Brazilian Journal of Medical and Biological Research 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Protective effect of sterubin against neurochemical and behavioral impairments in rotenone-induced Parkinson's disease
This study was conducted to evaluate how sterubin affects rotenone-induced Parkinson's disease (PD) in rats. A total of 24 rats were distributed into 4 equal groups: normal saline control and rotenone control were administered saline or rotenone (ROT), respectively, orally; sterubin 10 received ROT + sterubin 10 mg/kg po; and sterubin alone was administered to the test group (10 mg/kg). Rats of the normal saline and sterubin alone groups received sunflower oil injection (sc) daily, 1 h after receiving the treatments cited above, while rats of the other groups received rotenone injection (0.5 mg/kg, sc). The treatment was c...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: M M Alqurashi F A Al-Abbasi M Afzal A M Alghamdi M Zeyadi R A Sheikh S Alshehri S S Imam N Sayyed I Kazmi Source Type: research
Factors associated with non-treatment of hypertension and gender differences at baseline in the ELSA-Brasil cohort
Braz J Med Biol Res. 2024 Feb 9;57:e12937. doi: 10.1590/1414-431X2023e12937. eCollection 2024.ABSTRACTThe treatment of arterial hypertension (AH) contributes to the reduction of morbidity and mortality. Gender differences are likely to play a role, as non-treatment is associated with clinical and sociodemographic aspects. The aim of this study was to investigate the factors associated with non-treatment of AH and gender differences in hypertensive individuals from the ELSA-Brasil cohort. The study was conducted with 5,743 baseline hypertensive cohort participants. AH was considered if there was a previous diagnosis or if s...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: A K M N éri R M F Xavier S M A Matos M C C Almeida R M Ladeira A A Lopes D O C Lino A P P L ázaro R V B M Cairutas J H Silva J únior J M O Lima M C Chaves R P Silva G B Silva J únior Source Type: research
"Penumbra sign" in knee pain: a case of distal femur osteomyelitis
Braz J Med Biol Res. 2024 Feb 9;57:e12976. doi: 10.1590/1414-431X2023e12976. eCollection 2024.ABSTRACT"Penumbra sign" is a characteristic finding in magnetic resonance imaging (MRI) of Brodie's abscess, a rare variant of subacute osteomyelitis. We aimed to discuss the imaging finding penumbra sign that will help in the diagnosis of osteomyelitis and may be useful to clinicians in differential diagnosis. A 26-year-old male patient presented to the emergency department with complaints of pain and limping in the right knee that did not go away. He had a history of arthroscopic debridement and percutaneous fixation surgery due...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: Hakan Koray Tosyali Adem Çakir Source Type: research
Safety of a 90-min duration of intravenous infusion of obinutuzumab in patients with B-cell non-Hodgkin's lymphoma in a tertiary hospital in China: a prospective, open-label, exploratory clinical trial
This study aimed to analyze the safety and applicability of a 90-min duration of infusion (SDI) of obinutuzumab in patients with B-cell non-Hodgkin's lymphoma (NHL) in a tertiary hospital in China. This exploratory clinical trial was performed at Jiangsu Province Hospital. All patients were treated with the standard infusion regimen for the first infusion. If no grade ≥3 infusion-related reactions (IRRs) occurred, the subsequent infusions were given as SDI. The primary endpoint was the incidence of IRR during the standard infusion (3-4 h) and 90-min SDI regimens. This study enrolled 208 patients and all completed cycle 1...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: Shuangshuang Xing Yiqin Pu Xiaoqian Zhao Yan Hu Feiyan Zhang Zejuan Gu Wei Xu Lei Fan Yi Miao Jianyong Li Source Type: research
Protective effect of sterubin against neurochemical and behavioral impairments in rotenone-induced Parkinson's disease
This study was conducted to evaluate how sterubin affects rotenone-induced Parkinson's disease (PD) in rats. A total of 24 rats were distributed into 4 equal groups: normal saline control and rotenone control were administered saline or rotenone (ROT), respectively, orally; sterubin 10 received ROT + sterubin 10 mg/kg po; and sterubin alone was administered to the test group (10 mg/kg). Rats of the normal saline and sterubin alone groups received sunflower oil injection (sc) daily, 1 h after receiving the treatments cited above, while rats of the other groups received rotenone injection (0.5 mg/kg, sc). The treatment was c...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: M M Alqurashi F A Al-Abbasi M Afzal A M Alghamdi M Zeyadi R A Sheikh S Alshehri S S Imam N Sayyed I Kazmi Source Type: research
Factors associated with non-treatment of hypertension and gender differences at baseline in the ELSA-Brasil cohort
Braz J Med Biol Res. 2024 Feb 9;57:e12937. doi: 10.1590/1414-431X2023e12937. eCollection 2024.ABSTRACTThe treatment of arterial hypertension (AH) contributes to the reduction of morbidity and mortality. Gender differences are likely to play a role, as non-treatment is associated with clinical and sociodemographic aspects. The aim of this study was to investigate the factors associated with non-treatment of AH and gender differences in hypertensive individuals from the ELSA-Brasil cohort. The study was conducted with 5,743 baseline hypertensive cohort participants. AH was considered if there was a previous diagnosis or if s...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: A K M N éri R M F Xavier S M A Matos M C C Almeida R M Ladeira A A Lopes D O C Lino A P P L ázaro R V B M Cairutas J H Silva J únior J M O Lima M C Chaves R P Silva G B Silva J únior Source Type: research
"Penumbra sign" in knee pain: a case of distal femur osteomyelitis
Braz J Med Biol Res. 2024 Feb 9;57:e12976. doi: 10.1590/1414-431X2023e12976. eCollection 2024.ABSTRACT"Penumbra sign" is a characteristic finding in magnetic resonance imaging (MRI) of Brodie's abscess, a rare variant of subacute osteomyelitis. We aimed to discuss the imaging finding penumbra sign that will help in the diagnosis of osteomyelitis and may be useful to clinicians in differential diagnosis. A 26-year-old male patient presented to the emergency department with complaints of pain and limping in the right knee that did not go away. He had a history of arthroscopic debridement and percutaneous fixation surgery due...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: Hakan Koray Tosyali Adem Çakir Source Type: research
Safety of a 90-min duration of intravenous infusion of obinutuzumab in patients with B-cell non-Hodgkin's lymphoma in a tertiary hospital in China: a prospective, open-label, exploratory clinical trial
This study aimed to analyze the safety and applicability of a 90-min duration of infusion (SDI) of obinutuzumab in patients with B-cell non-Hodgkin's lymphoma (NHL) in a tertiary hospital in China. This exploratory clinical trial was performed at Jiangsu Province Hospital. All patients were treated with the standard infusion regimen for the first infusion. If no grade ≥3 infusion-related reactions (IRRs) occurred, the subsequent infusions were given as SDI. The primary endpoint was the incidence of IRR during the standard infusion (3-4 h) and 90-min SDI regimens. This study enrolled 208 patients and all completed cycle 1...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: Shuangshuang Xing Yiqin Pu Xiaoqian Zhao Yan Hu Feiyan Zhang Zejuan Gu Wei Xu Lei Fan Yi Miao Jianyong Li Source Type: research
Protective effect of sterubin against neurochemical and behavioral impairments in rotenone-induced Parkinson's disease
This study was conducted to evaluate how sterubin affects rotenone-induced Parkinson's disease (PD) in rats. A total of 24 rats were distributed into 4 equal groups: normal saline control and rotenone control were administered saline or rotenone (ROT), respectively, orally; sterubin 10 received ROT + sterubin 10 mg/kg po; and sterubin alone was administered to the test group (10 mg/kg). Rats of the normal saline and sterubin alone groups received sunflower oil injection (sc) daily, 1 h after receiving the treatments cited above, while rats of the other groups received rotenone injection (0.5 mg/kg, sc). The treatment was c...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: M M Alqurashi F A Al-Abbasi M Afzal A M Alghamdi M Zeyadi R A Sheikh S Alshehri S S Imam N Sayyed I Kazmi Source Type: research
Factors associated with non-treatment of hypertension and gender differences at baseline in the ELSA-Brasil cohort
Braz J Med Biol Res. 2024 Feb 9;57:e12937. doi: 10.1590/1414-431X2023e12937. eCollection 2024.ABSTRACTThe treatment of arterial hypertension (AH) contributes to the reduction of morbidity and mortality. Gender differences are likely to play a role, as non-treatment is associated with clinical and sociodemographic aspects. The aim of this study was to investigate the factors associated with non-treatment of AH and gender differences in hypertensive individuals from the ELSA-Brasil cohort. The study was conducted with 5,743 baseline hypertensive cohort participants. AH was considered if there was a previous diagnosis or if s...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: A K M N éri R M F Xavier S M A Matos M C C Almeida R M Ladeira A A Lopes D O C Lino A P P L ázaro R V B M Cairutas J H Silva J únior J M O Lima M C Chaves R P Silva G B Silva J únior Source Type: research
"Penumbra sign" in knee pain: a case of distal femur osteomyelitis
Braz J Med Biol Res. 2024 Feb 9;57:e12976. doi: 10.1590/1414-431X2023e12976. eCollection 2024.ABSTRACT"Penumbra sign" is a characteristic finding in magnetic resonance imaging (MRI) of Brodie's abscess, a rare variant of subacute osteomyelitis. We aimed to discuss the imaging finding penumbra sign that will help in the diagnosis of osteomyelitis and may be useful to clinicians in differential diagnosis. A 26-year-old male patient presented to the emergency department with complaints of pain and limping in the right knee that did not go away. He had a history of arthroscopic debridement and percutaneous fixation surgery due...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: Hakan Koray Tosyali Adem Çakir Source Type: research
Safety of a 90-min duration of intravenous infusion of obinutuzumab in patients with B-cell non-Hodgkin's lymphoma in a tertiary hospital in China: a prospective, open-label, exploratory clinical trial
This study aimed to analyze the safety and applicability of a 90-min duration of infusion (SDI) of obinutuzumab in patients with B-cell non-Hodgkin's lymphoma (NHL) in a tertiary hospital in China. This exploratory clinical trial was performed at Jiangsu Province Hospital. All patients were treated with the standard infusion regimen for the first infusion. If no grade ≥3 infusion-related reactions (IRRs) occurred, the subsequent infusions were given as SDI. The primary endpoint was the incidence of IRR during the standard infusion (3-4 h) and 90-min SDI regimens. This study enrolled 208 patients and all completed cycle 1...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: Shuangshuang Xing Yiqin Pu Xiaoqian Zhao Yan Hu Feiyan Zhang Zejuan Gu Wei Xu Lei Fan Yi Miao Jianyong Li Source Type: research
Protective effect of sterubin against neurochemical and behavioral impairments in rotenone-induced Parkinson's disease
This study was conducted to evaluate how sterubin affects rotenone-induced Parkinson's disease (PD) in rats. A total of 24 rats were distributed into 4 equal groups: normal saline control and rotenone control were administered saline or rotenone (ROT), respectively, orally; sterubin 10 received ROT + sterubin 10 mg/kg po; and sterubin alone was administered to the test group (10 mg/kg). Rats of the normal saline and sterubin alone groups received sunflower oil injection (sc) daily, 1 h after receiving the treatments cited above, while rats of the other groups received rotenone injection (0.5 mg/kg, sc). The treatment was c...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: M M Alqurashi F A Al-Abbasi M Afzal A M Alghamdi M Zeyadi R A Sheikh S Alshehri S S Imam N Sayyed I Kazmi Source Type: research
Factors associated with non-treatment of hypertension and gender differences at baseline in the ELSA-Brasil cohort
Braz J Med Biol Res. 2024 Feb 9;57:e12937. doi: 10.1590/1414-431X2023e12937. eCollection 2024.ABSTRACTThe treatment of arterial hypertension (AH) contributes to the reduction of morbidity and mortality. Gender differences are likely to play a role, as non-treatment is associated with clinical and sociodemographic aspects. The aim of this study was to investigate the factors associated with non-treatment of AH and gender differences in hypertensive individuals from the ELSA-Brasil cohort. The study was conducted with 5,743 baseline hypertensive cohort participants. AH was considered if there was a previous diagnosis or if s...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: A K M N éri R M F Xavier S M A Matos M C C Almeida R M Ladeira A A Lopes D O C Lino A P P L ázaro R V B M Cairutas J H Silva J únior J M O Lima M C Chaves R P Silva G B Silva J únior Source Type: research
"Penumbra sign" in knee pain: a case of distal femur osteomyelitis
Braz J Med Biol Res. 2024 Feb 9;57:e12976. doi: 10.1590/1414-431X2023e12976. eCollection 2024.ABSTRACT"Penumbra sign" is a characteristic finding in magnetic resonance imaging (MRI) of Brodie's abscess, a rare variant of subacute osteomyelitis. We aimed to discuss the imaging finding penumbra sign that will help in the diagnosis of osteomyelitis and may be useful to clinicians in differential diagnosis. A 26-year-old male patient presented to the emergency department with complaints of pain and limping in the right knee that did not go away. He had a history of arthroscopic debridement and percutaneous fixation surgery due...
Source: Brazilian Journal of Medical and Biological Research - February 15, 2024 Category: Research Authors: Hakan Koray Tosyali Adem Çakir Source Type: research
