General anesthesia for Cesarean delivery: can interinstitutional variation in practice offer deeper insights into our choice of anesthetic modality?
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 6, 2023 Category: Anesthesiology Source Type: research

Preoperative anemia and anemia treatment in cardiac surgery: a systematic review and meta-analysis
ConclusionsPreoperative anemia is associated with mortality and morbidity after cardiac surgery. More research is warranted to test the efficacy of current anemia treatment programs.Study registrationPROSPERO (CRD42022319431); first submitted 17 April 2023. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 6, 2023 Category: Anesthesiology Source Type: research

Functional recovery of wrist surgery with regional versus general anesthesia: a prospective observational study
ConclusionRegional anesthesia was not associated with improved functional recovery compared with general anesthesia. The dominance of the operated limb was a confusion factor in all evaluation modalities. Further research taking into account the dominance of the hand is necessary to establish the effects of regional anesthesia on functional recovery.Study registrationClinicalTrials.gov (NCT04541745); registered 9 September 2020. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 6, 2023 Category: Anesthesiology Source Type: research

Inflammatory changes in the plasma and cerebrospinal fluid of patients with persistent pain and postpartum depression after elective Cesarean delivery: an exploratory prospective cohort study
ConclusionsWe observed differential levels of plasma and CSF inflammatory biomarkers in patients who developed persistent pain and PPD compared with those who did not. We showed the feasibility of collecting plasma and CSF samples at Cesarean delivery, which may prove useful for future risk-stratification.Study registrationClinicalTrials.gov (NCT04271072); registered 17 February 2020. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 6, 2023 Category: Anesthesiology Source Type: research

Unanticipated difficult intubation due to a deformed cricoid cartilage ring from 20-year-old trauma
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 6, 2023 Category: Anesthesiology Source Type: research

Accuracy of the Nova StatStrip ® glucometer in patients undergoing major abdominal surgery: an observational study
ConclusionThe Nova StatStrip glucometer was accurate in patients undergoing major upper abdominal surgery, independent of the administration of high-dose insulin therapy.Study registrationClinicalTrials.gov (NCT01528189); registered 7 February 2012. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research

Association between postoperative hypotension and acute kidney injury after noncardiac surgery: a historical cohort analysis
ConclusionPostoperative hypotension, defined as the lowest postoperative mean arterial pressure<  80 mm Hg, was associated with acute kidney injury after noncardiac surgery. A prospective trial will be required to determine whether the observed association is causal and thus amenable to modification. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research

Interventional pain blocks in Ontario: a population-based cross-sectional study on 2019 procedural volumes, clustering, and physician billings
ConclusionPain block administration is highly clustered in Ontario, with many patients receiving PBs in ways that are not supported by best evidence. Further research is required to determine whether the Ontario fee-for-service model of billing has created a suboptimal use of these health care resources. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research

Regional anesthesia and analgesia in patients with spastic cerebral palsy undergoing orthopedic surgery: a historical cohort study
ConclusionDespite the use of regional anesthesia, approximately 15% of patients with spastic CP undergoing orthopedic surgery for spastic cerebral palsy experienced severe pain that responded to treatment adjustments.Study registrationCTRI.nic.in (027002); registered 5 August 2020. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research

The association of intraoperative opioid dose with postanesthesia care unit outcomes in children: a retrospective study
ConclusionsChildren who received lower doses of intraoperative opioids did not have worse PACU pain outcomes but required fewer antiemetics and received greater numbers of nonopioid analgesics intraoperatively. These findings suggest that lower doses of intraoperative opioids may be administered to children as long as other analgesics are used. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research

Prevention of postoperative atrial fibrillation in cardiac surgery: a quality improvement project
ConclusionsThis single-centre QI intervention increased the use of prophylactic amiodarone by 28% for patients at elevated risk of POAF, with no change in the early postoperative initiation of beta blockers (46.7% of patients by POD1). There was a notable reduction in the incidence of POAF in patients at elevated risk undergoing surgery. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research

Higher portal venous pulsatility is associated with worse clinical outcomes following congenital heart surgery: a single-centre prospective cohort study
ConclusionsHigher portal venous pulsatility is associated with major postoperative complications in children undergoing cardiac surgery. Nevertheless, more data are needed to conclude the efficacy of portal venous pulsatility in patients with univentricular physiology.Study registrationClinicalTrials.gov (NCT03990779); registered 19 June 2019. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research

Motivations and demographic differences in pregnant individuals in the decision to participate in research
ConclusionsThese findings can help identify areas for improvement of participation of pregnant individuals in research studies.  Demographic associations may influence participation and reasons for participation. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research

Landiolol for the prevention of postoperative atrial fibrillation after cardiac surgery: a systematic review and meta-analysis
ConclusionIn patients undergoing cardiac surgery, landiolol likely reduces POAF and may reduce LOS. A definitive large RCT is needed to confirm these findings.Study registrationPROSPERO (CRD42021262703); registered 25 July 2021. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research

In reply: Comparing devices for managing the difficult airway
(Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - November 2, 2023 Category: Anesthesiology Source Type: research