Neuroblastoma with superficial soft tissue mass as the first symptom: case reports with atypical ultrasonic image and literature review
We describe the imaging findings of ten cases of neuroblastoma patients in our hospital with superficial soft tissue mass (SSTM) as the primary symptom. The main ultrasound finding of SSTM was hypoechoic masses or scattered speck-like hyperechoic masses. However, when this type of SSTM is caused by soft tissue metastasis, the location is often atypical, and ultrasound findings are difficult to distinguish from other benign diseases. Therefore, this research should remind clinicians to recognize atypical presentations of this common childhood malignant tumor. Radiologists should also consider the possibility of neuroblastom...
Source: Brazilian Journal of Medical and Biological Research - December 13, 2023 Category: Research Authors: Jiale Hu Bei Xia Xiuli Yuan Haixing Chen Fuxiang Ou Longlong Huang Lei Xu Xia Feng Source Type: research

Rectangular method: a modified technique for sampling the ischemic border zone in a rat model of transient middle cerebral artery occlusion
Braz J Med Biol Res. 2023 Dec 11;56:e13140. doi: 10.1590/1414-431X2023e13140. eCollection 2023.ABSTRACTTo date, there have been three common methods for sampling the cerebral ischemic border zone in a rat model of transient middle cerebral artery occlusion (tMCAO): the "two o'clock method", the "diagonal method", and the "parallel line method". However, these methods have their own advantages and limitations. Here, we propose a modified technique (the "rectangular method") for sampling the ischemic border zone. A rat tMCAO model was prepared under the support of a compact small animal anesthesia machine. Cerebral blood flo...
Source: Brazilian Journal of Medical and Biological Research - December 13, 2023 Category: Research Authors: Sui-Yi Xu Mao-Mei Song Xue Pan Shi-Na Song Qi Zhang Chang-Xin Li Source Type: research

Assessing multiple factors affecting the gut microbiome structure of very preterm infants
This study confirmed that the different feeding types, delivery modes, and use of antibiotics during pregnancy can significantly affect the composition of the gut microbiota of very preterm infants.PMID:38088676 | PMC:PMC10712283 | DOI:10.1590/1414-431X2023e13186 (Source: Brazilian Journal of Medical and Biological Research)
Source: Brazilian Journal of Medical and Biological Research - December 13, 2023 Category: Research Authors: Wenlong Xiu Jiajia Lin Yanhua Hu Heng Tang Shuangchan Wu Changyi Yang Source Type: research

Sialic acid as the potential link between lipid metabolism and inflammation in the pathogenesis of atherosclerosis
Braz J Med Biol Res. 2023 Dec 11;56:e12972. doi: 10.1590/1414-431X2023e12972. eCollection 2023.ABSTRACTIn the modern world, cardiovascular diseases have a special place among the most common causes of death. Naturally, this widespread problem cannot escape the attention of scientists and researchers. One of the main conditions preceding the development of fatal cardiovascular diseases is atherosclerosis. Despite extensive research into its pathogenesis and possible prevention and treatment strategies, many gaps remain in our understanding of this disease. For example, the concept of multiple low-density lipoprotein modific...
Source: Brazilian Journal of Medical and Biological Research - December 13, 2023 Category: Research Authors: A V Poznyak D A Kashirskikh A Y Postnov M A Popov V N Sukhorukov A N Orekhov Source Type: research

Neuroblastoma with superficial soft tissue mass as the first symptom: case reports with atypical ultrasonic image and literature review
We describe the imaging findings of ten cases of neuroblastoma patients in our hospital with superficial soft tissue mass (SSTM) as the primary symptom. The main ultrasound finding of SSTM was hypoechoic masses or scattered speck-like hyperechoic masses. However, when this type of SSTM is caused by soft tissue metastasis, the location is often atypical, and ultrasound findings are difficult to distinguish from other benign diseases. Therefore, this research should remind clinicians to recognize atypical presentations of this common childhood malignant tumor. Radiologists should also consider the possibility of neuroblastom...
Source: Brazilian Journal of Medical and Biological Research - December 13, 2023 Category: Research Authors: Jiale Hu Bei Xia Xiuli Yuan Haixing Chen Fuxiang Ou Longlong Huang Lei Xu Xia Feng Source Type: research