Breastfeeding is associated with enhanced intestinal gluconeogenesis in infants
Breastfeeding (BF) confers metabolic benefits to infants, including reducing risks of metabolic syndrome such as obesity and diabetes later in life. However, the underlying mechanism is not yet fully understoo... (Source: BMC Medicine)
Source: BMC Medicine - March 7, 2024 Category: Internal Medicine Authors: Duan Ni, Jian Tan, Laurence Macia and Ralph Nanan Tags: Correspondence Source Type: research
Camrelizumab plus gemcitabine and oxaliplatin for relapsed or refractory classical Hodgkin lymphoma: a phase II trial
Classical Hodgkin lymphoma (cHL) is a highly curable disease, while novel therapy is needed for refractory or relapsed (R/R) patients. This phase II trial aimed to evaluate the role of camrelizumab plus gemcit... (Source: BMC Medicine)
Source: BMC Medicine - March 7, 2024 Category: Internal Medicine Authors: Yanfei Liu, Lingyan Ping, Yuqin Song, Yongjing Tang, Wen Zheng, Weiping Liu, Zhitao Ying, Chen Zhang, Meng Wu, Feier Feng, Ningjing Lin, Meifeng Tu, Jun Zhu and Yan Xie Tags: Research article Source Type: research
Influence of lack of blinding on the estimation of medication-related harms: a retrospective cohort study of randomized controlled trials
Empirical evidence suggests that lack of blinding may be associated with biased estimates of treatment benefit in randomized controlled trials, but the influence on medication-related harms is not well-recogni... (Source: BMC Medicine)
Source: BMC Medicine - March 7, 2024 Category: Internal Medicine Authors: Chang Xu, Fengying Zhang, Suhail A. R. Doi, Luis Furuya-Kanamori, Lifeng Lin, Haitao Chu, Xi Yang, Sheyu Li, Liliane Zorzela, Su Golder, Yoon Loke and Sunita Vohra Tags: Research article Source Type: research
A self-controlled case series study to measure the risk of SARS-CoV-2 infection associated with attendance at sporting and cultural events: the UK Events Research Programme events
In 2021, whilst societies were emerging from major social restrictions during the SARS-CoV-2 pandemic, the UK government instigated an Events Research Programme to examine the risk of COVID-19 transmission fro... (Source: BMC Medicine)
Source: BMC Medicine - March 6, 2024 Category: Internal Medicine Authors: Ian J. Douglas, Jerlyn Peh, Kathryn E. Mansfield, Anna Trelfa, Tom Fowler, Matthew Boulter, Paul Cleary, Jenifer Smith and W. John Edmunds Tags: Research article Source Type: research
Global epidemiology of type 2 diabetes in patients with NAFLD or MAFLD: a systematic review and meta-analysis
Non-alcoholic fatty liver disease (NAFLD) and metabolic-associated fatty liver disease (MAFLD) shares common pathophysiological mechanisms with type 2 diabetes, making them significant risk factors for type 2 ... (Source: BMC Medicine)
Source: BMC Medicine - March 6, 2024 Category: Internal Medicine Authors: Limin Cao, Yu An, Huiyuan Liu, Jinguo Jiang, Wenqi Liu, Yuhan Zhou, Mengyuan Shi, Wei Dai, Yanling Lv, Yuhong Zhao, Yanhui Lu, Liangkai Chen and Yang Xia Tags: Research article Source Type: research
Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data
This study invest... (Source: BMC Medicine)
Source: BMC Medicine - March 6, 2024 Category: Internal Medicine Authors: Szu-Han Chen, Miaw-Chwen Lee and Christy Pu Tags: Research article Source Type: research
Carbohydrate quality, not quantity, linked to reduced colorectal cancer incidence and mortality in US populations: evidence from a prospective study
Carbohydrates have been implicated in colorectal cancer (CRC) risk, but the specific impact of carbohydrate quality and quantity on CRC susceptibility in US populations remains unclear. (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Yi Xiao, Ling Xiang, Yahui Jiang, Yunhao Tang, Haitao Gu, Yaxu Wang and Linglong Peng Tags: Research article Source Type: research
Subsidized gestational diabetes mellitus screening and management program in rural China: a pragmatic multicenter, randomized controlled trial
This study aimed to evaluate the effectiveness of... (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Tingting Xu, Qing Xia, Xiaozhen Lai, Kun He, Dazhi Fan, Liangkun Ma and Hai Fang Tags: Research article Source Type: research
The role of lifestyle in the association between long-term ambient air pollution exposure and cardiovascular disease: a national cohort study in China
Cardiovascular disease (CVD) caused by air pollution poses a considerable burden on public health. We aim to examine whether lifestyle factors mediate the associations of air pollutant exposure with the risk o... (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Xiangming Hu, Luke D. Knibbs, Yingling Zhou, Yanqiu Ou, Guang-Hui Dong and Haojian Dong Tags: Research article Source Type: research
Autoimmune diseases and adverse pregnancy outcomes: an umbrella review
There is a high prevalence of autoimmune conditions in women specially in the reproductive years; thus, the association with adverse pregnancy outcomes has been widely studied. However, few autoimmune conditio... (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Megha Singh, Steven Wambua, Siang Ing Lee, Kelvin Okoth, Zhaonan Wang, Fathima Fazla Ahamed Fayaz, Kelly-Ann Eastwood, Catherine Nelson-Piercy, John A. Reynolds, Krishnarajah Nirantharakumar and Francesca Crowe Tags: Research article Source Type: research
Thrombospondin 1 enhances systemic inflammation and disease severity in acute-on-chronic liver failure
The key role of thrombospondin 1 (THBS1) in the pathogenesis of acute-on-chronic liver failure (ACLF) is unclear. Here, we present a transcriptome approach to evaluate THBS1 as a potential biomarker in ACLF di... (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Hozeifa Mohamed Hassan, Xi Liang, Jiaojiao Xin, Yingyan Lu, Qun Cai, Dongyan Shi, Keke Ren, Jun Li, Qi Chen, Jiang Li, Peng Li, Beibei Guo, Hui Yang, Jinjin Luo, Heng Yao, Xingping Zhou & hellip; Tags: Research article Source Type: research
Plasma metabolites and risk of seven cancers: a two-sample Mendelian randomization study among European descendants
While circulating metabolites have been increasingly linked to cancer risk, the causality underlying these associations remains largely uninterrogated. (Source: BMC Medicine)
Source: BMC Medicine - March 4, 2024 Category: Internal Medicine Authors: Yaxin Chen, Yufang Xie, Hang Ci, Zhengpei Cheng, Yongjie Kuang, Shuqing Li, Gang Wang, Yawen Qi, Jun Tang, Dan Liu, Weimin Li and Yaohua Yang Tags: Research article Source Type: research
Exploring the Smoking-Epilepsy Nexus: a systematic review and meta-analysis of observational studies
Epilepsy, characterized by recurrent unprovoked seizures, poses significant challenges to affected individuals globally. While several established risk factors for epilepsy exist, the association with cigarett... (Source: BMC Medicine)
Source: BMC Medicine - March 4, 2024 Category: Internal Medicine Authors: Yerin Kang, Sieun Kim, Yunah Jung, Dai Sik Ko, Hyun-Woo Kim, Jung-Pil Yoon, Sunghwan Cho, Tae-Jin Song, Kihun Kim, Eunjeong Son and Yun Hak Kim Tags: Research article Source Type: research
Common and distinct cortical thickness alterations in youth with autism spectrum disorder and attention-deficit/hyperactivity disorder
Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders with overlapping behavioral features and genetic etiology. While brain cortical thickness (CT... (Source: BMC Medicine)
Source: BMC Medicine - March 4, 2024 Category: Internal Medicine Authors: Wanfang You, Qian Li, Lizhou Chen, Ning He, Yuanyuan Li, Fenghua Long, Yaxuan Wang, Yufei Chen, Robert K. McNamara, John A. Sweeney, Melissa P. DelBello, Qiyong Gong and Fei Li Tags: Research article Source Type: research
Association between patient ethnicity and prostate cancer diagnosis following a prostate-specific antigen test: a cohort study of 730,000 men in primary care in the UK
Black men have higher prostate-specific antigen (PSA) levels and higher prostate cancer incidence and mortality than White men, while Asian men tend to have lower prostate cancer incidence and mortality than W... (Source: BMC Medicine)
Source: BMC Medicine - March 1, 2024 Category: Internal Medicine Authors: Liz Down, Melissa Barlow, Sarah E. R. Bailey, Luke T. A. Mounce, Samuel W. D. Merriel, Jessica Watson and Tanimola Martins Tags: Research article Source Type: research
