Comparison of peak inspiratory flow rate via the Breezhaler ®, Ellipta® and HandiHaler® dry powder inhalers in patients with moderate to very severe COPD: a randomized cross-over trial
The chronic and progressive nature of chronic obstructive pulmonary disease (COPD) requires self-administration of inhaled medication. Dry powder inhalers (DPIs) are increasingly being used for inhalation ther... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - June 14, 2018 Category: Respiratory Medicine Authors: Pablo Altman, Luis Wehbe, Juergen Dederichs, Tadhg Guerin, Brian Ament, Miguel Cardenas Moronta, Andrea Valeria Pino and Pankaj Goyal Tags: Research article Source Type: research

Acute effects of combined exercise and oscillatory positive expiratory pressure therapy on sputum properties and lung diffusing capacity in cystic fibrosis: a randomized, controlled, crossover trial
Regular airway clearance by chest physiotherapy and/or exercise is critical to lung health in cystic fibrosis (CF). Combination of cycling exercise and chest physiotherapy using the Flutter ® device on sputum p... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - June 14, 2018 Category: Respiratory Medicine Authors: Thomas Radtke, Lukas B öni, Peter Bohnacker, Marion Maggi-Beba, Peter Fischer, Susi Kriemler, Christian Benden and Holger Dressel Tags: Research article Source Type: research

Physical activity and sedentary time are related to clinically relevant health outcomes among adults with obstructive lung disease
The purpose of the current study was to determine the association between sedentary time and physical activity with clinically relevant health outcomes among adults with impaired spirometry and those with or w... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - June 7, 2018 Category: Respiratory Medicine Authors: Shilpa Dogra, Joshua Good, Matthew P. Buman, Paul A. Gardiner, Jennifer L. Copeland and Michael K. Stickland Tags: Research article Source Type: research

Pulmonary sequestration in adults: a retrospective review of resected and unresected cases
Pulmonary sequestration (PS) is a form of congenital pulmonary malformation that is generally diagnosed in childhood or adolescence and usually resected when diagnosed. We aim to identify the clinical presenta... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - June 5, 2018 Category: Respiratory Medicine Authors: Mohammad Alsumrain and Jay H. Ryu Tags: Research article Source Type: research

Risk factors for interstitial lung disease: a 9-year Nationwide population-based study
Understanding the risk factors that are associated with the development of interstitial lung disease might have an important role in understanding the pathogenetic mechanism of interstitial lung disease as wel... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - June 4, 2018 Category: Respiratory Medicine Authors: Won-Il Choi, Sonila Dauti, Hyun Jung Kim, Sun Hyo Park, Jae Seok Park and Choong Won Lee Tags: Research article Source Type: research

Global lung function initiative 2012 reference values for spirometry in Asian Americans
Spirometry reference values specifically designed for Asian Americans are currently unavailable. The performance of Global Lung Function Initiative 2012 (GLI-2012) equations on assessing spirometry in Asian Am... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 31, 2018 Category: Respiratory Medicine Authors: Jingzhou Zhang, Xiao Hu, Xinlun Tian and Kai-Feng Xu Tags: Research article Source Type: research

Delayed isolation of smear-positive pulmonary tuberculosis patients in a Japanese acute care hospital
Active pulmonary tuberculosis (TB) is associated with intra-hospital spread of the disease. Expeditious diagnosis and isolation are critical for infection control. However, factors that lead to delayed isolati... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 31, 2018 Category: Respiratory Medicine Authors: Sho Nishiguchi, Shusaku Tomiyama, Izumi Kitagawa and Yasuharu Tokuda Tags: Research article Source Type: research

Effectiveness of a standardized electronic admission order set for acute exacerbation of chronic obstructive pulmonary disease
Variation in hospital management of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may prolong length of stay, increasing the risk of hospital-acquired complications and wor... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 30, 2018 Category: Respiratory Medicine Authors: Sachin R. Pendharkar, Maria B. Ospina, Danielle A. Southern, Naushad Hirani, Jim Graham, Peter Faris, Mohit Bhutani, Richard Leigh, Christopher H. Mody and Michael K. Stickland Tags: Research article Source Type: research

The level of lipopolysaccharide-binding protein is elevated in adult patients with obstructive sleep apnea
This study aimed to test the hypothesis that the concentration of LBP is elevated in adult patients with obstr... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 29, 2018 Category: Respiratory Medicine Authors: Yinfeng Kong, Zhijun Li, Tingyu Tang, Haiyan Wu, Juan Liu, Liang Gu, Tian Zhao and Qingdong Huang Tags: Research article Source Type: research

Mixed pneumonic plague and nosocomial MDR-bacterial infection of lung: a rare case report
Plague is a life-threatening disease caused by the bacterium, Yersinia pestis. Madagascar is the leading country for human plague cases worldwide. Human plague is a serious disease, particularly in its septicaemi... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 29, 2018 Category: Respiratory Medicine Authors: Voahangy Andrianaivoarimanana, Eric Bertherat, Rojo Rajaonarison, Tiana Rakotondramaro, Christophe Rogier and Minoarisoa Rajerison Tags: Case report Source Type: research

Stability of gene expression by primary bronchial epithelial cells over increasing passage number
An increasing number of studies using primary human bronchial epithelial cells (BECs) have reported intrinsic differences in the expression of several genes between cells from asthmatic and non-asthmatic donor... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 29, 2018 Category: Respiratory Medicine Authors: Stephen R. Reeves, Kaitlyn A. Barrow, Maria P. White, Lucille M. Rich, Maryam Naushab and Jason S. Debley Tags: Research article Source Type: research

Effect of altering breathing frequency on maximum voluntary ventilation in healthy adults
Compared to other pulmonary function tests, there is a lack of standardization regarding how a maximum voluntary ventilation (MVV) maneuver is performed. Specifically, little is known about the variation in br... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 24, 2018 Category: Respiratory Medicine Authors: Eric V. Neufeld, Brett A. Dolezal, William Speier and Christopher B. Cooper Tags: Research article Source Type: research

Six underlying health conditions strongly influence mortality based on pneumonia severity in an ageing population of Japan: a prospective cohort study
Mortality prediction of pneumonia by severity scores in patients with multiple underlying health conditions has not fully been investigated. This prospective cohort study is to identify mortality-associated un... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 23, 2018 Category: Respiratory Medicine Authors: Sugihiro Hamaguchi, Motoi Suzuki, Kota Sasaki, Masahiko Abe, Takao Wakabayashi, Eiichiro Sando, Makito Yaegashi, Shimpei Morimoto, Norichika Asoh, Naohisa Hamashige, Masahiro Aoshima, Koya Ariyoshi and Konosuke Morimoto Tags: Research article Source Type: research

NonTuberculous Mycobacteria infection and lung transplantation in cystic fibrosis: a worldwide survey of clinical practice
In people with cystic fibrosis infection with NonTuberculous Mycobacteria is of increasing prevalence. Mycobacterium abscessus complex is of particular concern and has been associated with adverse clinical outcom... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 22, 2018 Category: Respiratory Medicine Authors: Adrien Tissot, Matthew F. Thomas, Paul A. Corris and Malcolm Brodlie Tags: Research article Source Type: research

The first case of multiple pulmonary granulomas with amyloid deposition in a dental technician; a rare manifestation as an occupational lung disease
Occupational lung diseases, such as pneumoconiosis, are one of the health problems of dental workers that have been receiving increasing interest. Pulmonary amyloidosis is a heterogenous group of diseases, and... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 22, 2018 Category: Respiratory Medicine Authors: Taizou Hirano, Tadahisa Numakura, Hiroshi Moriyama, Ryoko Saito, Yutaka Shishikura, Jun Shiihara, Hisatoshi Sugiura and Masakazu Ichinose Tags: Case report Source Type: research

Bronchiectasis: an emerging global epidemic
Bronchiectasis has an increasing profile within respiratory medicine. This chronic and irreversible airways disease is common but suffers from a lack of evidenced based therapy for patients and, a lack of unde... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 22, 2018 Category: Respiratory Medicine Authors: Sanjay H. Chotirmall and James D. Chalmers Tags: Editorial Source Type: research

Outcomes of lung transplantation in adults with bronchiectasis
Lung transplantation is a well-established treatment for end-stage non-cystic fibrosis bronchiectasis (BR), though information regarding outcomes of transplantation remains limited. Our results of lung transpl... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 22, 2018 Category: Respiratory Medicine Authors: Jodie Birch, Syba S. Sunny, Katy L. M. Hester, Gareth Parry, F. Kate Gould, John H. Dark, Stephen C. Clark, Gerard Meachery, James Lordan, Andrew J. Fisher, Paul A. Corris and Anthony De Soyza Tags: Research article Source Type: research

Profiling non-tuberculous mycobacteria in an Asian setting: characteristics and clinical outcomes of hospitalized patients in Singapore
This study investigated the epidemiology, and clinical profile of in... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 22, 2018 Category: Respiratory Medicine Authors: Albert Y. H. Lim, Sanjay H. Chotirmall, Eric T. K. Fok, Akash Verma, Partha P. De, Soon Keng Goh, Ser Hon Puah, Daryl E. L. Goh and John A. Abisheganaden Tags: Research article Source Type: research

Occupational risk factors for idiopathic pulmonary fibrosis in Southern Europe: a case-control study
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial pneumonia of unknown cause associated with the histopathologic and/or radiologic pattern of usual interstitial pneumonia (UI... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 21, 2018 Category: Respiratory Medicine Authors: Giulia Paolocci, Ilenia Folletti, Kjell Tor én, Magnus Ekström, Marco Dell’Omo, Giacomo Muzi and Nicola Murgia Tags: Research article Source Type: research

Relationship between pulmonary function and peripheral vascular function in older Chinese: Guangzhou biobank cohort study-CVD
Findings describing the relationship between pulmonary function and peripheral vascular function have been inconclusive. We explored this relationship in Guangzhou Biobank Cohort Study-Cardiovascular Subcohort... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 21, 2018 Category: Respiratory Medicine Authors: Jing Pan, Lin Xu, Tai Hing Lam, Chao Qiang Jiang, Wei Sen Zhang, Feng Zhu, Ya Li Jin, G. Neil Thomas, Kar Keung Cheng and Peymane Adab Tags: Research article Source Type: research

Radiological pleuroparenchymal fibroelastosis associated to limited cutaneous systemic sclerosis: a case report
Pleuroparenchymal fibroelastosis (PPFE) is a very rare interstitial lung disease (ILD) characterized by progressive fibrotic lesions of the visceral pleura and the sub-pleural parenchyma, affecting predominant... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 18, 2018 Category: Respiratory Medicine Authors: D. Hassoun, S. Dirou, P. P. Arrigoni, C. Durant, M. Hamidou, A. N éel and C. Agard Tags: Case report Source Type: research

Sleep-disordered breathing in patients with newly diagnosed lung cancer
There are currently no data on the prevalence of sleep-disordered breathing (SDB) in patients with newly-diagnosed lung cancer. This might be of interest given that SDB is associated with increased cancer inci... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 16, 2018 Category: Respiratory Medicine Authors: Michael Dreher, Stefan Kr üger, Susanne Schulze-Olden, András Keszei, Jan Hendrik Storre, Holger Woehrle, Michael Arzt and Tobias Müller Tags: Research article Source Type: research

Management of acute respiratory failure in interstitial lung diseases: overview and clinical insights
Interstitial lung diseases (ILDs) are a heterogeneous group of diseases characterized by widespread fibrotic and inflammatory abnormalities of the lung. Respiratory failure is a common complication in advanced... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 15, 2018 Category: Respiratory Medicine Authors: Paola Faverio, Federica De Giacomi, Luca Sardella, Giuseppe Fiorentino, Mauro Carone, Francesco Salerno, Jousel Ora, Paola Rogliani, Giulia Pellegrino, Giuseppe Francesco Sferrazza Papa, Francesco Bini, Bruno Dino Bodini, Grazia Messinesi, Alberto Pesci a Tags: Review Source Type: research

Telerehabilitation versus traditional centre-based pulmonary rehabilitation for people with chronic respiratory disease: protocol for a randomised controlled trial
Pulmonary rehabilitation is an effective therapeutic intervention for people with chronic respiratory disease. However, fewer than 5% of eligible individuals receive pulmonary rehabilitation on an annual basis... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 15, 2018 Category: Respiratory Medicine Authors: Narelle S. Cox, Christine F. McDonald, Jennifer A. Alison, Ajay Mahal, Richard Wootton, Catherine J. Hill, Janet Bondarenko, Heather Macdonald, Paul O ’Halloran, Paolo Zanaboni, Ken Clarke, Deidre Rennick, Kaye Borgelt, Angela T. Burge, Aroub Lahham, Br Tags: Study protocol Source Type: research

Underlying and immediate causes of death in patients with idiopathic pulmonary fibrosis
The most common cause of death of patients with idiopathic pulmonary fibrosis (IPF) has been reported to be the lung disease itself and mortality from IPF appears to be increasing. However, the causes of death... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 11, 2018 Category: Respiratory Medicine Authors: Miia K ärkkäinen, Hanna Nurmi, Hannu-Pekka Kettunen, Tuomas Selander, Minna Purokivi and Riitta Kaarteenaho Tags: Research article Source Type: research

Prevalence of asthma among the adult general population of five Middle Eastern countries: results of the SNAPSHOT program
Asthma is a common chronic respiratory disease leading to morbidity, mortality and impaired quality of life worldwide. Information on asthma prevalence in the Middle East is fragmented and relatively out-dated... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 11, 2018 Category: Respiratory Medicine Authors: Hesham Tarraf, Omur Aydin, Dilsad Mungan, Mohammad Albader, Bassam Mahboub, Adam Doble, Aaicha Lahlou, Luqman Tariq, Fayaz Aziz and Abdelkader El Hasnaoui Tags: Research article Source Type: research

Higher serum 25-hydroxyvitamin D concentrations are associated with active pulmonary tuberculosis in hospitalised HIV infected patients in a low income tropical setting: a cross sectional study
The inherent risk of developing tuberculosis (TB) in HIV- infected individuals is further enhanced by hypovitaminosis D. Interventions that offset HIV-associated immune deterioration potentially arrest disease... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 8, 2018 Category: Respiratory Medicine Authors: Cuthbert Musarurwa, Lynn Sodai Zijenah, Doreen Zvipo Mhandire, Tsitsi Bandason, Kudakwashe Mhandire, Maria Mary Chipiti, Marshall Wesley Munjoma and Witmore Bayayi Mujaji Tags: Research article Source Type: research

Potential effect of household environment on prevalence of tuberculosis in India: evidence from the recent round of a cross-sectional survey
Tuberculosis (TB) has been a major health problem globally since ages, and even today, it is a major cause of morbidity in millions of people each year. In 2015 alone, TB accounted for about 1.4 million deaths... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 3, 2018 Category: Respiratory Medicine Authors: S. K. Singh, Gyan Chandra Kashyap and Parul Puri Tags: Research article Source Type: research

Clinical utility of blood neutrophil-lymphocyte ratio in Japanese COPD patients
Neutrophil-to-lymphocyte ratio (NLR) is a biomarker of inflammation in chronic obstructive pulmonary disease (COPD) patients. But, a meaningful threshold and the longitudinal changes are unknown. We aimed to i... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 2, 2018 Category: Respiratory Medicine Authors: Kaori Sakurai, Shotaro Chubachi, Hidehiro Irie, Akihiro Tsutsumi, Naofumi Kameyama, Takashi Kamatani, Hidefumi Koh, Takeshi Terashima, Hidetoshi Nakamura, Koichiro Asano and Tomoko Betsuyaku Tags: Research article Source Type: research

Delays to treatment initiation is associated with tuberculosis treatment outcomes among patients on directly observed treatment short course in Southwest Ethiopia: a follow-up study
Despite reported long delays to initiate anti-TB treatment and poor outcomes in different parts of Ethiopia and elsewhere, evidences on association between the delay and treatment outcomes are scanty. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 2, 2018 Category: Respiratory Medicine Authors: Abyot Asres, Degu Jerene and Wakgari Deressa Tags: Research article Source Type: research

Anti-fibrotic effects of pirfenidone and rapamycin in primary IPF fibroblasts and human alveolar epithelial cells
Pirfenidone, a pleiotropic anti-fibrotic treatment, has been shown to slow down disease progression of idiopathic pulmonary fibrosis (IPF), a fatal and devastating lung disease. Rapamycin, an inhibitor of fibr... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 27, 2018 Category: Respiratory Medicine Authors: M. Molina-Molina, C. Machahua-Huamani, V. Vicens-Zygmunt, R. Llatj ós, I. Escobar, E. Sala-Llinas, P. Luburich-Hernaiz, J. Dorca and A. Montes-Worboys Tags: Research article Source Type: research

Improved heart hemodynamics after draining large-volume pleural effusion: a prospective cohort study
Pleural effusion (PE) drainage can relieve the symptoms of dyspnea; however, details of the resulting hemodynamic changes remain undefined. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 25, 2018 Category: Respiratory Medicine Authors: Zheng Wang, Qi-Zhe Cai, Cheng-Jun Ban, Duo Chen, Li-Li Xu, Xiao-Juan Wang, Zhen Wang, Yuan Yang, Xiu-Zhang Lv and Huan-Zhong Shi Tags: Research article Source Type: research

Factors associated with asthma control: MOSAR study (Multicenter Observational Study of Asthma in Rabat-Morocco)
The purpose of the study is to describe the profile of patients with asthma and to identify the signifiant risks and the protective factors associated with asthma control. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 24, 2018 Category: Respiratory Medicine Authors: Imane Ghanname, Ahmed Chaker, Abha Cherkani Hassani, Laila Herrak, Serge Arnaul Ebongue, Mustapha Laine, Khalid Rahhali, Abdelhak Zoglat, Aida Maria Benitez Rexach, Samir Ahid and Yahia Cherrah Tags: Research article Source Type: research

Is daily physical activity affected by dynamic hyperinflation in adults with cystic fibrosis?
The aim of this study was to investigate the relationship between dynamic hyperinflation and daily physical activity (DPA) in adults with cystic fibrosis (CF). (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 19, 2018 Category: Respiratory Medicine Authors: Daniela Savi, Marcello Di Paolo, Nicholas J. Simmonds, Chiara Pascucci, Serena Quattrucci and Paolo Palange Tags: Research article Source Type: research

MDA-5 associated rapidly progressive interstitial lung disease with recurrent Pneumothoraces: a case report
Clinically hypomyopathic dermatomyositis is a rare disease that is important to recognize, investigate and treat early as it is associated with poor prognosis. In a proportion of patients, myositis specific an... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 17, 2018 Category: Respiratory Medicine Authors: Safi Alqatari, Peter Riddell, Sinead Harney, Michael Henry and Grainne Murphy Tags: Case report Source Type: research

Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma
Although pre-puberty asthma is more prevalent in males, after puberty through middle-age, asthma is more prevalent in females. The surge of sex hormones with puberty might explain this gender switch. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 10, 2018 Category: Respiratory Medicine Authors: Mark D. DeBoer, Brenda R. Phillips, David T. Mauger, Joe Zein, Serpil C. Erzurum, Anne M. Fitzpatrick, Benjamin M. Gaston, Ross Myers, Kristie R. Ross, James Chmiel, Min Jie Lee, John V. Fahy, Michael Peters, Ngoc P. Ly, Sally E. Wenzel, Merritt L. Fajt & Tags: Research article Source Type: research

Comparative bench study evaluation of different infant interfaces for non-invasive ventilation
To compare, in terms of patient-ventilator interaction and performance, a new nasal mask (Respireo, AirLiquide, FR) with the Endotracheal tube (ET) and a commonly used nasal mask (FPM, Fisher and Paykel, NZ) f... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 7, 2018 Category: Respiratory Medicine Authors: Giorgio Conti, Giorgia Spinazzola, Cesare Gregoretti, Giuliano Ferrone, Andrea Cortegiani, Olimpia Festa, Marco Piastra, Luca Tortorolo and Roberta Costa Tags: Research article Source Type: research

Malignant pleural mesothelioma: diagnostic value of medical thoracoscopy and long-term prognostic analysis
Malignant pleural mesothelioma (MPM) is marked by its difficult diagnosis and poor prognosis. Medical thoracoscopy (MT) is an effective and safe procedure for the diagnosis of exudative pleural effusions and m... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 3, 2018 Category: Respiratory Medicine Authors: Li-Li Xu, Yuan Yang, Zhen Wang, Xiao-Juan Wang, Zhao-Hui Tong and Huan-Zhong Shi Tags: Research article Source Type: research

Aspergillus fumigatus during COPD exacerbation: a pair-matched retrospective study
Recently awareness of the importance of Aspergillus colonization in the airway of patients with chronic obstructive pulmonary disease (COPD) was rising. The aim of this study was to investigate the clinical fe... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 3, 2018 Category: Respiratory Medicine Authors: Xunliang Tong, Anqi Cheng, Hongtao Xu, Jin Jin, Yimeng Yang, Sainan Zhu and Yanming Li Tags: Research article Source Type: research

The association between circulating adiponectin levels, lung function and adiposity in subjects from the general population; data from the Akershus Sleep Apnea Project
Circulating adiponectin (ADPN) levels are inversely associated with disease severity in patients with chronic obstructive pulmonary disease (COPD), while studies assessing the relationship between ADPN and lun... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 2, 2018 Category: Respiratory Medicine Authors: Nina F. Caspersen, Helge R øsjø, Allan Flyvbjerg, Mette Bjerre, Anna Randby, Harald Hrubos-Strøm, Torbjørn Omland and Gunnar Einvik Tags: Research article Source Type: research

A case of allergic bronchopulmonary aspergillosis successfully treated with mepolizumab
Allergic bronchopulmonary aspergillosis (ABPA) is an allergic pulmonary disease comprising a complex hypersensitivity reaction to Aspergillus fumigatus. Clinical features of ABPA are wheezing, mucoid impaction, a... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 27, 2018 Category: Respiratory Medicine Authors: Takeshi Terashima, Taro Shinozaki, Eri Iwami, Takahiro Nakajima and Tatsu Matsuzaki Tags: Case report Source Type: research

Serum (1 →3)-β-D-glucan and galactomannan levels in patients with cystic fibrosis: a retrospective cohort study
Aspergillus fumigatus is frequently encountered in sputum samples of patients with cystic fibrosis (CF), which traditionally has been interpreted as saprophytic airway colonization. However, this mere bystander r... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 27, 2018 Category: Respiratory Medicine Authors: Johannes Tr äger, Volker Otto Melichar, Renate Meyer, Manfred Rauh, Christian Bogdan and Jürgen Held Tags: Research article Source Type: research

IFN Λ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes
Interferon lambdas (IFNLs) have important anti-viral/bacterial and immunomodulatory functions in the respiratory tract. How do IFNLs impact COPD and its exacerbations? (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 21, 2018 Category: Respiratory Medicine Authors: Adrian Egli, Jyotshna Mandal, Desiree M. Schumann, Michael Roth, Brad Thomas, D. Lorne Tyrrell, Francesco Blasi, Kostantinos Kostikas, Wim Boersma, Branislava Milenkovic, Alicia Lacoma, Katharina Rentsch, Gernot G. U. Rohde, Renaud Louis, Joachim G. Aerts Tags: Research article Source Type: research

Pulmonary interstitial emphysema in fatal asthma: case report and histopathological review
Mortality related to asthma has decreased worldwide since the introduction of inhaled corticosteroid therapy in the past decades. However, there are still some asthma fatalities identified mainly in population... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 20, 2018 Category: Respiratory Medicine Authors: Thais Mauad, Felipe B. P. do Nascimento, Marisa Dolhnikoff, Milena C. M. Picka and Paulo H. N. Saldiva Tags: Case report Source Type: research

The relation between air pollution and respiratory deaths in Tehran, Iran- using generalized additive models
Some epidemiological evidence has shown a relation between ambient air pollution and adverse health outcomes. The aim of this study was to investigate the effect of air pollution on mortality from respiratory ... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 20, 2018 Category: Respiratory Medicine Authors: Azizallah Dehghan, Narges Khanjani, Abbas Bahrampour, Gholamreza Goudarzi and Masoud Yunesian Tags: Research article Source Type: research

CC16 levels correlate with cigarette smoke exposure in bronchial epithelial cells and with lung function decline in smokers
Club cell protein-16 (CC16) expression has been associated with smoking-related lung function decline. The study hypothesis was that CC16 expression in both serum and bronchial epithelium is associated with lu... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 16, 2018 Category: Respiratory Medicine Authors: David Chi-Leung Lam, Hoi-Hin Kwok, Wai-Cho Yu, Fanny Wai-San Ko, Cheuk-Yin Tam, Arthur Chun-Wing Lau, Daniel Yee-Tak Fong and Mary Sau-Man Ip Tags: Research article Source Type: research

Clinical and economic impact of a one-year treatment with omalizumab in patients with severe allergic asthma within a drug programme in Poland
Allergic asthma is the most prevalent phenotype of severe asthma where treatment with omalizumab (OMB) has been proven to be particularly beneficial. In Poland, OMB therapy is available and reimbursed within a... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 16, 2018 Category: Respiratory Medicine Authors: Karina Jahnz-R óżyk, Joanna Lis, Marta Warchoł and Aleksandra Kucharczyk Tags: Research article Source Type: research

Interventional bronchoscopy in malignant central airway obstruction by extra-pulmonary malignancy
Interventional bronchoscopy is considered an effective treatment option for malignant central airway obstruction (MCAO). However, there are few reports of interventional bronchoscopy in patients with MCAOs due... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 13, 2018 Category: Respiratory Medicine Authors: Beomsu Shin, Boksoon Chang, Hojoong Kim and Byeong-Ho Jeong Tags: Research article Source Type: research

Prevalence of pre-transplant anti-HLA antibodies and their impact on outcomes in lung transplant recipients
Previous studies have suggested that antibodies against human leukocyte antigen (HLA) are associated with worse outcomes in lung transplantation. However, little is known about the factors associated with outc... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 12, 2018 Category: Respiratory Medicine Authors: Ji Eun Park, Chi Young Kim, Moo Suk Park, Joo Han Song, Young Sam Kim, Jin Gu Lee, Hyo Chae Paik and Song Yee Kim Tags: Research article Source Type: research

Elevated α-defensin levels in plasma and bronchoalveolar lavage fluid from patients with myositis-associated interstitial lung disease
Interstitial lung disease (ILD) is a prognostic indicator of poor outcome in myositis. Although the pathogenesis of myositis-associated ILD is not well understood, neutrophils are thought to play a pivotal rol... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - March 12, 2018 Category: Respiratory Medicine Authors: Noriho Sakamoto, Hiroshi Ishimoto, Tomoyuki Kakugawa, Minoru Satoh, Tomoko Hasegawa, Shin Tanaka, Atsuko Hara, Shota Nakashima, Hirokazu Yura, Takuto Miyamura, Hanako Koyama, Towako Morita, Seiko Nakamichi, Yasushi Obase, Yuji Ishimatsu and Hiroshi Mukae Tags: Research article Source Type: research