Self-collection of samples for group B streptococcus testing during pregnancy: a systematic review and meta-analysis
Sample self-collection for reproductive tract infection diagnosis has been found to offer greater convenience, privacy, autonomy, and expanded access to testing in non-pregnant adults. This review aimed to det... (Source: BMC Medicine)
Source: BMC Medicine - December 18, 2023 Category: Internal Medicine Authors: Sarah A. Borg, Jenny Cao, Phi-Yen Nguyen, Samia Aziz and Joshua P. Vogel Tags: Research article Source Type: research

Predictive model for epileptogenic tubers from all tubers in patients with tuberous sclerosis complex based on 18F-FDG PET: an 8-year single-centre study
More than half of patients with tuberous sclerosis complex (TSC) suffer from drug-resistant epilepsy (DRE), and resection surgery is the most effective way to control intractable epilepsy. Precise preoperative... (Source: BMC Medicine)
Source: BMC Medicine - December 18, 2023 Category: Internal Medicine Authors: Zhongke Wang, Yang Li, Zeng He, Shujing Li, Kaixuan Huang, Xianjun Shi, Xiaoqin Sun, Ruotong Ruan, Chun Cui, Ruodan Wang, Li Wang, Shengqing Lv, Chunqing Zhang, Zhonghong Liu, Hui Yang, Xiaolin Yang & hellip; Tags: Research article Source Type: research

Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study
Mental health conditions represent one of the major groups of non-transmissible diseases. Physical activity (PA) and sedentary time (ST) have been shown to affect mental health outcomes in opposite directions.... (Source: BMC Medicine)
Source: BMC Medicine - December 18, 2023 Category: Internal Medicine Authors: Francesco Casanova, Jessica O ’Loughlin, Vasilis Karageorgiou, Robin N. Beaumont, Jack Bowden, Andrew R. Wood and Jessica Tyrrell Tags: Research article Source Type: research

Prediction of acute kidney injury incidence following acute type A aortic dissection surgery with novel biomarkers: a prospective observational study
Acute kidney injury (AKI) is a prevalent complication following acute type A aortic dissection (ATAAD) surgery and is closely associated with unfavorable prognostic outcomes. Hence, the development of a robust... (Source: BMC Medicine)
Source: BMC Medicine - December 18, 2023 Category: Internal Medicine Authors: Zhigang Wang, Jingfang Xu, Yu Zhang, Cheng Chen, Chuiyu Kong, Lu Tang, Yi Jiang, Ronghuang Yu, Qiuyan Zong, Lifang Zhang and Dongjin Wang Tags: Research article Source Type: research

The citrate transporter SLC13A5 as a therapeutic target for kidney disease: evidence from Mendelian randomization to inform drug development
Solute carrier family 13 member 5 (SLC13A5) is a Na+-coupled citrate co-transporter that mediates entry of extracellular citrate into the cytosol. SLC13A5 inhibition has been proposed as a target for reducing pro... (Source: BMC Medicine)
Source: BMC Medicine - December 18, 2023 Category: Internal Medicine Authors: Dipender Gill, Loukas Zagkos, Rubinder Gill, Thomas Benzing, Jens Jordan, Andreas L. Birkenfeld, Stephen Burgess and Grit Zahn Tags: Research article Source Type: research

Performance measures of 8,169,869 examinations in the National Breast Cancer Screening Program in Taiwan, 2004 –2020
The benefits of mammographic screening have been shown to include a decrease in mortality due to breast cancer. Taiwan ’s Breast Cancer Screening Program is a national screening program that has offered biennia... (Source: BMC Medicine)
Source: BMC Medicine - December 15, 2023 Category: Internal Medicine Authors: Melissa Min-Szu Yao, Vu Pham Thao Vy, Tony Hsiu-Hsi Chen, Hsian-He Hsu, Giu-Cheng Hsu, Cindy S. Lee, Li-Ju Lin, Shu-Li Chia, Chao-Chun Wu, Wing P. Chan and Amy Ming-Fang Yen Tags: Research article Source Type: research

Have there been sustained impacts of the COVID-19 pandemic on trends in smoking prevalence, uptake, quitting, use of treatment, and relapse? A monthly population study in England, 2017 –2022
This study aimed to examine whether ... (Source: BMC Medicine)
Source: BMC Medicine - December 14, 2023 Category: Internal Medicine Authors: Sarah E. Jackson, Harry Tattan-Birch, Lion Shahab, Emma Beard and Jamie Brown Tags: Research article Source Type: research

Risk factors for preterm birth: an umbrella review of meta-analyses of observational studies
Preterm birth defined as delivery before 37 gestational weeks is a leading cause of neonatal and infant morbidity and mortality. The aim of this study is to summarize the evidence from meta-analyses of observa... (Source: BMC Medicine)
Source: BMC Medicine - December 13, 2023 Category: Internal Medicine Authors: Ioannis Mitrogiannis, Evangelos Evangelou, Athina Efthymiou, Theofilos Kanavos, Effrosyni Birbas, George Makrydimas and Stefania Papatheodorou Tags: Research article Source Type: research

Exploring multimorbidity profiles in middle-aged inpatients: a network-based comparative study of China and the United Kingdom
This study aims to identify the differences in comorbidity patterns in middle-aged inpatients from China and the United Kingdom (UK). (Source: BMC Medicine)
Source: BMC Medicine - December 13, 2023 Category: Internal Medicine Authors: Yining Bao, Pengyi Lu, Mengjie Wang, Xueli Zhang, Aowei Song, Xiaoyun Gu, Ting Ma, Shu Su, Lin Wang, Xianwen Shang, Zhuoting Zhu, Yuhang Zhai, Mingguang He, Zengbin Li, Hanting Liu, Christopher K. Fairley & hellip; Tags: Research article Source Type: research

Functional connectivity of cognition-related brain networks in adults with fetal alcohol syndrome
Fetal alcohol syndrome (FAS) can result in cognitive dysfunction. Cognitive functions affected are subserved by few functional brain networks. Functional connectivity (FC) in these networks can be assessed wit... (Source: BMC Medicine)
Source: BMC Medicine - December 13, 2023 Category: Internal Medicine Authors: Benedikt Sundermann, Reinhold Feldmann, Christian Mathys, Johanna M. H. Rau, Stefan Garde, Anna Braje, Josef Weglage and Bettina Pfleiderer Tags: Research article Source Type: research

Model-based evaluation of admission screening strategies for the detection and control of carbapenemase-producing Enterobacterales in the English hospital setting
Globally, detections of carbapenemase-producing Enterobacterales (CPE) colonisations and infections are increasing. The spread of these highly resistant bacteria poses a serious threat to public health. Howeve... (Source: BMC Medicine)
Source: BMC Medicine - December 12, 2023 Category: Internal Medicine Authors: Diane Pople, Theodore Kypraios, Tjibbe Donker, Nicole Stoesser, Anna C. Seale, Ryan George, Andrew Dodgson, Rachel Freeman, Russell Hope, Ann Sarah Walker, Susan Hopkins and Julie Robotham Tags: Research article Source Type: research

Construction of a risk stratification model integrating ctDNA to predict response and survival in neoadjuvant-treated breast cancer
The pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) of breast cancer is closely related to a better prognosis. However, there are no reliable indicators to accurately identify which pati... (Source: BMC Medicine)
Source: BMC Medicine - December 12, 2023 Category: Internal Medicine Authors: Zhaoyun Liu, Bo Yu, Mu Su, Chenxi Yuan, Cuicui Liu, Xinzhao Wang, Xiang Song, Chao Li, Fukai Wang, Jianli Ma, Meng Wu, Dawei Chen, Jinming Yu and Zhiyong Yu Tags: Research article Source Type: research

Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders
Major psychiatric disorders such as schizophrenia (SCZ) and bipolar disorder (BPD) are complex genetic mental illnesses. Their non-Mendelian features, such as those observed in monozygotic twins discordant for... (Source: BMC Medicine)
Source: BMC Medicine - December 12, 2023 Category: Internal Medicine Authors: Junping Ye, Zhanwang Huang, Qiyang Li, Zhongwei Li, Yuting Lan, Zhongju Wang, Chaoying Ni, Xiaohui Wu, Tingyun Jiang, Yujing Li, Qiong Yang, Junghwa Lim, Cun-Yan Ren, Meijun Jiang, Shufen Li, Peng Jin & hellip; Tags: Research article Source Type: research

Association between menstrual cycle phase and metabolites in healthy, regularly menstruating women in UK Biobank, and effect modification by inflammatory markers and risk factors for metabolic disease
Preliminary evidence demonstrates some parameters of metabolic control, including glycaemic control, lipid control and insulin resistance, vary across the menstrual cycle. However, the literature is inconsiste... (Source: BMC Medicine)
Source: BMC Medicine - December 8, 2023 Category: Internal Medicine Authors: Kirstin A. MacGregor, Frederick K. Ho, Carlos A. Celis-Morales, Jill P. Pell, Iain J. Gallagher and Colin N. Moran Tags: Research article Source Type: research

Association of genetic risk and lifestyle with pancreatic cancer and their age dependency: a large prospective cohort study in the UK Biobank
Pancreatic cancer (PC) is influenced by both genetic and lifestyle factors. However, further research is still needed to comprehensively clarify the relationships among lifestyle, genetic factors, their combin... (Source: BMC Medicine)
Source: BMC Medicine - December 8, 2023 Category: Internal Medicine Authors: Liangtang Zeng, Zhuo Wu, Jiabin Yang, Yu Zhou and Rufu Chen Tags: Research article Source Type: research