Co-designing care for multimorbidity: a systematic review
The co-design of health care enables patient-centredness by partnering patients, clinicians and other stakeholders together to create services. (Source: BMC Medicine)
Source: BMC Medicine - February 7, 2024 Category: Internal Medicine Authors: Jennifer Sumner, Celeste Wen Ting Ng, Kimberly Ee Lin Teo, Adena Li Tyin Peh and Yee Wei Lim Tags: Research article Source Type: research

Effects of 6-month customized home-based exercise on motor development, bone strength, and parental stress in children with simple congenital heart disease: a single-blinded randomized clinical trial
New “noncardiac” problems in children with congenital heart disease (CHD), such as developmental delay or long-term neurodevelopmental impairments, have attracted considerable attention in recent years. It is ... (Source: BMC Medicine)
Source: BMC Medicine - February 6, 2024 Category: Internal Medicine Authors: Qing Du, Xin Li, Zhaoxi Wang, Sun Chen, Xi Zhang, Juping Liang, Haibin Guo, Nan Chen, Hong Yu, Xiaoqing Zhu, Xuan Zhou and Kun Sun Tags: Research article Source Type: research

Ethnicity-specific blood pressure thresholds based on cardiovascular and renal complications: a prospective study in the UK Biobank
The appropriateness of hypertension thresholds for triggering action to prevent cardiovascular and renal complications among non-White populations in the UK is subject to question. Our objective was to establi... (Source: BMC Medicine)
Source: BMC Medicine - February 5, 2024 Category: Internal Medicine Authors: Donghan Su, Huanhuan Yang, Zekun Chen, Yuhao Kong, Xiaona Na, Queran Lin, Ai Zhao, Yan Zheng, Yanan Ma, Xiaoyu Li and Zhihui Li Tags: Research article Source Type: research

PCDHGB7 hypermethylation-based Cervical cancer Methylation (CerMe) detection for the triage of high-risk human papillomavirus-positive women: a prospective cohort study
Implementation of high-risk human papillomavirus (hrHPV) screening has greatly reduced the incidence and mortality of cervical cancer. However, a triage strategy that is effective, noninvasive, and independent... (Source: BMC Medicine)
Source: BMC Medicine - February 5, 2024 Category: Internal Medicine Authors: Dan Cao, Zhicong Yang, Shihua Dong, Yuhong Li, Zhanrui Mao, Qi Lu, Peng Xu, Minfang Shao, Lei Pan, Xu Han, Jiangjing Yuan, Qiong Fan, Lei Chen, Yanzhong Wang, Weipei Zhu, Wenqiang Yu & hellip; Tags: Research article Source Type: research

Artificial intelligence in the risk prediction models of cardiovascular disease and development of an independent validation screening tool: a systematic review
A comprehensive overview of artificial intelligence (AI) for cardiovascular disease (CVD) prediction and a screening tool of AI models (AI-Ms) for independent external validation are lacking. This systematic r... (Source: BMC Medicine)
Source: BMC Medicine - February 5, 2024 Category: Internal Medicine Authors: Yue Cai, Yu-Qing Cai, Li-Ying Tang, Yi-Han Wang, Mengchun Gong, Tian-Ci Jing, Hui-Jun Li, Jesse Li-Ling, Wei Hu, Zhihua Yin, Da-Xin Gong and Guang-Wei Zhang Tags: Research article Source Type: research

Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth
Abnormal placental development is a significant factor contributing to perinatal morbidity and mortality, affecting approximately 5 –7% of pregnant women. Trophoblast syncytialization plays a pivotal role in th... (Source: BMC Medicine)
Source: BMC Medicine - February 5, 2024 Category: Internal Medicine Authors: Jiayi Wu, Chuanmei Qin, Fuju Tian, Xueqing Liu, Jianing Hu, Fan Wu, Cailian Chen and Yi Lin Tags: Research article Source Type: research

Substantial health and economic burden of COVID-19 during the year after acute illness among US adults not at high risk of severe COVID-19
Patients recovering from SARS-CoV-2 infection and acute COVID-19 illness can experience a range of long-term post-acute effects. The potential clinical and economic burden of these outcomes in the USA is uncle... (Source: BMC Medicine)
Source: BMC Medicine - February 2, 2024 Category: Internal Medicine Authors: Amie Scott, Wajeeha Ansari, Richard Chambers, Maya Reimbaeva, Tomasz Mikolajczyk, Michael Benigno, Florin Draica and Joanna Atkinson Tags: Research article Source Type: research

Daily routine disruptions and psychiatric symptoms amid COVID-19: a systematic review and meta-analysis of data from 0.9 million individuals in 32 countries
There is currently a deficit of knowledge about how to define, quantify, and measure different aspects of daily routine disruptions amid large-scale disasters like COVID-19, and which psychiatric symptoms were... (Source: BMC Medicine)
Source: BMC Medicine - February 2, 2024 Category: Internal Medicine Authors: Huinan Liu, Tiffany Junchen Tao, Selina Kit Yi Chan, Jeremy Chi Him Ma, Abby Yan Tung Lau, Ernest Tsun Fung Yeung, Stevan E. Hobfoll and Wai Kai Hou Tags: Research article Source Type: research

Maternal smoking, nutritional factors at different life stage, and the risk of incident type 2 diabetes: a prospective study of the UK Biobank
This study aims to investigate potential interactions between maternal smoking around birth (MSAB) and type 2 diabetes (T2D) pathway-specific genetic risks in relation to the development of T2D in offspring. A... (Source: BMC Medicine)
Source: BMC Medicine - February 2, 2024 Category: Internal Medicine Authors: Wenbo Jiang, Yiwei Tang, Ruiming Yang, Yujia Long, Changhao Sun, Tianshu Han and Wei Wei Tags: Research article Source Type: research

Strategies for addressing the needs of children with or at risk of developmental disabilities in early childhood by 2030: a systematic umbrella review
There are over 53million children worldwide under five with developmental disabilities who require effective interventions to support their health and well-being. However, challenges in delivering intervention... (Source: BMC Medicine)
Source: BMC Medicine - February 2, 2024 Category: Internal Medicine Authors: Tracey Smythe, Nathaniel Scherer, Carol Nanyunja, Cally J. Tann and Bolajoko O. Olusanya Tags: Research article Source Type: research

Real-world nudging, pricing, and mobile physical activity coaching was insufficient to improve lifestyle behaviours and cardiometabolic health: the Supreme Nudge parallel cluster-randomised controlled supermarket trial
Context-specific interventions may contribute to sustained behaviour change and improved health outcomes. We evaluated the real-world effects of supermarket nudging and pricing strategies and mobile physical a... (Source: BMC Medicine)
Source: BMC Medicine - February 2, 2024 Category: Internal Medicine Authors: Josine M. Stuber, Joreintje D. Mackenbach, Gert-Jan de Bruijn, Marleen Gillebaart, Jody C. Hoenink, C édric N. H. Middel, Denise T. D. de Ridder, Yvonne T. van der Schouw, Edith G. Smit, Elizabeth Velema, Anne L. Vos, Wilma E. Waterlander, Jeroen Lakerve Tags: Research article Source Type: research

Mapping heterogeneity in family planning indicators in Burkina Faso, Kenya, and Nigeria, 2000 –2020
Family planning is fundamental to women ’s reproductive health and is a basic human right. Global targets such as Sustainable Development Goal 3 (specifically, Target 3.7) have been established to promote unive... (Source: BMC Medicine)
Source: BMC Medicine - February 1, 2024 Category: Internal Medicine Tags: Research article Source Type: research

Immune checkpoint inhibitors in cancer: the increased risk of atherosclerotic cardiovascular disease events and progression of coronary artery calcium
Immune checkpoint inhibitors (ICIs) have contributed to a significant advancement in the treatment of cancer, leading to improved clinical outcomes in many individuals with advanced disease. Both preclinical a... (Source: BMC Medicine)
Source: BMC Medicine - January 31, 2024 Category: Internal Medicine Authors: Bingxin Gong, Yusheng Guo, Yi Li, Jing Wang, Guofeng Zhou, Yong-hao Chen, Tong Nie, Ming Yang, Kun Luo, Chuansheng Zheng, Feng Pan, Bo Liang and Lian Yang Tags: Research article Source Type: research

Impact of preconception and antenatal supplementation with myo-inositol, probiotics, and micronutrients on offspring BMI and weight gain over the first 2 years
Nutritional intervention preconception and throughout pregnancy has been proposed as an approach to promoting healthy postnatal weight gain in the offspring but few randomised trials have examined this. (Source: BMC Medicine)
Source: BMC Medicine - January 30, 2024 Category: Internal Medicine Authors: Jaz Lyons-Reid, Jos é G. B. Derraik, Timothy Kenealy, Benjamin B. Albert, J. Manuel Ramos Nieves, Cathriona R. Monnard, Phil Titcombe, Heidi Nield, Sheila J. Barton, Sarah El-Heis, Elizabeth Tham, Keith M. Godfrey, Shiao-Yng Chan and Wayne S. Cutfield Tags: Research article Source Type: research

Isolating the effect of confounding from the observed survival benefit of screening participants — a methodological approach illustrated by data from the German mammography screening programme
Mammography screening programmes (MSP) aim to reduce breast cancer mortality by shifting diagnoses to earlier stages. However, it is difficult to evaluate the effectiveness of current MSP because analyses can ... (Source: BMC Medicine)
Source: BMC Medicine - January 30, 2024 Category: Internal Medicine Authors: Laura Buschmann, Ina Wellmann, Nadine Bonberg, J ürgen Wellmann, Hans-Werner Hense, André Karch and Heike Minnerup Tags: Research article Source Type: research