Healthcare-associated infections and antimicrobial resistance in Canadian acute care hospitals, 2017-2021
CONCLUSION: From 2017 to 2021, the incidence of MRSA and VRE BSIs, and CPE infections increased in Canadian acute care hospitals participating in a national sentinel network (CNISP) while CDI decreased. Few C. auris isolates were identified from 2012 to 2021. Reporting standardized surveillance data and the consistent application of infection prevention and control practises in acute care hospitals are critical to help decrease the burden of HAIs and AMR in Canada.PMID:38425696 | PMC:PMC10903608 | DOI:10.14745/ccdr.v49i05a09 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 1, 2024 Category: Infectious Diseases Authors: Canadian Nosocomial Infection Surveillance Program1* Source Type: research

Device and surgical procedure-related infections in Canadian acute care hospitals, 2017-2021
CONCLUSION: Epidemiological and microbiological trends among select device and surgical procedure-related HAIs are essential for benchmarking infection rates nationally and internationally, identifying any changes in infection rates or antimicrobial resistance patterns and helping inform hospital infection prevention and control and antimicrobial stewardship policies and programs.PMID:38419908 | PMC:PMC10901258 | DOI:10.14745/ccdr.v49i05a08 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 29, 2024 Category: Infectious Diseases Authors: Canadian Nosocomial Infection Surveillance Program1* Source Type: research

Relative pandemic severity in Canada and four peer nations during the SARS-CoV-2 pandemic
CONCLUSION: Canada outperformed several peer countries that aimed for mitigation rather than elimination of SARS-CoV-2 in the first two years of the pandemic, with substantial numbers of lives saved and economic costs averted. However, a comparison with Australia demonstrated that an elimination focus would have saved Canada tens of thousands of lives as well as substantial economic costs.PMID:38419909 | PMC:PMC10901147 | DOI:10.14745/ccdr.v49i05a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 29, 2024 Category: Infectious Diseases Authors: Amy Peng Alison Simmons Afia Amoako Ashleigh Tuite David Fisman Source Type: research

Device and surgical procedure-related infections in Canadian acute care hospitals, 2017-2021
CONCLUSION: Epidemiological and microbiological trends among select device and surgical procedure-related HAIs are essential for benchmarking infection rates nationally and internationally, identifying any changes in infection rates or antimicrobial resistance patterns and helping inform hospital infection prevention and control and antimicrobial stewardship policies and programs.PMID:38419908 | PMC:PMC10901258 | DOI:10.14745/ccdr.v49i05a08 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 29, 2024 Category: Infectious Diseases Authors: Canadian Nosocomial Infection Surveillance Program1* Source Type: research

Relative pandemic severity in Canada and four peer nations during the SARS-CoV-2 pandemic
CONCLUSION: Canada outperformed several peer countries that aimed for mitigation rather than elimination of SARS-CoV-2 in the first two years of the pandemic, with substantial numbers of lives saved and economic costs averted. However, a comparison with Australia demonstrated that an elimination focus would have saved Canada tens of thousands of lives as well as substantial economic costs.PMID:38419909 | PMC:PMC10901147 | DOI:10.14745/ccdr.v49i05a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 29, 2024 Category: Infectious Diseases Authors: Amy Peng Alison Simmons Afia Amoako Ashleigh Tuite David Fisman Source Type: research

Real-time quantitative reverse transcription polymerase chain reaction detection of SARS-CoV-2 Delta variant in Canadian wastewater
CONCLUSION: This study demonstrates a novel cost-effective RT-qPCR assay for tracking the spread of the SARS-CoV-2 Delta variant. This rapid assay can be easily integrated into current wastewater surveillance programs to aid in population-level variant tracking.PMID:38414535 | PMC:PMC10898651 | DOI:10.14745/ccdr.v49i05a07 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 28, 2024 Category: Infectious Diseases Authors: Shelley Peterson Jade Daigle Codey Dueck Audra Nagasawa Michael Mulvey Chand S Mangat Source Type: research

COVID-19 farm outbreaks in Ontario, January-December 2020
CONCLUSION: Farm outbreaks were a source of COVID-19 transmission and illness in 2020, particularly in the spring and fall. Outbreaks continued in greenhouse farms despite lower summer community transmission.PMID:38414536 | PMC:PMC10898618 | DOI:10.14745/ccdr.v49i05a06 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 28, 2024 Category: Infectious Diseases Authors: Hetal Patel Ana Ulloa Sarah Buchan Mariana Abdulnoor Jonathan Gubbay Michelle Murti Source Type: research

Real-time quantitative reverse transcription polymerase chain reaction detection of SARS-CoV-2 Delta variant in Canadian wastewater
CONCLUSION: This study demonstrates a novel cost-effective RT-qPCR assay for tracking the spread of the SARS-CoV-2 Delta variant. This rapid assay can be easily integrated into current wastewater surveillance programs to aid in population-level variant tracking.PMID:38414535 | PMC:PMC10898651 | DOI:10.14745/ccdr.v49i05a07 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 28, 2024 Category: Infectious Diseases Authors: Shelley Peterson Jade Daigle Codey Dueck Audra Nagasawa Michael Mulvey Chand S Mangat Source Type: research

COVID-19 farm outbreaks in Ontario, January-December 2020
CONCLUSION: Farm outbreaks were a source of COVID-19 transmission and illness in 2020, particularly in the spring and fall. Outbreaks continued in greenhouse farms despite lower summer community transmission.PMID:38414536 | PMC:PMC10898618 | DOI:10.14745/ccdr.v49i05a06 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 28, 2024 Category: Infectious Diseases Authors: Hetal Patel Ana Ulloa Sarah Buchan Mariana Abdulnoor Jonathan Gubbay Michelle Murti Source Type: research

Comparison of fifteen SARS-CoV-2 nucleic acid amplification test assays used during the Canadian Laboratory Response Network's National SARS-CoV-2 Proficiency Program, May 2020 to June 2021
CONCLUSION: This study confirmed the rapid and successful implementation of a Canadian PT Program and provided comparative analysis of the various emergency use authorized and laboratory developed tests employed for the detection of SARS-CoV-2 and demonstrated an overall 99.3% test concordance nationwide.PMID:38410252 | PMC:PMC10896585 | DOI:10.14745/ccdr.v49i05a03 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 27, 2024 Category: Infectious Diseases Authors: Charlene Ranadheera Kym Antonation Cindi Corbett Source Type: research

Innovative technology and established partnerships-a recipe for rapid adaptability under emerging pandemic conditions
CONCLUSION: In response to a novel public health threat, CNPHI and CPSP were able to implement rapid adaptations and enhancements to existing data collection instruments while fortifying their preparedness to do the same in the future, when needed. With innovative and agile technologies at the ready, this experience helps to emphasize the importance of established collaborative partnerships across public health disciplines as a factor contributing to preparedness and agility to respond to the unforeseen. Canadian Network for Public Health Intelligence's Web Data technology showed agile adaptability and a capacity for compl...
Source: Can Commun Dis Rep - February 27, 2024 Category: Infectious Diseases Authors: Shamir Mukhi Melanie Laffin-Thibodeau Tim Beattie Source Type: research

Coupling wastewater-based epidemiological surveillance and modelling of SARS-COV-2/COVID-19: Practical applications at the Public Health Agency of Canada
This article reviews the framework of the national WBS conducted at the Public Health Agency of Canada to present WBS methods used in Canada to track and monitor SARS-CoV-2. In particular, we focus on five Canadian cities-Vancouver, Edmonton, Toronto, Montréal and Halifax-whose wastewater signals are analyzed by a mathematical model to provide case forecasts and reproduction number estimates. The goal of this work is to share our insights on approaches to implement WBS. Importantly, the national WBS system has implications beyond COVID-19, as a similar framework can be applied to monitor other infectious disease pathogens...
Source: Can Commun Dis Rep - February 26, 2024 Category: Infectious Diseases Authors: Meong Jin Joung Chand S Mangat Edgard M Mejia Audra Nagasawa Anil Nichani Carol Perez-Iratxeta Shelley W Peterson David Champredon Source Type: research

Evolution of nucleic acid amplification testing across Canada as observed through the Canadian Laboratory Response Network's SARS-CoV-2 Proficiency Test Program, May 2020 to June 2021
This article will explore the evolution of CLRN's SARS-CoV-2 Proficiency Test Program and its support of the Canadian pandemic response.PMID:38404705 | PMC:PMC10890811 | DOI:10.14745/ccdr.v49i05a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 26, 2024 Category: Infectious Diseases Authors: Charlene Ranadheera Kym Antonation Cindi Corbett Source Type: research

Coupling wastewater-based epidemiological surveillance and modelling of SARS-COV-2/COVID-19: Practical applications at the Public Health Agency of Canada
This article reviews the framework of the national WBS conducted at the Public Health Agency of Canada to present WBS methods used in Canada to track and monitor SARS-CoV-2. In particular, we focus on five Canadian cities-Vancouver, Edmonton, Toronto, Montréal and Halifax-whose wastewater signals are analyzed by a mathematical model to provide case forecasts and reproduction number estimates. The goal of this work is to share our insights on approaches to implement WBS. Importantly, the national WBS system has implications beyond COVID-19, as a similar framework can be applied to monitor other infectious disease pathogens...
Source: Can Commun Dis Rep - February 26, 2024 Category: Infectious Diseases Authors: Meong Jin Joung Chand S Mangat Edgard M Mejia Audra Nagasawa Anil Nichani Carol Perez-Iratxeta Shelley W Peterson David Champredon Source Type: research

Evolution of nucleic acid amplification testing across Canada as observed through the Canadian Laboratory Response Network's SARS-CoV-2 Proficiency Test Program, May 2020 to June 2021
This article will explore the evolution of CLRN's SARS-CoV-2 Proficiency Test Program and its support of the Canadian pandemic response.PMID:38404705 | PMC:PMC10890811 | DOI:10.14745/ccdr.v49i05a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - February 26, 2024 Category: Infectious Diseases Authors: Charlene Ranadheera Kym Antonation Cindi Corbett Source Type: research