Resource use and disease severity of children hospitalized for COVID-19 versus multisystem inflammatory syndrome in children (MIS-C) in Canada
CONCLUSION: While there were more hospitalizations and deaths from acute paediatric COVID-19, MIS-C cases were more severe, requiring more intensive care and vasopressor support. Our findings suggest that both acute COVID-19 and MIS-C should be considered when assessing the overall burden of severe acute respiratory syndrome coronavirus 2 in hospitalized children.PMID:38356877 | PMC:PMC10866613 | DOI:10.14745/ccdr.v49i04a03 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 15, 2024 Category: Infectious Diseases Authors: Daniel Farrar Charlotte Moore Hepburn Olivier Drouin Tala El Tal Marie-Paule Morin Roberta Berard Melanie King Melanie Laffin Thibodeau Krista Baerg Guillaume Beaudoin-Bussi ères Camille Beaufils Terri-Lyn Bennett Susanne Benseler Kevin Chan Claude Cyr N Source Type: research

Antimicrobial susceptibilities of < em > Neisseria gonorrhoeae < /em > in Canada, 2020
CONCLUSION: Antimicrobial resistance in N. gonorrhoeae remains an important public health concern and continued surveillance is imperative to monitor trends to ensure the recommended therapies will be the most effective.PMID:38298531 | PMC:PMC10829890 | DOI:10.14745/ccdr.v48i1112a10 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 1, 2024 Category: Infectious Diseases Authors: Robyn Thorington Pamela Sawatzky Brigitte Lefebvre Mathew Diggle Linda Hoang Samir Patel Paul Van Caessele Jessica Minion Richard Garceau Myrna Matheson David Haldane Genevieve Gravel Michael R Mulvey Irene Martin Source Type: research

Summary of the National Advisory Committee on Immunization (NACI) Statement-Recommendation on Repeated Seasonal Influenza Vaccination
CONCLUSION: Overall, NACI concluded that there is evidence to recommend annual influenza vaccination, irrespective of whether an individual received the seasonal influenza vaccine in previous seasons. It is neither currently feasible nor warranted to modify existing annual influenza vaccination programs to account for potential negative or positive interference. NACI continues to strongly recommend that seasonal influenza vaccine should be offered annually to everyone six months of age and older who does not have contraindications to the vaccine, irrespective of previous seasons' influenza vaccination status.PMID:38298903 ...
Source: Can Commun Dis Rep - February 1, 2024 Category: Infectious Diseases Authors: Angela Sinilaite Kelsey Young Jesse Papenburg Source Type: research

Summary of the National Advisory Committee on Immunization (NACI) Statement-Recommendations on Fractional Influenza Vaccine Dosing in the Event of a Shortage: Pandemic preparedness
CONCLUSION: NACI recommended that, in the event of a significant population-level shortage of influenza vaccine, a full-dose influenza vaccine should continue to be used, and existing vaccine supply should be prioritized for those considered to be at high risk or capable of transmitting to those at high risk of influenza-related complications or hospitalizations. NACI recommended against the use of fractional doses of influenza vaccine in any population.PMID:38298904 | PMC:PMC10826877 | DOI:10.14745/ccdr.v49i04a01 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 1, 2024 Category: Infectious Diseases Authors: Angela Sinilaite Pamela Doyon-Plourde Kelsey Young Robyn Harrison Source Type: research

Hospital and related resource costs associated with antimicrobial-resistant infections in Canada, 2019
CONCLUSION: Quantifying the outcomes associated with antimicrobial-resistant infections provides valuable information for policymakers and is an essential first step in understanding the total economic impacts of AMR.PMID:38292392 | PMC:PMC10827302 | DOI:10.14745/ccdr.v48i1112a06 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - January 31, 2024 Category: Infectious Diseases Authors: Alan Diener Hui Wang Miriam Nkangu Source Type: research

Prevalence of antimicrobial-resistant organisms in smaller Canadian hospitals: Community, Rural, and Northern Acute Care Point Prevalence (CNAPP-19) Survey, 2019
CONCLUSION: Antimicrobial-resistant organisms remain a serious threat to public health in Canada. The results of this survey warrant further investigation into AROs in smaller Canadian hospitals as a potential reservoir of antimicrobial resistance.PMID:38222826 | PMC:PMC10786237 | DOI:10.14745/ccdr.v48i1112a09 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - January 15, 2024 Category: Infectious Diseases Authors: Shari Thomas Denise Gravel Tropper Braden Knight Donald Sheppard Tanya Lary Jami Mackenzie Greg German Charles Frenette Kathryn Bush Jennifer Ellison Jennifer Happe Jayson Shurgold Source Type: research

National Hepatitis C estimates: Incidence, prevalence, undiagnosed proportion and treatment, Canada, 2019
CONCLUSION: Estimates of HCV incidence and prevalence are key metrics to guide interventions and resource allocation. While our estimates show that HCV incidence has decreased in Canada in recent years and treatment of chronic HCV has continued to increase, ongoing efforts are required to reduce the burden of HCV in Canada.PMID:38222827 | PMC:PMC10786238 | DOI:10.14745/ccdr.v48i1112a07 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - January 15, 2024 Category: Infectious Diseases Authors: Nashira Popovic Anson Williams Simone P érinet Laurence Campeau Qiuying Yang Fan Zhang Ping Yan Jordan Feld Naveed Janjua Marina Klein Mel Krajden William Wong Joseph Cox Source Type: research

Understanding Canadians' knowledge, attitudes and practices related to antimicrobial resistance and antibiotic use: Results from public opinion research
CONCLUSION: High trust in medical professionals presents an important opportunity for knowledge mobilization. Delayed prescriptions may alleviate concerns about the time/money constraints of accessing future care. Consideration should be given to prioritizing access to appropriate diagnostic and other technology for northern and/or remote communities and/or medical settings serving many young children to alleviate concerns of needing a prescription or of needing to return later.PMID:38205428 | PMC:PMC10779429 | DOI:10.14745/ccdr.v48i1112a08 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - January 11, 2024 Category: Infectious Diseases Authors: Anna-Louise Crago St éphanie Alexandre Kahina Abdesselam Denise Gravel Tropper Michael Hartmann Glenys Smith Tanya Lary Source Type: research

Summary of the National Advisory Committee on Immunization (NACI) Rapid Response: Updated interim guidance on Imvamune in the context of ongoing monkeypox outbreaks
CONCLUSION: The updated NACI recommendations provide additional guidance on the use of Imvamune for the management of the 2022 monkeypox outbreak in Canada and may be considered to maximize vaccine coverage in outbreak settings when supply is limited.PMID:38192609 | PMC:PMC10773661 | DOI:10.14745/ccdr.v48i1112a11 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - January 9, 2024 Category: Infectious Diseases Authors: Nicole Forbes Oliver Baclic Robyn Harrison Nicholas Brousseau Source Type: research

Summary of the National Advisory Committee on Immunization (NACI) Rapid Response: Updated interim guidance on Imvamune in the context of ongoing monkeypox outbreaks
CONCLUSION: The updated NACI recommendations provide additional guidance on the use of Imvamune for the management of the 2022 monkeypox outbreak in Canada and may be considered to maximize vaccine coverage in outbreak settings when supply is limited.PMID:38192609 | PMC:PMC10773661 | DOI:10.14745/ccdr.v48i1112a11 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - January 9, 2024 Category: Infectious Diseases Authors: Nicole Forbes Oliver Baclic Robyn Harrison Nicholas Brousseau Source Type: research

Overview of Canada's Antimicrobial Resistance Network (AMRNet): A data-driven One Health approach to antimicrobial resistance surveillance
This article describes the AMRNet surveillance system, including program objectives, system structure and the data collected. The integration of human and animal data in AMRNet will inform One Health responses to AMR issues. The capacity to collect and to disseminate data to stakeholders in real time is a critical step to addressing emerging AMR issues in Canada.PMID:38173468 | PMC:PMC10760988 | DOI:10.14745/ccdr.v48i1112a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - January 4, 2024 Category: Infectious Diseases Authors: Wallis Rudnick Shamir N Mukhi Richard J Reid-Smith Greg J German Anil Nichani Michael R Mulvey Canadian Public Health Laboratory Network Antimicrobial Resistance Working Group Canadian Animal Health Laboratorians Network Antimicrobial Susceptibility Testi Source Type: research

Short-course antibiotic therapy: The next frontier in antimicrobial stewardship
This article will review the origins and evolution of our approach regarding antimicrobial prescription duration, the evidence for the use of short-course therapy for selected infections, barriers to the uptake of this practice and potential approaches that can be taken to reduce inappropriately long antibiotic use.PMID:38173469 | PMC:PMC10763651 | DOI:10.14745/ccdr.v48i1112a01 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - January 4, 2024 Category: Infectious Diseases Authors: Donald Sheppard Source Type: research

The Canadian Nosocomial Infection Surveillance Program: Keeping an eye on antimicrobial resistance in Canadian hospitals since 1995
This article aims to increase awareness of CNISP hospital-based surveillance activities. Since its inception in 1995, the scope of CNISP has expanded to include community-associated infections, outpatient Clostridioides difficile infections, viral respiratory infections such as coronavirus disease 2019, and emerging pathogens such as Candida auris. This change in scope, along with expansion to include rural, northern and community hospitals, has improved the generalizability of CNISP surveillance data. To generate actionable surveillance data, CNISP integrates demographic and clinical data abstracted from patient charts wi...
Source: Can Commun Dis Rep - January 4, 2024 Category: Infectious Diseases Source Type: research

Antibiotic prescribing and antimicrobial stewardship in long-term care facilities: Past interventions and implementation challenges
CONCLUSION: This article highlights the need for more well-designed studies that explore innovative and multifaceted solutions to AMS in LTCFs.PMID:38173694 | PMC:PMC10760990 | DOI:10.14745/ccdr.v48i1112a04 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - January 4, 2024 Category: Infectious Diseases Authors: Niyati Vyas Tyler Good Jorida Cila Mark Morrissey Denise Gravel Tropper Source Type: research

Moving the needle on dental antibiotic overuse in Canada post COVID-19
Can Commun Dis Rep. 2022 Nov 3;48(11-12):502-505. doi: 10.14745/ccdr.v48i1112a02. eCollection 2022 Nov 3.ABSTRACTAntimicrobial resistance due to over-prescribing in health care, including in dentistry, has been acknowledged as one of the top ten threats to global health by the World Health Organization. Dentistry is responsible for approximately 10% of antibiotics prescribed worldwide and research has shown up to 80% of antibiotics prescribed by dentists may be unnecessary. During the early months of the coronavirus disease 2019 pandemic, when dental offices handled only dental emergencies, it is probable that antibiotics ...
Source: Can Commun Dis Rep - January 4, 2024 Category: Infectious Diseases Authors: Susan Sutherland Karen Born Sonica Singhal Source Type: research