183 - Effect of Ivacaftor on Pancreatic Endocrine Function
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5, SupplementAuthor(s): Nada Alhashemi, Julie Gilmour, Jenna Sykes, Elizabeth Tullis (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

184 - Case Report: Metastatic Papillary Thyroid Cancer Presenting with a Recurrent Necrotic Cystic Cervical Lymph Node
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5, SupplementAuthor(s): Alexa Clark, Marosh Manduch, Russell Hollins, Sara Awad (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

2018 Appendix: Duality of Interest Disclosures
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5, SupplementAuthor(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Masthead
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Table of Contents
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Editorial Board
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

The Role of Mainstream Publishers in Eliminating the Threat of Predatory Publishing
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): Abin Chandrakumar, Geert Willem ‘t Jong, Terry P. Klassen (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

The Prevalence and Risk for Herpes Zoster Infection in Adult Patients With Diabetes Mellitus in the Canadian Primary Care Sentinel Surveillance Network
ConclusionsPeople with diabetes have an increased risk for the diagnosis of HZ infection in the primary care setting in Canada. Women over the age of 65 years with diabetes and/or other chronic conditions are at greatest risk for developing HZ.RésuméObjectifsL'herpès zoster (HZ) qui est une infection fréquente au Canada peut entraîner des complications sérieuses et à long terme. Les personnes diabétiques peuvent être exposées à un risque accru de HZ. Les objectifs de la présente étude étaient d'élaborer et de valider une ...
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Evaluating the Impact of Diabetes Self-Management Education Methods on Knowledge, Attitudes and Behaviours of Adult Patients With Type 2 Diabetes Mellitus
ConclusionsCMs had a significant impact and are effective for group education. The changes observed may lead to improved diabetes self-management, thus reducing costly health complications related to poorly controlled diabetes.RésuméObjectifsLa prise en charge autonome du diabète concerne toutes les actions que les patients entreprennent pour prendre soin de leur maladie, préserver la santé et prévenir les conséquences du diabète à court et à long terme. C'est par l'étude des changements dans les concentrations de l'hémoglobine glyqué...
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Early-Onset Physical Frailty in Adults With Diabesity and Peripheral Neuropathy
ConclusionsIndividuals with diabesity and peripheral neuropathy are particularly likely to be classified as frail. Earlier identification and interventions aimed at improving lower-extremity function may be important to mitigate the early-onset functional decline.RésuméObjectifsIl a été reconnu que la diabésité (obésité et diabète sucré) contribue à l'apparition précoce de la fragilité. On ne comprend pas bien les troubles qui contribuent à l'apparition précoce de la fragilité physique dans cette population. De p...
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Dietary Intakes of Branched-Chained Amino Acid and Risk for Type 2 Diabetes in Adults: The Harbin Cohort Study on Diet, Nutrition and Chronic Non-Communicable Diseases Study
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): Akinkunmi Paul Okekunle, Xiaoyan Wu, Wei Duan, Rennan Feng, Ying Li, Changhao SunAbstractObjectivesTo assess the association between branched-chain amino acid (BCAA) intakes and risk for type 2 diabetes.MethodsDietary intakes were assessed in 1,804 people with type 2 diabetes and 7,020 controls with information on nutrient intakes, including BCAAs derived from Chinese food composition tables. Principal component analysis was used to identify dietary patterns (DPs) and multivariable-adjusted odds ratios (ORs) of type 2 diabetes,...
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Effectiveness of a Type 2 Diabetes Screening Intervention in the Canadian Workplace
ConclusionsThis study provides a framework for future diabetes interventions in the workplace and demonstrates that workplace interventions may reduce employees' diabetes risk levels and are valued by employees.RésuméObjectifsLes données canadiennes sur l'efficacité des interventions en matière de diabète en milieu de travail sont insuffisantes. La présente étude, qui avait pour objectif de mieux informer les intervenants en milieu de travail, a porté sur l'évaluation de l'efficacité de Motivaction, un programme pilote de dépistage et d'ens...
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Gestational Diabetes Mellitus: Using the Fasting Plasma Glucose Level to Simplify the International Association of Diabetes and Pregnancy Study Groups Diagnostic Algorithm in an Adult South Asian Population
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): Mukesh M. Agarwal, John Punnose, Komal Sukhija, Asha Sharma, Naimaa K. ChoudharyAbstractObjectivesTo evaluate the value of the fasting plasma glucose (FPG) level for simplifying the International Association of Diabetes and Pregnancy Study Groups (IADPSG) diagnostic algorithm of gestational diabetes mellitus (GDM) in a South Asian population.MethodsIn 6,520 pregnant women undergoing universal screening with the 75 g oral glucose tolerance test (OGTT), the area under receiver operating characteristic curve was used to det...
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Effectiveness of an Interprofessional Glycemic Optimization Clinic on Preoperative Glycated Hemoglobin Levels for Adult Patients With Type 2 Diabetes Undergoing Bariatric Surgery
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): Robyn L. Houlden, Joy L. Yen, Sarah MooreAbstractObjectivesBariatric surgery is an effective treatment for patients with type 2 diabetes and refractory obesity; however, many patients have nonoptimal glycemic control preoperatively. We created an interprofessional bariatric glycemic optimization clinic. Patients were seen monthly and received weekly phone calls. We analyzed the effectiveness in assisting patients reach a preoperative glycated hemoglobin (A1C) level of
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

A Landscape of Bariatric Surgery in Canada: For the Treatment of Obesity, Type 2 Diabetes and Other Comorbidities in Adults
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): Mehran Anvari, Rodrigo Lemus, Ruth BreauAbstractObesity has escalated worldwide and in Canada. Many chronic conditions, including type 2 diabetes, are directly correlated with obesity, and although the benefits and effectiveness of bariatric surgery have been proven in terms of sustained weight loss and improving comorbidities, the procedure is underaccessed and underutilized in Canada. We explored the complex landscape of bariatric surgery in Canada, reviewing the current state and focusing on the volume of procedures nationwi...
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Erratum to “Dyslipidemia”: Canadian Journal of Diabetes 2018;42(S1):S178-S185
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): G.B. John Mancini, Robert A. Hegele, Lawrence A. Leiter (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Erratum to “Pharmacologic Glycemic Management of Type 2 Diabetes in Adults”: Canadian Journal of Diabetes 2018;42(S1):S88-S103
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): Lorraine Lipscombe, Gillian Booth, Sonia Butalia, Kaberi Dasgupta, Dean T. Eurich, Ronald Goldenberg, Nadia Khan, Lori MacCallum, Baiju R. Shah, Scot Simpson (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Erratum to “Glycemic Management in Adults With Type 1 Diabetes”: Canadian Journal of Diabetes 2018;42(S1):S80-S87
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5Author(s): Angela McGibbon, Lenley Adams, Karen Ingersoll, Tina Kader, Barna Tugwell (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

134 - Withdrawn
Publication date: October 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 5, SupplementAuthor(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - October 5, 2018 Category: Endocrinology Source Type: research

Adjustment for Waist Circumference Reveals a U-Shaped Association between HbA1c and Body Mass Index in Young Adults
Publication date: Available online 21 September 2018Source: Canadian Journal of DiabetesAuthor(s): Ryoko Higuchi, Taizo Iwane, Kaname Suwa, Kei NakajimaAbstractPurposeBody mass index (BMI) is used to assess adiposity worldwide. However, additional adjustment for waist circumference (WC), a surrogate marker of abdominal fat, may be capable of revealing a latent relationship between low body weight and glycated hemoglobin (HbA1c) concentration. Here, we investigated the relationship between HbA1c and BMI in young adults, adjusting for WC.MethodsWe reviewed HbA1c, BMI, WC, and other clinical data in a cross-sectional study of...
Source: Canadian Journal of Diabetes - September 22, 2018 Category: Endocrinology Source Type: research

Patient Assessment of Family Function, Glycemic Control and Quality-of-Life in Patients with Type 2 Diabetes with Incipient Complications.
Publication date: Available online 17 September 2018Source: Canadian Journal of DiabetesAuthor(s): Birgitte B. Bennich, Lene Munch, Ingrid Egerod, Hanne Konradsen, Steen Ladelund, Filip K. Knop, Tina Vilsbøll, Michael Røder, Dorthe OvergaardAbstractObjectivesThe family affects the perception of diabetes self-management in patients with diabetes. Family-related questionnaires have been used to assess the family function, but the Brief Family Assessment Measure (Brief FAM-III), has not previously been used in a diabetes population. We aimed to determine whether the family function is associated with glycated he...
Source: Canadian Journal of Diabetes - September 18, 2018 Category: Endocrinology Source Type: research

Combination Therapy with GLP-1 Receptor Agonists and SGLT-2 Inhibitors in Older Patients with Type 2 Diabetes: a Real-World Evidence Study
Publication date: Available online 8 September 2018Source: Canadian Journal of DiabetesAuthor(s): Juana Carretero Gómez, José Carlos Arévalo Lorido, Ricardo Gómez Huelgas, Dolores García de Lucas, Lourdes Mateos Polo, José Manuel Varela Aguilar, Jose Miguel Seguí Ripoll, Javier Ena, Diabetes, Obesity, and Nutrition Spanish Working GroupAbstractBackgroundscientific literature about the combination of GLP1ras and SGLT2i in older patient is scarce.AimsAssess the real-world efficacy and safety of SGLT2inhibitors and GLP-1ras combination therapy among older patients (> 65 year...
Source: Canadian Journal of Diabetes - September 8, 2018 Category: Endocrinology Source Type: research

Insulin-treated diabetes and driving: legal jeopardy and consequences of hypoglycemia
Publication date: Available online 6 September 2018Source: Canadian Journal of DiabetesAuthor(s): Ian Blumer, Anne B. Kenshole, Jacob Stilman, Gary F. Lewis (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - September 6, 2018 Category: Endocrinology Source Type: research

Cystic Fibrosis-Related Diabetes Screening in Adults: A Gap Analysis and Evaluation of Accuracy of Glycated Hemoglobin Levels
Publication date: Available online 2 May 2018Source: Canadian Journal of DiabetesAuthor(s): Julie A. Gilmour, Jenna Sykes, Edward Etchells, Elizabeth TullisAbstractObjectivesWe sought to identify the gap in cystic fibrosis-related diabetes (CFRD) screening by means of an oral glucose tolerance test (OGTT) in our tertiary care clinic. Our second aim was to identify the glycated hemoglobin level (A1C) threshold that optimizes sensitivity and specificity for predicting CFRD and impaired glucose tolerance.MethodsThis retrospective study used data housed in the Toronto cystic fibrosis (CF) database. The study population include...
Source: Canadian Journal of Diabetes - September 2, 2018 Category: Endocrinology Source Type: research

Effect of Aerobic and Resistance Exercise on Glycemic Control in Adults with Type 1 Diabetes
Publication date: Available online 30 August 2018Source: Canadian Journal of DiabetesAuthor(s): Ravi Reddy, Amanda Wittenberg, Jessica R. Castle, Joseph El Youssef, Kerri Winters-Stone, Melanie Gillingham, Peter G. JacobsStructured AbstractAimsPhysical exercise is recommended to individuals with type 1 diabetes (T1D) yet the effects of exercise on glycemic control have not been well-established. We evaluated the impact of different modes of exercise on glycemic control in people with T1D.MethodsIn a 3-week randomized crossover trial, 10 adults with T1D (4 M, 6 F; age 33 ± 6 yrs, duration of diabetes 18 ± 10 y...
Source: Canadian Journal of Diabetes - September 1, 2018 Category: Endocrinology Source Type: research

The relationship between increased ratio of visceral-to-subcutaneous fat area and renal outcome in Chinese adult with type 2 diabetes and diabetic kidney disease
Publication date: Available online 25 August 2018Source: Canadian Journal of DiabetesAuthor(s): Yiting Wang, Feng Chen, Jiali Wang, Tingli Wang, Junlin Zhang, Qianqian Han, Yucheng Wu, RuiFang ZhangLiuAbstractAimThe abdominal obesity is the risk factor of diabetes, hypertension. The study aimed to investigate the association between excessive abdominal fat and renal outcome in patients with type 2 diabetes and diabetic kidney disease (DKD).MethodsA total of 35 DKD patients with type 2 diabetes mellitus who received follow-up for at least one year were enrolled. Visceral fat area (VFA) and subcutaneous fat area (SFA) were a...
Source: Canadian Journal of Diabetes - August 26, 2018 Category: Endocrinology Source Type: research

High Proportion of Adults With Type 2 Diabetes and Poor Glycated Hemoglobin Perceived That Their Diabetes Control Was Excellent
ConclusionsThis study demonstrated discordance between perceived diabetes control and actual A1C levels, which may hinder effective diabetes care.RésuméObjectifsTout comme les autres maladies de longue durée, la perception de lutte contre la maladie est essentielle à l'autonomisation des patients dans les soins du diabète. La présente étude vise à décrire la perception qu'ont les patients ayant de faibles concentrations d'hémoglobine glyquée (A1c) sur la lutte contre le diabète pour étudier la relation entre la perception et les nomb...
Source: Canadian Journal of Diabetes - August 23, 2018 Category: Endocrinology Source Type: research

Frailty, Health-Related Quality of Life, Cognition, Depression, Vitamin D and Health-Care Utilization in an Ambulatory Adult Population with Type 1 or Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Cross-Sectional Analysis
Publication date: Available online 20 June 2018Source: Canadian Journal of DiabetesAuthor(s): Stephany I. Adame Perez, Peter A. Senior, Catherine J. Field, Kailash Jindal, Diana R. MagerAbstractObjectivesFrailty can cause increased vulnerability to adverse health outcomes, such as falls, fractures, depression and reduced health-related quality of life (HRQoL). This cross-sectional study compared the differences in body composition, HRQoL, mental health and cognitive and vitamin D (vitD) status with health-care utilization by frail and nonfrail adults with diabetes mellitus (type 1 and type 2) and with chronic kidney diseas...
Source: Canadian Journal of Diabetes - August 21, 2018 Category: Endocrinology Source Type: research

End of Life: What Does That Mean for the Management of Adult Patients With Type 1 Diabetes?
Publication date: Available online 20 June 2018Source: Canadian Journal of DiabetesAuthor(s): Jill Trinacty, Erin Keely (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 18, 2018 Category: Endocrinology Source Type: research

Evaluation of a Patient-Care Planning Intervention to Improve Appointment Attendance by Adults After Bariatric Surgery
ConclusionsIn summary, this quality-improvement intervention was able to improve patient-centred care and clinic efficiency through the use of advance-care planning as evaluated by appointment attendance data and patient satisfaction surveys.RésuméObjectifsLa chirurgie bariatrique s'est avérée un traitement durable de l'obésité grave. Toutefois, les taux élevés d'absence et l'engagement des patients au cours de la période postopératoire posent problème. La présente étude qui porte sur les périodes préopératoire e...
Source: Canadian Journal of Diabetes - August 17, 2018 Category: Endocrinology Source Type: research

Development and Implementation of a DKA Protocol for Adults with Type 1 and Type 2 Diabetes at a Tertiary Care Multi-Campus Hospital
ConclusionsSuccessful implementation of a standardized pre-printed protocol for DKA management significantly improved best practices for DKA management and was valued by treating clinicians. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 17, 2018 Category: Endocrinology Source Type: research

Analysis of Trends in Insulin Utilization and Spending Across Canada From 2010 to 2015
ConclusionOverall, the rate of uptake of long-acting insulins has increased nationally. Uptake varied widely between provinces and is likely associated with differential cost increases across public-payers in Canada. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 17, 2018 Category: Endocrinology Source Type: research

Derivation and Validation of a Risk Prediction Tool for Hypoglycemia in Hospitalized Adults with Diabetes: the Hypoglycemia during Hospitalization (HyDHo) Score
ConclusionsA parsimonious risk prediction model that uses five key clinical variables predicts hypoglycemia during hospitalization at the time of admission. More than one-quarter of patients at low risk of hypoglycemia had a score below the threshold. They could be identified at the time of admission by applying the HyDHo Score, and may need less intensive glucose monitoring in hospital. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 11, 2018 Category: Endocrinology Source Type: research

Process Evaluation of the Canadian Diabetes Association Guidelines Dissemination Strategy Using the RE-AIM Framework
ConclusionsOur interactive tools were highly and repeatedly accessed, signifying its relevance to problems in clinical care. Our synthesized analyses indicate the guidelines website to be resource-intensive with a wide reach and a potential to change outcomes. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 11, 2018 Category: Endocrinology Source Type: research

A Comparison of Structured Education Programs for Pediatric Type 1 Diabetes: Multiple Daily Injection (MDI) Therapy Delivered by Group Workshop Versus Self-Study Course
Publication date: Available online 9 August 2018Source: Canadian Journal of DiabetesAuthor(s): Karen Johnston, Gloria Johnston, Elizabeth Rosolowsky (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 9, 2018 Category: Endocrinology Source Type: research

Intercellular adhesion molecule-1 (ICAM-1) Lys469Glu polymorphism, systemic redox homeostasis and gestational diabetes mellitus
ConclusionAlthough no significant difference was observed between genotypes, oxidative damage observed in patients with GDM warrants earlier screening and management in the light of new evidence. (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - August 2, 2018 Category: Endocrinology Source Type: research

Lived Experience as a Distinct Information Source: A Case Study to Improve E-Health Products for Adults With Type 1 or 2 Diabetes Starting Insulin
Publication date: August 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 4Author(s): Jennica Nichols, Stephanie Boutette, Krista Banasiak (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Masthead
Publication date: August 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 4Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Table of Contents
Publication date: August 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 4Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Editorial Board
Publication date: August 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 4Author(s): (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

In This Issue…
Publication date: August 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 4Author(s): Elizabeth Sellers (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Effects of Diabetes Mellitus on Cognitive Decline in Patients With Alzheimer Disease
Publication date: August 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 4Author(s): Tomoyuki Kawada (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

The Mountain of Health: The Perceptions and Perceived Expectations of Youth Living With Type 2 Diabetes in Winnipeg, Manitoba, Canada, Through a Grounded Theory Study
ConclusionFuture interventionists should be aware of the vast incongruence in patients' perceptions of health in type 2 diabetes and their perceptions of health-care providers' expectations during the development of interventions.RésuméObjectifL'objectif de la présente étude était d'examiner la perception des jeunes à l'égard de la prise en charge du diabète.MéthodesL'étude comptait 8 jeunes Manitobains atteints du diabète de type 2 (n=7 filles). Chaque jeune a participé à une entrevue semi-structurée en personne, par Skype ou...
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Development of Perinatal Mental Illness in Women With Gestational Diabetes Mellitus: A Population-Based Cohort Study
ConclusionsIn this large population-based cohort of women in Alberta, GDM was not associated with an increased risk for developing new-onset mental illness during pregnancy or postpartum.RésuméObjectifsExaminer la relation entre le diabète sucré gestationnel (DSG) et le développement de la maladie mentale (troubles affectifs et anxieux) au cours de la grossesse et dans l'année qui suit l'accouchement.MéthodesNous avons relié les bases de données cliniques et administratives pour repérer les diagnostics de DSG et de maladie mentale chez les mères q...
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Effect of Ruta chalepensis on Zinc, Lipid Profile and Antioxidant Levels in the Blood and Tissue of Streptozotocin-Induced Diabetes in Rats Fed Zinc-Deficient Diets
ConclusionsIt seems that R. chalepensis supplementation is a potent factor in reducing the oxidative severity of zinc deficiency in experimental diabetes through its hypoglycemic and antioxidant actions.RésuméObjectifsLors de diabète, le stress oxydatif et les anomalies lipidiques sont fréquents et prononcés, et représentent les facteurs importants qui participent à l'apparition des complications du diabète. La carence en zinc induit généralement un stress oxydatif. Lors de maladies métaboliques, l'antioxydant Ruta chalepensis estbien connu pour s...
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Optimizing Glycemic Control in Adults With Type 1 or Type 2 Diabetes Attending a Multidisciplinary Foot Clinic
Publication date: August 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 4Author(s): Devin Betsch, Zhiwei Gao, Gerry Mugford, Susan McGrath-Terry, Gordon DowAbstractObjectivesTo determine the impact of a diabetes nurse educator (DNE) on glycemic control in a multidisciplinary diabetes foot (MDF) clinic.MethodsA prospective cohort trial to measure the impact of a DNE on glycemic control was conducted in an MDF clinic. Change in glycated hemoglobin (A1C) levels over time was measured against the percentage of patient visits (PPVs) accompanied by a glucose meter and/or diary.ResultsIncreasing PPVs were significantl...
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Symptoms of Mental Illness and Their Impact on Managing Type 2 Diabetes in Adults
ConclusionsMultidimensional diabetes education programs that consider psychological, physical and social challenges are needed to address the needs of people with mental illnesses.RésuméObjectifsLes personnes atteintes de maladies mentales sont plus exposées aux complications du diabète susceptibles de réduire l'espérance de vie de 10 à 15 ans. Il est possible d'améliorer la prise en charge du diabète et les résultats cliniques lorsque les interventions sur le mode de vie portent sur des habitudes alimentaires saines et que l'activité physique uti...
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Plasma Palmitoyl-Carnitine (AC16:0) Is a Marker of Increased Postprandial Nonesterified Incomplete Fatty Acid Oxidation Rate in Adults With Type 2 Diabetes
Publication date: August 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 4Author(s): Fatima-Zahra Bouchouirab, Mélanie Fortin, Christophe Noll, Jean Dubé, André C. CarpentierAbstractObjectivesEnhanced mitochondrial fatty acid utilization is known to increase radical oxidative stress and induce insulin resistance. An increased level of plasma acylcarnitine (AC) has been proposed to indicate mitochondrial energy substrate overload, a possible mechanism leading to insulin resistance. The aim of our study was to determine fasting and postprandial plasma acetyl-carnitine (AC2:0), palmitoyl-carnit...
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

A Canadian Cross-Sectional Survey on Psychosocial Supports for Adults Living With Type 1 or 2 Diabetes: Health-Care Providers' Awareness, Capacity and Motivation
ConclusionsMotivation to address psychosocial issues in diabetes was high, but capacity to do so and opportunity to learn how were both low. These findings can be used to develop a targeted strategy to help address this gap.RésuméObjectifsRésoudre les problèmes psychosociaux est essentiel à la prise en charge autonome du diabète. Ces travaux portent sur : 1) la perception des professionnels de la santé (PS) quant à la pertinence des divers problèmes psychosociaux dans la prise en charge du diabète; 2) la confiance qu'ont les PS de travailler sur ces prob...
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research

Is YouTube Useful as a Source of Health Information for Adults With Type 2 Diabetes? A South Asian Perspective
Publication date: August 2018Source: Canadian Journal of Diabetes, Volume 42, Issue 4Author(s): Amanda Y. Leong, Ravina Sanghera, Jaspreet Jhajj, Nandini Desai, Bikramjit Singh Jammu, Mark J. MakowskyAbstractObjectivesTo investigate the content, quality and popularity of information about type 2 diabetes available on YouTube.MethodsWe searched YouTube with the terms Diabetes, Diabetes type 2, Diabetes South Asians, Diabetes Punjabi and Diabetes Hindi to identify videos concerning type 2 diabetes. A team of health-care providers independently classified the first 20 videos from each search as useful, misleading, or personal...
Source: Canadian Journal of Diabetes - July 31, 2018 Category: Endocrinology Source Type: research