Publication date: Available online 12 May 2017 Source:Canadian Journal of Diabetes Author(s): Gertraud Maskarinec, Angelique Fontaine, Johanna Eyrun Torfadottir, Lorraine L. Lipscombe, Iliana C. Lega, Jonine Figueroa, Sarah Wild In addition to rising type 2 diabetes and breast cancer incidence rates worldwide, diabetes may also increase breast cancer risk, and the association may vary by ethnicity. This review summarizes published data evaluating the association between diabetes and breast cancer in women of Asian, Hispanic and African American ancestry while considering a measure of obesity, body mass index (BMI). Publis...
Source: Canadian Journal of Diabetes - May 13, 2017 Category: Endocrinology Source Type: research

Postpartum Diabetes Testing Rates after Gestational Diabetes Mellitus in Canadian Women: A Population-Based Study
Conclusions Despite a universal health-care system in Canada, many women with IGTp or GDM do not undergo postpartum glucose testing. Maternal and pregnancy characteristics influence postpartum testing and provide valuable information for creating targeted strategies to improve postpartum testing in this group of high-risk women. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 13, 2017 Category: Endocrinology Source Type: research

Association between the Polymorphism of Glu298Asp in Exon 7 of the eNOS Gene with Foot Ulcer and Oxidative Stress in Patients with Type 2 Diabetes
Conclusions These results imply that the T allele might be protective against DFU. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 10, 2017 Category: Endocrinology Source Type: research

Self-Monitoring Blood Glucose Test Strip Utilization in Saskatchewan: A Retrospective Study
Conclusions If Saskatchewan's newly imposed coverage limits had been applied in 2013, the costs of strips exceeding those limits would have totalled $2.5 million. Although TS use aligns with chronic disease care paradigms, the substantial costs and lack of evidence of patient outcomes demand better strategies to help reduce unnecessary use. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 9, 2017 Category: Endocrinology Source Type: research

Nocturia and Prevalence of Depressive Symptoms in Japanese Patients with Type 2 Diabetes Mellitus: The Dogo Study
Conclusions In Japanese female patients with type 2 diabetes, nocturia may be positively associated with depressive symptoms. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 9, 2017 Category: Endocrinology Source Type: research

The Relationship between 25-hydroxyvitamin D Levels, Insulin Sensitivity and Insulin Secretion in Women 3 Years after Delivery
Conclusions Prior GDM status was not associated with 25(OH)D levels; however, 25(OH) D levels were associated with HOMA insulin sensitivity. It is hypothesized that the association between HOMA insulin secretion and 25(OH)D levels is related to the autoregulation of fasting glucose levels because no association between 25(OH)D and insulinogenic index was found. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 3, 2017 Category: Endocrinology Source Type: research

A Qualitative Study of Young Adult Experiences in the Bariatric Healthcare System: Psychosocial Challenges and Developmental Difficulties
Conclusions Results revealed that patients' experiences appear to encompass impact on familial relationships, needs sought to be fulfilled by healthcare providers, and various preoperative and postoperative psychosocial concerns. By understanding the experiences of young adults, healthcare providers might be able to provide better care for these patients. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 2, 2017 Category: Endocrinology Source Type: research