Proteomic insights into the associations between obesity, lifestyle factors, and coronary artery disease
We aimed to investigate the protein pathways linking obesity and lifestyle factors to coronary artery disease (CAD). (Source: BMC Medicine)
Source: BMC Medicine - December 5, 2023 Category: Internal Medicine Authors: Fangkun Yang, Fengzhe Xu, Han Zhang, Dipender Gill, Susanna C. Larsson, Xue Li, Hanbin Cui and Shuai Yuan Tags: Research article Source Type: research
Prognostic value of pretreatment lymphocyte-to-monocyte ratio in patients with glioma: a meta-analysis
Many studies have explored the prognostic role of the lymphocyte-to-monocyte ratio (LMR) in patients with glioma, but the results have been inconsistent. We therefore conducted the current meta-analysis to ide... (Source: BMC Medicine)
Source: BMC Medicine - December 5, 2023 Category: Internal Medicine Authors: Yan Wang, Chu Xu and Zongxin Zhang Tags: Research article Source Type: research
Association between viral infections and glioma risk: a two-sample bidirectional Mendelian randomization analysis
Glioma is one of the leading types of brain tumor, but few etiologic factors of primary glioma have been identified. Previous observational research has shown an association between viral infection and glioma ... (Source: BMC Medicine)
Source: BMC Medicine - December 5, 2023 Category: Internal Medicine Authors: Sheng Zhong, Wenzhuo Yang, Zhiyun Zhang, Yangyiran Xie, Lin Pan, Jiaxin Ren, Fei Ren, Yifan Li, Haoqun Xie, Hongyu Chen, Davy Deng, Jie Lu, Hui Li, Bo Wu, Youqi Chen, Fei Peng & hellip; Tags: Research article Source Type: research
Predicting drug response from single-cell expression profiles of tumours
Intra-tumour heterogeneity (ITH) presents a significant obstacle in formulating effective treatment strategies in clinical practice. Single-cell RNA sequencing (scRNA-seq) has evolved as a powerful instrument ... (Source: BMC Medicine)
Source: BMC Medicine - December 1, 2023 Category: Internal Medicine Authors: Simona Pellecchia, Gaetano Viscido, Melania Franchini and Gennaro Gambardella Tags: Software Source Type: research
Coronary microvascular function in male physicians with burnout and job stress: an observational study
As a professional group, physicians are at increased risk of burnout and job stress, both of which are associated with an increased risk of coronary heart disease that is at least as high as that of other prof... (Source: BMC Medicine)
Source: BMC Medicine - December 1, 2023 Category: Internal Medicine Authors: Roland von K änel, Mary Princip, Sarah A. Holzgang, Chrysoula Garefa, Alexia Rossi, Dominik C. Benz, Andreas A. Giannopoulos, Philipp A. Kaufmann, Ronny R. Buechel, Claudia Zuccarella-Hackl and Aju P. Pazhenkottil Tags: Research article Source Type: research
Change of the vaginal microbiome with oral contraceptive therapy in women with polycystic ovary syndrome: a 6-month longitudinal cohort study
The association between the vaginal microbiome and polycystic ovary syndrome (PCOS) is reported, but the longitudinal changes in the vaginal microbiome that accompany oral contraceptive therapy have not been d... (Source: BMC Medicine)
Source: BMC Medicine - December 1, 2023 Category: Internal Medicine Authors: Xiang Hong, Pengfei Qin, Liting Gao, Lingling Huang, Yong Shi, Danhong Peng and Bei Wang Tags: Research article Source Type: research
Association between ethnicity and migration status with the prevalence of single and multiple long-term conditions in UK healthcare workers
Healthcare workers ’ (HCW) well-being has a direct effect on patient care. However, little is known about the prevalence and patterns of long-term medical conditions in HCWs, especially those from ethnic minori... (Source: BMC Medicine)
Source: BMC Medicine - November 30, 2023 Category: Internal Medicine Authors: Winifred Ekezie, Christopher A. Martin, Rebecca F. Baggaley, Lucy Teece, Joshua Nazareth, Daniel Pan, Shirley Sze, Luke Bryant, Katherine Woolf, Laura J. Gray, Kamlesh Khunti and Manish Pareek Tags: Research article Source Type: research
Dissemination of Registered COVID-19 Clinical Trials (DIRECCT): a cross-sectional study
This study aimed to examine when, and where, the results of COVID-19 clinical trials ... (Source: BMC Medicine)
Source: BMC Medicine - November 29, 2023 Category: Internal Medicine Authors: Maia Salholz-Hillel, Molly Pugh-Jones, Nicole Hildebrand, Tjada A. Schult, Johannes Schwietering, Peter Grabitz, Benjamin Gregory Carlisle, Ben Goldacre, Daniel Strech and Nicholas J. DeVito Tags: Research article Source Type: research
A pilot study of multi-antigen stimulated cell therapy-I plus camrelizumab and apatinib in patients with advanced bone and soft-tissue sarcomas
Cell-based immunotherapy shows the therapeutic potential in sarcomas, in addition to angiogenesis-targeted tyrosine kinase inhibitor (TKI) and immune checkpoint inhibitor (ICI). Multi-antigen stimulated cell ... (Source: BMC Medicine)
Source: BMC Medicine - November 29, 2023 Category: Internal Medicine Authors: Yan Zhou, Mei Li, Bing Zhang, Cheng Yang, Yaling Wang, Shuier Zheng, Lina Tang, Chenliang Zhou, Guowei Qian, Yujing Huang, Wenxi Yu, Hongtao Li, Yonggang Wang, Aina He, Zan Shen, Jianjun Zhang & hellip; Tags: Research article Source Type: research
Representativeness in health research studies: an audit of Greater Manchester Clinical Research Network studies between 2016 and 2021
There are increasing concerns that participants in health research in the UK are not representative of the UK population, risking widening health inequities. However, detailed information on the magnitude of t... (Source: BMC Medicine)
Source: BMC Medicine - November 29, 2023 Category: Internal Medicine Authors: Kathryn M. Abel, Maja R. Radoj čić, Archie Rayner, Rabia Butt, Pauline Whelan, Isaac Parr, Lauren F. Gledhill, Ashley Minchin, Peter Bower and Holly Hope Tags: Research article Source Type: research
Maternal glycemic status during pregnancy and mid-childhood plasma amino acid profiles: findings from a multi-ethnic Asian birth cohort
Increasing maternal glycaemia across the continuum during pregnancy may predispose offspring to subsequent cardiometabolic risk later in life. However, evidence of long-term impacts of maternal glycemic status... (Source: BMC Medicine)
Source: BMC Medicine - November 29, 2023 Category: Internal Medicine Authors: Mengjiao Liu, Shiao-Yng Chan, Johan G. Eriksson, Yap Seng Chong, Yung Seng Lee, Fabian Yap, Mary Foong-Fong Chong, Mya Thway Tint, Jiaxi Yang, David Burgner, Cuilin Zhang and Ling-Jun Li Tags: Research article Source Type: research
Clinical efficacy of sodium bicarbonate in treating pediatric metabolic acidosis with varying level of acid –base balance parameters: a real-world study
This study aims to investigate whether acid –base balance parameters should be a... (Source: BMC Medicine)
Source: BMC Medicine - November 29, 2023 Category: Internal Medicine Authors: Huaqing Liu, Yanmei Cao, Xiaoyan Xue, Zhenjiang Bai and Shuiyan Wu Tags: Research article Source Type: research
Adherence to the 2018 World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) Cancer Prevention Recommendations and risk of 14 lifestyle-related cancers in the UK Biobank prospective cohort study
This study investigate... (Source: BMC Medicine)
Source: BMC Medicine - November 28, 2023 Category: Internal Medicine Authors: Fiona C. Malcomson, Solange Parra-Soto, Frederick K. Ho, Liya Lu, Carlos Celis-Morales, Linda Sharp and John C. Mathers Tags: Research article Source Type: research
Radiomics in precision oncology: hype or ludum mutante
(Source: BMC Medicine)
Source: BMC Medicine - November 28, 2023 Category: Internal Medicine Authors: Shi Hui Tay, Xin Zhang and Melvin L. K. Chua Tags: Commentary Source Type: research
Identifying patterns of reported findings on long-term cardiac complications of COVID-19: a systematic review and meta-analysis
Prior reviews synthesized findings of studies on long-term cardiac complications of COVID-19. However, the reporting and methodological quality of these studies has not been systematically evaluated. Here, we ... (Source: BMC Medicine)
Source: BMC Medicine - November 28, 2023 Category: Internal Medicine Authors: Boya Guo, Chenya Zhao, Mike Z. He, Camilla Senter, Zhenwei Zhou, Jin Peng, Song Li, Annette L. Fitzpatrick, Sara Lindstr öm, Rebecca C. Stebbins, Grace A. Noppert and Chihua Li Tags: Review Source Type: research
