Breast Cancer Research and Treatment This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Primary MALT lymphoma of the breast: pathological and radiological characteristics
ConclusionPrimary MALT breast lymphomas are usually indolent and non-systemic, and local radiotherapy may effectively alleviate local symptoms. Radiological findings show overlap with benign morphological features, which can delay the diagnosis of this unusual etiology. Although further studies involving a larger cohort could help establish the clinical and radiological characteristics of primary breast MALT lymphomas, pathology remains the primary method of diagnosis.Trial registration numberUniversity Health Network Ethics Committee (CAPCR/UHN REB number 19 –5844), retrospectively registered. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - March 1, 2024 Category: Cancer & Oncology Source Type: research

Liver tropism of ER mutant breast cancer is characterized by unique molecular changes and immune infiltration
ConclusionOur data provide a comprehensive characterization of the behaviors and mechanisms ofESR1 mutant liver metastasis, paving the way for the development of personalized therapy to target liver metastasis for patients withESR1 mutant breast cancer. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - March 1, 2024 Category: Cancer & Oncology Source Type: research

Development of a core outcome set for breast cancer-related lymphedema: a Delphi study
ConclusionThe COS developed in this study thoroughly captures the burden of BCRL. Using this COS may reduce selective reporting, inconsistency in clinical use, and variability of reporting across interdisciplinary healthcare fields, which manage or research BCRL. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 29, 2024 Category: Cancer & Oncology Source Type: research

Pro-vegetarian dietary pattern and risk of breast cancer: a case –control study
ConclusionsThe findings revealed that Iranian women who followed PDP had a lower chance of developing BC. Also, we found that a diet high in plant-based foods and low in animal products is beneficial for reducing BC odds, particularly for post-menopausal women. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 28, 2024 Category: Cancer & Oncology Source Type: research

Opportunities for personalised follow-up in breast cancer: the gap between daily practice and recurrence risk
ConclusionsDeviations from the guideline were not in line with the risk of recurrence and revealed a large gap, indicating that it is hard for clinicians to accurately estimate this risk and therefore objective risk predictions could bridge this gap. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 26, 2024 Category: Cancer & Oncology Source Type: research

Time trends in real-world treatment patterns and survival in patients diagnosed with de novo HER2+  metastatic breast cancer: an analysis of the SONABRE registry
ConclusionThe prognosis of patients with de novo HER2  + ABC has improved considerably. Since 2013 one in four patients were alive and free from progression on first-given therapy for at least five years. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 21, 2024 Category: Cancer & Oncology Source Type: research

Preoperative factors that predict pathologic nodal involvement in early-stage HER2+  breast cancer: selecting cT1cN0 patients for treatment with neoadjuvant chemotherapy versus upfront surgery
ConclusionPatients with cT1cN0 breast cancer have a 32.5% likelihood of nodal metastases, with higher incidence with younger age, LVI, multifocality/multicentricity, and abnormal axillary ultrasound. The presence of these factors may identify the patients who would benefit from treatment with neoadjuvant chemotherapy. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 21, 2024 Category: Cancer & Oncology Source Type: research

Breast cancer diagnosed after age 70 years in Israeli BRCA1/BRCA2 pathogenic sequence variant carriers: a single institution experience
ConclusionIn ~10% ofBRCA1/BRCA2 PSV carriers BC is diagnosed by breast imaging after age 70 years. If these results are validated in a larger study, the guidelines for the maximum age for BC surveillance in high risk women should be revisited and set at 75 years. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 21, 2024 Category: Cancer & Oncology Source Type: research

Geographical distance predicts psychiatric treatment retention for Hispanic women with comorbid major depression and breast cancer
ConclusionIdentifying barriers to treatment is important to improve treatment adherence for patients with concurrent diagnoses of breast cancer and MDD, especially for traditionally underserved minorities. Additional support such as affordable tele-medicine, multi-language assistance, financial aid for transportation and child-care, and allocation of more funds to address some identified barriers deserve consideration to improve treatment adherence and outcomes. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 20, 2024 Category: Cancer & Oncology Source Type: research

Searching for the “Holy Grail” of breast cancer recurrence risk: a narrative review of the hunt for a better biomarker and the promise of circulating tumor DNA (ctDNA)
ConclusionThis review suggests that the emerging promise of ctDNA may help resolve a crticical dilemma at the heart of breast cancer care, and improve prognostication, treatment selection, and outcomes for patients with breast cancer. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 15, 2024 Category: Cancer & Oncology Source Type: research

Reassessing treatment strategies for DCIS: analysis of survival and recurrence patterns
(Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 15, 2024 Category: Cancer & Oncology Source Type: research

The impact of germline BRCA pathogenic variants in locally advanced, triple negative breast cancer treated with platinum-based neoadjuvant chemotherapy
ConclusionCompared to wild-type, gBRCA carriers with locally advanced TNBC treated with neoadjuvant chemotherapy containing carboplatin had a higher pCR rate and better outcomes. These results strengthen the contention that gBRCA status should be considered when tailoring treatment decisions in women with locally advanced TNBC. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 12, 2024 Category: Cancer & Oncology Source Type: research

Socio-cultural and financial issues against breast cancer screening behaviour among eligible Indian women: evidence for action
ConclusionA clear impact of socio-cultural and financial factors on breast cancer screening behavior is evident among Indian women. Therefore, apart from the ongoing health system strengthening efforts, our findings call for targeted interventions against prevailing misconceptions and taboos along with economic and social empowerment of women for the holistic success of India ’s cancer screening strategy. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 12, 2024 Category: Cancer & Oncology Source Type: research

Comparison of long-term oncological outcomes after central lumpectomy versus nipple-sparing breast-conserving surgery for centrally located breast cancer: a propensity score-matched study
ConclusionNS-BCS showed more local recurrence than central lumpectomy. When deciding whether to spare the nipple during BCS in CLBC, patients should be sufficiently informed about the risk of IBTR. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 8, 2024 Category: Cancer & Oncology Source Type: research

Real-world treatment patterns and clinical outcomes in patients treated with eribulin after prior phosphoinositide 3-Kinase inhibitor treatment for metastatic breast cancer
ConclusionOur real-world study suggests that eribulin may be a potential treatment option for MBC patients who fail a prior PI3K inhibitor. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - February 4, 2024 Category: Cancer & Oncology Source Type: research