Mendelian randomization analysis suggests no causal influence of gastroesophageal reflux disease on the susceptibility and prognosis of idiopathic pulmonary fibrosis
The relationship between gastroesophageal reflux disease (GERD) and the susceptibility as well as the prognosis of idiopathic pulmonary fibrosis (IPF) has been previously suggested, with the potential confound... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 21, 2023 Category: Respiratory Medicine Authors: Di Sun and Qiao Ye Tags: Research Source Type: research

SNP (A   >  G - rs13057211) but not GT(n) polymorphism in HMOX-1 promotor gene is associated with COVID-19 mortality
COVID-19 causes severe inflammatory respiratory distress syndrome. The global pandemic caused millions of cases of morbidity and mortality worldwide. Patients may present with variable symptoms including dyspn... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 21, 2023 Category: Respiratory Medicine Authors: Kerolos Fares, Mona K. El-Deeb, Omar Elsammak, Amged Ouf, Hesham Mahmoud Sayd Saeed, Ayman Baess, Mohamed Elsammak and Eman El-Attar Tags: Research Source Type: research

A scoring model based on clinical factors to predict postoperative moderate to severe acute respiratory distress syndrome in Stanford type A aortic dissection
Postoperative acute respiratory distress syndrome (ARDS) after type A aortic dissection is common and has high mortality. However, it is not clear which patients are at high risk of ARDS and an early predictio... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 21, 2023 Category: Respiratory Medicine Authors: Maozhou Wang, Songhao Jia, Xin Pu, Lizhong Sun, Yuyong Liu, Ming Gong and Hongjia Zhang Tags: Research Source Type: research

Long non-coding RNA SNHG4 aggravates cigarette smoke-induced COPD by regulating miR-144-3p/EZH2 axis
The purpose of this study was to explore the expression level of SNHG4 in patients with COPD and its diagnostic value in COPD, to probe the biological function of SNHG4 in COPD at the cellular level, and to re... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 19, 2023 Category: Respiratory Medicine Authors: Benyan Song and Yusi Chen Tags: Research Source Type: research

Elevated level of serum human epididymis protein 4 (HE4) predicts disease severity and mortality in COVID-19 pneumonia
We retrospectively analyzed serum level of human epididymis protein 4 (HE4) as a pulmonary inflammatory biomarker in patients with COVID-19 pneumonia in association with disease severity and outcome. (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 16, 2023 Category: Respiratory Medicine Authors: Ren áta Sütő, Marianna Pócsi, Zsolt Szabó, Zsolt Fejes, Gergely Ivády, György Kerekes, Miklós Fagyas, Attila Nagy, Zoltán Szentkereszty, János Kappelmayer and Béla Nagy Jr. Tags: Research Source Type: research

Safety and efficacy of cryobiopsy for the diagnosis of lymphangioleiomyomatosis compared with forceps biopsy and surgical lung biopsy
Transbronchial lung forceps biopsy (TBFB) is recommended before a surgical lung biopsy (SLB) when a definitive diagnosis of lymphangioleiomyomatosis (LAM) is required for patients without any additional confir... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 15, 2023 Category: Respiratory Medicine Authors: Yao Yao, Xiaobo Chen, Huanjie Chen, Zhulin Xiao and Shiyue Li Tags: Research Source Type: research

Establishment of a prognosis prediction model for lung squamous cell carcinoma related to PET/CT: basing on immunogenic cell death-related lncRNA
Immunogenic cell death (ICD) stimulates adaptive immunity and holds significant promise in cancer therapy. Nevertheless, the influence of ICD-associated long non-coding RNAs (lncRNAs) on the prognosis of patie... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 15, 2023 Category: Respiratory Medicine Authors: Yu Han, Zhiqiang Dong, Yu Xing, Yingying Zhan, Jinhai Zou and Xiaodong Wang Tags: Research Source Type: research

Publisher Correction: Factors associated with overdiagnosis of benign pulmonary nodules as malignancy: a retrospective cohort study
(Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 14, 2023 Category: Respiratory Medicine Authors: Xirui Duan, Zhiqiang Ouyang, Shasha Bao, Lu Yang, Ailin Deng, Guangrong Zheng, Yu Zhu, Guochen Li, Jixiang Chu and Chengde Liao Tags: Publisher Correction Source Type: research

Cellular senescence contributes to mechanical ventilation-induced diaphragm dysfunction by upregulating p53 signalling pathways
Mechanical ventilation can cause acute atrophy and injury in the diaphragm, which are related to adverse clinical results. However, the underlying mechanisms of ventilation-induced diaphragm dysfunction (VIDD)... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 14, 2023 Category: Respiratory Medicine Authors: Weimin Shen, Ye Jiang, Ying Xu, Xiaoli Qian, Jianwei Jia, Yuejia Ding, Yuhan He, Qing Pan, Jinyang Zhuang, Huiqing Ge and Peifeng Xu Tags: Research Source Type: research

Effects of prone positioning on ARDS outcomes of trauma and surgical patients: a systematic review and meta-analysis
Prone position is an option for rescue therapy for acute respiratory distress syndrome. However, there are limited relevant data among trauma and surgical patients, who may be at increased risk for complicatio... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 13, 2023 Category: Respiratory Medicine Authors: Vorakamol Phoophiboon, Natthida Owattanapanich, Weerapat Owattanapanich and Morgan Schellenberg Tags: Research Source Type: research

Vascular endothelial growth factor induces the migration of human airway smooth muscle cells by activating the RhoA/ROCK pathway
Airway remodeling due to increased airway smooth muscle cell (ASMC) mass, likely due to enhanced proliferation, hypertrophy, and migration, has been proven to be highly correlated with decreased lung function ... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 13, 2023 Category: Respiratory Medicine Authors: Chengtian Lv, Yuwen Huang, Ruirong Yan and Yuanmei Gao Tags: Research Source Type: research

The patient journey in Chronic Obstructive Pulmonary Disease (COPD): a human factors qualitative international study to understand the needs of people living with COPD
Chronic obstructive pulmonary disease (COPD) is a common condition that causes irreversible airway obstruction. Fatigue and exertional dyspnoea, for example, have a detrimental impact on the patient ’s daily li... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 13, 2023 Category: Respiratory Medicine Authors: Nicola Scichilone, Andrew Whittamore, Chris White, Elena Nudo, Massimo Savella and Marta Lombardini Tags: Research Source Type: research

Knockdown of MRPL35 promotes cell apoptosis and inhibits cell proliferation in non-small-cell lung cancer
Non-small cell lung cancer (NSCLC) is a major pathological type of lung cancer. However, its pathogenesis remains largely unclear. MRPL35 is a regulatory subunit of the mitoribosome, which can regulate the ass... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 13, 2023 Category: Respiratory Medicine Authors: Chengling Zhao, Lei Chen, Zhixin Jin, Haitao Liu, Chao Ma, Hangtian Zhou, Lingling Xu, Sihui Zhou, Yan Shi, Wei Li, Yuqing Chen, Chengli Dou and Xiaojing Wang Tags: Research Source Type: research

The increasing burden of asthma acute care in Singapore: an update on 15-year population-level evidence
In this study, we investigated the past 25-year trends of asthma-related hosp... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 12, 2023 Category: Respiratory Medicine Authors: Laura Huey Mien Lim, Wenjia Chen, Joseph Emil Amegadzie and Hui Fang Lim Tags: Research Source Type: research

Use of a combination of diaphragmatic ultrasound and muscle relaxation monitoring in predicting post-extubation adverse respiratory events among elderly patients in an anesthesia intensive care unit
The purpose of this study was to examine the feasibility of using a combination of diaphragmatic ultrasound and muscle relaxation monitoring in predicting adverse respiratory events after extubation among elde... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - December 12, 2023 Category: Respiratory Medicine Authors: Lun Huang, Bo Xia, Lei Cheng, Xian-Wen Hu, Li-Dong Zheng and Feng Cheng Tags: Research Source Type: research