Exposure levels and target attainment of piperacillin/tazobactam in adult patients admitted to the intensive care unit: a prospective observational study
ConclusionIn this prospective observational study of adult ICU patients receiving intravenous PTZ, a large proportion had subtherapeutic concentrations of piperacillin. This was most notable in patients with normal to augmented renal clearance. More aggressive dosage regimens may be required for this subpopulation to ensure attainment of efficacy targets. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 19, 2024 Category: Anesthesiology Source Type: research
Perioperative copeptin: predictive value and risk stratification in patients undergoing major noncardiac surgery —a prospective observational cohort study
ConclusionThe results of the present prospective observational cohort study suggest that perioperative copeptin concentrations can help identify patients at risk for all-cause mortality and/or MACCE. Other identified risk factors were revised cardiac risk index, body mass index, surgical risk, and preoperative hemoglobin.Trial registrationClinicalTrials.gov (NCT02687776); first submitted 9 February 2016. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 19, 2024 Category: Anesthesiology Source Type: research
Are we closer to determining a gold standard for sensory block testing during labour epidural analgesia?
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 19, 2024 Category: Anesthesiology Source Type: research
A comparative evaluation of fibreoptic bronchoscopy versus C-MAC ® D-BLADE-guided videolaryngoscopy for nasotracheal intubation under general anesthesia in oropharyngeal carcinoma surgery patients
ConclusionCompared to FB, C-MAC D-BLADE-based VL reduced the total time for nasal intubation oropharyngeal carcinoma patients, potentially representing an acceptable alternative in selected cases.Trial registrationCTRI.nic.in (2018/11/0162830); first submitted 8 November 2018. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 19, 2024 Category: Anesthesiology Source Type: research
Severe dural ectasia in a pregnant patient with Marfan syndrome
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 19, 2024 Category: Anesthesiology Source Type: research
Parallel intubation technique with the Vie Scope ® laryngoscope
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 19, 2024 Category: Anesthesiology Source Type: research
In reply: Parallel intubation technique with the Vie Scope ® laryngoscope
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 19, 2024 Category: Anesthesiology Source Type: research
Bolus-only bivalirudin for carotid endarterectomy in a patient with heparin-induced thrombocytopenia
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 12, 2024 Category: Anesthesiology Source Type: research
Intraoperative cloudy urine due to propofol-induced crystallization of uric acid
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 10, 2024 Category: Anesthesiology Source Type: research
Effect of using smaller blood volume tubes and closed blood collection devices on total blood loss in patients undergoing major cardiac and vascular surgery
ConclusionDiagnostic laboratory tests are associated with significant patient blood loss, but are a modifiable risk factor. The use of small-volume tubes and closed blood collection devices decreases the volume of patient blood drawn for analysis and prevents blood waste. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 8, 2024 Category: Anesthesiology Source Type: research
Preoperative anemia in older individuals undergoing major abdominal surgery is associated with early postoperative morbidity: a prospective observational study
ConclusionAnemia is significantly associated with poorer postoperative outcomes in the older population. The impact of anemia on postoperative outcomes could be further evaluated with quality of life indicators, patient-reported outcome measures, and health economic tools. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 5, 2024 Category: Anesthesiology Source Type: research
Perioperative quality indicators specific to the practice of anesthesia in noncardiac surgery: an umbrella review
ConclusionThis umbrella review highlights the scarcity of perioperative quality indicators that are supported by high quality evidence. Future development of quality indicators and recommendations for outcome measurement should focus on metrics that are supported by level 1 evidence. Potential targets for evidence-based quality-improvement programs in anesthesia are identified herein.Study registrationPROSPERO (CRD42020164691); first registered 28 April 2020. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - January 5, 2024 Category: Anesthesiology Source Type: research
