The influence of n-3 polyunsaturated fatty acids on cognitive function in individuals without dementia: a systematic review and dose –response meta-analysis
Omega-3 polyunsaturated fatty acids (n-3 PUFA) have been suggested as a cognitive enhancing agent, though their effect is doubtful. We aimed to examine the effect of n-3 PUFA on the cognitive function of middl... (Source: BMC Medicine)
Source: BMC Medicine - March 12, 2024 Category: Internal Medicine Authors: Seung Wan Suh, Eunji Lim, Suh-Yuhn Burm, Hyungji Lee, Jong Bin Bae, Ji Won Han and Ki Woong Kim Tags: Research article Source Type: research

Correlates of protection and determinants of SARS-CoV-2 breakthrough infections 1 year after third dose vaccination
The emergence of new SARS-CoV-2 variants and the waning of immunity raise concerns about vaccine effectiveness and protection against COVID-19. While antibody response has been shown to correlate with the risk... (Source: BMC Medicine)
Source: BMC Medicine - March 8, 2024 Category: Internal Medicine Authors: Carla Mart ín Pérez, Ruth Aguilar, Alfons Jiménez, Gemma Salmerón, Mar Canyelles, Rocío Rubio, Marta Vidal, Inocencia Cuamba, Diana Barrios, Natalia Díaz, Rebeca Santano, Pau Serra, Pere Santamaria, Luis Izquierdo, Antoni Trilla, Anna Vilella & hell Tags: Research article Source Type: research

Gut microbiome features and metabolites in non-alcoholic fatty liver disease among community-dwelling middle-aged and older adults
The specific microbiota and associated metabolites linked to non-alcoholic fatty liver disease (NAFLD) are still controversial. Thus, we aimed to understand how the core gut microbiota and metabolites impact N... (Source: BMC Medicine)
Source: BMC Medicine - March 7, 2024 Category: Internal Medicine Authors: Fangfang Zeng, Xin Su, Xinxiu Liang, Minqi Liao, Haili Zhong, Jinjian Xu, Wanglong Gou, Xiangzhou Zhang, Luqi Shen, Ju-Sheng Zheng and Yu-ming Chen Tags: Research article Source Type: research

Breastfeeding is associated with enhanced intestinal gluconeogenesis in infants
Breastfeeding (BF) confers metabolic benefits to infants, including reducing risks of metabolic syndrome such as obesity and diabetes later in life. However, the underlying mechanism is not yet fully understoo... (Source: BMC Medicine)
Source: BMC Medicine - March 7, 2024 Category: Internal Medicine Authors: Duan Ni, Jian Tan, Laurence Macia and Ralph Nanan Tags: Correspondence Source Type: research

Camrelizumab plus gemcitabine and oxaliplatin for relapsed or refractory classical Hodgkin lymphoma: a phase II trial
Classical Hodgkin lymphoma (cHL) is a highly curable disease, while novel therapy is needed for refractory or relapsed (R/R) patients. This phase II trial aimed to evaluate the role of camrelizumab plus gemcit... (Source: BMC Medicine)
Source: BMC Medicine - March 7, 2024 Category: Internal Medicine Authors: Yanfei Liu, Lingyan Ping, Yuqin Song, Yongjing Tang, Wen Zheng, Weiping Liu, Zhitao Ying, Chen Zhang, Meng Wu, Feier Feng, Ningjing Lin, Meifeng Tu, Jun Zhu and Yan Xie Tags: Research article Source Type: research

Influence of lack of blinding on the estimation of medication-related harms: a retrospective cohort study of randomized controlled trials
Empirical evidence suggests that lack of blinding may be associated with biased estimates of treatment benefit in randomized controlled trials, but the influence on medication-related harms is not well-recogni... (Source: BMC Medicine)
Source: BMC Medicine - March 7, 2024 Category: Internal Medicine Authors: Chang Xu, Fengying Zhang, Suhail A. R. Doi, Luis Furuya-Kanamori, Lifeng Lin, Haitao Chu, Xi Yang, Sheyu Li, Liliane Zorzela, Su Golder, Yoon Loke and Sunita Vohra Tags: Research article Source Type: research

A self-controlled case series study to measure the risk of SARS-CoV-2 infection associated with attendance at sporting and cultural events: the UK Events Research Programme events
In 2021, whilst societies were emerging from major social restrictions during the SARS-CoV-2 pandemic, the UK government instigated an Events Research Programme to examine the risk of COVID-19 transmission fro... (Source: BMC Medicine)
Source: BMC Medicine - March 6, 2024 Category: Internal Medicine Authors: Ian J. Douglas, Jerlyn Peh, Kathryn E. Mansfield, Anna Trelfa, Tom Fowler, Matthew Boulter, Paul Cleary, Jenifer Smith and W. John Edmunds Tags: Research article Source Type: research

Global epidemiology of type 2 diabetes in patients with NAFLD or MAFLD: a systematic review and meta-analysis
Non-alcoholic fatty liver disease (NAFLD) and metabolic-associated fatty liver disease (MAFLD) shares common pathophysiological mechanisms with type 2 diabetes, making them significant risk factors for type 2 ... (Source: BMC Medicine)
Source: BMC Medicine - March 6, 2024 Category: Internal Medicine Authors: Limin Cao, Yu An, Huiyuan Liu, Jinguo Jiang, Wenqi Liu, Yuhan Zhou, Mengyuan Shi, Wei Dai, Yanling Lv, Yuhong Zhao, Yanhui Lu, Liangkai Chen and Yang Xia Tags: Research article Source Type: research

Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data
This study invest... (Source: BMC Medicine)
Source: BMC Medicine - March 6, 2024 Category: Internal Medicine Authors: Szu-Han Chen, Miaw-Chwen Lee and Christy Pu Tags: Research article Source Type: research

Carbohydrate quality, not quantity, linked to reduced colorectal cancer incidence and mortality in US populations: evidence from a prospective study
Carbohydrates have been implicated in colorectal cancer (CRC) risk, but the specific impact of carbohydrate quality and quantity on CRC susceptibility in US populations remains unclear. (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Yi Xiao, Ling Xiang, Yahui Jiang, Yunhao Tang, Haitao Gu, Yaxu Wang and Linglong Peng Tags: Research article Source Type: research

Subsidized gestational diabetes mellitus screening and management program in rural China: a pragmatic multicenter, randomized controlled trial
This study aimed to evaluate the effectiveness of... (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Tingting Xu, Qing Xia, Xiaozhen Lai, Kun He, Dazhi Fan, Liangkun Ma and Hai Fang Tags: Research article Source Type: research

The role of lifestyle in the association between long-term ambient air pollution exposure and cardiovascular disease: a national cohort study in China
Cardiovascular disease (CVD) caused by air pollution poses a considerable burden on public health. We aim to examine whether lifestyle factors mediate the associations of air pollutant exposure with the risk o... (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Xiangming Hu, Luke D. Knibbs, Yingling Zhou, Yanqiu Ou, Guang-Hui Dong and Haojian Dong Tags: Research article Source Type: research

Autoimmune diseases and adverse pregnancy outcomes: an umbrella review
There is a high prevalence of autoimmune conditions in women specially in the reproductive years; thus, the association with adverse pregnancy outcomes has been widely studied. However, few autoimmune conditio... (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Megha Singh, Steven Wambua, Siang Ing Lee, Kelvin Okoth, Zhaonan Wang, Fathima Fazla Ahamed Fayaz, Kelly-Ann Eastwood, Catherine Nelson-Piercy, John A. Reynolds, Krishnarajah Nirantharakumar and Francesca Crowe Tags: Research article Source Type: research

Thrombospondin 1 enhances systemic inflammation and disease severity in acute-on-chronic liver failure
The key role of thrombospondin 1 (THBS1) in the pathogenesis of acute-on-chronic liver failure (ACLF) is unclear. Here, we present a transcriptome approach to evaluate THBS1 as a potential biomarker in ACLF di... (Source: BMC Medicine)
Source: BMC Medicine - March 5, 2024 Category: Internal Medicine Authors: Hozeifa Mohamed Hassan, Xi Liang, Jiaojiao Xin, Yingyan Lu, Qun Cai, Dongyan Shi, Keke Ren, Jun Li, Qi Chen, Jiang Li, Peng Li, Beibei Guo, Hui Yang, Jinjin Luo, Heng Yao, Xingping Zhou & hellip; Tags: Research article Source Type: research

Plasma metabolites and risk of seven cancers: a two-sample Mendelian randomization study among European descendants
While circulating metabolites have been increasingly linked to cancer risk, the causality underlying these associations remains largely uninterrogated. (Source: BMC Medicine)
Source: BMC Medicine - March 4, 2024 Category: Internal Medicine Authors: Yaxin Chen, Yufang Xie, Hang Ci, Zhengpei Cheng, Yongjie Kuang, Shuqing Li, Gang Wang, Yawen Qi, Jun Tang, Dan Liu, Weimin Li and Yaohua Yang Tags: Research article Source Type: research