Relationship between lean body mass and isokinetic peak torque of knee extensors and flexors in severely burned children
Severe burns often result in an extensive hypermetabolic response. The resulting loss of muscle strength is exacerbated by high inactivity associated with prolonged hospitalization and mechanical ventilation [1]. Muscle loss has been shown to begin as early as 48h after immobilization and peaks at 2 –3 weeks [2]. This results in decreased quality of life and delayed return to regular social activities [3]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 29, 2018 Category: Cosmetic Surgery Authors: Christian Tapking, Andrew M. Armenta, Daniel Popp, David N. Herndon, Ludwik K. Branski, Jong O. Lee, Oscar E. Suman Source Type: research

The time-course of the inflammatory response to major burn injury and its relation to organ failure and outcome
Major burn injury induces a profound inflammatory response that in severe cases may lead to multiple organ failure and in some cases death [1]. Common clinical predictors of mortality following burn injury are burn extent, age, presence of inhalation injury and sepsis [2], but many other factors may have a large impact on outcome. The injury itself causes immediate and subsequent cell damage or death, inevitably giving rise to inflammatory cascade activation, as well as altered levels of glucagon, catecholamines and endogenous steroids [3 –5]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 28, 2018 Category: Cosmetic Surgery Authors: Maria Bergquist, Johanna H ästbacka, Christian Glaumann, Filip Freden, Fredrik Huss, Miklos Lipcsey Source Type: research

Epidemiology of work-related burn injuries presenting to burn centres in Australia and New Zealand
Injuries arising out of, or during the course of, employment are a major source of human suffering and economic loss. It has been estimated by the International Labour Organisation that globally, 153 workers suffer a work-related injury every 15s [1]. In Australia work-related injuries are estimated to have cost nearly $62 billion during the 2012 –2013 financial year, equal to approximately 4% of the Gross Domestic Product (GDP) over that time [2]. Burn injuries are among the most devastating of work-related injury types. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 28, 2018 Category: Cosmetic Surgery Authors: Judith A. McInnes, Heather Cleland, Lincoln M. Tracy, Anne Darton, Fiona M. Wood, Tracey Perrett, Belinda J. Gabbe Source Type: research

The trend of burn mortality in Iran — A study of fire, heat and hot substance-related fatal injuries from 1990 to 2015
Burn injuries are a universal health problem and an important cause of death with nearly 180,000 deaths each year. The greatest burden is in low- and middle-income countries [1] where more than 95% of all burn deaths occur [2]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 28, 2018 Category: Cosmetic Surgery Authors: Farideh Sadeghian, Sahar Saeedi Moghaddam, Soheil Saadat, Parastoo Niloofar, Nazila Rezaei, Mohammad Hosein Amirzade-Iranaq, Parinaz Mehdipour, Ali Abbaszadeh Kasbi, Zahra Ghodsi, Anita Mansouri, Mahdi Sharif-Alhosseini, Seyed Behzad Jazayeri, Armin Aryan Source Type: research

The effects of pressure intervention on wound healing and scar formation in a Bama minipig model
Hypertrophic scars (HSs) are pathological tissue structures resulting from aberrations in physiological wound healing after injury to the deep dermis resulting from burns, severe trauma or surgical procedures [1,2]. Excessive scarring is usually characterized by over-proliferation of fibroblasts, abnormal synthesis and degradation of extracellular matrix (ECM), disorders in regulatory cytokines and abnormal neovascularization [3 –6]. Hypertrophic scars are generally raised, red, hard whilst in the form of a contracture, cause itching and painful. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 28, 2018 Category: Cosmetic Surgery Authors: Baimei Liu, Yang Liu, Li Wang, Chunsheng Hou, Meiwen An Source Type: research

Early clinical complete blood count changes in severe burn injuries
It has been well established that following a severe burn injury, there is a progressive anemia caused by dilution from resuscitation, blood loss from open wounds, and hemolysis [1]. Additionally, other cells in the plasma such as white blood cells (WBC) and platelets (PLT) can either be abnormally high or low following a severe burn injury as a result of systemic inflammation [2,3]. These changes are well known and impact resource utilization, such as blood product transfusion, and impact clinical and surgical decision-making [4]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 28, 2018 Category: Cosmetic Surgery Authors: Soman Sen, Luke Hsei, Nam Tran, Kathleen Romanowski, Tina Palmieri, David Greenhalgh, Kiho Cho Source Type: research

The effect of oral N-acetylcystein on prevention of extensive tissue destruction in electrical burn injury
Electrical burns occur in 3 –5% of thermal burns patients [1,2], and cause serious injury in 1000–1500 people every year around the world with a mortality rate of 20–30%. Permanent injury and sequelae were seen in 74% of patients who survived [3,4]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 28, 2018 Category: Cosmetic Surgery Authors: I. Saputro, B. Riestiano, L.T. Hoekstra, L. Zarasade Source Type: research

Development and validity of the Burns-Child Adult Medical Procedure Interaction Scale (B-CAMPIS) for young children
Young children are at risk of increased pain-related distress during medical procedures because they have an underdeveloped cognitive capacity and thus difficulty rationalizing procedural pain as necessary, helpful and temporary [1,2]. Research on child pain-related distress during medical procedures has predominantly been conducted on children undergoing oncology [3], perioperative anesthetic induction [4], and immunization procedures [5]. The majority of children who are hospitalized due to injury (e.g. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 28, 2018 Category: Cosmetic Surgery Authors: E.A. Brown, A. De Young, R. Kimble, J. Kenardy Source Type: research

Planned enteral nutrition over-prescription to cover caloric and protein requirements in severely-ill burn patients
Nutrition therapy is one of the main issues in the management of severely burned patients. The hypermetabolic post-burn response leads to increased nutritional requirements. Metabolic debt leads to altered wound healing, immunosuppression and organ dysfunction [1,2]. Nutritional studies in critically ill patients have reported discrepancies between prescribed and received enteral nutrition (EN) [3,4], caused by the frequent interruptions in EN for investigations, surgery or feeding intolerance: the result is negative energy and protein balances. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 28, 2018 Category: Cosmetic Surgery Authors: Coralie Grang é, François Dépret, Haikel Oueslati, Matthieu Legrand, Sabri Soussi Tags: Letter to the Editor Source Type: research

“SIMBurns”: A high-fidelity simulation program in emergency burn management developed through international collaboration
Acute management of a severely burned patient is an infrequent and stressful emergency situation. The proper management of burn patients requires medical knowledge as well as immediate action. The time-sensitive nature of these situations create a stressful environment, which delineates the importance of having a skilled and well-coordinated team. A significant majority of adverse events in health care are often associated with non-technical skills, such as poor leadership, inadequate teamwork, lack of coordination, and ineffective communication [1]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 26, 2018 Category: Cosmetic Surgery Authors: Federica D ’Asta, Joseph Homsi, Idanna Sforzi, David Wilson, Marco de Luca Source Type: research

First aid for children ’s burns in the US and UK: An urgent call to establish and promote international standards
The prevalence of paediatric burns is decreasing in developed countries, yet the sequelae associated with these injuries can be life altering. Physical disability as a consequence of scarring from serious burns impacts appearance, functional status, long-term morbidity, quality of life and employment [1,2]. Psychological sequelae, often unrelated to the severity of the burn, include anxiety, behavioural disorders and post-traumatic stress disorder [3]. Economically, burns carry a significant burden to society. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 25, 2018 Category: Cosmetic Surgery Authors: C. Verity Bennett, Sabine Maguire, Diane Nuttall, Daniel M. Lindberg, Steven Moulton, Lalit Bajaj, Alison M. Kemp, Stephen Mullen Source Type: research

pH of a burn wound
We noted that many of the chemical burns admitted to our Paediatric Burns Centre had undergone and continued to undergo lengthy periods of irrigation in an attempt to restore the skin to a normal pH. This was causing distress to younger patients. However, following the initial irrigation, the pH did not seem to change significantly and were reported as not reaching normal, despite patients being pain free with no ongoing skin changes. This led us to question the effectiveness of monitoring the pH as a marker for adequate irrigation of chemical burns and whether a normal skin pH was an appropriate end point of irrigation. (...
Source: Burns : Journal of the International Society for Burn Injuries - September 24, 2018 Category: Cosmetic Surgery Authors: Helen Richards, Sian Falder Tags: Letter to the Editor Source Type: research

National Burns Awareness Day 2018, but how aware are British medical students?
The 17th of October marks The British Burns Association ’s (BBA) fifth National Burns Awareness Day [1]. This day, which each year gains more momentum, sets out to raise awareness of the reality of burns injuries, to educate the public on how to prevent burns from occurring and to promote good first-aid. In England between April 2016 and March 2017, 12 2,578 people were seen in accident and emergency departments with burns injuries, a figure that does not even consider the volume of individuals presenting to their general practitioner [2]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 24, 2018 Category: Cosmetic Surgery Authors: Alexander J. Baldwin Tags: Letter to the Editor Source Type: research

Variability of pressure at the pressure garment-scar interface in children after burn: A pilot longitudinal cohort study
The application of pressure to the burn scar via pressure garment therapy is a common burn scar management intervention in high income countries [1 –3]. However, pressure garment therapy has an unknown mechanism of action, an unconfirmed ideal pressure ‘dosage’ at the interface of the pressure garment and burn scar and minimal high quality evidence supporting its use [4,5]. It has been postulated that an interface pressure at or above cap illary pressure is required to occlude local capillaries, thus creating hypoxia in the cells leading to cellular changes including collagen breakdown [3,6,7]. (Source: Burns : Journ...
Source: Burns : Journal of the International Society for Burn Injuries - September 22, 2018 Category: Cosmetic Surgery Authors: Jodie Wiseman, Megan Simons, Roy Kimble, Zephanie Tyack Source Type: research

Glucocorticoids suppress fibroblast apoptosis in an in vitro thermal injury model
In a cutaneous burn wound, there are three zones of thermal injury: the central zone of coagulation, the intermediate zone of stasis, and the outer zone of hyperemia [1]. Because the blood flow in the intermediate zone of stasis decreases naturally after thermal injury, removing the central zone of coagulation and performing immediate skin grafting is one way to rescue the zone of stasis [2]. Without treatment, the tissues in the zone of stasis will gradually die. This change is known as burn wound progression or conversion [3]. (Source: Burns : Journal of the International Society for Burn Injuries)
Source: Burns : Journal of the International Society for Burn Injuries - September 22, 2018 Category: Cosmetic Surgery Authors: Yoshitaka Matsuura, Kazuo Noda, Shigehiko Suzuki, Katsuya Kawai Source Type: research