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Systemic analysis of the expression and prognostic significance of USP31 in endometrial cancer
In this study, we tried to investigate the expression of USP31 in EC and its possible involvement in biological signaling pathways and define its predictive value for the prognosis. Data from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) databases confirmed the difference in USP31expression between EC and normal endometrium. Specimens and clinical data of 259 patients with EC who underwent primary surgery at the First Affiliated Hospital of Chongqing Medical University were collected. And the independent predictive value of USP31 for the prognosis of EC patients was determined by univariate and multi...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Yuzhen Huang Peng Jiang Yuting Chen Jinyu Wang Rui Yuan Source Type: research

C5aR1 shapes a non-inflammatory tumor microenvironment and mediates immune evasion in gastric cancer
In this study, the expression of C5aR1 in GC and normal gastric mucosa tissues was compared using data retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, and the results were validated by in vitro qRT-PCR and immunohistochemical analyses. The relationship between C5aR1 expression and the overall survival of patients with GC was analyzed using the Kaplan-Meier method. Subsequently, enrichment analysis was performed, and the signaling pathways were screened. C5aR1 expression was also correlated with genes related to the immune checkpoint and immune cell infiltration. The results re...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Honghong Shen Xianhua Gu Xinwei Li Zheng Xiang Rong Zhang Fan Shi Mingyue Tang Huiyuan Li Guangzheng Zhu Fang Su Zishu Wang Source Type: research

Systemic analysis of the expression and prognostic significance of USP31 in endometrial cancer
In this study, we tried to investigate the expression of USP31 in EC and its possible involvement in biological signaling pathways and define its predictive value for the prognosis. Data from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) databases confirmed the difference in USP31expression between EC and normal endometrium. Specimens and clinical data of 259 patients with EC who underwent primary surgery at the First Affiliated Hospital of Chongqing Medical University were collected. And the independent predictive value of USP31 for the prognosis of EC patients was determined by univariate and multi...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Yuzhen Huang Peng Jiang Yuting Chen Jinyu Wang Rui Yuan Source Type: research

C5aR1 shapes a non-inflammatory tumor microenvironment and mediates immune evasion in gastric cancer
In this study, the expression of C5aR1 in GC and normal gastric mucosa tissues was compared using data retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, and the results were validated by in vitro qRT-PCR and immunohistochemical analyses. The relationship between C5aR1 expression and the overall survival of patients with GC was analyzed using the Kaplan-Meier method. Subsequently, enrichment analysis was performed, and the signaling pathways were screened. C5aR1 expression was also correlated with genes related to the immune checkpoint and immune cell infiltration. The results re...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Honghong Shen Xianhua Gu Xinwei Li Zheng Xiang Rong Zhang Fan Shi Mingyue Tang Huiyuan Li Guangzheng Zhu Fang Su Zishu Wang Source Type: research

Systemic analysis of the expression and prognostic significance of USP31 in endometrial cancer
In this study, we tried to investigate the expression of USP31 in EC and its possible involvement in biological signaling pathways and define its predictive value for the prognosis. Data from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) databases confirmed the difference in USP31expression between EC and normal endometrium. Specimens and clinical data of 259 patients with EC who underwent primary surgery at the First Affiliated Hospital of Chongqing Medical University were collected. And the independent predictive value of USP31 for the prognosis of EC patients was determined by univariate and multi...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Yuzhen Huang Peng Jiang Yuting Chen Jinyu Wang Rui Yuan Source Type: research

C5aR1 shapes a non-inflammatory tumor microenvironment and mediates immune evasion in gastric cancer
In this study, the expression of C5aR1 in GC and normal gastric mucosa tissues was compared using data retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, and the results were validated by in vitro qRT-PCR and immunohistochemical analyses. The relationship between C5aR1 expression and the overall survival of patients with GC was analyzed using the Kaplan-Meier method. Subsequently, enrichment analysis was performed, and the signaling pathways were screened. C5aR1 expression was also correlated with genes related to the immune checkpoint and immune cell infiltration. The results re...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Honghong Shen Xianhua Gu Xinwei Li Zheng Xiang Rong Zhang Fan Shi Mingyue Tang Huiyuan Li Guangzheng Zhu Fang Su Zishu Wang Source Type: research

Systemic analysis of the expression and prognostic significance of USP31 in endometrial cancer
In this study, we tried to investigate the expression of USP31 in EC and its possible involvement in biological signaling pathways and define its predictive value for the prognosis. Data from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) databases confirmed the difference in USP31expression between EC and normal endometrium. Specimens and clinical data of 259 patients with EC who underwent primary surgery at the First Affiliated Hospital of Chongqing Medical University were collected. And the independent predictive value of USP31 for the prognosis of EC patients was determined by univariate and multi...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Yuzhen Huang Peng Jiang Yuting Chen Jinyu Wang Rui Yuan Source Type: research

C5aR1 shapes a non-inflammatory tumor microenvironment and mediates immune evasion in gastric cancer
In this study, the expression of C5aR1 in GC and normal gastric mucosa tissues was compared using data retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, and the results were validated by in vitro qRT-PCR and immunohistochemical analyses. The relationship between C5aR1 expression and the overall survival of patients with GC was analyzed using the Kaplan-Meier method. Subsequently, enrichment analysis was performed, and the signaling pathways were screened. C5aR1 expression was also correlated with genes related to the immune checkpoint and immune cell infiltration. The results re...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Honghong Shen Xianhua Gu Xinwei Li Zheng Xiang Rong Zhang Fan Shi Mingyue Tang Huiyuan Li Guangzheng Zhu Fang Su Zishu Wang Source Type: research

Systemic analysis of the expression and prognostic significance of USP31 in endometrial cancer
In this study, we tried to investigate the expression of USP31 in EC and its possible involvement in biological signaling pathways and define its predictive value for the prognosis. Data from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) databases confirmed the difference in USP31expression between EC and normal endometrium. Specimens and clinical data of 259 patients with EC who underwent primary surgery at the First Affiliated Hospital of Chongqing Medical University were collected. And the independent predictive value of USP31 for the prognosis of EC patients was determined by univariate and multi...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Yuzhen Huang Peng Jiang Yuting Chen Jinyu Wang Rui Yuan Source Type: research

C5aR1 shapes a non-inflammatory tumor microenvironment and mediates immune evasion in gastric cancer
In this study, the expression of C5aR1 in GC and normal gastric mucosa tissues was compared using data retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, and the results were validated by in vitro qRT-PCR and immunohistochemical analyses. The relationship between C5aR1 expression and the overall survival of patients with GC was analyzed using the Kaplan-Meier method. Subsequently, enrichment analysis was performed, and the signaling pathways were screened. C5aR1 expression was also correlated with genes related to the immune checkpoint and immune cell infiltration. The results re...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Honghong Shen Xianhua Gu Xinwei Li Zheng Xiang Rong Zhang Fan Shi Mingyue Tang Huiyuan Li Guangzheng Zhu Fang Su Zishu Wang Source Type: research

Systemic analysis of the expression and prognostic significance of USP31 in endometrial cancer
In this study, we tried to investigate the expression of USP31 in EC and its possible involvement in biological signaling pathways and define its predictive value for the prognosis. Data from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) databases confirmed the difference in USP31expression between EC and normal endometrium. Specimens and clinical data of 259 patients with EC who underwent primary surgery at the First Affiliated Hospital of Chongqing Medical University were collected. And the independent predictive value of USP31 for the prognosis of EC patients was determined by univariate and multi...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Yuzhen Huang Peng Jiang Yuting Chen Jinyu Wang Rui Yuan Source Type: research

C5aR1 shapes a non-inflammatory tumor microenvironment and mediates immune evasion in gastric cancer
In this study, the expression of C5aR1 in GC and normal gastric mucosa tissues was compared using data retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, and the results were validated by in vitro qRT-PCR and immunohistochemical analyses. The relationship between C5aR1 expression and the overall survival of patients with GC was analyzed using the Kaplan-Meier method. Subsequently, enrichment analysis was performed, and the signaling pathways were screened. C5aR1 expression was also correlated with genes related to the immune checkpoint and immune cell infiltration. The results re...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Honghong Shen Xianhua Gu Xinwei Li Zheng Xiang Rong Zhang Fan Shi Mingyue Tang Huiyuan Li Guangzheng Zhu Fang Su Zishu Wang Source Type: research

Systemic analysis of the expression and prognostic significance of USP31 in endometrial cancer
In this study, we tried to investigate the expression of USP31 in EC and its possible involvement in biological signaling pathways and define its predictive value for the prognosis. Data from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) databases confirmed the difference in USP31expression between EC and normal endometrium. Specimens and clinical data of 259 patients with EC who underwent primary surgery at the First Affiliated Hospital of Chongqing Medical University were collected. And the independent predictive value of USP31 for the prognosis of EC patients was determined by univariate and multi...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Yuzhen Huang Peng Jiang Yuting Chen Jinyu Wang Rui Yuan Source Type: research

C5aR1 shapes a non-inflammatory tumor microenvironment and mediates immune evasion in gastric cancer
In this study, the expression of C5aR1 in GC and normal gastric mucosa tissues was compared using data retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases, and the results were validated by in vitro qRT-PCR and immunohistochemical analyses. The relationship between C5aR1 expression and the overall survival of patients with GC was analyzed using the Kaplan-Meier method. Subsequently, enrichment analysis was performed, and the signaling pathways were screened. C5aR1 expression was also correlated with genes related to the immune checkpoint and immune cell infiltration. The results re...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Honghong Shen Xianhua Gu Xinwei Li Zheng Xiang Rong Zhang Fan Shi Mingyue Tang Huiyuan Li Guangzheng Zhu Fang Su Zishu Wang Source Type: research

Systemic analysis of the expression and prognostic significance of USP31 in endometrial cancer
In this study, we tried to investigate the expression of USP31 in EC and its possible involvement in biological signaling pathways and define its predictive value for the prognosis. Data from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) databases confirmed the difference in USP31expression between EC and normal endometrium. Specimens and clinical data of 259 patients with EC who underwent primary surgery at the First Affiliated Hospital of Chongqing Medical University were collected. And the independent predictive value of USP31 for the prognosis of EC patients was determined by univariate and multi...
Source: Bosnian Journal of Basic Medical Sciences - December 12, 2022 Category: General Medicine Authors: Yuzhen Huang Peng Jiang Yuting Chen Jinyu Wang Rui Yuan Source Type: research