Nirmatrelvir-ritonavir use among adults hospitalized with COVID-19 during the Omicron phase of the COVID-19 pandemic, Canadian Nosocomial Infection Surveillance Program
CONCLUSION: These findings from a large sentinel network of Canadian acute-care hospitals suggest that nirmatrelvir-ritonavir is being used to treat adult COVID-19 patients at admission who are at risk of progression to severe disease or those who acquired COVID-19 in hospital. Additional research on the efficacy and indications for nirmatrelvir-ritonavir use in hospitalized patients is warranted to inform future policies and guidelines.PMID:38455882 | PMC:PMC10917417 | DOI:10.14745/ccdr.v49i78a07 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 8, 2024 Category: Infectious Diseases Authors: Robyn Mitchell Diane Lee Linda Pelude Jeannette Comeau John Conly Chelsey Ellis Jennifer Ellison John Embil Gerald Evans Lynn Johnston Jennie Johnstone Kevin Katz Pamela Kibsey Bonita Lee Marie-Astrid Lefebvre Yves Longtin Allison McGeer Dominik Mertz Jes Source Type: research
Surveillance for < em > Ixodes scapularis < /em > and < em > Ixodes pacificus < /em > ticks and their associated pathogens in Canada, 2020
CONCLUSION: This article provides a snapshot of the distribution of I. scapularis and I. pacificus and their associated human pathogens in Canada in 2020, which can help assess the risk of exposure to tick-borne pathogens in different provinces.PMID:38444700 | PMC:PMC10914093 | DOI:10.14745/ccdr.v49i06a06 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 6, 2024 Category: Infectious Diseases Authors: Christy Wilson Salima Gasmi Annie-Claude Bourgeois Jacqueline Badcock Justin Carr Navdeep Chahil Heather Coatsworth Antonia Dibernardo Priya Goundar Patrick Leighton Min-Kuang Lee Muhammad Morshed Marion Ripoche Jade Savage eTick, Hanan Smadi3, Christa Sm Source Type: research
Older adults and non-response to rabies post-exposure prophylaxis: Challenges and approaches
We present a case of an 87-year-old male with rabies exposure who failed to respond to two series of RPEP with intramuscular rabies vaccination but responded to a third series using intradermal vaccine administration and provide reasoning for subsequent management. This case is brought forward to prompt discussion and research as to the utility of completing serology in older adults receiving RPEP as well as vaccination strategies, including route of administration, in those who do not respond to an initial course of RPEP vaccination.PMID:38444981 | PMC:PMC10914001 | DOI:10.14745/ccdr.v49i06a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 6, 2024 Category: Infectious Diseases Authors: Reed Morrison Cindy Nguyen Monir Taha Robin Sl Taylor Source Type: research
Surveillance for < em > Ixodes scapularis < /em > and < em > Ixodes pacificus < /em > ticks and their associated pathogens in Canada, 2020
CONCLUSION: This article provides a snapshot of the distribution of I. scapularis and I. pacificus and their associated human pathogens in Canada in 2020, which can help assess the risk of exposure to tick-borne pathogens in different provinces.PMID:38444700 | PMC:PMC10914093 | DOI:10.14745/ccdr.v49i06a06 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 6, 2024 Category: Infectious Diseases Authors: Christy Wilson Salima Gasmi Annie-Claude Bourgeois Jacqueline Badcock Justin Carr Navdeep Chahil Heather Coatsworth Antonia Dibernardo Priya Goundar Patrick Leighton Min-Kuang Lee Muhammad Morshed Marion Ripoche Jade Savage eTick, Hanan Smadi3, Christa Sm Source Type: research
Older adults and non-response to rabies post-exposure prophylaxis: Challenges and approaches
We present a case of an 87-year-old male with rabies exposure who failed to respond to two series of RPEP with intramuscular rabies vaccination but responded to a third series using intradermal vaccine administration and provide reasoning for subsequent management. This case is brought forward to prompt discussion and research as to the utility of completing serology in older adults receiving RPEP as well as vaccination strategies, including route of administration, in those who do not respond to an initial course of RPEP vaccination.PMID:38444981 | PMC:PMC10914001 | DOI:10.14745/ccdr.v49i06a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 6, 2024 Category: Infectious Diseases Authors: Reed Morrison Cindy Nguyen Monir Taha Robin Sl Taylor Source Type: research
Surveillance for < em > Ixodes scapularis < /em > and < em > Ixodes pacificus < /em > ticks and their associated pathogens in Canada, 2020
CONCLUSION: This article provides a snapshot of the distribution of I. scapularis and I. pacificus and their associated human pathogens in Canada in 2020, which can help assess the risk of exposure to tick-borne pathogens in different provinces.PMID:38444700 | PMC:PMC10914093 | DOI:10.14745/ccdr.v49i06a06 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 6, 2024 Category: Infectious Diseases Authors: Christy Wilson Salima Gasmi Annie-Claude Bourgeois Jacqueline Badcock Justin Carr Navdeep Chahil Heather Coatsworth Antonia Dibernardo Priya Goundar Patrick Leighton Min-Kuang Lee Muhammad Morshed Marion Ripoche Jade Savage eTick, Hanan Smadi3, Christa Sm Source Type: research
Older adults and non-response to rabies post-exposure prophylaxis: Challenges and approaches
We present a case of an 87-year-old male with rabies exposure who failed to respond to two series of RPEP with intramuscular rabies vaccination but responded to a third series using intradermal vaccine administration and provide reasoning for subsequent management. This case is brought forward to prompt discussion and research as to the utility of completing serology in older adults receiving RPEP as well as vaccination strategies, including route of administration, in those who do not respond to an initial course of RPEP vaccination.PMID:38444981 | PMC:PMC10914001 | DOI:10.14745/ccdr.v49i06a05 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 6, 2024 Category: Infectious Diseases Authors: Reed Morrison Cindy Nguyen Monir Taha Robin Sl Taylor Source Type: research
Quantifying the economic gains associated with COVID-19 vaccination in the Canadian population: A cost-benefit analysis
CONCLUSION: Our model-based economic evaluation provides a retrospective assessment of COVID-19 vaccination during the first 16 months of the program in Canada and suggests that it was welfare-improving, considering the decreased hospitalizations and use of healthcare resources, deaths averted and lower morbidity from conditions such as PCC.PMID:38440772 | PMC:PMC10911688 | DOI:10.14745/ccdr.v49i06a03 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 5, 2024 Category: Infectious Diseases Authors: Ashleigh R Tuite Victoria Ng Raphael Ximenes Alan Diener Ellen Rafferty Nicholas H Ogden Matthew Tunis Source Type: research
Increased PrEP uptake and PrEP-RN coincide with decreased HIV diagnoses in men who have sex with men in Ottawa, Canada
CONCLUSION: Increasing PrEP uptake in Ottawa in 2017 to 2021 coincided with a significant decrease in new HIV diagnoses among men who have sex with men. PrEP uptake in Ottawa, particularly by those most at risk, is likely supported by an integrated approach via PrEP-RN, a nurse-led public health program where individuals diagnosed with syphilis or rectal gonorrhea or chlamydia receive an automatic offer of PrEP. While these findings cannot causally link PrEP-RN or PrEP with this reduction in new HIV diagnoses, these changes in HIV epidemiology in Ottawa occurred exclusively among the group targeted for PrEP. These data hig...
Source: Can Commun Dis Rep - March 5, 2024 Category: Infectious Diseases Authors: Abigail Kroch Patrick O'Byrne Lauren Orser Paul MacPherson Kristen O'Brien Lucia Light Ryu Kang Agatha Nyambi Source Type: research
Acute severe hepatitis of unknown origin in children in Canada
CONCLUSION: There was no apparent increase above the estimated historical baseline levels.PMID:38435453 | PMC:PMC10907059 | DOI:10.14745/ccdr.v49i06a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 4, 2024 Category: Infectious Diseases Authors: Jennifer Macri Vanessa Morton Meghan Hamel Pierre-Luc Tr épanier Marina I Salvadori Acute Hepatitis Investigation Team Source Type: research
Investigation of acute severe hepatitis in children: A review of liver transplant data, Canada, 2021-2022
Can Commun Dis Rep. 2023 Jun 1;49(6):253-255. doi: 10.14745/ccdr.v49i06a01. eCollection 2023 Jun 1.ABSTRACTAn increase in severe acute hepatitis of unknown etiology was first reported in the United Kingdom in April 2022. Following this report, the Public Health Agency of Canada connected with three paediatric liver transplant centres across Canada to determine if an increase in liver transplants was noted. Data demonstrated no observable increase in the number of transplants conducted in 2022. These data in conjunction with a federal, provincial, territorial investigation provided insight into the situation in Canada.PMID:...
Source: Can Commun Dis Rep - March 4, 2024 Category: Infectious Diseases Authors: Vanessa Morton Meghan Hamel Vicky Ng Susan Gilmour Fernando Alvarez Marina I Salvadori Source Type: research
Acute severe hepatitis of unknown origin in children in Canada
CONCLUSION: There was no apparent increase above the estimated historical baseline levels.PMID:38435453 | PMC:PMC10907059 | DOI:10.14745/ccdr.v49i06a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 4, 2024 Category: Infectious Diseases Authors: Jennifer Macri Vanessa Morton Meghan Hamel Pierre-Luc Tr épanier Marina I Salvadori Acute Hepatitis Investigation Team Source Type: research
Investigation of acute severe hepatitis in children: A review of liver transplant data, Canada, 2021-2022
Can Commun Dis Rep. 2023 Jun 1;49(6):253-255. doi: 10.14745/ccdr.v49i06a01. eCollection 2023 Jun 1.ABSTRACTAn increase in severe acute hepatitis of unknown etiology was first reported in the United Kingdom in April 2022. Following this report, the Public Health Agency of Canada connected with three paediatric liver transplant centres across Canada to determine if an increase in liver transplants was noted. Data demonstrated no observable increase in the number of transplants conducted in 2022. These data in conjunction with a federal, provincial, territorial investigation provided insight into the situation in Canada.PMID:...
Source: Can Commun Dis Rep - March 4, 2024 Category: Infectious Diseases Authors: Vanessa Morton Meghan Hamel Vicky Ng Susan Gilmour Fernando Alvarez Marina I Salvadori Source Type: research
Healthcare-associated infections and antimicrobial resistance in Canadian acute care hospitals, 2017-2021
CONCLUSION: From 2017 to 2021, the incidence of MRSA and VRE BSIs, and CPE infections increased in Canadian acute care hospitals participating in a national sentinel network (CNISP) while CDI decreased. Few C. auris isolates were identified from 2012 to 2021. Reporting standardized surveillance data and the consistent application of infection prevention and control practises in acute care hospitals are critical to help decrease the burden of HAIs and AMR in Canada.PMID:38425696 | PMC:PMC10903608 | DOI:10.14745/ccdr.v49i05a09 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 1, 2024 Category: Infectious Diseases Authors: Canadian Nosocomial Infection Surveillance Program1* Source Type: research
Healthcare-associated infections and antimicrobial resistance in Canadian acute care hospitals, 2017-2021
CONCLUSION: From 2017 to 2021, the incidence of MRSA and VRE BSIs, and CPE infections increased in Canadian acute care hospitals participating in a national sentinel network (CNISP) while CDI decreased. Few C. auris isolates were identified from 2012 to 2021. Reporting standardized surveillance data and the consistent application of infection prevention and control practises in acute care hospitals are critical to help decrease the burden of HAIs and AMR in Canada.PMID:38425696 | PMC:PMC10903608 | DOI:10.14745/ccdr.v49i05a09 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 1, 2024 Category: Infectious Diseases Authors: Canadian Nosocomial Infection Surveillance Program1* Source Type: research
