Associations between long-term night shift work and incidence of chronic obstructive pulmonary disease: a prospective cohort study of 277,059 UK Biobank participants
In this study, we aim to investigate relationships between long-te... (Source: BMC Medicine)
Source: BMC Medicine - January 16, 2024 Category: Internal Medicine Authors: Jia Li, Liangle Yang, Yuxin Yao, Pei Gu, Yujia Xie, Haoyu Yin, Mingyue Xue, Yu Jiang, Jianghong Dai and Jixuan Ma Tags: Research article Source Type: research
Exposure to residential green and blue space and the natural environment is associated with a lower incidence of psychiatric disorders in middle-aged and older adults: findings from the UK Biobank
There is increasing evidence for the role of environmental factors and exposure to the natural environment on a wide range of health outcomes. Whether exposure to green space, blue space, and the natural envir... (Source: BMC Medicine)
Source: BMC Medicine - January 15, 2024 Category: Internal Medicine Authors: Bao-Peng Liu, Rachel R. Huxley, Tamara Schikowski, Ke-Jia Hu, Qi Zhao and Cun-Xian Jia Tags: Research article Source Type: research
A network meta-analysis of efficacy and safety for first-line and second/further-line therapies in postmenopausal women with hormone receptor-positive, HER2-negative, advanced breast cancer
Hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR + /HER2 −) advanced breast cancer is a prevalent subtype among postmenopausal women. Despite the growing number of randomized cli... (Source: BMC Medicine)
Source: BMC Medicine - January 12, 2024 Category: Internal Medicine Authors: Hanqiao Shao, Mingye Zhao, Ai-Jia Guan, Taihang Shao, Dachuang Zhou, Guo Yu and Wenxi Tang Tags: Research article Source Type: research
First trans-diagnostic experiences with a novel micro-choice based concentrated group rehabilitation for patients with low back pain, long COVID, and type 2 diabetes: a pilot study
The health care is likely to break down unless we are able to increase the level of functioning for the growing number of patients with complex, chronic illnesses. Hence, novel high-capacity and cost-effective... (Source: BMC Medicine)
Source: BMC Medicine - January 11, 2024 Category: Internal Medicine Authors: Gerd Kvale, Eirik S øfteland, Marte Jürgensen, Ane Wilhelmsen-Langeland, Anne Haugstvedt, Sigurd William Hystad, Øystein Theodor Ødegaard-Olsen, Bernt Bøgvald Aarli, Sidsel Rykken and Bente Frisk Tags: Research article Source Type: research
Risks of digestive diseases in long COVID: evidence from a population-based cohort study
In the post-pandemic era, a wide range of COVID-19 sequelae is of growing health concern. However, the risks of digestive diseases in long COVID have not been comprehensively understood. To investigate the lon... (Source: BMC Medicine)
Source: BMC Medicine - January 10, 2024 Category: Internal Medicine Authors: Yuying Ma, Lijun Zhang, Rui Wei, Weiyu Dai, Ruijie Zeng, Dongling Luo, Rui Jiang, Zewei Zhuo, Qi Yang, Jingwei Li, Felix W Leung, Chongyang Duan, Weihong Sha and Hao Chen Tags: Research article Source Type: research
Trajectories of health conditions and their associations with the risk of cognitive impairment among older adults: insights from a national prospective cohort study
The associations between trajectories of different health conditions and cognitive impairment among older adults were unknown. Our cohort study aimed to investigate the impact of various trajectories, includin... (Source: BMC Medicine)
Source: BMC Medicine - January 10, 2024 Category: Internal Medicine Authors: Min Du, Liyuan Tao, Min Liu and Jue Liu Tags: Research article Source Type: research
Randomized controlled trial demonstrates novel tools to assess patient outcomes of Indigenous cultural safety training
Health care routinely fails Indigenous peoples and anti-Indigenous racism is common in clinical encounters. Clinical training programs aimed to enhance Indigenous cultural safety (ICS) rely on learner reported... (Source: BMC Medicine)
Source: BMC Medicine - January 9, 2024 Category: Internal Medicine Authors: Janet Smylie, Michael A. Rotondi, Sam Filipenko, William T. L. Cox, Diane Smylie, Cheryl Ward, Kristina Klopfer, Aisha K. Lofters, Braden O ’Neill, Melissa Graham, Linda Weber, Ali N. Damji, Patricia G. Devine, Jane Collins and Billie-Jo Hardy Tags: Research article Source Type: research
Long-term outcomes of young, node-negative, chemotherapy-na ïve, triple-negative breast cancer patients according to BRCA1 status
Due to the abundant usage of chemotherapy in young triple-negative breast cancer (TNBC) patients, the unbiased prognostic value of BRCA1-related biomarkers in this population remains unclear. In addition, whether... (Source: BMC Medicine)
Source: BMC Medicine - January 9, 2024 Category: Internal Medicine Authors: Yuwei Wang, Gwen M. H. E. Dackus, Efraim H. Rosenberg, Sten Cornelissen, Leonora W. de Boo, Annegien Broeks, Wim Brugman, Terry W. S. Chan, Paul J. van Diest, Michael Hauptmann, Natalie D. ter Hoeve, Olga I. Isaeva, Vincent M. T. de Jong, Katarzyna J óź Tags: Research article Source Type: research
LASS2 enhances chemosensitivity to cisplatin by inhibiting PP2A-mediated β-catenin dephosphorylation in a subset of stem-like bladder cancer cells
The benefits of first-line, cisplatin-based chemotherapy for muscle-invasive bladder cancer are limited due to intrinsic or acquired resistance to cisplatin. Increasing evidence has revealed the implication of... (Source: BMC Medicine)
Source: BMC Medicine - January 9, 2024 Category: Internal Medicine Authors: Hongjin Shi, Zhiyong Tan, Bowen Duan, Chunming Guo, Chong Li, Ting Luan, Ning Li, Yinglong Huang, Shi Chen, Jixian Gao, Wei Feng, Haole Xu, Jiansong Wang, Shi Fu and Haifeng Wang Tags: Research article Source Type: research
Single-cell RNA sequencing in donor and end-stage heart failure patients identifies NLRP3 as a therapeutic target for arrhythmogenic right ventricular cardiomyopathy
Dilation may be the first right ventricular change and accelerates the progression of threatening ventricular tachyarrhythmias and heart failure for patients with arrhythmogenic right ventricular cardiomyopath... (Source: BMC Medicine)
Source: BMC Medicine - January 8, 2024 Category: Internal Medicine Authors: Mengxia Fu, Xiumeng Hua, Songren Shu, Xinjie Xu, Hang Zhang, Zhiming Peng, Han Mo, Yanyun Liu, Xiao Chen, Yicheng Yang, Ningning Zhang, Xiaohu Wang, Zirui Liu, Guangxin Yue, Shengshou Hu and Jiangping Song Tags: Research article Source Type: research
Human lifespan and sex-specific patterns of resilience to disease: a retrospective population-wide cohort study
Slower paces of aging are related to lower risk of developing diseases and premature death. Therefore, the greatest challenge of modern societies is to ensure that the increase in lifespan is accompanied by an... (Source: BMC Medicine)
Source: BMC Medicine - January 8, 2024 Category: Internal Medicine Authors: Joaquim Sol, Marta Ortega-Bravo, Manuel Portero-Ot ín, Gerard Piñol-Ripoll, Vicent Ribas-Ripoll, Eva Artigues-Barberà, Miquel Butí, Reinald Pamplona and Mariona Jové Tags: Research article Source Type: research
Benefits and challenges experienced by participants on long-term methadone maintenance treatment in China: a qualitative study
Methadone maintenance treatment (MMT) has been implemented in China for nearly two decades, with a significant decrease in the number of participants in recent years. However, there is a lack of comprehensive ... (Source: BMC Medicine)
Source: BMC Medicine - January 8, 2024 Category: Internal Medicine Authors: Xijia Tang, Wenxue Xiong, Wen Chen, Chijie Wang, Hexuan Wang, Boyu Li, Zirong Zhang and Li Ling Tags: Research article Source Type: research
Maternal pre-pregnancy body mass index and risk of preterm birth: a collaboration using large routine health datasets
Preterm birth (PTB) is a leading cause of child morbidity and mortality. Evidence suggests an increased risk with both maternal underweight and obesity, with some studies suggesting underweight might be a grea... (Source: BMC Medicine)
Source: BMC Medicine - January 5, 2024 Category: Internal Medicine Authors: R. P. Cornish, M. C. Magnus, S. K. Urhoj, G. Santorelli, L. G. Smithers, D. Odd, A. Fraser, S. E. H åberg, A. M. Nybo Andersen, K. Birnie, J. W. Lynch, K. Tilling and D. A. Lawlor Tags: Research article Source Type: research
Effects of glucagon-like peptide-1 receptor agonists on liver-related and cardiovascular mortality in patients with type 2 diabetes
Patients with type 2 diabetes (T2D) tend to have nonalcoholic fatty liver disease (NAFLD) with poorer prognosis. We performed this research to compare the risks of cardiovascular diseases, cirrhosis, liver-rel... (Source: BMC Medicine)
Source: BMC Medicine - January 4, 2024 Category: Internal Medicine Authors: Fu-Shun Yen, Ming-Chih Hou, James Cheng-Chung Wei, Ying-Hsiu Shih, Chii-Min Hwu and Chih-Cheng Hsu Tags: Research article Source Type: research
Supporting youth mental health with arts-based strategies: a global perspective
The devastating impact of youth mental health concerns is increasingly evident on a global scale. This crisis calls for innovative solutions that are sufficiently accessible, scalable, and cost-effective to su... (Source: BMC Medicine)
Source: BMC Medicine - January 3, 2024 Category: Internal Medicine Authors: Tasha L. Golden, Richard W. Ordway, Susan Magsamen, Aanchal Mohanty, Yifan Chen and T. W. Cherry Ng Tags: Opinion Source Type: research
