Vascular endothelial growth factor induces the migration of human airway smooth muscle cells by activating the RhoA/ROCK pathway
Airway remodeling due to increased airway smooth muscle cell (ASMC) mass, likely due to enhanced proliferation, hypertrophy, and migration, has been proven to be highly correlated with decreased lung function ... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 13, 2023 Category: Respiratory Medicine Authors: Chengtian Lv, Yuwen Huang, Ruirong Yan and Yuanmei Gao Tags: Research Source Type: research
The patient journey in Chronic Obstructive Pulmonary Disease (COPD): a human factors qualitative international study to understand the needs of people living with COPD
Chronic obstructive pulmonary disease (COPD) is a common condition that causes irreversible airway obstruction. Fatigue and exertional dyspnoea, for example, have a detrimental impact on the patient ’s daily li... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 13, 2023 Category: Respiratory Medicine Authors: Nicola Scichilone, Andrew Whittamore, Chris White, Elena Nudo, Massimo Savella and Marta Lombardini Tags: Research Source Type: research
Knockdown of MRPL35 promotes cell apoptosis and inhibits cell proliferation in non-small-cell lung cancer
Non-small cell lung cancer (NSCLC) is a major pathological type of lung cancer. However, its pathogenesis remains largely unclear. MRPL35 is a regulatory subunit of the mitoribosome, which can regulate the ass... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 13, 2023 Category: Respiratory Medicine Authors: Chengling Zhao, Lei Chen, Zhixin Jin, Haitao Liu, Chao Ma, Hangtian Zhou, Lingling Xu, Sihui Zhou, Yan Shi, Wei Li, Yuqing Chen, Chengli Dou and Xiaojing Wang Tags: Research Source Type: research
The increasing burden of asthma acute care in Singapore: an update on 15-year population-level evidence
In this study, we investigated the past 25-year trends of asthma-related hosp... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 12, 2023 Category: Respiratory Medicine Authors: Laura Huey Mien Lim, Wenjia Chen, Joseph Emil Amegadzie and Hui Fang Lim Tags: Research Source Type: research
Use of a combination of diaphragmatic ultrasound and muscle relaxation monitoring in predicting post-extubation adverse respiratory events among elderly patients in an anesthesia intensive care unit
The purpose of this study was to examine the feasibility of using a combination of diaphragmatic ultrasound and muscle relaxation monitoring in predicting adverse respiratory events after extubation among elde... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 12, 2023 Category: Respiratory Medicine Authors: Lun Huang, Bo Xia, Lei Cheng, Xian-Wen Hu, Li-Dong Zheng and Feng Cheng Tags: Research Source Type: research
Publisher Correction: Clinical features and risk factors of plastic bronchitis caused by Mycoplasma pneumoniae pneumonia in children
(Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 11, 2023 Category: Respiratory Medicine Authors: Lei Yang, Yuyan Zhang, Changqing Shen, Zhouhua Lu, Tongshu Hou, Fenghai Niu, Yuzhong Wang, Jun Ning and Ruihan Liu Tags: Publisher Correction Source Type: research
Adjunct prednisone in community-acquired pneumonia: 180-day outcome of a multicentre, double-blind, randomized, placebo-controlled trial
Several trials and meta-analyses found a benefit of adjunct corticosteroids for community-acquired pneumonia with respect to short-term outcome, but there is uncertainty about longer-term health effects. Herei... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 11, 2023 Category: Respiratory Medicine Authors: Claudine A. Blum, Eva A. Roethlisberger, Nicole Cesana-Nigro, Bettina Winzeler, Nicolas Rodondi, Manuel R. Blum, Matthias Briel, Beat Mueller, Mirjam Christ-Crain and Philipp Schuetz Tags: Research Source Type: research
The usual Interstitial pneumonia pattern in autoimmune rheumatic diseases
Usual Interstitial Pneumonia (UIP) is characterized by progression of lung parenchyma that may be observed in various autoimmune rheumatic diseases (ARDs), including rheumatoid arthritis and connective tissue ... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 11, 2023 Category: Respiratory Medicine Authors: Fabrizio Luppi, Andreina Manfredi, Paola Faverio, Michael Brun Andersen, Francesca Bono, Fabio Pagni, Carlo Salvarani, Elisabeth Bendstrup and Marco Sebastiani Tags: Review Source Type: research
Anticipating undiagnosed asthma in symptomatic adults with normal pre- and post-bronchodilator spirometry: a decision tool for bronchial challenge testing
Some patients with asthma demonstrate normal spirometry and remain undiagnosed without further testing. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 9, 2023 Category: Respiratory Medicine Authors: Sheojung Shin, George Alex Whitmore, Louis-Philippe Boulet, Marie- Ève Boulay, Andréanne Côté, Céline Bergeron, Catherine Lemière, M. Diane Lougheed, Katherine L. Vandemheen, Gonzalo G. Alvarez, Sunita Mulpuru and Shawn D. Aaron Tags: Research Source Type: research
Strain structure analysis of Mycobacterium tuberculosis circulating among HIV negative, positive and drug resistant TB patients attending chest clinics in Western Kenya
Despite global tuberculosis (TB) interventions, the disease remains one of the major public health concerns. Kenya is ranked 15th among 22 high burden TB countries globally. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 9, 2023 Category: Respiratory Medicine Authors: Martin O. Ogwang, Lameck Diero, Florence Ng ’ong’a, Gabriel Magoma, Lucy Mutharia, Mabel Imbuga and Caroline Ngugi Tags: Research Source Type: research
Comparison of breathing pattern and diaphragmatic motion in patients with unilateral cervical radiculopathy and asymptomatic group
The associations between neck pain and respiratory dysfunction were clarified in patients with neck pain. There is dearth of evidence on pulmonary dysfunction and diaphragmatic excursion in patients with unila... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 9, 2023 Category: Respiratory Medicine Authors: Raziyeh Yousefiyan, Amin Kordi Yoosefinejad, Reza Jalli and Iman Rezaei Tags: Research Source Type: research
The safety and efficacy of tislelizumab, alone or in combination with chemotherapy, for the treatment of non-small cell lung cancer: a systematic review of clinical trials
Tislelizumab is an anti-programmed death-1 (PD-1) monoclonal antibody with a construction that enables it to have a higher affinity to its target. We aimed to evaluate tislelizumab ’s safety and efficacy for tr... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 8, 2023 Category: Respiratory Medicine Authors: Amin Daei Sorkhabi, Mahta ZareDini, Asra Fazlollahi, Aila Sarkesh, Amirreza Naseri, Seyed Ehsan Mousavi, Seyed Aria Nejadghaderi, Mark J M Sullman, Ali-Asghar Kolahi and Saeid Safiri Tags: Research Source Type: research
Alveolar macrophage-derived gVPLA2 promotes ventilator-induced lung injury via the cPLA2/PGE2 pathway
Ventilator-induced lung injury (VILI) is a clinical complication of mechanical ventilation observed in patients with acute respiratory distress syndrome. It is characterized by inflammation mediated by inflamm... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 6, 2023 Category: Respiratory Medicine Authors: Hanghang Han, Qiuwen Xie, Rongge Shao, Jinju Li and Xueke Du Tags: Research Source Type: research
Development of a risk prediction model to predict the risk of hospitalization due to exacerbated asthma among adult asthma patients in a lower middle-income country
Asthma patients experience higher rates of hospitalizations due to exacerbations leaving a considerable clinical and economic burden on the healthcare system. The use of a simple, risk prediction tool offers a... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 6, 2023 Category: Respiratory Medicine Authors: Dhanusha Harshinie Punyadasa, Vindya Kumarapeli and Wijith Senaratne Tags: Research Source Type: research
Whole-exome sequencing explored mechanism of selpercatinib resistance in RET-rearranged lung adenocarcinoma transformation into small-cell lung cancer: a case report
Small cell transformation was one mechanism by which EGFR-mutation NSCLC acquired resistance after tyrosine kinase inhibitors (TKIs) treatment. A few reports of small cell transformation occurred in other oncogen... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 6, 2023 Category: Respiratory Medicine Authors: Yan Peng, Zhu Zheng, Wang Zewen, Liu Yanan, Zhang Mingyan and Sun Meili Tags: Case Report Source Type: research
